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• 牙周致病菌加劇腹主動脈瘤生成的機制與開發標靶治療的可行性研究(1/3)

  Lin, F.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 血中的纖維細胞在嚴重氣喘患者扮演第二型細胞激素嶄新的細胞來源其臨床相關性與調控機制(2/3)

  Kuo, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 樹突細胞PD-L1/PD-L2失調在COPD 異常發炎的角色及機制探討(3/3)

  Lee, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 副甲狀腺素藉由SFRP2導致動靜脈廔管病變之惡化 – 預防動靜脈廔管不成熟之新治療標的 (第二年延續計畫)

  Liu, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研究第14 腫瘤壞死因子（TNFSF14）對粥狀動脈硬化進展、血管內皮功能及心血管疾病之影響– 從基礎到臨床

  Hsu, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以質譜食品質體學探討加工過程與食品組成分對於動物性與植物性食品中糖化終產物生成之影響以及開發降低食品中糖化終產物之加工方法

  Hung, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以代謝工程建立紫色桿菌素胞外生產系統與其連續式醱酵製程開發(1/3)

  Lin, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研究BTK/HER2信號通路在HER2陽性乳腺癌生物特性角色: 調控T細胞的效應及逆轉賀癌平抗藥性的分子機制(3/3)

  Chao, T.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 輕度腦外傷後白質損傷及修復: 新穎磁振定量影像和基因生物標記研究(1/3)

  Li, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以真實世界資料建構懷孕處方適當性平台 : 輔以種子藥師培育，降低不適當用藥(1/3)

  Yang, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 藉由活化JNK路徑以治療Osimertinib抗藥性肺腺癌的策略研究

  Yao, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 醫療人員及國際學生之新冠肺炎問卷調查

  Chiu, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 應用二苯乙烯苷刺激人類牙髓幹細胞衍生的外泌體於再生醫學之臨床前研究(1/3)

  Lee, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討引導受體與配體之間的cis-弱化互動對脊髓運動神經迴路形成的影響(1/3)

  Kao, T.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 標靶整合素αvβ3-FAK訊號網絡的膽管癌診療策略開發-標靶膽管癌整合素αvβ3訊號網絡的新型診療性奈米微脂體DL-N2之研究(1/3)

  Lin, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 多功能奈米載體攜帶化療藥物併用HDAC抑制劑於三陰性乳癌之應用

  Chiu, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 釐清神經類固醇的代謝在神經膠質瘤的抗藥性中扮演的角色(3/3)

  Hsu, T.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 轉錄因子Sp1在癌細胞抗藥性所扮演角色-HDACs/Sp1-microRNA-106b~25軸在膠質母細胞瘤抗藥性扮演的角色(3/3)

  Chen, R.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討非選擇性與選擇性組蛋白去乙醯酶抑制劑與免疫檢查點抑制劑合併治療之效用及其機轉(2/3)

  Huang, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 雙極症患者單核球和巨噬細胞活化與血管粥狀化的關聯性: 頸動脈超音波的個案對照研究(1/3)

  Tsai, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以腸肝腦軸探討魚油對於長期攝取酒精大鼠腦損傷之影響：由脂質代謝及胰島素抗性、免疫發炎反應以及氧化壓力等途徑探討EPA和DHA的腦部保護作用(1/3)

  Yang, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研究介白素-1受體拮抗劑(IL1RN)在胰臟癌的功能(1/3)

  Tsai, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新穎癌幹細胞侵犯腳治療標靶之整合性蛋白質體、基因體、小分子與功能篩選：聚焦細胞表面AMFR於侵犯性消化道癌症治療標的(2/3)

  Tsai, K. K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建構定量系統生理基礎藥動模型以評估腸道菌叢對口服藥物代謝影響及協助奈米膠體處方之開發(2/3)

  Hsieh, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以循環腫瘤細胞擴增系統預測非小細胞肺癌治療反應

  Chen, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 運用深度學習演算法分析多國資料庫以預防特發性妊娠疾病之臨床預測和致病反應途徑研發(1/3)

  Su, E. C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研究PKLR促進前列腺癌神經內分泌分化之代謝途徑及其治療角色(2/3)

  Liu, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 不同脂肪酸組成的植物油對停經後肌肉萎縮之影響-以肌腸軸、胰島素阻抗及粒線體功能觀點進行探討

  Chiu, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 母親食安風險認知對孩童體內實際鉛、鎘、砷暴露之影響(2/3)

  Chien, L.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探索蝦急性肝胰腺壞死病毒素 PirAvp 與 PirBvp 之活化機制與中和策略(2/3)

  Wang, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Using Deep Learning to Improve Cerebrovascular Reserve Measurement from Baseline Mri

  Chen, D. C. & Li, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以經顱交流電刺激治療思覺失調症的隨機對照試驗(1/3)

  Lu, M.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 腦創傷老人中長期多重功能變化以及整體功能評估工具在輕度腦創傷老人之檢驗(2/3)

  Lin, M.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 脂質薑黃素顆粒(SLCP)在體內對mTOR訊息路徑的作用–尋求以疾病機制為基礎對結節性硬化症(TSC)癲癇的治療策略(1/3)

  Lee, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發混合型機器學習之代謝物滯留時間預測模型用於辨識液相層析串聯質譜儀實驗之代謝物(2/2)

  Wang, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建構虛擬斑馬魚系統以研析化合物毒性(1/3)

  Tung, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 甲狀腺荷爾蒙調控腸上皮細胞屏障與通透性的角色探討-針對甲狀腺影響腸道作用之路徑研究

  Lin, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展三功能抗體(EGFR/CD3/mPEG)修飾之聚乙二醇-免疫增敏奈米藥物以主動標靶毒殺大腸癌並同時強化體內 T 細胞於腫瘤微環境抗癌功效之創新協同療法-發展新型聚乙二醇-免疫增敏奈米藥物載體以毒殺大腸癌並強化腫瘤區域T細胞之抗癌功效(2/3)

  Liu, D.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用人工智慧建立兒童腦中風預測模型並估計醫療開支以實現永續發展

  Iqbal, U.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討在慢性腎臟疾病中經由抑制內皮素轉化?調節前列腺素E2受體和自體吞噬作用的治療潛力之機轉(2/3)

  Chiu, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 從食品風險暴露之角度探討非營養性甜味劑對女性生殖狀況之影響-非營養性甜味劑對子宮收縮及生殖細胞之影響效應及相關機轉探討(2/3)

  Hsia, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 中風後視覺依賴與早期多重感覺平衡復健介入之成效探討(3/3)

  Lee, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發天然物及其衍生物應用於阿茲海默症之治療(1/3)

  Pan, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 血清轉位蛋白TSPO作為診斷標記及神經元損傷指標合併發炎反應對認知功能機制探討(1/3)

  Bai, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 思覺失調症者的聽覺異常與腦中神經傳導物質的關聯(1/2)

  Lin, I.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討KH-Type切割調控蛋白在腎細胞癌惡性進程中所扮演的角色(2/3)

  Chien, M.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• A multi-modal investigation of the neurobiology of psychomotor alterations in mania and depression (2/2)

  Martino, M.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 纖維肌痛症患者之微生物叢相-腸-腦軸線異常與神經發炎的研究

  Kang, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 打造即時「同理心溫度計」協助醫病互動(1/2)

  Li, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討運動結合益生菌補充策略對巴金森氏症改善效果與可能機轉(2/3)

  Huang, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology