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• b - Ministry of Science and Technology

  The Roles of Micrornas in Endothelin-1 and Hypoxia-Induced Ctgf Production

  Chen, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Endothelin-1 59%
  • Hypoxia 31%
  • Fibrosis 29%
  • Lung 23%

• Role of Hbx and Androgen Receptor in Regulating Senp1/Stemess-Related Properties in Hbv-Related Hcc and Its Clinical Impact

  Huang, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatitis B virus 100%
  • Hepatocellular Carcinoma 65%
  • Hep G2 Cells 23%
  • Hepatitis B 21%
  • Neoplasms 19%

• Evaluating the Biological Characteristics and Clinical Significance of Circulating Tumor Stem Cells in Cancer Progression

  Chen, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Circulating Neoplastic Cells 100%
  • Small Cell Lung Carcinoma 29%
  • Preclinical Drug Evaluations 19%
  • Neoplastic Stem Cells 11%
  • Neoplasms 8%

• Effects of fish oil on alcoholic liver disease in rats based on pathological mechanisms

  Yang, S.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • liver diseases 100%
  • alcohol abuse 83%
  • fish oils 81%
  • liver function 46%
  • rats 39%

• Smokefreebrain: Multidisciplinary Tools for Improving the Efficacy of Public Prevention Measures against Smoking( I )

  Shabbir, S. A.

  5/1/17 → 4/30/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• MTHFR和TYMS基因多形性對口腔癌治療後預後的影響

  Yeh, C.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of the Cerebral Perfusion Changes in Patients with Mild Traumatic Brain Injury Using 3d Bssfp Arterial Spin Labeling Mri

  Liu, H.

  2/1/17 → 10/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Post-Concussion Syndrome 27%
  • Perfusion 26%
  • Traumatic Brain Injury 17%
  • Artifacts 16%
  • Headache Disorders 10%

• Development of Electrochemical Sensors for Candida Albicans Diagnos

  Fan, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Candida 100%
  • Electrochemical sensors 27%
  • Enzymes 14%
  • Amperometric sensors 10%
  • Oxidoreductases 9%

• An in Silico Vaccine Design Method for Allergen Prediction and Ige Epitope Identification Based on Deep Learning Algorithms

  Su, E. C.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Epitopes 100%
  • Allergens 90%
  • Vaccines 63%
  • Immunoglobulin E 48%
  • Deep Learning 43%

• 探討玄米油及油炸玄米油合併運動訓練對於停經後體能表現、腸道菌相、脂肪肝及胰島素阻抗的影響(3/3)

  Chiu, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Self, Consciousness, and Neurophilosophy

  Lane, T. J.

  1/1/14 → 12/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Molecular Model 100%
  • Neurophilosophy 96%
  • Applied Ethics 80%
  • Self-consciousness 68%
  • Philosophy of Science 60%

• Interrelationships between Growth Trajectory, Pubertal Development and Childhood Atopic Diseases/Symptoms in a Longitudinal Cohort Study

  Chen, Y.

  8/1/17 → 10/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Growth 100%
  • Adiposity 95%
  • Puberty 48%
  • Menarche 37%
  • Taiwan 30%

• Pitx2c Modulations on Atrial Fibroblast Activity, Electrical Characteristic, and Myocyte-Fibroblast Interaction: Implications in the Genesis of Atrial Fibrillation

  Kao, Y. & Chen, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fibroblasts 100%
  • Atrial Fibrillation 36%
  • Electrophysiology 26%
  • Angiotensin II 22%
  • Cardiac Myocytes 21%

• Identification of Osteoporosis Susceptibility Gene in Calcium Signaling Pathway

  Hung, K.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Osteoporosis 100%
  • Single Nucleotide Polymorphism 55%
  • Calcium Signaling 33%
  • Genes 22%
  • Genetic Polymorphisms 19%

• The Process Development of Electrospun Silk Fibroin/Sacchachitosan Membranes for Endotoxin Removal Applications

  Yang, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Silk 100%
  • Membranes 47%
  • Biomaterials 45%
  • Purification 42%
  • Molecular weight 42%

• Functional Role of Transcription Factor Sp1 in Brain Neuronal Injury (II)

  Chang, W.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• 設計與合成新穎苯甲醯胺與醯基羥胺取代之雜環化合物分別抑制微小管與組織蛋白去乙醯酉每6為抗癌藥物

  Lai, M.

