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• b - Ministry of Science and Technology

  Research of Biomedical Mg-Zr Alloys on Maxillofacial Reconstruction

  Peng, P., Ou, K. & Huang, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • bones 100%
  • orthopedics 91%
  • biodegradation 52%
  • Taguchi methods 51%
  • degradation 50%

• Development of a Computerized Adaptive Testing of the Health Literacy in Stroke Rehabilitation.

  Hou, W. & Chen, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Health Literacy 100%
  • Stroke Rehabilitation 86%
  • Psychometrics 23%
  • Stroke 21%
  • Rehabilitation 19%

• Modifying the Impact of Maternal Psychopathology on Adverse Infant Health Outcomes---Effects of Paternal Involvement and a Trial on Positive Activity Intervention

  Chen, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Study the Role of Multidrug Resistance Protein 4 on Induction of Aspirin Resistance in Type 2 Diabetes Mellitus

  Lu, W.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Subfamily B ATP Binding Cassette Transporter 100%
  • Aldehyde Reductase 68%
  • Aspirin 64%
  • Platelet Activation 25%
  • Blood Platelets 25%

• Health Internet of Things (Hiot) Medicine, Research &Amp; Industry( I )

  Li, Y.

  2/1/17 → 1/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Internet of things 100%
  • Industry 52%
  • Clinical research 33%
  • Wearable technology 26%
  • Data Analytics 26%

• The Role of Respiratory Rate Variability and Heart Rate Variability in Predicting Adverse Event in the Hemodialysis Patients

  Shabbir, S. A.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Respiratory Rate 100%
  • Vital Signs 48%
  • Heart Rate 42%
  • Renal Dialysis 31%
  • Physiologic Monitoring 15%

• Studies on the Mechanisms of Histamine N-Methyltransferase (Hnmt)-Mediated Herceptinr Drug-Resistance in Breast Cancer Cells(3/3)

  Ho, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histamine N-Methyltransferase 100%
  • Trastuzumab 89%
  • Breast Neoplasms 16%
  • Tissue Array Analysis 9%
  • Gene Expression Profiling 8%

• Developing an Intelligent Assessment and Rehabilitation System for Bilateral Upper Limb Coordination Control of Upper Extremity in Hemiparetic Subjects

  Lin, C. & Lai, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Patient rehabilitation 100%
  • Recovery 25%
  • Feedback 11%
  • Wearable technology 10%
  • Connecting rods 6%

• The Effect of Physical Exercise Program on Pro-Inflammatory and Anti-Inflammatory Cytokines in Patients with Chronic Obstructive Pulmonary Disease

  Ho, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Obstructive Pulmonary Disease 100%
  • Anti-Inflammatory Agents 45%
  • Exercise 32%
  • Cytokines 23%
  • Interleukin-6 19%

• The Effects of the Apoe4 Allele on Cerebral Structural and Functional Connectivity- a Diffusion Tensor Imaging and Resting-State Mri Study

  Chen, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Alleles 100%
  • Apolipoproteins E 90%
  • Brain 50%
  • Short-Term Memory 40%
  • Magnetic Resonance Imaging 33%

• The Role of SUV39H1 in Control of Inflammatory Genes and in Chronic Inflammation of Copd

  Lee, K., Feng, P. & Chuang, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Obstructive Pulmonary Disease 100%
  • Inflammation 60%
  • Blood Cells 33%
  • Histone Deacetylase 2 32%
  • Glucocorticoids 27%

• To See Is to Believe-Visualization of the Spectrum on Chronic Kidney Disease

  Jian, W.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Health care 100%
  • Data visualization 75%
  • Patient treatment 50%
  • Disease control 49%
  • Health insurance 49%

• Circuits of IGF-1R and Niche Signaling (Hypoxia/Inflammation) in Stem Cell Transformation and Its Clinical Implication of Molecular Target Therapy (Model of Germline Stem Cells)

  Huang, Y.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neoplastic Stem Cells 100%
  • Stem Cells 86%
  • Hypoxia 55%
  • Inflammation 34%
  • Seminoma 29%

• Role of ER stress in Evodiamine-induced apoptosis and G2/M arrest of human colorectal carcinoma cells

  Chen, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Colorectal Neoplasms 100%
  • Apoptosis 41%
  • Cyclin B1 30%
  • Proteins 16%
  • Structure-Activity Relationship 13%

• The Roles of Genetic Polymorphisms for Susceptibility and Clinical Outcomes of Colorectal Cancer in Taiwanese Lynch Syndrome Families

