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  探討在慢性腎臟疾病中經由抑制內皮素轉化?調節前列腺素E2受體和自體吞噬作用的治療潛力之機轉(2/3)

  Chiu, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 樹突細胞PD-L1/PD-L2失調在COPD 異常發炎的角色及機制探討(3/3)

  Lee, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 轉錄因子Sp1在癌細胞抗藥性所扮演角色-HDACs/Sp1-microRNA-106b~25軸在膠質母細胞瘤抗藥性扮演的角色(3/3)

  Chen, R.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討新型冠狀病毒棘狀蛋白S1誘導心臟電生理及結構性重塑之病理機制：治療新型冠狀肺炎引發心臟損傷之新契機

  Kao, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討ACSL1/FASN訊號軸調控脂質代謝重編程在泌尿道上皮癌化學/免疫治療抗性和轉移所扮演的角色與新穎治療策略的開發

  Wu, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• P-選擇素調控具靶向多功能陰離子奈米載體包覆雙嘧達莫或白蛋白具有遠紅外光可觸發的熱療溫度/藥物釋放的聯合療法做為臨床應用(3/3)

  Chuang, E.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討TEAD4調控粒線體活性及引發攝護腺癌症的機制(1/5)

  Kung, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 膠淋巴系統於混合型失智症之角色(2/2)

  Hu, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 甲基乙二醛經ChREBP/SREBP1造成腎小管脂毒性進而調控PGC1/SIRT3導致電子傳遞鏈缺陷之糖尿腎病進展-探討水飛薊素(Silybin)合併Metformin之逆轉潛能

  Chen, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新穎性DYRK1A抑制劑於阿茲海默症之機轉探討(3/3)

  HuangFu, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用輸卵管上皮類器官培養技術開發卵巢癌早期偵測之表基因生物標記(2/3)

  Lai, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探究巨噬細胞移動抑制因子於肺纖維化疾病中的免疫病理角色

  Chen, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 自體免疫心肌炎引起心室心律不整及鈣離子調控失衡、粒線體異常與NLRP3/MIF發炎體訊息路徑活化之致病機轉及治療策略探討(1/3)

  Chen, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Beta 3腎上腺素信號傳導對心律異常的發生：從心室心肌細胞中心臟代謝，氧化壓力和鈣離子恆定的見解

  Hsieh, M.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 電子菸的心房電生理影響動物模式 – 對電子菸致心房心律失常潛在威脅的研究

  Lin, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 混合中位數及平均數之統合分析方法探討--應用於pre-post之研究設計

  Chen, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以尿?雙磷酸葡萄糖醛酸基轉移?2B7 (UGT2B7) 開發新穎三陰性乳癌標靶治療策略(2/3)

  Lee, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發天然物及其衍生物應用於阿茲海默症之治療(1/3)

  Pan, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探索蝦急性肝胰腺壞死病毒素 PirAvp 與 PirBvp 之活化機制與中和策略(2/3)

  Wang, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 真實世界數據應用於風險評估設定醫療照護模式以提昇住院照護品質研究-方法建立與導入實施(1/2)

  Chen, T.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 隨機模型於精準健康科學之應用-應用隨機模式於不適健康照護之精準健康科學評估(3/3)

  Yen, M.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 結合精密儀器與資料庫和對接技術的天然物研究一一植物代謝體的應用及問題解決(1/3)

  Lee, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• RAB3C對大腸直腸癌之抗藥性與腫瘤免疫反應影響之探討(2/3)

  Chen, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 創新電漿活化水製備表面增強拉曼散射活性基材(3/3)

  Liu, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 血中的纖維細胞在嚴重氣喘患者扮演第二型細胞激素嶄新的細胞來源其臨床相關性與調控機制(2/3)

  Kuo, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Metformin抑制TRPA1與P2X3受器所引發的呼吸反射及過度敏感之機制探討

  Lin, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 台灣中醫醫療利用情形、長期趨勢及其影響因素：一項多樣本的大型研究

  Liao, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 攝護腺癌經PGC1α/SIRT3/ETC Complexes調節粒線體動態及代謝重整促進腫瘤細胞存活及侵襲性之探討-以SIRT3調節劑減緩化學抗藥性之策略評估

  Peng, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討非營養性甜味劑對生殖系統之影響及可能作用機轉:從青春期到懷孕期-婦女攝取非營養性甜味劑對懷孕狀況之影響(2/3)

  Hsieh, R.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Local Circadian Clock Regulation of Fluid Barriers to the Brain

  Myung, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Choroid Plexus as a Hub of Immune-Clock Interaction That Connects the Body to the Brain in Prematurity (2/3)

  Myung, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以深度學習來預測細胞表面蛋白並應用單細胞轉錄體之功能分類鑑別

  Chen, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 「智慧心肺訓練系統」用於中風患者之可行性研究

  Lin, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Lepidium Meyenii (Maca) Extract Supplementation on Immune Function, Inflammatory Responses, Oxidative Stress after Strenuous Endurance Exercise

  Yang, M.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 添加抗菌藥物的抗扭轉生物塗層在3D列印金屬植體之應用(1/2)

  Lin, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研究慢性阻塞性肺病中調控發炎老化的新機轉: miR-1, miR-133及let-7c之負調控導致過度活化gp130-IL-6信號傳遞路徑(1/3)

  Su, B.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發混合型機器學習之代謝物滯留時間預測模型用於辨識液相層析串聯質譜儀實驗之代謝物(2/2)

  Wang, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新穎癌幹細胞侵犯腳治療標靶之整合性蛋白質體、基因體、小分子與功能篩選：聚焦細胞表面AMFR於侵犯性消化道癌症治療標的(2/3)

  Tsai, K. K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 護理人員減效出席之系列研究(1/2)

  Jeng, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Legal Reform for Improving Vaccine Procurement and Preparedness Framework in Taiwan

  Ho, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Cortisol Awakening Response and Stress in Female Shifting Monthly Nurses

  Chang, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 間質幹細胞在低氧微環境促進神經內分泌型前列腺癌的作用與新穎治療策略(1/3)

  Hsieh, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新穎性USP24抑制劑於膠質母細胞瘤抗藥性之機轉探討

  Wang, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 甜蜜的戰爭二部曲:含糖飲料與網路的誘惑

  Chen, Y. C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以CRISPR/Cas9基因編輯平台發展MYC/BCL2/BCL6作為人類B細胞淋巴癌標靶精準治療模式

  Chen, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 標題：謹慎設計抗胃癌藥物：結構簡化方法、骨架躍遷策略以及對二氧化矽負載的質子酸/路易斯酸催化的多組分反應以產生關鍵中間體的詳盡探索

  Nepali, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Long-Term Impact of Discharge Destinations and Transitional Care Uses on Health and Medical Utilization for High-Risk Discharged Older Adults (3/3)

  Chi, M.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 解析LINC00704/miR-122 axis於癌幹細胞化及抗藥性產生分子機制以作為口腔癌精準診療監測生物標記(1/3)

  Tsai, L.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 後生元和益生菌透過抑制炎症和調節免疫力減輕新生小鼠高氧誘導的肺損傷

  Chen, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 辛伐他汀抗腎細胞癌的作用，經由抑制代謝重編程從mTOR、PPAR到RhoA(3/3)

  Juan, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology