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  空氣污染引發易感受族群呼吸道症狀與預後之相關性研究

  Chuang, K.

  1/1/13 → 12/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

• 含碘-鉑之奈米載體做為肺癌診斷之治療試藥之開發

  Tseng, C.

  1/1/13 → 12/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

• TMU101-AE1-B14

  Chang, W.

  1/1/13 → 12/31/14

  Project: B - Project of TMU › i - Other (Funded by TMU)

• TMU101-AE1-B13

  Chang, H.

  1/1/13 → 12/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Study of Multi-Organ Damage in Heatstroke-Induced Rats

  Wang, Y.

  12/1/12 → 11/30/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Potential of Capsaicin against Advanced Glycation Endproducts Formation

  Wu, C.

  12/1/12 → 11/30/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Sustainability Literacy Survey in Taiwan

  Chang, W.

  12/1/12 → 12/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Preclinical and Clinical Trial Evaluation for an in vitro Diagnostic Kit of Endometriosis (I)

  Yang, W.

  12/1/12 → 2/28/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• 同步輻射X光合成奈米銀修飾複合材料顆粒及其應用

  Lin, C.

  11/1/12 → 10/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

• The Regulation of Pml Degradation by Sentrin-Specific Protease 2

  Chang, C.

  11/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Biodegradable Poly(Ε-Caprolactone)/Calcium Phosphate Ceramic Composite Screw for Osteofixation Device in Craninoxaxillofical Surgery

  Yang, K.

  11/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Innate Immune Modulator---Molecular Characterization of Bupleurum kaoi Polysaccharide Fraction and Assessment of Its Immunomodulatory and Antiviral Effects

  Lin, L. T.

  11/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• 小客車路口闖紅燈、加速行為: 以kernel logit 模型估計行人倒數計時器之影響

  Pai, C.

  11/1/12 → 7/31/14

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• Expressing Membrane Antibody Reporter in the Islet Cells of Nonobese Diabetic Mice to Noninvasive Image the Disease Progression of Autoimmune Diabetes and the Therapeutic Effects of Drugs or Transgenes

  Chuang, K.

  11/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role and Use of Blood Protein Fractions in Translational Therapy

  Burnouf, T. P. R.

  11/1/12 → 10/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

• 原住民幸福調查-調查指標訂定

  Lyu, S.

  10/25/12 → 12/25/13

  Project: A - Government Institution › f - Other (Funded by Government)

• 2012台北市立聯合醫院(仁愛院區)員工體適能檢測及促進策略擬訂計畫

  Kan, N.

  10/22/12 → 12/31/12

  Project: A - Government Institution › f - Other (Funded by Government)

• Niche Signaling Networks in Self-Renewal and Migration of Pluripotent Germline Stem Cells and Its Implication for Germline Differentiation in Human Pluripotent Stem Cells (II)

  Huang, Y.

  10/1/12 → 9/30/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• 臺北市大安區無菸公園執行成效問卷調查計畫

  Yeh, C.

  10/1/12 → 10/31/12

  Project: A - Government Institution › f - Other (Funded by Government)

• 成人預防保健服務尿酸、血液常規項目效益分析計畫

  Bai, C.

  9/28/12 → 12/15/12

  Project: A - Government Institution › c - Ministry of Health and Welfare

• Evaluation on prevention for metabolic syndrome and diabetes mellitus through lifestyle modification intervention in pre-diabetic subjects (100-104)

  Chiou, H., Bai, C., Tang, C., Yang, S., Su, C., Liou, T., Wang, S., Chen, J., Hsieh, A. & Huang, C.

  9/13/12 → 9/12/13

  Project: A - Government Institution › c - Ministry of Health and Welfare

• Power-Assisted Rehabilitation Device with Electrical Stimulation---Brige from Engineering to Clinical Trials

  Chen, S.

