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• b - Ministry of Science and Technology

  Epigenetic Regulation of Lps-Induced G-Csf Expression in Macrophages

  Chang, S.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Granulocyte Colony-Stimulating Factor 100%
  • Macrophages 19%
  • Epigenomics 17%
  • MicroRNAs 13%
  • Inflammation 11%

• Study on the Mechanism for the Beneficial Effects of Soy Protein on Alcoholic Liver Diseases

  Chen, J.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • soy protein 100%
  • liver diseases 87%
  • alcohol abuse 72%
  • liver 38%
  • peroxisome proliferator-activated receptor alpha 38%

• Targeting and Blockades of Advanced and Metastatic Breast Cancer with Trispecific or Dual Bispecific Antibodies Non-Covalently Bound on Mpegylated Nanocarriers Loaded with Docetaxel and Pictilisib for Synergistic Therapy and Circumventing the Resistance(1/3)

  Sheu, M.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Ultra-Compliant Degradable Hydrogel-Based Bioelectrode Applied for Treating Peripheral Neural Injury

  Huang, W.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Tissue 100%
  • Substrates 49%
  • Moisture 40%
  • Electrodes 35%
  • Signal transduction 34%

• 建構阿茲海默氏症細胞藥物篩選模式：分析小分子藥物488和電漿活化水抑制類澱粉斑塊的形成

  Cheng, C.

  7/1/19 → 2/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Pathophysiology of Macrophage Migration Inhibitory Factor on Electrical and Structural Remodelings in Heart Failure-Induced Atrial Arrhythmogenesis

  Chen, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Heart Failure 100%
  • Atrial Fibrillation 95%
  • Atrial Remodeling 81%
  • Histone Deacetylases 68%
  • Pulmonary Veins 44%

• Investigation of Genetic and Cellular Factors in Women with Endometriosis(II)

  Tzeng, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• In Vivo Early Neuroimage Profiles of Injurious and Protective Responses in Neonatal Hypoxic-Ischemic Models Using 7t Mri(3/3)

  Kao, Y. J.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Lysine-specific histone demethylase 1 抑制劑的研發

  Liou, J.

  2/1/20 → 1/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Association between Maternal Sleep Disturbances and the Health Condition of Their Offspring: a Secondary Data Analysis and a Longitudinal Cohort Study( II )

  Lee, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Bicycle Taillights and Reflective/Led Clothing on Motorists’ Overtaking/Tailgating Behaviours: an On-Field Observation Study

  Pai, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • clothing 100%
  • bicycling 45%
  • automobiles 37%
  • knees 33%
  • lasers 26%

• The Oncogenic Role and Targeted Therapeutic Potential of Alpha 9 Nicotinic Acetylcholine Receptors on Breast Cancers: Emphasizing in Pre-Clinical Assessment of Biphasic Antibody Nano-Drugs in Xenografts(II)(2/3)

  Chang, J.

  8/1/18 → 8/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of the Cytotoxic Mechanism of Photorhabdus Luminescens Pirapl and Pirbpl Toxins by Using Structural and Proteomic Approaches

  Wang, H.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Photorhabdus 100%
  • Insecta 30%
  • Aedes 24%
  • toxin V 19%
  • Xenorhabdus 17%

• Chemical Synthesis of Cancer-Associated Glycoproteins( I )

  Hsieh, Y.

  8/1/20 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Building Smart Medical Information Mart for Neuro Intensive Care (Smart Minic)

  Lin, M.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The molecular pathogenesis of pulmonary fibrosis-Warburg effect在肺纖維化之角色(3/3)

  Chen, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 天然物對鉑類抗藥性膀胱癌之治療潛力及其分子作用機轉探討(2/3)

  Chen, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the Klf10 alters metabolic pathways in genetic-deficient mice and human pancreatic ductal carcinomas

  Chang, H.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • 1-(7-(2-hydroxyethyl)dodecahydro-3a-methyl-1H-benz(e)inden-3-yl)ethanone 100%
  • Metabolic Networks and Pathways 49%
  • Pancreatic Neoplasms 46%
  • Knockout Mice 45%
  • Insulin Resistance 40%

• The Roles of Long Noncoding Rnas Modulation by Toll-Like Receptors Activation in Copd(1/3)

  Wu, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 益生菌PS128對重鬱症患者之生理及憂鬱症狀影響：八周之隨機,雙盲,安慰劑控制試驗

  Chen, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Mechanisms and Therapeutic Strategies of Pd-L1 Expression in Oral Cancers( I )(1/3)

  Lin, H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of a Circulating Tumor Cell-Based Drug Sensitivity Assay for Soft-Tissue Sarcoma( I )

  Lu, L.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sarcoma 100%
  • Doxorubicin 48%
  • Epithelial Cell Adhesion Molecule 14%
  • Circulating Neoplastic Cells 13%
  • Precision Medicine 11%

• 建構定量系統生理基礎藥動模型以評估腸道菌叢對口服藥物代謝影響及協助奈米膠體處方之開發(1/3)

  Hsieh, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Trajectory and Biomarkers for Post-Stroke Cognitive Impairment( II )

  Hu, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討蛋白質去磷酸酶PP4在敗血症中之免疫調控(2/2)

  Yang, F.

  12/1/20 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Depression Trajectories in Women – A Developmental-ecological approach (GM03)

  Kuo, S.

  8/1/13 → 9/30/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Depression 100%
  • Cohort Studies 34%
  • Postpartum Period 24%
  • Longitudinal Studies 21%
  • Retrospective Studies 17%

• Analyses of ADAM9 on Integrin B4 Turnover to Facilitate Prostate Cancer Migration and Invasion

  Sung, S. & Hsieh, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • metastasis 100%
  • integrins 89%
  • neoplasm progression 42%
  • prostatic neoplasms 38%
  • neoplasms 38%

• Systematic Biological Platforms Applying in Endemic Taiwanese Plants

  Lee, M.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Plant Tissue Culture 100%
  • Neuroprotective 67%
  • Ethanol 22%
  • Column Like Crystal 21%
  • Signal Transduction 19%

• Platelets and Platelet-Derived Microparticles for Trojan Horse Cancer Therapy (THCt)(2/3)

  Burnouf, T. P. R.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • doxorubicin 100%
  • microparticles 83%
  • cancer therapy 31%
  • drug carriers 16%
  • neoplasms 16%

• The Effects of Lipoprotein on the Endothelial-To-Mesenchymal Transition Process of Mature Endothelial Cell and Endothelial Progenitor Cells in Vessel Neo-Intimal Formation

  Huang, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • erucylphosphocholine 100%
  • HDL Lipoproteins 96%
  • oxidized low density lipoprotein 25%
  • Dyslipidemias 16%
  • Atherosclerosis 13%

• Cultivation of Young Scholars: Philosophy of Consciousness

  Lane, T. J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Philosophy 100%
  • Taiwan 88%
  • Consciousness 48%
  • Teaching 40%
  • Student Writing 33%

• Investigation of Molecular Mechanisms Governing Cancer Exosomes-Orchestrated Tumor-Host Interaction during Disease Progression.

  Hwang, W.

  2/1/17 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Exosomes 100%
  • Neoplastic Stem Cells 76%
  • Neoplasms 31%
  • Stem Cells 24%
  • Tumor Microenvironment 13%

• Preparation and Application of New Type Matrix for Cell Sheet Engineering Use

  Tseng, H.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Systems engineering 100%
  • Cell culture 86%
  • Membranes 84%
  • Monomers 79%
  • Tissue 57%

• Neural Mechanism of Distractor Induced Attentional Orienting and Suppression

  Hsu, T.

  12/1/15 → 11/30/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• In Vivo Early Neuroimage Profiles of Injurious and Protective Responses in Neonatal Hypoxic-Ischemic Models Using 7t Mri(II)(2/3)

  Kao, Y. J.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 多靶點抗癌藥物之設計與合成(2/2)

  Nepali, K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Antrodia cinnamomea Extract on Fat Accumulation and Energy Expenditure

  Chen, J.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • metabolic syndrome 100%
  • insulin resistance 64%
  • blood pressure 51%
  • adipokines 46%
  • fatty liver 38%

• Self, Consciousness, and Neurophilosophy

  Lane, T. J.

  1/1/14 → 12/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Molecular Model 100%
  • Neurophilosophy 96%
  • Applied Ethics 80%
  • Self-consciousness 68%
  • Philosophy of Science 60%

• Development of Novel Degradable Biomaterial for Dental Hemostatic Sponge Applications

  Lin, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • teeth 100%
  • surgery 91%
  • hemostasis 60%
  • biocompatibility 52%
  • animal experimentation 52%

• Study the Therapeutic Effects and Novel Molecular Mechanisms of Resveratrol in Human Osteosarcoma: the Treatment of Metastatic Cancer

  Chien, M.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Mechanistic Action of DDX3 in Colorectal Tumor Progression

  Lee, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • beta Catenin 100%
  • Catenins 46%
  • Drug Resistance 45%
  • Neoplasms 43%
  • Colorectal Neoplasms 39%

• Application of Diffusion Tensor Imaging to Study the White Matter Integrity and Coherence in Resting Electroencephalography

  Shiu, R. & Wang, H.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Electroencephalography 100%
  • Brain 42%
  • Magnetic resonance 40%
  • Imaging techniques 39%
  • Fibers 26%

• The Impacts of Sirtuin Related Genes and Aging Related Factors on the Risk of Early-Onset Ischemic Stroke

  Hsieh, F.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sirtuins 100%
  • Stroke 34%
  • Genes 20%
  • MicroRNAs 14%
  • telomerase RNA 8%

• Explore the Prevalence of Sarcopenia among Elderly and the Effect of Health Promotion Program

  Hung, Y. & Tseng, I. J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sarcopenia 100%
  • Elderly 40%
  • Taiwan 29%
  • Health Promotion 19%
  • Exercise 19%

• 從食品風險暴露之角度探討非營養性甜味劑對女性生殖狀況之影響-非營養性甜味劑對子宮收縮及生殖細胞之影響效應及相關機轉探討(1/3)

  Hsia, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies on the Molecular Mechanism of Thrombin-Induced Connective Tissue Growth Factor (CTGF) Expression in Lung Fibroblasts

  Lin, C.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Connective Tissue Growth Factor 100%
  • Thrombin 61%
  • Fibroblasts 24%
  • MAP Kinase Kinase Kinase 5 20%
  • Transcription Factor AP-1 18%

• Role of Organic Anion Transporter in Renal Tubular Injury---A Gateway to Hurt

  Wu, M.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Renal Insufficiency 100%
  • Organic Anion Transporters 52%
  • Kidney 45%
  • Single Nucleotide Polymorphism 40%
  • Messenger RNA 27%

• Therapeutic Evaluation Etanercept, a Tumor Necrosis Factor Antagonist, in Experimental Heatstroke

  Chang, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • heat stroke 100%
  • tumor necrosis factors 42%
  • therapeutics 32%
  • death 31%
  • animal models 18%

• The Effect of Blood Sugar Regulation and Molecular Mechanism by White Potato Extract

  Li, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • blood glucose 100%
  • sweet potatoes 75%
  • diabetes 59%
  • noninsulin-dependent diabetes mellitus 53%
  • insulin resistance 51%

• 國際產學聯盟計畫II

  Lin, C.

  9/1/18 → 11/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology