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• 桑黃天然物hispolon及其結構衍生物延緩老化與神經退化疾病的研究:從體外試驗到體內動物模式(3/3)

  Hou, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建構空氣汙染物、易感受性基因及傳統危險因子對於缺血性中風風險之個人化精準預測模式(2/3)

  Chiou, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新穎性選擇性HDAC抑制劑之抗癌藥物開發與藥理機轉探討(3/3)

  Pan, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 早幼粒細胞白血病鋅指蛋白(PLZF)對腦部發育的多重功能之探討(3/3)

  Lee, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 絲氨酸/蘇氨酸蛋白激酶(SIK3)參與乳癌致癌過程的分子機制探討

  Chen, L.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討ARE結合蛋白質與選擇性聚腺甘酸化作用在人類大腸直腸癌上所扮演的角色(3/3)

  Liang, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以上皮間質轉化的觀點來探討臨床濃度Lidocaine對大腸癌腫瘤移動的影響

  Lin, J. A.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 紫杉醇調控血小板活化、細胞凋亡和自我吞噬之分子機轉探討:體內及體外試驗(1/3)

  Lu, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• RAB3C對大腸直腸癌之抗藥性與腫瘤免疫反應影響之探討(1/3)

  Chen, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 藉由調控神經包網結構來改善早期社交孤立所誘發於模棱兩可的資訊下異常恐懼記憶連結的形成(1/3)

  Yang, C. H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 芳香烴受體於眼科疾病之治療潛力機制探討-探討芳香烴受體活化在青光眼病程的視網膜保護角色(1/3)

  Hsiao, G.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 透過感恩行為影響學生在大體解剖學實驗課程中的情緒感受與調適並強化家訪的效果

  Chiou, R.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌細胞受體專一性RNA適體奈米質粒誘發第三型玻尿酸合成酵素的抗癌機制探討(1/3)

  Tu, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用轉錄體學與蛋白質體學方法探討膀胱癌對鉑類藥物產生抗藥性之分子機轉研究並開發新的治療策略(第二年)

  Chen, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建立類神經網路模型以評估手術病患發生呼吸中止與低血氧的風險

  Chang, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 闡明Hiltonol為主的複合式用藥在肺癌生長，轉移和腫瘤微環境中的作用。

  Chang, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 結合奈米診斷治療、影像免疫基因圖譜與人工智慧於原發性與再復發膠質母細胞瘤之研究-開發新穎結構小分子抑制劑用來抑制血管生成和腫瘤微環境以治療原發性及復發性多型性神經膠質母細胞腦瘤患者(2/3)

  Huang, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建立探討膜蛋白折疊的研究平台(2/3)

  Chang, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以新式片狀細胞工學製備自體片狀心肌細胞及其應用在缺血性心臟病的動物模式

  Tseng, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 標靶B型肝炎誘發之肝癌腫瘤生成與Sorafenib抗藥性之微環境：聚焦發炎激素與癌幹細胞特性之轉譯精準醫學研究與臨床意義-探討微環境發炎細胞激素與基因後生調節於B型肝炎病毒誘導之肝癌表現多能性幹細胞基因OCT4與Sorafenib抗藥性之調控機制與其臨床意義(3/3)

  Huang, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用結構生物學與蛋白質體學探討植物菌質體 PHYL1 交互作用蛋白質

  Wang, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 青少年期慢性睡眠剝奪對認知、情緒與壓力調適功能之影響:動物模式與人類世代之整合研究-青少年期慢性睡眠剝奪對認知、情緒與壓力調適功能之影響:健康青少年族群之觀察追蹤與介入研究(2/3)

  Lee, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以體外循環腫瘤細胞擴增系統發展兒童神經腫瘤精準醫療策略

  Liu, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以循環腫瘤細胞預測肝癌治療反應及其機制探討

  Chiou, J.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研究BTK/HER2信號通路在HER2陽性乳腺癌生物特性角色: 調控T細胞的效應及逆轉賀癌平抗藥性的分子機制(2/3)

  Chao, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建構定量系統生理基礎藥動模型以評估腸道菌叢對口服藥物代謝影響及協助奈米膠體處方之開發(1/3)

  Hsieh, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討黃腐醇合併降血糖藥是否可調控粒線體失常並經由活化未摺疊蛋白反應所激發之AMPK-NRf2-ARE-Glo1路徑來逆轉雙羰基壓力導致之糖尿病腎脂毒性

  Chen, K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展一新型藥物作為改善肥胖及肥胖引發糖尿病導致腎病變症候群之轉譯醫學研究(2/3)

  Lin, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討TCF7L1對前列腺癌神經內分泌分化之分子機轉與臨床意義

  Wen, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討多環芳香烴受體缺陷重啟多能細胞特性之新穎路徑與應用

  Li, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 社區民眾血管硬化程度分布，以及血管鈣化硬化粥狀硬化與代謝發炎相關生物標記及其基因多型性關連性研究(3/3)

  Bai, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 雙極症患者視網膜血管和頸動脈粥狀化、視神經層厚度和腦體積之關聯及影響因素

  Tsai, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 結合奈米診斷治療、影像免疫基因圖譜與人工智慧於原發性與再復發膠質母細胞瘤之研究-以機器學習的方法導入影像基因圖譜用以研究膠質母細胞瘤與免疫相關之基因表現(2/3)

  Chen, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• CXCL6/CXCL1 axis在PDK1訊號路徑介導的放射抗性肝細胞癌之分子機制探討

  Tsai, J.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 藉由中孔洞二氧化矽奈米粒子的一種替代原位疫苗接種方法用於癌症免疫治療

  Chen, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 從食安風險暴露之角度探討非營養性甜味劑對女性生殖狀況之影響-非營養性甜味劑在妊娠期糖尿病發生所扮演的角色(1/3)

  Wu, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigating Dopaminergic Influences on Brain-State Switching and Its Relation to Human Behaviour through Translational Neuroimaging(2/2)

  Duncan, N.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 粒線體蛋白表現於AKI-AKD -CKD發展進程之角色及其潛在治療策略

  Hsu, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用超高速藥物篩選平台鑑定活化轉錄因子3之小分子活化劑及其對慢性腎臟病之治療效果

  Chen, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Building a Comprehensive Model of Individual Variations in Responsiveness to Electrical Brain Stimulation(1/4)

  Tseng, P.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展干擾染色質複製時期基因體穩定性之藥劑 (第二至四年)

  Lee, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 瘦體素胜?衍生物OB3抑制瘦體素誘導的原發性肝細胞癌細胞增生之研究

  Yang, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 寡糖經由調節發炎反應來保護急性腎損傷的機制研究

  Chen, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用藥物基因體發展急性登革熱病毒感染期間免疫反應之臨床診斷：探討T細胞組庫和C-型凝集素基因家族之遺傳變異(1/3)

  Chang, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 配對式神經調控模式應用於脊髓損傷者之前瞻神經復健技術開發-子計畫三：運用跨模態多項次神經影像技術探討神經調控模式對脊髓損傷者之神經可塑性與功能變化(2/3)

  Chan, W. P.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• (教學實踐) 系統性強化高齡藥事照護之進階藥學實習評估

  Chang, E. H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › d - Ministry of Education

• 進展性胰臟癌新穎增進免疫療法的治療策略與生物指標-對免疫療法併用方案節拍式化療或射頻燒灼療法之胰臟癌患者進行基因標記和免疫基因組庫之鑑定與分析(2/3)

  Chang, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 住院急性胰臟炎使用鴉片類處方藥物病人之持續性使用分析

  Chen, S. H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Bilateral Parietal-Prefrontal and Glutamatergic Activity in Schizophrenia Patients--Fmri, Rsmri, and Mrs Investigation

  Lane, T. J., Lin, I., Tseng, P. & Lu, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the Benefical Effects and Mechanisms of Probiotics and Exercise Intervention Strategies in 6-Ohda Induced Parkinson'S Disease Rat(1/3)

  Huang, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology