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  Study the Interactive Functions of Decoy Receptor 3 and Galectin-3 in Keratinocytes and Macrophages

  Lin, W.

  10/1/14 → 9/30/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• TMU103-AE1-B03

  Lin, C.

  10/1/14 → 9/30/15

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• Differential Machinery of Pluripotency Regulation in Stem Cells in Embryonic Stage and Somatic Cancers and Its Clinical Implications in Human Diseases---Crosstalk among Niche Growth Factor/Cytokine Signaling, Extracellular Matrix, and Epigenetic Netw (I)

  Huang, Y.

  10/1/14 → 9/30/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• 103年度國民體適能檢測站設置實施計畫

  Kan, N.

  9/24/14 → 3/30/15

  Project: A - Government Institution › d - Ministry of Education

• 103年度「103-104年國民長期照護需要調查訪視控管作業」

  Huang, Y.

  9/11/14 → 6/30/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 103年度「含中藥材創意商品開發」

  Hou, W.

  9/1/14 → 4/30/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 北區高階生醫產業聚落及產業規劃-台灣遠距健康產業聚落發展先導計畫

  Yen, Y. & Chen, R.

  9/1/14 → 8/31/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

• Long-term follow-up study of health behaviors among adolescent cohort.

  Chiou, H., Chen, P., Chen, Y., Chang, H., Yang, S. & Chen, Y. C.

  9/1/14 → 12/31/14

  Project: A - Government Institution › c - Ministry of Health and Welfare

• Development of 3d-Printing Dynamic Orthosis-For Hemiplegic Lower Limbs( I )

  Chen, S.

  9/1/14 → 11/30/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Novel Strategies to Target Long-Lived Plasma Cells for Treating Hemophilia a Inhibitors

  Liu, C.

  9/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Phase I, First-In-Human, Dose-Seeking Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of Orally Administered MPT0E028 in Subjects with Advanced Solid Malignancies without Standard Treatment (I)

  Liou, J.

  9/1/14 → 9/30/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Application of resilience engineering in emergent health care services

  蘇, 清., Chuang, S., 馬, 漢. & 蔡, 哲.

  8/7/14 → 8/6/15

  Project: A - Government Institution › a - National Health Research Institutes

• Valproate治療腦外傷病人的臨床研究

  Chang, C., Chiang, Y., Liao, K., Yang, S., Wu, C. & Chen, K.

  8/7/14 → 8/6/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 國人口腔健康監測調查企劃案

  Tsai, H.

  8/4/14 → 12/31/14

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 山藥儲藏性蛋白質功能性月生月太之延緩衰老功能評估與機制探討(2/3)

  Hou, W.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Study the Correlation between Serum Markers of Oxidative Stress, Inflammation, and Endocrine-Disrupting Chemicals (Edcs) and Their Impact on the Menstrual Cycle and Reproductive Hormone in Taiwanese Women.

  Hsu, M.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• An Investigation of the Effects of Tea Component on the Inhibition of Leukocyte Nicotinic Acetylcholine Receptor Expression on Breast Cancer Patients

  Tu, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Oncolytic Measles Virus for the Treatment of Breast Adenocarcinoma

  Lin, L. T.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Evaluation of the Mechanism of Post-Traumatic Immunosuppression---The Role of TLR4 Trafficking and microRNA

  Lin, J. A.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• 鐵質誘發巨噬細胞活化與遷移對胰島素耐受性的影響

  Chang, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌是目前世界上女性癌症病患中為數最多的癌症之ㄧ。腺病毒蛋白type 5 E1A (E1A)和許多抗腫瘤作用有關，曾於多種癌症如乳癌、卵巢癌及頭頸癌之病患進行臨床基因治療試驗。許多的研究指出E1A具有多項抗腫瘤的功能，包括抑制腫瘤的發生、增加腫瘤細胞對於化療藥物的感受性以及減少腫瘤轉移的現象。腫瘤的轉移對於癌症患者的死亡率有極大的影響當然也包括了乳癌的患者。E1A於抑制腫瘤發展的過程中具有多重生物學上的意義，這也促使我們想要釐清E1A抑制癌症的機制。因此，我們對於了解E1A抑制癌症轉移相關的分子機制感到有興趣，並期望藉以作為未來改進乳癌病人臨床試驗的基石。我們初步的實驗結果顯示，E1A可以有效的抑制Glucose-regulated protein 78 (GRP78)這種已被廣泛報導和腫瘤惡化及轉移相關的蛋白的表現。 提出此研究計劃之目的在於詳細探討E1A所造成的抑制癌轉移作用中，GRP78所扮演的生物功能及其調控的機轉。為了達到此目的，我們將著重於E1A如何調控GRP78表現並進而展現對乳癌轉移的抑制作用。以下為此項研究計畫的四大主要目標： 目標一：探討GRP78在E1A所抑制之癌細胞移行及侵入作用中所扮演的角色 目標二：研究E1A抑制GRP78表現之分子機轉 目標三：於動物模式中驗證GRP78的表現對於E1A抗腫瘤作用的影響 目標四：探討GRP78及其相關分子的表現在乳癌病人的臨床重要性 完成以上的主要目標能夠幫助我們對於E1A之抗腫瘤轉移作用建立更加詳細的分子訊息傳遞機制。另外，藉由此研究計畫的新發現也許可以對未來發展癌症治療上提供更多具有潛力的標的物。

  Wang, W.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Relationships of One-Carbon Cycle Pathways with Psychopathology and Metabolic Abnormalities in Patients with Schizophrenia and Potential Intervention Strategy with 5-Methyltetrahydrofolate and Vitamin B12

  Chen, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Glutamine on the Inflammatory Response and Tissue Injury in a Hindlimb Ischemic Reperfusion Mice Model

  Yeh, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Explore of Toll-Like Receptors Associated miRNA Expression in Ischemic Stroke Patients (II)

  Wu, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Association between Lipid, Glucose Related Genes and Prognosis of Intra- and Extra-Cranial Stenosis in Stroke Patients

  Chiou, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Different Sources of n-3 Fatty Acids on Bone Loss, Body Fat and Inflammatory Markers in Osteoporotic Condition with Diabetes

  Chiu, W. & Fong, T.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of a Program of Mind-Body Interventions on Psychological Resilience, Vagal Tone, Emotional States, and Outcomes of Heart Failure

  Tsai, P.

  8/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Study of the Trismus Condition of Patients with Head and Neck Cancer Who Have Undergone Concomitant Chemoradiotherapy and the Preventive Effect of Oral Rehabilitation on Trismus

  Jeng, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Association Study of Genetic Polymorphisms of Toll-Like Receptors on Ischemic Stroke (II)

  Chiou, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Explore the Molecular Mechanisms and Application of microRNA-16 in In Acute Kidney Injury

  Chen, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Emerging Mechanisms of Omega-3 Fatty Acids in Depression---The Effects of EPA and DHA on Chronic Stress, Neurogenesis and Neuroinflammation

  Huang, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of ADAM 17 in Hypoxia-Induced CTGF Expression and Pulmonary Fibrosis (II)

  Chen, B.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Series of Studies Analyzing Exercise Behavior and Exploring the Effects of Interventions among Pre-Diabetes, Type 1, and Type 2 Diabetes

  Jeng, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Effects of Metabolic Abnormalities on Cognitive Function in Schizophrenic Patients

  Lu, M.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Translational Studies of Mycobacterium tuberculosis-Induced Lung and Pleural Fibrosis

  Lin, C.

  8/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• 粒狀空氣污染物所產生的氧化壓力對慢性阻塞性肺疾病患者的泛素-蛋白酉每平衡系統之影響:探討氧化壓力，異常發炎以及蛋白質氧化之關係

  Chuang, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Process Development of Electrospun Silk Fibroin/Sacchachitosan Membranes for Endotoxin Removal Applications

  Yang, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Application and Mechanism of Novel Fluoro-Rutaecarpine on Inhibition of Inflammation Induced Endomt

  Lin, C.

  8/1/14 → 12/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Cultivation of Young Scholars: Philosophy of Consciousness

  Lane, T. J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Evaluation of the Long-Term Effects of Interpersonal and Social Rhythm Therapy on Sleep and Social Functioning in Patients with Bipolar Disorder

  Chung, M.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role of miR-21 in Regulating TET I-Hydroxymethylcytosine and Chemotherapeutic Response in Colorectal Cancer (I)

  Yang, P.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Infant Feeding Information in the Internet and How the Information Influences the Infant Feeding Behavior

  Chen, Y. C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Novel Roles of Aldose Reductase (AR) in Collagen GPVI- and Thrombin PAR4-Mediated Platelet Activation and Apoptosis---Regulatory Machinery of Arf-AR Signaling in Anucleate Cells

  Sheu, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Inhibitory Effect and Mechanism of Bioactivated Rice on Colorectal Carcinogenesis

  Shih, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Roles of Central OX2R Activities in the Pathophysiology of Hypertension in SHR

  Hwang, L.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Determined the Role and the Mechanims of GRP94 in Mediating the Progression and Therapeutic Responses of HCC

  Huang, M.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Unraveling the Impact of Deletion of Androgen Receptor on Brain Trauma

  Yang, L.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Synaptic Plasticity by Nogo-1 Receptor Overexpression and Exendin-4 Administration on Behavioral and Electrophysiological Recovery after Mild Traumatic Brain Injury (III)

  Tsai, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study and Implementation of Patient Privacy Protection under the Framework for Electronic Medical Records Exchange in Taiwan

  Liu, C.

  8/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effect of RRM2 in Tumor Metastasis and Chemotherapy Response of Colorectal Cancer Patients with Different APC and K-Ras Status

  Cheng, Y.

  8/1/14 → 7/31/16

  Project: B - Project of TMU › i - Other (Funded by TMU)