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• b - Ministry of Science and Technology

  A High Density and Nano-Sized ReRAM Crossbar Array Using Copper Chemical Displacement and Nanotip Array Techniques (I)

  Wu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • random access memory 100%
  • diodes 21%
  • copper 13%
  • schedules 11%
  • nitrides 8%

• 提升臺灣生殖醫學在生育保存領域之國際競爭力及影響力 (2/3)

  Tzeng, C.

  1/1/15 → 12/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular Epidemiology, Related Risk Factors and Phylogenetic Analysis of Epilepsy-Causing Neurotoxocariasis or Neurocysticercosis in the Kingdom of Eswatini, Africa

  Fan, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Evaluation of Platelet-Rich Plasma Combined Nanogel for Angiogenesis and Bone Remodeling Application in Sinus Augmentation Model

  Tseng, C.

  1/1/12 → 12/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • sinuses 100%
  • bones 50%
  • angiogenesis 36%
  • bone substitutes 23%
  • rabbits 19%

• Applications of Α-Galactosylceramide-Incorporated Liposome as a Targeting Antigen Carrier for Cancer Vaccine Therapy

  Liu, D.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • alpha-galactosylceramide 100%
  • Liposomes 55%
  • Natural Killer T-Cells 16%
  • Active Immunotherapy 12%
  • Antigens 12%

• Degradation of Nitrogen-Containing PPCPs: Kinetic Study, Application, and Balancing the Toxicity of N-DBP and Intermediates through Bioassay

  Chang, E.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • PPCP 100%
  • chlorination 35%
  • ozonation 26%
  • nitrogen 24%
  • byproduct 21%

• New Brain Cortical Electrical Stimulation Technology for the Neurorehabilitation Therapy of Bladder Dysfunction in the Parkinson’S Disease Animal Model

  Peng, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Determinant Clinical Parameters for Shifting Prescriptions among Nifedipine+Quercetin; Atorvastatin, and Captopril+Quercetin in Treating the Hypertension of Chronic Kidney Disease

  Chen, K.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Quercetin 100%
  • Doxorubicin 88%
  • Chronic Renal Insufficiency 52%
  • Antihypertensive Agents 35%
  • Atorvastatin 23%

• 結核菌感染臨床免疫組庫建立:探勘免疫球蛋白於結核菌感染之保護機制與臨床轉譯應用(2/3)

  Tsai, I.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Wearable Device Evaluation for Medication Management in Patients Taking Sleep Medicine via Cloud Platform Development( I )

  Li, Y., Jian, W. & Lee, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sleep 100%
  • Wearable technology 35%
  • Health 28%
  • Education 19%
  • Oximeters 11%

• Prevalence of Metabolic Dysregulation and Effects of Adjunctive Metformin on Metabolic Profiles in Clozapine-Treated Schizophrenic Patients

  Chen, C. & Lu, M.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Metformin 100%
  • Clozapine 93%
  • Fasting 31%
  • Waist Circumference 20%
  • Body Weight 18%

• Analyze Exhaled Gas of COPD Patients ( II )

  Shih, C.

  5/1/15 → 4/30/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Electronic Nose 100%
  • Chronic Obstructive Pulmonary Disease 82%
  • Gases 26%
  • Smart Materials 25%
  • Hand 23%

• Process Characterization and Optimization of Human Serum Albumin Nanoparticles as Drug/Gene Carrier Systems

  Sheu, M.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Nanoparticle 100%
  • Drug 82%
  • Silencing RNA 57%
  • Biodegradability 46%
  • Safety 38%

• Estrogen Affects the Colon-Urethra Crosstalk via Spinal Kalirin/PSD-95-NR2B-Dependent NR2B Phosphorylation in Rats(2/3)

  Lin, T.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • urethra 100%
  • colon 58%
  • estrogens 48%
  • mustard oil 48%
  • pain 27%

• The Role of Activating Transcription Factor 3 on Metabolic Syndrome in Fructose-Fed Mice

  Fang, T.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Activating Transcription Factor 3 100%
  • Fructose 62%
  • Metabolic Syndrome 36%
  • Oxidative Stress 28%
  • Inflammation 23%

• The Severity Model of Brain Damage: Examining the Blood-Brain Early Injurious and Protective Biomarker Panels That Relate to the Susceptibility and Tolerance Responses of Hypoxic Ischemia( I )

  Huang, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Association between Maternal Sleep Disturbances and the Health Condition of Their Offspring: a Secondary Data Analysis and a Longitudinal Cohort Study( II )

  Lee, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Translational Investigation of the Role of Myc/Pd-L1/Akt Axis as a Therapeutic Target for Treating Glioblastoma Multiforme

  Lin, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Psychophysiological Effects of Lactobacillus Plantarum Ps128 in Patients with Major Depressive Disorder: a Pilot Study of 8-Week Open Trial

  Chen, C.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Lactobacillus plantarum 100%
  • Probiotics 77%
  • Gastrointestinal Microbiome 71%
  • Inflammation 53%
  • Permeability 46%

• Bio-Inspired and Digital Design (Mgi+Ai) Driven Silk Protein Fibers in Design, Synthesis, Fabrication for Translational Researches(2/4)

  Yang, J.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Involvement of Il-21-Regulated Circulating Fibrocyte Activation in Chronic Obstructive Asthma( II )

  Hsieh, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 青少年期慢性睡眠剝奪對認知、情緒與壓力調適功能之影響:動物模式與人類世代之整合研究-青少年期慢性睡眠剝奪對認知、情緒與壓力調適功能之影響:健康青少年族群之觀察追蹤與介入研究(2/3)

  Lee, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Evolution of Active Intracranial Atherosclerotic Plaques after Stenting - an Observation Using Mr High Resolution Vessel Wall Imaging

  Chen, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Atherosclerotic Plaques 100%
  • Arteries 71%
  • Endothelial Cells 70%
  • Antioxidants 35%
  • Anti-Inflammatory Agents 35%

• Exploration of the Pharmacological Mechanisms of Hai-Fu-Rong as an Anti-Restenosis Remedy

  Wu, C.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Vascular Smooth Muscle 100%
  • Smooth Muscle Myocytes 89%
  • Cell Movement 83%
  • Coronary Balloon Angioplasty 83%
  • Pharmacology 67%

• Study on the Mechanism of Cross-Talk between Ahr and Autophagy, and Autophagy---Associated Physiological or Pathological Phenomenon on Vascular and Airway Systems (I)

  Li, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Aryl Hydrocarbon Receptors 100%
  • Autophagy 88%
  • Benzo(a)pyrene 17%
  • Fibrosis 15%
  • Endothelial Cells 15%

• 探討芳香烴受體(AhR)改變血管內皮細胞功能之新角色：經由表觀基因或後轉譯修飾(細胞週期蛋白/內皮細胞一氧化氮合成酉每)的調控與白蘆黎醇/史達汀臨床治療及應用(2/3)

  Juan, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Imapct of Oxidative Stress on the Pathogenesis of COPD---An Ivestigation into Its Relationship with Abnormal Inflammation, Dna Instability, Epigenetics and Cell Metabolism

  Lee, K.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Obstructive Pulmonary Disease 100%
  • Oxidative Stress 47%
  • Inflammation 33%
  • Blood Cells 26%
  • Glucocorticoids 21%

• Development a Tissue-Like Block by Novel Porous Calcium Phosphate Combined Dental Pulp Stem Cells and Platelets Rich Fibrin for Bone Regeneration in Large Bony Defect

  Lee, S. & Yang, J.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Calcium phosphate 100%
  • Stem cells 80%
  • Pulp 61%
  • Bone 54%
  • Platelets 43%

• The Study of Apoptosis, Inflammation, Autophagy and Organ Functions in Rat Liver Following Hemorrhagic Shock and Protective Mechanism of Ligustrazine.

  Chen, R. & Wang, Y.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Reperfusion Injury 100%
  • tetramethylpyrazine 93%
  • Liver 85%
  • Autophagy 69%
  • Hemorrhagic Shock 61%

• Pulmonary Effects of Chorioamnionitis and Postnatal Hyperoxia in Rat Offspring

  Chen, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chorioamnionitis 100%
  • Hyperoxia 72%
  • Bronchopulmonary Dysplasia 58%
  • Renin-Angiotensin System 48%
  • Lung Injury 37%

• Epigenetic Modulation of Lipid by Cyclopeptide Nanotube on Oral Delivery(2/2)

  Liaw, J.