  9/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• 慢性肝病在台灣是一個極具挑戰性的臨床議題。肝纖維化的多重病原性是造成病患死亡 率增加的原因，而且肝纖維化往往會發展成肝癌。我們最近利用國民營養調查資料庫 (NAHSIT 2005-2008)分析國人血中鐵營養值標與代謝症候群的相關性.在全人口的分析 中，我們發現校正了血清發炎指標以及飲食的營養指標後, serum ferritin (鐵蛋白質) 高於最大三等分位的族群，得到代謝性症候群的危險對比值超過 1.6 倍. 目前並不清楚 過量的鐵蛋白質為何與代謝症候群的發生率有關。肝臟為重要的儲鐵器官但是臨床研究 也顯示過量的鐵質沉積與肝纖維化及肝癌有極大的相關性。血清中鐵蛋白質為反映體內 儲存鐵的生化質標。但是,發炎因子也會造成血清中鐵蛋白質的異常增加。證據顯示發炎 因子可以調控鐵蛋白質的基因表現量。但是慢性發炎如何造成鐵蛋白質代謝異常(組職 內沉積及釋放)? 血清中的鐵蛋白質又有何生理功能? 隨著國人代謝症候群及脂肪肝發生率的年輕化,這次研究的主題是以老鼠初代星狀肝細 胞來分析鐵蛋白質對內質網壓力機轉與肝纖維化的影響: 相關研究的主要目標為: 1. 釐清鐵蛋白質(serum ferritin)過量是否會造成星狀細胞內質網壓力增加與活化? 2. 何種鐵質(ferric, ferrous, ferritin, Apoferritin)較易增加內質網壓力? 3. 找出何種內質網壓力的轉錄因子 (ATF6,ATF4, XBP1 and CHOP)受到鐵質調控? 4. 分析鐵質誘導的內質網壓力機轉與肝臟纖維化的營響

  Chang, J.

  9/1/12 → 8/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Teledermatology Solutions Though Mobile Phone

  Li, Y.

  9/1/12 → 8/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Roles of Tgf-B Signal and Inflammatory Cells in Mfs Patients and the Possible Correlation between Marfan Syndrome and Autoimmune Disease

  Chiu, H.

  9/1/12 → 12/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• 生命期營養單張-更年期營養單張

  Yang, S.

  8/20/12 → 12/31/12

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 行政院衛生署所屬醫院101年度滿意度調查評估採購案

  Kuo, N.

  8/6/12 → 11/15/12

  Project: A - Government Institution › f - Other (Funded by Government)

• 環境正義視野下的流域治理：石門水庫集水區上游泰雅族部落永續發展策略之行動研究－石門水庫集水區整治之 政策分析：一個環境治理的觀點(III)

  Lin, Y.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies on the Anti-Islet Hypertrophy and Anti-Osteoporosis Constituents from Formosan Fern

  Hsu, F.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• 「智慧生活跨領域基礎課程與服務學習課程推廣計畫」-可攜式行動保健裝置暨個案健康評估管理資料庫服務學習課群擴散計畫

  Chiu, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › d - Ministry of Education

• Molecular Therpary and Mechanism Study in Spinal Cord Injury

  Hung, K.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Integration of Research on Novel Antibacterial Mini-Implant

  Lin, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study of Anti-Αlpha-Enolase I Antibodies on Cancers and Their Potential Applications

  Yang, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Therapeutic Evaluation Etanercept, a Tumor Necrosis Factor Antagonist, in Experimental Heatstroke

  Chang, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• 依療法律與醫學倫理

  Ho, J.

  8/1/12 → 1/31/13

  Project: A - Government Institution › d - Ministry of Education

• Advanced Research for a Decision Model of Emergency Patient Intelligent Dispatch

  Hsu, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Design and Evaluation of a Novel Drug-Containing Ceramic Hydrogel for the Healing of Alveolar Bone Defect

  Lee, S.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• The First Randomized Controlled Clinical Trial for Computerized Decision Support System (II)

  Li, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Avoidable Hospitalizations and Primary Care Manpower in a Universal Health Insurance System: a 15-Year Trend Analysis

  Huang, K.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Exercise Training on Sleep Disturbances, Anxiety, and Depression among Newly Diagnosed Elderly Lung Cancer Patients

  Lin, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Targeting Hif-1α by Zebularine for the Treatment of Colorectal Cancers

  Yang, P.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• 睡眠困擾是癌症病人最常主訴的問題之一。患有睡眠困擾之癌症病人經常同時伴隨 疲憊、憂鬱等現象發生，形成症狀群集，影響生活品質。雖然目前對於癌症病人睡眠障 礙之量性研究已多有著墨，然而對於癌症病人經歷睡眠障礙之主觀經驗之瞭解，仍相當 有限。瞭解病人經歷睡眠障礙之主觀經驗，將有助於未來睡眠評估工具之修訂。另外， 在評估癌症病人睡眠品質時，若能以簡單工具評估，會更具效率及助益。阿森斯失眠量 表(Athens Insomnia Scale, AIS) 是一個簡單的8 題問卷，廣為使用在一般失眠的病人， 在癌症病人使用上，尚未有豐富的實證資料，若能建立其在癌症病人的信效度，將可作 為一簡單篩檢癌症病人失眠的工具。 睡眠遵行日夜節律規則，日夜節律又需要光作為矯正的線索，光在癌症病人睡眠的 角色，尚未有研究證實，過去研究顯示癌症病人睡眠品質不佳與生物節律有關係。光是 重要日夜節律的線索，光療法透過褪黑激素調節，調整日夜節律週期，可能可以改善睡 眠品質。另外，由於，睡眠障礙、憂鬱、疲憊經常形成一症狀群集，光療法於改善睡眠 障礙之同時，是否亦同時改善憂鬱、疲憊及生活品質。目前，光療法在癌症病人的運用 上，付之闕如，故建立光療法於癌症病人的有效性值得探究。 本研究為三年期研究計畫，目的包括有：1.瞭解癌症個案對於睡眠困擾的主觀經驗 （第一年）。2.建立阿森斯失眠量表中文版的信效度、敏感性、特異性（第一年）。3.瞭 解癌症病人光暴露與生物節率、睡眠障礙的關係（第二年）。4.瞭解光療法對於改善癌 症病人睡眠障礙及相關症狀群集、及生活品質之成效；以及瞭解光療法影響褪黑激素之 程度（第三年）。 本研究擬以癌症住院及門診病人為對象，研究工具包括基本資料、匹茲堡睡眠品質 問卷、阿森斯失眠問卷，簡明疲憊量表，貝克憂鬱量表度、SF-36 生活品質量表、腕動 力器等。資料處理分析方式包括：內容分析、描述性統計、t 檢定、皮爾森相關、GEE (generalized estimating equations)等。 本研究之結果將可瞭解光暴露與生物節率與睡眠障礙之間的關係，並可進一步瞭解 光療法作為改善癌症病人睡眠障礙之護理措施之成效，以期，最終能藉由改善癌症病人 之睡眠品質提昇病人之生活品質。

  Lin, C.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Dissected the Role of Alpha-7 Nicotinic Receptor in the Prognosis and Clinical Therapy on Gastric Cancers

  Chang, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Epigenetic Regulation of Lps-Induced G-Csf Expression in Macrophages

  Chang, S.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Enhancement of Immuno-Modulatory Capacity by Shear Stress in Mesenchymal Stem Cells

  Ho, J.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Oral Health and Interventions for Elderly in Long-Term Care Facilities

  Chang, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Relationship between Sleep and Memory in Alzheimer Animal

  Hu, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Depression Trajectories in Women – a Developmental-Ecological Approach (Gm03)

  Kuo, S.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Analysis the Role of Satellite Cell during Denervation Induced Muscular Atrophy and a Trail of Transplantation of Adipocyte Derived Myogenic Stem Cells.

  Chang, H.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Hypoxia in Transcriptomics and Epigenomics Regulation during Pre-Implantation Embryo Development

  Tzeng, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology