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• b - Ministry of Science and Technology

  An Investigation of the Effects of Tea Component on the Inhibition of Leukocyte Nicotinic Acetylcholine Receptor Expression on Breast Cancer Patients

  Tu, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Leukocytes 100%
  • Tea 92%
  • Breast Neoplasms 87%
  • Nicotine 31%
  • Capsules 28%

• Mechanistic Studies of Renal Cell Carcinoma: from Rhoa-Mediated Expression of Cd44-Targeting Micrornas to the Development of Biomarkers and Therapies

  Juan, S.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Renal Cell Carcinoma 100%
  • MicroRNAs 67%
  • Biomarkers 15%
  • Simvastatin 14%
  • Epithelial Cells 13%

• 探討芳香烴受體(AhR)改變血管內皮細胞功能之新角色：經由表觀基因或後轉譯修飾(細胞週期蛋白/內皮細胞一氧化氮合成酉每)的調控與白蘆黎醇/史達汀臨床治療及應用(2/3)

  Juan, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Identification a Novel Circadian Clock-Mediated Cell Dividing in Hepatocyte: Mechanistic Exploration for Physiological and Pathological Functions in Liver(I)

  Chao, H.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Association between Plasma Folate and Selenium Concentrations, Gene Polymorphisms of Selenoprotein and One Carbon Metabolism Related Enzymes and Developmental Delay in Preschool Children

  Hsueh, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Preschool Children 100%
  • Arsenic 88%
  • Selenoproteins 47%
  • Selenium 45%
  • Cystathionine 38%

• 102 年東南亞區域共同研究暨培訓型國際合作計畫—社區精神復健合作研究平台與專業人員培訓工作坊

  Tsai, D.

  6/1/13 → 12/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Cytotoxicity and Application on Drug Resistant Cells of Halide Derivatives of Rutaecarpine

  Lin, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Evodiamine 100%
  • Poison 67%
  • Halide 66%
  • Topoisomerase Inhibitor 49%
  • Antimicrobial Agent 40%

• The Effect of Long Acting GnRH Agonist Treatment on Mitochondrial Function in

  Tzeng, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • hormone agonists 100%
  • mitochondria 91%
  • pathophysiology 42%
  • granulosa cells 38%
  • agonists 32%

• Development the Prediction Model of Vascular Dementia to Improve the Quality of Care among Patients with Acute Stroke

  Chien, L.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 骨質疏鬆及肌少症影像人工智能分析計畫

  Kuo, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討 ABCC3 調控基因/lncRNA 網絡，進而評估其抑制藥物 Fidaxomicin 作為增強 temozolomide 對腦瘤毒殺能力佐劑之可行性

  Chen, K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 產學合作計畫－開發農藥快篩之表面增強拉曼光譜之資料庫

  Liu, Y.

  6/1/20 → 5/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Detecting Genetic Variants Based on a Random-Effects Model

  Cheng, K.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • interaction 100%
  • inclusion 97%
  • Genetic information 93%
  • Group 85%
  • statistics 52%

• Cross-Board Survey of Medical Professionalism: the Effect of Cultural Context (Ii)

  Chiu, C. & Tsai, D.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • professionalism 100%
  • Indonesia 22%
  • civil society 22%
  • bioethics 14%
  • curriculum 14%

• Big Data Analytics to Build Risk Assessment Models of Postoperative Complications for Patients with Chronic Pulmonary Disease

  Lin, C.

  8/1/16 → 10/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Postoperative Complications 100%
  • National Health Programs 81%
  • Risk Assessment 64%
  • Big Data 52%
  • Support Vector Machine 47%

• Research of Harmful Substances in Water on Human Reproductive and Neuronal Cells Toxicity Translation Assessment (I)

  Mai, F.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • germ cells 100%
  • neurons 98%
  • spectrometers 87%
  • toxic substances 76%
  • translation (genetics) 68%

• Electrophysiological Activity and Functional Correlates in Female Pelvic Floor Muscles(2)

  Yang, J.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • muscles 100%
  • urinary incontinence 51%
  • electromyography 38%
  • muscle contraction 36%
  • testing 5%

• Study on the Immunopathological Changes in the Brains of Blimp1 Transgenic and Conditional Knockout Mice Infected with Angiostrongylus Cantonensis by Using Nuclear Medicine Imaging Evaluation Model

  Cheng, P.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Angiostrongyliasis 100%
  • Meningoencephalitis 65%
  • Angiostrongylus cantonensis 55%
  • Positive Regulatory Domain I-Binding Factor 1 44%
  • Meningitis 42%

• A Translational Investigation of the Role of Manganese Superoxide Dismutase (Mnsod) in M2-Macrophages for Colon Cancer Stem Cell Generation and Preclinical Evaluation of Mndso Modulators for Potential Colorectal Cancer Therapeutics

  Lee, W.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Superoxide 100%
  • Tumorigenic 15%
  • Adjuvant 12%
  • Resistance 6%

• A Methodology Study of Integrating Systems Thinking and Bayesian Network in Health Policy

  Chuang, S.

  8/1/14 → 11/30/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • health policy 100%
  • methodology 33%
  • subsystem 29%
  • regional administration 20%
  • health care services 14%

• Investigation of Nuclear microRNA Signatures and Their Functional Effects on Glioblastoma Multiforme Pathology

  Chen, K. & Shih, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Glioblastoma 67%
  • Temozolomide 54%
  • Glioma 23%
  • Genes 12%

• 電漿活化水在綠色化學與神經醫學上的創新應用(3/3)

  Liu, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Study of Content of Identity and Identification--The Interplay of Individual and Organizational Level

  Chiu, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • physician 100%
  • manpower 36%
  • surgery 34%
  • pathology 31%
  • accreditation 30%

• In Vi Vo and in Vi Tro Screening of the Dyslipidemic Antihypertensives, Studying the Mechanism to Modulate Signaling Srebp and Ppar in the Renal Cells, and Investigating the Cotherapy with Mountain Celery Seed Aqueous Extract in Reducing Worsen Renal F

  Chen, K.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Apium 100%
  • Seeds 63%
  • Kidney 55%
  • Antihypertensive Agents 47%
  • Sterol Regulatory Element Binding Proteins 31%

• Investigation on the Improvenment of Solanum Nigrum and Paris Polyphylla for Inhibitions of Metastasis and Drug Resistance Mediated by Exosomes from Breast Cancer Cells

  Tai, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Drug 100%
  • Antineoplastic Agent 84%
  • Marker 83%
  • MicroRNA 58%
  • Protein 19%

• Combine Anesthesia Information System with Artificial Neural Networks to Develop the Surgical Complication Pre-Warning System

  Lin, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • postoperative complications 100%
  • neural networks 29%
  • health status 17%
  • surgery 16%
  • anesthesia 15%

• Study of Prevention, Control, Genotyping and Risk Factors of Intestinal Parasitic Infections and Head Lice in Schoolchildren in Cambodia

  Liao, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study on the Inhibitory Effects of Saponins Obtain from Different Paris Polyphylla Strains on Progression in Triple Negative Breast Cancer Induced by Neurotransmitters

  Tai, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Saponin 100%
  • Neurotransmitter 64%
  • Adjuvant 36%
  • MicroRNA 35%
  • Gracillin 28%

• Journey of Professional Identity Building of Young Physicians-- Examining the Impact of Gender, Stress, Duty Hours, and Work Loading.

  Chiu, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Modulation of Tumor Microenvironment by Nucleic Acid Chimeras as a New Paradigm for Adjuvant Cancer Therapy

  Yeh, S.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • neoplasms 100%
  • cytokines 66%
  • neoplasm progression 60%
  • neoplasm cells 55%
  • chimerism 45%

• Development of measurement technology of surface-enhanced Raman spectroscopy for detection of biomolecules

  Liu, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Raman spectra 100%
  • electrochemistry 71%
  • noble metals 22%
  • bioinstrumentation 16%
  • sensitivity 14%

• Evaluation of the Mechanism of Post-Traumatic Immunosuppression---The Role of TLR4 Trafficking and microRNA

  Lin, J. A.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • immunosuppression 100%
  • bones 72%
  • monocytes 53%
  • inflammation 46%
  • orthopedics 45%

• Exploratory Study of Self-Identity and Medical Professionalism among Medical Students (II)

  Chiu, C.

  8/1/14 → 12/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • professionalism 100%
  • medical student 35%
  • empathy 24%
  • curriculum 21%
  • role model 13%

• Preparation Mechanism and Application of Innovatively Plasmon-Induced Activated Liquid Water with Reduced Hydrogen-Bonded Structure(2/3)

  Liu, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hot Electron 100%
  • Antiaging 75%
  • Hydrogen Bond 63%
  • Dialyzer 53%
  • Metal Nanoparticle 52%

• Modulation of Tumor Microenvironment by Nucleic Acid Chimeras as a New Paradigm for Adjuvant Cancer Therapy

  Yeh, S.

  1/1/12 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • neoplasms 100%
  • cytokines 66%
  • neoplasm progression 60%
  • neoplasm cells 55%
  • chimerism 45%

• Research on Development of Clound Computing Platform for Decision Support Systems Healthcare by Healthcare Big Data and Analytics

  Chiang, I.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Big data 100%
  • Cloud computing 32%
  • Decision support systems 19%
  • Information management 17%
  • Visualization 14%

• Wearable Medical Modnles with Far Infrared Light and Microwave Pules Measurement (Emphasis Theme:A3)(3/3)

  Hsu, Y.

  5/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 運用凝血?作為基楚之癒合組織工程：與韌帶及肌腱組織癒合為例

  Hsieh, M.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Contextualization of Acgme Milestone Project and Its Integration with Entrustable Professional Activities (Epas) in Taiwan – a 3-Stage Educational Implementation in Anesthesiology Based on 4 Teaching Hospitals

  Chen, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Taiwan 100%
  • educational reform 41%
  • learning 40%
  • content analysis 29%
  • expert 25%

• 以資料探勘技術進行大數據分析，建立術中低血氧與術後休克風險預測模型(1/2)

  Lin, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Comparison of Complications and Mortality after Surgery between General Anesthesia and Regional Anesthesia in the Elderly(2/2)

  Liao, C.

  8/1/16 → 10/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Conduction Anesthesia 100%
  • General Anesthesia 89%
  • Elderly 42%
  • Mortality 35%
  • Postoperative Complications 30%

• Investigation of the Mechanism of Post-Fracture Immune Dysfunction and the Role of Statin in Its Prevention and Treatment Strategy: from Bench to Bedside(2/2)

  Lin, J. A.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Wounds and Injuries 100%
  • MicroRNAs 80%
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors 77%
  • 3' Untranslated Regions 65%
  • Immunosuppression 57%

• The Build of Functional Protein Molecular Shuttles by Using a Genetically Engineered Kinesin and Nucleic Acid Aptamers - with the Integration of the Cost-Effective Microscopic Imaging System and Micro Fluidic Channel Chips

  Kuo, T.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Kinesin 100%
  • Microtubules 50%
  • Nucleic Acids 12%
  • Adenosine Triphosphate 10%
  • Nucleotide Aptamers 9%

• Reactions of NSAIDs (Mefenamic Acid and Diclofenac) by O3/GAC Processes---Intermediates, Pathway and Kinetic Models

  Chang, E.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • acid 100%
  • drug 86%
  • ozonation 57%
  • PPCP 35%
  • oxidation 34%

• To Study the Correlation between Serum Markers of Oxidative Stress, Inflammation, and Endocrine-Disrupting Chemicals (Edcs) and Their Impact on the Menstrual Cycle and Reproductive Hormone in Taiwanese Women

  Hsu, M.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Endocrine Disruptors 100%
  • Oxidative Stress 40%
  • Inflammation 39%
  • Polycystic Ovary Syndrome 37%
  • Biomarkers 36%

• Expression of Deptor Gene and Its Effect on the Early Development of Liver and Gut in Zebrafish

  Cheng, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • digestive system 100%
  • Danio rerio 84%
  • liver 72%
  • rapamycin 53%
  • immunohistochemistry 41%

• 價創計畫：微創手術AI輔助影像辨識系統-以婦科子宮動脈阻斷術為模型

  Chen, C.

  7/1/20 → 12/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Effects and Molecular Mechanisms of Phthalates (DEHP 和DBP) on the Mitochondrial Function and Genetic Regulation in Ovarian Granulosa Cells and Mouse Embryo(2/2)

  Tzeng, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • phthalates 100%
  • granulosa cells 23%
  • reproductive system 17%
  • mice 14%
  • embryo (animal) 10%

• 闡明動力素分子馬達蛋白質(kinesin molecular motor protein) 之關節區團 （hinge domain）的結構和功能—為建構實用的動力素分子載具鋪路

  Kuo, T.

  7/1/19 → 2/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Use of Nucleic Acid Aptamer to Build Kinesin Molecular Shuttles

  Kuo, T.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Proteins 100%
  • Scaffolds 77%
  • Nanoscience 36%
  • Nucleic acids 31%
  • Adenosinetriphosphate 28%