  8/1/16 → 12/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • nanotubes 100%
  • delivery 41%
  • genes 41%
  • lipids 34%
  • drugs 26%

• CAAT/enhancer binding protein beta訊息路徑參與thrombin誘導人類肺部上皮細胞IL-8/CXCL8表現之研究(3/3)

  Chen, B.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Identification a Novel Circadian Clock-Mediated Cell Dividing in Hepatocyte: Mechanistic Exploration for Physiological and Pathological Functions in Liver(I)

  Chao, H.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Antibody Repertoire in Mycobacterium Tuberculosis Infection: Investigate Functional Immunoglobulins in Tb Infection and Translational Applications

  Tsai, I.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研究BTK/HER2信號通路在HER2陽性乳腺癌生物特性角色: 調控T細胞的效應及逆轉賀癌平抗藥性的分子機制(2/3)

  Chao, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 益生菌PS128對重鬱症患者之生理及憂鬱症狀影響：八周之隨機,雙盲,安慰劑控制試驗

  Chen, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌細胞α9尼古丁受體作為新穎靶向RNA奈米藥物與T細胞療法之臨床轉譯研究-探討α9尼古丁受體基因表現在乳癌病人血液循環腫瘤細胞/游離DNA於乳癌治療的應用(1/3)

  Tzeng, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Neurotrophic/Neuroprotective Role of Gip in Cellular and Rodent Models of Mild Traumatic Brain Injury.( I )

  Lin, J.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Peptides 62%
  • Glucose 62%
  • Incretins 25%
  • Glucagon-Like Peptide 1 23%
  • Neuroprotection 20%

• The Role and Molecular Mechanism of Urotensin II in Renal Disease: Focus on Tubular Injury and Renal Fibrosis

  Hsu, Y., Chen, T. & Chen, C.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • urotensin II 100%
  • Kidney 27%
  • Fibrosis 11%
  • Wounds and Injuries 10%
  • Renal Insufficiency 8%

• Novel Activities of Gamma-Aminobutyric Acid-Mediated Regulation of Platelet Activation, Apoptosis, and Autophagy: the Non-Genomic Functions of Nf-Kappab Signal in Anucleated Cells

  Sheu, J.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • gamma-Aminobutyric Acid 100%
  • Blood Platelets 65%
  • Platelet Activation 27%
  • Mitochondrial DNA 26%
  • Autophagy 20%

• Evaluation of Clinical Feasibility of Quantitative MR Perfusion Imaging and Its Calibration

  Tseng, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Magnetic Resonance Imaging 100%
  • Calibration 93%
  • Cerebrovascular Circulation 87%
  • Gray Matter 45%
  • Perfusion 45%

• Sleep Disturbances in Methadone Maintenance Treatment---A Case-Control Study

  Lee, H. & Kang, J.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Methadone 100%
  • Sleep 45%
  • Mental Disorders 23%
  • Case-Control Studies 23%
  • Central Sleep Apnea 20%

• 可攜式急性腎臟損傷 (AKI)及顯影劑腎病變(CIN)尿液微型核醣核酸的非侵入式檢測系統之發展及開發單一化學藥物治療AKI及CIN所造成之腎損傷(1/3)

  Lin, H.

  5/1/17 → 4/30/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Association between Maternal Sleep Disturbances and the Health Condition of Their Offspring: a Secondary Data Analysis and a Longitudinal Cohort Study( I )

  Lee, H.

  8/1/16 → 10/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Mothers 100%
  • Sleep Deprivation 92%
  • Child 51%
  • Sleep 50%
  • Child Health 38%

• Study on the Mechanism of Cross-Talk between Ahr and Autophagy, and Autophagy-Associated Physiological or Pathological Phenomenon on Vascular and Airway Systems( III )

  Li, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Carotid Atherosclerosis and Cardiac Function Measured by Ultrasonography in Bipolar Mania and Their Relevent Clinical Factors(3/3)

  Tsai, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討多環芳香烴受體缺陷重啟多能細胞特性之新穎路徑與應用

  Li, C.

  8/1/20 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of Novel Genetic Mutations for Antibiotic Resistance, Intracellularly Upregulated Salmonella Genes Within Host Cells, and the Mechanisms of Yqic-Induced Host Innate Immunity for Combating Salmonella Infection

  Fang, S.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Salmonella 100%
  • antibiotic resistance 37%
  • ciprofloxacin 34%
  • point mutation 33%
  • genes 26%

• Urinary Total Arsenic Levels, Arsenic Methylation Capacity, Plasma Selenium Concentrations and Genetic Polymorphisms of Glutathione Peroxidase and Selenoprotein and Prostate Cancer

  Hsueh, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • arsenic 100%
  • prostatic neoplasms 78%
  • selenium 48%
  • selenoproteins 39%
  • glutathione peroxidase 27%

• The Carotid Atherosclerosis and Cardiac Function Measured by Ultrasonography in Bipolar Mania and Their Relevent Clinical Factors

  Tsai, S.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology