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• 乳癌細胞α9尼古丁受體作為新穎靶向RNA奈米藥物與T細胞療法之臨床轉譯研究-探討α9尼古丁受體基因表現在乳癌病人血液循環腫瘤細胞/游離DNA於乳癌治療的應用(1/3)

  Tzeng, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討孩童肥胖，青春期發育與胰島素阻抗之基因生活型態影響因素(3/3)

  Chen, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 進展性胰臟癌新穎增進免疫療法的治療策略與生物指標-對免疫療法併用方案節拍式化療或射頻燒灼療法之胰臟癌患者進行基因標記和免疫基因組庫之鑑定與分析(2/3)

  Chang, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 枸杞多醣對鐵沉積及其相關病症之影響

  Wu, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 嵌合抗原受體T細胞用於治療人類卵巢癌的免疫療法(2/3)

  Liu, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以機器學習辨識兒童注意力不足及注意力不足過動症

  Chiu, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 長散在核元件-1甲基化及DNA甲基化標記5-甲基胞嘧啶與5-甲基-2'-脫氧胞?濃度及尿液總砷濃度與慢性腎臟病的相關性

  Hsueh, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 單側唇?裂患者的鼻道阻塞的評估與治療2(1/2)

  Chen, K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討在慢性腎臟疾病中經由抑制內皮素轉化酶調節前列腺素E2受體和自體吞噬作用的治療潛力之機轉(1/3)

  Lin, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 合成可雙重抑制組織蛋白去乙醯酶6與熱休克蛋白90，並同時調節PD-L1之雜環類抗癌化合物

  Lai, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建立可偵測多重膜蛋白突變之蛋白基因體平台（延續計畫）

  Han, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 代謝異常鐵過量症狀與男性睪固酮合成機制:高脂高鐵飲食所扮演的角色(3/3)

  Chang, J.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討PCTK1激?蛋白在大腸直腸癌發展的角色及其調控機制(延續計畫)(3/3)

  Wei, P.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 整合臨床血液透析高分辨率生物活體脈衝光驅動鹵素鈣鈦礦成像於微觀血管彈性研究與紅外線照射系統

  Liou, J.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建置與評估可擴充式機器學習演算法之重症醫療資訊平台

  Lo, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 抑制site-1蛋白酶引發肝癌細胞自我吞噬之研究

  Yang, P.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發1,3-二芳基取代之五元雜環作為抗胰臟癌劑(2/3)

  Lee, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 絲氨酸/蘇氨酸蛋白激酶(SIK3)參與乳癌致癌過程的分子機制探討

  Chen, L.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展三功能抗體(EGFR/CD3/mPEG)修飾之聚乙二醇-免疫增敏奈米藥物以主動標靶毒殺大腸癌並同時強化體內 T 細胞於腫瘤微環境抗癌功效之創新協同療法-發展新型聚乙二醇-免疫增敏奈米藥物載體以毒殺大腸癌並強化腫瘤區域T細胞之抗癌功效(1/3)

  Liu, D.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 枸杞多醣與辣椒素對潰瘍性結腸炎修復之影響-探討抗氧化、抗發炎、抗細胞凋亡 、止痛、腸通透率、細胞防禦及菌相調節機制(2/3)

  Chao, J. C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Glyoxalase 1 基因控制對肺癌惡性肋膜積水中代謝壓力介導產生的細胞上皮間質轉化與癌轉移的影響機轉(1/3)

  Chung, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 科普活動：小小AD8失智檢測先鋒—從書寫祖父母的生命故事書串起認知神經科學與失智檢測(主題一)

  Hsu, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 從食安風險暴露之角度探討非營養性甜味劑對女性生殖狀況之影響-非營養性甜味劑在妊娠期糖尿病發生所扮演的角色(1/3)

  Wu, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新穎性選擇性HDAC抑制劑之抗癌藥物開發與藥理機轉探討(3/3)