  11/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Application of Polypropylene Mesh in the Anatomical Correction and Functional Improvement of Pelvic Floor Disorders---Morphological and Functional Exploration

  Yang, J., Yang, S. & Huang, W.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • urethra 100%
  • urinary incontinence 60%
  • surgery 54%
  • polypropylenes 35%
  • fascia 24%

• Applications of Α-Galactosylceramide-Incorporated Liposome as a Targeting Antigen Carrier for Cancer Vaccine Therapy

  Liu, D.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • alpha-galactosylceramide 100%
  • Liposomes 55%
  • Natural Killer T-Cells 16%
  • Active Immunotherapy 12%
  • Antigens 12%

• The Biological Mechanisms of N-3 Polyunsaturated Fatty Acid Treatment in Interferon-Induced Depression

  Huang, S.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Omega-3 Fatty Acids 100%
  • Depression 46%
  • Antidepressive Agents 29%
  • Unsaturated Fatty Acids 20%
  • Inflammation 19%

• 探討SPNS2對於決定個體缺氧耐受性的影響(3/3)

  Yang, C. H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • phenotype 100%
  • therapeutics 58%
  • neurodegenerative diseases 48%
  • pathophysiology 46%
  • arteries 37%

• Studies of the Vegetable Components on Menopausal Obesity and the Associated Mechanisms

  Chen, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • estrogens 100%
  • menopause 92%
  • adipocytes 85%
  • obesity 62%
  • white adipocytes 45%

• 臺美(US)國合計畫－腦傷害的新診斷和新治療之轉譯研究－Sig-1R-Znf179-Sp1路徑在腦傷害之神經保護作用(2/3)

  Chang, W.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • sigma-1 receptor 100%
  • Traumatic Brain Injury 50%
  • Hydrogen Peroxide 31%
  • Neuroprotective Agents 12%
  • Wounds and Injuries 12%

• Expressing Membrane Antibody Reporter in the Islet Cells of Nonobese Diabetic Mice to Noninvasive Assess the Therapeutic Effects of Drugs or Transgenes for Autoimmune Diabetes

  Chuang, K.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • islets of Langerhans 100%
  • mice 95%
  • image analysis 88%
  • pins 80%
  • drugs 47%

• Impacts of Particulate Air Pollution on Repair and Abnormal Inflammation in Copd: the Role of Itih4 and the Regeneration Pathways

  Lee, K.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Obstructive Pulmonary Disease 100%
  • inter-alpha-inhibitor 82%
  • Particulate Matter 74%
  • Inflammation 30%
  • human ITIH4 protein 25%

• The Use of Organometallic Reaction in the Syntheses of Anticancer Agents.( I )

  Liou, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Antineoplastic Agent 100%
  • Chan-Lam Coupling 96%
  • Buchwald-Hartwig Cross Coupling Reaction 79%
  • Ullmann Reaction 76%
  • Alkynylation 75%

• Aldose Reductase and Nf-Kb Signalings in Collagen Receptor Glycoprotein Vi-Mediated Platelet Autophagy: a Regulatory Mechinary of Endogenous Gaba in Anucleate Blood Cells

  Sheu, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Autophagy 100%
  • Blood Platelets 64%
  • Aldehyde Reductase 63%
  • gamma-Aminobutyric Acid 33%
  • convulxin 30%

• Diabetes and the Risk of Parkinson'S Disease&Quot; Investigate the Association between Insulin Resistance and Parkinson'S Disease-Second Term Project

  Hong, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role of Hbx and Androgen Receptor in Regulating Senp1/Stemess-Related Properties in Hbv-Related Hcc and Its Clinical Impact

  Huang, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatitis B virus 100%
  • Hepatocellular Carcinoma 65%
  • Hep G2 Cells 23%
  • Hepatitis B 21%
  • Neoplasms 19%

• Roles of Autophagy and Heme Oxygenases(-1, -2) in Brain Injuries: in Vivo and in Vitro Studies

  Wang, J.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Traumatic Brain Injury 100%
  • Autophagy 97%
  • Brain Injuries 62%
  • heme oxygenase-2 59%
  • Reperfusion 56%

• From Hospital to Community: Longitudinal Changes of Participation in Younger Stroke Survivors(3/3)

  Chang, F.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • stroke 100%
  • rehabilitation 62%
  • participation 57%
  • social support 44%
  • change of activity 18%

• The Role of Sp1-Regulated Neurosteroidogenesis in Glioma Development(2/2)

  Hsu, T.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neurosteroids 100%
  • Glioma 74%
  • Glioblastoma 67%
  • Temozolomide 54%
  • Astrocytes 34%