  Yeh, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hereditary Nonpolyposis Colorectal Neoplasms 100%
  • DNA Mismatch Repair 57%
  • Colorectal Neoplasms 54%
  • Genetic Polymorphisms 29%
  • Genes 19%

• Oral Health and Interventions for Elderly in Long-Term Care Facilities

  Chang, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • training program 100%
  • caregiver 64%
  • quality good 59%
  • lack 51%
  • health 45%

• Islide - a Global Community E-Learning Online

  Li, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Microscopes 100%
  • Websites 89%
  • Education 88%
  • Medical education 77%
  • E-learning 68%

• A Clinical Correlation Study of DNA Methyltransferases Alterations in Breast Cancer and Evaluation of DNA Methyltransferases as a Therapeutic Target in Cell and Animal Models

  Lin, R.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Tumor Suppressor Genes 95%
  • DNA (Cytosine-5-)-Methyltransferase 1 67%
  • Methyltransferases 40%
  • DNA Methylation 35%

• A Multidisciplinary Study of the Pathophysiology of Blast-Induced Mild Traumatic Brain Injury

  Chiang, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of Genetic and Cellular Factors in Women with Endometriosis(3/3)

  Tzeng, C. & Kao, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Mri Study on Trans-Neuronal Degeneration of the Thalamic Networks after Ischemic Stroke

  Chen, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Thalamus 100%
  • Stroke 96%
  • Thalamic Nuclei 52%
  • Cerebral Infarction 43%
  • Gait 38%

• A Novel Human Blood Plasma-Photosensitizer-Conjugated Nanocomplex for Selectively Killing Colon Cancer via Locally Photodynamic/Photothermal Therapy

  Chuang, E.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Cell Surface Marker 100%
  • Nanomaterial 75%
  • Plasma 74%
  • Growth Factor 70%
  • Nanoparticle 59%

• Developing Therapeutic Mesoporous Silica Nanoparticles for Neurodegenerative Diseases

  Chen, Y.

  1/1/18 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Silicon Dioxide 100%
  • Nanoparticles 78%
  • Neurodegenerative Diseases 42%
  • Blood-Brain Barrier 28%
  • Genetic Therapy 18%

• Using Genome-Wide Linkage Analysis and Next Generation Sequencing Approaches to Identify the Genes Responsible for the Familial Colorectal Cancer Type X(2/3)

  Wang, W.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• A multi-modal investigation of the neurobiology of psychomotor alterations in mania and depression (2/2)

  Martino, M.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Physiological Predictors of Concurrent Cardiovascular Diseases in Bipolar Disorder

  Chen, P.

  8/1/15 → 10/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Bipolar Disorder 100%
  • Cardiovascular Diseases 85%
  • Mortality 22%
  • Psychiatry 21%
  • Hospitalization 21%

• Study the Benefical Effects and Mechanisms of Probiotics and Exercise Intervention Strategies in 6-Ohda Induced Parkinson'S Disease Rat(1/3)

  Huang, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Probiotics 100%
  • Oxidopamine 81%
  • Parkinson Disease 39%
  • Substantia Nigra 25%
  • Gastrointestinal Microbiome 23%

• Study on the Preventive Effect and Mechanism of Germinated Brown Rice and Its Components on Colorectal Cancer

  Shih, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • brown rice 100%
  • colorectal neoplasms 49%
  • carcinogenesis 43%
  • health promotion 34%
  • rice 26%

• Depression Trajectories in Women – A Developmental-ecological approach (GM03)

  Kuo, S.

  8/1/13 → 9/30/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Depression 100%
  • Cohort Studies 34%
  • Postpartum Period 24%
  • Longitudinal Studies 21%
  • Retrospective Studies 17%

• Using Machine Learning Technique to Evaluate the Impact of Curcumin on the Brain-Gut Interaction in Patients with Tuberous Sclerosis Complex Comorbid to Autism Spectrum Disorders(2/3)

  Lo, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Platelets and Platelet-Derived Microparticles for Trojan Horse Cancer Therapy (THCt)

  Burnouf, T. P. R.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • doxorubicin 100%
  • microparticles 83%
  • cancer therapy 31%
  • drug carriers 16%
  • neoplasms 16%

• Mechanisms for Epithelium-Derived Interleukin 33 (Il-33) Up-Regulation and Its Effects on Circulating Fibrocyte Chemotaxis, Proliferation and Differentiation in Patients with Chronic Obstructive Asthma(3/3)

  Kuo, H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• he Effects of the APOE4 Allele on cerebral Structural and Functional Connectivity- A Diffusion Tensor Imaging and Resting-state MRI study

  Chen, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Alleles 100%
  • Apolipoproteins E 93%
  • Brain 47%
  • Short-Term Memory 37%
  • Magnetic Resonance Imaging 31%

• Taiwan R＆D Survey Design and Development ─ Enterprise Questionnaire

  Shia, B.

  4/1/15 → 12/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Survey Design 100%
  • Design and Development 91%
  • Taiwan 62%
  • R and D 58%
  • Technological Development 39%

• Association between Human Endogenous Retrovirus and Cancers Using RNA-Seq Data

  Lee, Y. G.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Endogenous Retroviruses 100%
  • RNA-Seq 28%
  • Genome 22%
  • Neoplasms 21%
  • gag Genes 11%

• Translational studies of Mycobacterium tuberculosis-induced lung and pleural fibrosis

  Lin, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Connective Tissue Growth Factor 100%
  • Mycobacterium tuberculosis 57%
  • Fibroblasts 34%
  • Lung 31%
  • Pulmonary Fibrosis 28%

• Role of Sp-Family in Lung Tumorigenesis

  Chang, W.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Lung 100%
  • Lung Neoplasms 73%
  • Carcinogenesis 61%
  • Doxycycline 61%
  • Neoplasms 43%

• The Functional Role of Pdk1 in Arnt Oncogene-Regulated Tumorigenesis and Tumor Progression

  Chang, W.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neoplasms 100%
  • Enzymes 90%
  • Carcinogenesis 47%
  • Oncogenes 39%
  • Neoplasm Metastasis 38%

• Assessment of Bone Healing Capacity and Osseointegration Potential of Bone Grafting Materials Loaded with Rabbit Mesenchymal Stem Cells Derived from Different Sources: in Vitro and in Vivo Studies

  Feng, S.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • mesenchymal stromal cells 100%
  • bones 71%
  • prostheses 36%
  • dental prosthesis 36%
  • rabbits 30%

• The Roles of Fibronectin Fragments in the Articular Chondrocytes: from Single Nucleotide Polymorphism to Functional Investigation.

  Lee, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • fibronectins 100%
  • chondrocytes 59%
  • cartilage 53%
  • integrins 43%
  • osteoarthritis 23%

• The Role of Muscle Afferents in Lumbar Radiculopathy

  Lin, J.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development a Risk Scoring System for Predicting the Risk of Poststroke Epilepsy to Improve the Quality of Care among Patients with Stroke

  Chien, L.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Epilepsy 100%
  • Stroke 45%
  • Anticonvulsants 24%
  • National Health Programs 20%
  • University Hospitals 15%

• Repurposing of a Positive Allosteric Modulator of M5 Muscarinic Acetylcholine Receptor as a Microtubule-Targeting Agent and Its Application for Treating Pancreatic Ductal Adenocarcinoma

  Hsieh, Y.

  1/1/19 → 6/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 碳60及碳70富勒烯複合奈米材料對皮膚癌之預防潛力研究

  Cho, E.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• (101NP1003) New Drug Development of MPT0E014 for Ischemic Stroke and Dementia (III)

  Hung, K.

  5/1/14 → 4/30/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討臺灣牛樟芝對多型性神經膠質瘤治療的角色、調控基因與開發新穎治療策略

  Lin, J.

  6/1/18 → 12/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Impacts of Particulate Air Pollution on Repair and Abnormal Inflammation in Copd: the Role of Itih4 and the Regeneration Pathways

  Lee, K.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Obstructive Pulmonary Disease 100%
  • inter-alpha-inhibitor 82%
  • Particulate Matter 74%
  • Inflammation 30%
  • human ITIH4 protein 25%

• Investigate Augmented Reality and Repetitive Transcranial Magnetic Stimulation Technology in People with Stroke( II )

  Lai, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Augmented reality 100%
  • Patient rehabilitation 23%

• Identification of Human Viral Micrornas and Its Targets by Using Small RNA Sequencing Data Based on RNA Sequence and Structure Features

  Chang, T.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Forensic Anthropology 14%
  • Databases 13%
  • Viruses 7%
  • Mammals 6%

• 以光譜與光譜影像技術檢測稻米避免遭受黃麴毒素污染之研究

  Chuang, Y.

  5/1/17 → 4/30/18

  Project: A - Government Institution › b - Ministry of Science and Technology