  Pan, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建立智慧神經加護病房資料庫(MiNiC)(2/3)

  Lin, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• ASPM-PAR-PCP訊息軸於侵犯性癌幹細胞造成癌轉移的角色與其標靶治療(2/3)

  Tsai, K. K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 嗜伊紅性白血球陽離子蛋白衍生之細胞穿透胜肽對於調節過敏性發炎之研究- 促進STAT-6反義RNA之運送與表現(2/3)

  Lee, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 降解型細胞自噬藉由促進微小RNA miR-449a表現量抑制大腸直腸癌之進程進而發展治療大腸癌之新策略(1/2)

  Wu, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建構定量系統生理基礎藥動模型以評估腸道菌叢對口服藥物代謝影響及協助奈米膠體處方之開發(1/3)

  Hsieh, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 在動物模式下發展穿顱干擾波電刺激新技術應用於中風膀胱功能障礙復健治療(1/3)

  Peng, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討富含半胱氨酸的酸性分泌蛋白在脊椎神經管內黃韌帶肥厚之角色

  Lee, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用人工智慧虛擬篩選平台鑑定DNA聚合?theta之小分子抑制劑和評估其對於轉移型去勢抗性之攝護腺癌的治療效果(2/3)

  Lin, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 應用蛋白質補充劑於慢性中風患者之復健訓練

  Lin, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討小分子核糖核酸和腸道微生物在中風後血管性認知功能障礙所扮演的角色(3/3)

  Chiou, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 針對癌症治療研發與活性最適化蛋白質激酶抑制劑(2/3)

  Hsu, K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌細胞受體專一性RNA適體奈米質粒誘發第三型玻尿酸合成酵素的抗癌機制探討(1/3)

  Tu, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 配對式神經調控模式應用於脊髓損傷者之前瞻神經復健技術開發-子計畫一: 在脊髓損傷動物模式下探討配對式神經調控之作用機制與療效(2/3)

  Peng, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 攝護腺癌之精準代謝治療(3/3)

  Kung, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 天然物實驗室的自動化設計(3/3)

  Lee, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 活性維生素D經由非典型高等糖化終產物受體與纖維母細胞生長因子受體訊息調控心臟纖維母細胞與糖尿病心臟纖維化之關聯(3/3)

  Lee, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發混合型機器學習之代謝物滯留時間預測模型用於辨識液相層析串聯質譜儀實驗之代謝物(1/2)

  Wang, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以深度學習分析臨床特徵及胚胎品質以提升人工受孕懷孕率之系統性預測方法開發

  Su, E. C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 脂肪激素內脂素對子宮肌瘤增生及微環境影響:分子機制探討及精準營養應用之研究(1/3)

  Hsia, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 雙極症患者視網膜血管和頸動脈粥狀化、視神經層厚度和腦體積之關聯及影響因素

  Tsai, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討NPC2基因調控肝癌細胞內游離型膽固醇恆定在sorafenib抗藥性之角色(2/3)

  Liao, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新穎癌幹細胞侵犯腳治療標靶之整合性蛋白質體、基因體、小分子與功 能篩選：聚焦細胞表面AMFR於侵犯性消化道癌症治療標的(1/3)

  Tsai, K. K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 高風險住院中老年人出院後照護地點與銜接服務使用對其健康與醫療利用之長期影響(2/3)

  Chi, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 天然物對鉑類抗藥性膀胱癌之治療潛力及其分子作用機轉探討(2/3)

  Chen, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 吳茱萸生物鹼rutaecarpine調控血小板活化及自噬作用的機轉探討以及在自體血栓塊引起腦中風鼠的活性評估: NF-kB在無核細胞中的角色(2/3)

  Sheu, J.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• (教學實踐) 以「東亞近代史」課程提升醫學大學學生「多元文化認知」與「敘事能力」之研究

  Tseng, L.

  8/1/20 → 7/1/21

  Project: A - Government Institution › d - Ministry of Education