• Effects of Long-Term Exposure to Indoor Air Pollution and Indoor Air Quality Improvement on Cardiovascular Health in General Population(1/2)

  Chuang, K.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Involvement of Genes Encoding Apoptosis Regulatory Pathway in the Pathogenesis of Hyperglycemia in Acute Ischemic Stroke

  Hsieh, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Multi-Modal Investigation of Self-Consciousness in Major Depressive Disorder(1/3)

  Lane, T. J.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation on the Role of Cytoskeleton Reorientation and Calcium Ion Transportation in Static Magnetic Field Induced Mesenchymal Stem Cells Proliferation

  Huang, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • magnetic fields 100%
  • mesenchymal stromal cells 48%
  • cell proliferation 33%
  • stem cells 28%
  • cells 20%

• The Molecular Biological Mechanism of Fish Oil on Preventing Alcoholic Liver Diseases: The Hepatoprotective Effects of EPA and DHA Based on Lipid Metabolism, Autophagy and Inflammatory Responses

  Yang, S.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • fish oils 100%
  • ethanol 40%
  • rats 36%
  • lipid metabolism 34%
  • liver diseases 30%

• Investigation of B-Cell Activating Factor Expression and Its Role in Radiationenteritis

  Wu, S.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Enteritis 100%
  • Radiation 66%
  • Animal Models 29%
  • Neutralizing Antibodies 24%
  • B-Cell Activating Factor 23%

• "First-in-Class"新穎性抗癌藥物ITCH E3 ubiquitinligase 抑制劑之新藥開發

  Yen, Y.

  7/1/17 → 6/30/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Decellularized Lymph Node Scaffold Vaccine Seeded with Dendritic Cells for Inducing Specific Antitumor Immunity

  Liu, D.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Dendritic Cells 100%
  • Lymph Nodes 61%
  • Immunity 30%
  • Neoplasms 28%
  • Neoplasm Antigens 26%

• Prediction of B-Cell Epitopes Using Propensity Scales and Correspondence Analysis

  Su, E. C.

  8/1/13 → 10/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Epitopes 100%
  • Proteins 46%
  • Bioinformatics 24%
  • Cells 16%
  • Binding sites 15%

• The Development and Clinical Application of a Miniature Transcranial Direct Current Stimulator in Rehabilitation Therapy

  Peng, C.

  11/1/13 → 10/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Patient rehabilitation 100%
  • Animals 34%
  • Health insurance 17%
  • Experiments 12%
  • Medicine 11%

• The Physiological Indicators of Early Cardiac Dysfunction in Patients with Schizophrenia

  Chen, P.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Schizophrenia 100%
  • Psychopathology 22%
  • Echocardiography 18%
  • Psychiatry 16%
  • Cardiovascular Diseases 16%

• 探討發酵米糠之補充對腸道菌生態及腸道黏膜免疫系統之芳香烴受體路徑之影響：以葡聚糖硫酸鈉引致之腸炎小鼠為模式(1/3)

  Yeh, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建立研發用台灣電子病歷資料庫之先期研究－建立研發用台灣電子病歷資料庫之先期研究

  Yang, C.

  4/1/15 → 12/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Rice Bran or Fermented Rice Bran on Modulating Immunosenescence in High- Fat Diet-Induced Obese Aged Mice: Pre- or Post- Menopause and Andropause Mice Model

  Yeh, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Novel Therapeutic Agents for Herceptin Resistance Breast Cancer Cells through Targeting Nicotinic Acetylcholine Receptors

  Lee, C. & Ho, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Trastuzumab 88%
  • Neoplastic Stem Cells 39%
  • Drug Resistance 27%
  • Luciferases 20%

• Role of Sp-Family in Lung Tumorigenesis

  Chang, W.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Lung 100%
  • Lung Neoplasms 73%
  • Carcinogenesis 61%
  • Doxycycline 61%
  • Neoplasms 43%

• Effects of Glutamine Supplementation on T Cell Homeostasis and Inflammatory Response in Inflammatory Bowel Disease

  Yeh, S.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • glutamine 100%
  • inflammatory bowel disease 84%
  • colitis 78%
  • T-lymphocytes 59%
  • ulcerative colitis 57%

• Synthesis and Clinical Investigations of Novel Bismuth (Or Zirconium) Hafnium Oxide for Dental Filling and Radiopacifying Application

  Lin, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • minerals 100%
  • bismuth oxides 82%
  • composite materials 61%
  • hafnium oxides 55%
  • constitution 49%