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  TMU103-AE1-B07

  Ru, H.

  11/1/14 → 10/31/16

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• TMU103-AE1-B05

  Hung, S.

  11/1/14 → 10/31/15

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 老年性聽力損失: Cisd2缺失會加速老化過程中的聽力損傷

  Chen, Y.

  11/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• 應用全民健保資料庫探討與追蹤臺灣人體生物資料庫個案健康狀況之研究

  Chung, M.

  10/23/14 → 12/31/17

  Project: A - Government Institution › f - Other (Funded by Government)

• 專業融入之服務學習模組教材開發—口述歷史加值服務學習教學模組

  Chiu, C. & Liu, M. F.

  10/6/14 → 4/5/15

  Project: A - Government Institution › d - Ministry of Education

• Study the Interactive Functions of Decoy Receptor 3 and Galectin-3 in Keratinocytes and Macrophages

  Lin, W.

  10/1/14 → 9/30/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Differential Machinery of Pluripotency Regulation in Stem Cells in Embryonic Stage and Somatic Cancers and Its Clinical Implications in Human Diseases---Crosstalk among Niche Growth Factor/Cytokine Signaling, Extracellular Matrix, and Epigenetic Netw (I)

  Huang, Y.

  10/1/14 → 9/30/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• TMU103-AE1-B03

  Lin, C.

  10/1/14 → 9/30/15

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• Micro-Scale Surface-Enhanced Raman Spectroscopy in Real-Time Single Living Cell Diagnostics (II)

  Peng, P.

  10/1/14 → 9/30/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• 103年度國民體適能檢測站設置實施計畫

  Kan, N.

  9/24/14 → 3/30/15

  Project: A - Government Institution › d - Ministry of Education

• 103年度「103-104年國民長期照護需要調查訪視控管作業」

  Huang, Y.

  9/11/14 → 6/30/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 北區高階生醫產業聚落及產業規劃-台灣遠距健康產業聚落發展先導計畫

  Yen, Y. & Chen, R.

  9/1/14 → 8/31/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

• Development of 3d-Printing Dynamic Orthosis-For Hemiplegic Lower Limbs( I )

  Chen, S.

  9/1/14 → 11/30/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• 103年度「含中藥材創意商品開發」

  Hou, W.

  9/1/14 → 4/30/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

• Novel Strategies to Target Long-Lived Plasma Cells for Treating Hemophilia a Inhibitors

  Liu, C.

  9/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Long-term follow-up study of health behaviors among adolescent cohort.

  Chiou, H., Chen, P., Chen, Y., Chang, H., Yang, S. & Chen, Y. C.

  9/1/14 → 12/31/14

  Project: A - Government Institution › c - Ministry of Health and Welfare

• A Phase I, First-In-Human, Dose-Seeking Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of Orally Administered MPT0E028 in Subjects with Advanced Solid Malignancies without Standard Treatment (I)

  Liou, J.

  9/1/14 → 9/30/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Valproate治療腦外傷病人的臨床研究

  Chang, C., Chiang, Y., Liao, K., Yang, S., Wu, C. & Chen, K.

  8/7/14 → 8/6/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

• Application of resilience engineering in emergent health care services

  蘇, 清., Chuang, S., 馬, 漢. & 蔡, 哲.

  8/7/14 → 8/6/15

  Project: A - Government Institution › a - National Health Research Institutes

• 國人口腔健康監測調查企劃案

  Tsai, H.

  8/4/14 → 12/31/14

  Project: A - Government Institution › c - Ministry of Health and Welfare

• Trends in Surgical Litigation and Media Coverage of Medical Malpractice: Implications for Medical Education

  Lyu, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Detecting Genetic Variants Based on a Random-Effects Model

  Cheng, K.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Three Steps of Fluorescence Resonance Energy Transfer Observation of Complexation of DNA/Drug/Polymeric Micelles on Cornea Transport

  Liaw, J.

  8/1/14 → 12/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Unraveling the Impact of Deletion of Androgen Receptor on Brain Trauma

  Yang, L.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular Mechanisms of PARP-1 in Regulating NLRP3 Inflammasome Activation

  Lin, W.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• 《Essence of Decision: Explaining the Cuban Missile Crisis》Translation and Annotation Project

  Chang, K.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Exploratory Study of Self-Identity and Medical Professionalism among Medical Students (II)

  Chiu, C.

  8/1/14 → 12/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Methodology Study of Integrating Systems Thinking and Bayesian Network in Health Policy

  Chuang, S.

  8/1/14 → 11/30/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of CD24 in TNF-Alpha-Inhibited Erythroid Differentiation

  Huang, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of a Computerized Adaptive Testing of the Health Literacy in Stroke Rehabilitation

  Hou, W.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌是目前世界上女性癌症病患中為數最多的癌症之ㄧ。腺病毒蛋白type 5 E1A (E1A)和許多抗腫瘤作用有關，曾於多種癌症如乳癌、卵巢癌及頭頸癌之病患進行臨床基因治療試驗。許多的研究指出E1A具有多項抗腫瘤的功能，包括抑制腫瘤的發生、增加腫瘤細胞對於化療藥物的感受性以及減少腫瘤轉移的現象。腫瘤的轉移對於癌症患者的死亡率有極大的影響當然也包括了乳癌的患者。E1A於抑制腫瘤發展的過程中具有多重生物學上的意義，這也促使我們想要釐清E1A抑制癌症的機制。因此，我們對於了解E1A抑制癌症轉移相關的分子機制感到有興趣，並期望藉以作為未來改進乳癌病人臨床試驗的基石。我們初步的實驗結果顯示，E1A可以有效的抑制Glucose-regulated protein 78 (GRP78)這種已被廣泛報導和腫瘤惡化及轉移相關的蛋白的表現。 提出此研究計劃之目的在於詳細探討E1A所造成的抑制癌轉移作用中，GRP78所扮演的生物功能及其調控的機轉。為了達到此目的，我們將著重於E1A如何調控GRP78表現並進而展現對乳癌轉移的抑制作用。以下為此項研究計畫的四大主要目標： 目標一：探討GRP78在E1A所抑制之癌細胞移行及侵入作用中所扮演的角色 目標二：研究E1A抑制GRP78表現之分子機轉 目標三：於動物模式中驗證GRP78的表現對於E1A抗腫瘤作用的影響 目標四：探討GRP78及其相關分子的表現在乳癌病人的臨床重要性 完成以上的主要目標能夠幫助我們對於E1A之抗腫瘤轉移作用建立更加詳細的分子訊息傳遞機制。另外，藉由此研究計畫的新發現也許可以對未來發展癌症治療上提供更多具有潛力的標的物。

  Wang, W.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the Function and Regulation of miRNAs in Pancreatic Cancer Progression (I)

  Huang, M.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Functional Investigation of Heat Shock Protein in Esophageal Squamous Cell Cancer with Implications in Prognostic Prediction and Therapeutic Targeting

  Tzao, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effect of Vasopressin Receptor Agonist and Antagonist on Pulmonary Vein and Atrial Arrhythmogenesis

  Huang, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• CXCL5/CXCR2/JNK Axis Is the Shared Pathway of Neuroinflammation and Microvascular Damage That Contributes to White Matter Injury in the Immature Brain

  Huang, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of CISD2 in the Female Reproductive System of Mammal

  Chang, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• 族群口腔健康

  Huang, Y.

  8/1/14 → 1/31/15

  Project: A - Government Institution › d - Ministry of Education

• 中山區健康生活型態調查

  Chen, R.

  8/1/14 → 10/30/14

  Project: A - Government Institution › f - Other (Funded by Government)

• 抗氧化防禦基因標籤單核?酸多形性、氧化壓力生物標記與冠狀動脈心臟病之相關性(2/2)

  Yeh, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Effect of Long Acting GnRH Agonist Treatment on Mitochondrial Function in

  Tzeng, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Exercise Intentions and Behaviors of Students in Metropolitan Areas---A Longitudinal Study

  Lee, P.

  8/1/14 → 1/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Novel Therapeutic Agents for Herceptin Resistance Breast Cancer Cells through Targeting Nicotinic Acetylcholine Receptors

  Lee, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• 健康產業行銷與溝通

  Teng, N.

  8/1/14 → 1/31/15

  Project: A - Government Institution › d - Ministry of Education

• The Effect of Blood Sugar Regulation and Molecular Mechanism by White Potato Extract

  Li, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• An Investigation of the Effects of Tea Component on the Inhibition of Leukocyte Nicotinic Acetylcholine Receptor Expression on Breast Cancer Patients

  Tu, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Genetic Polymorphisms in microRNA and Risk of the Post-Thrombolytic Hyperglycemia in Acute Ischemic Stroke and Its Prognosis Study

  Hsieh, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Study of Therapeutic Effects for Stroke with Phenserine, an Amyloid Precursor Protein Inhibitor, in Rodent Focal Cerebral Ischemia Model(2/3)

  Chang, C. & Chiang, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › a - National Health Research Institutes

• Study on the Mechanism of Cross-Talk between Ahr and Autophagy, and Autophagy---Associated Physiological or Pathological Phenomenon on Vascular and Airway Systems (I)

  Li, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of CCR5/RANTES in Neurodegeneration

  Chou, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role of Synovium in Osteoarthritis Progress and Cartilage Regeneration

  Yang, K.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology