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• 發展可標靶樹突細胞之mPEG-PLGA/PLGA-PEG-PLGA混和水膠體的奈米顆粒癌症疫苗用於癌症免疫療法(3/3)

  Ho, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 艾克曼嗜黏蛋白菌和電漿活化水對硫酸葡聚醣鈉誘導的潰瘍性結腸炎的保護作用：從微生物代謝產物和蛋白質以及細胞外泌體中的小分子核醣核酸觀點出發

  Chang, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• (教學實踐) 內科學三點突破教學發展計畫

  Chang, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › d - Ministry of Education

• 轉錄因子Sp1在癌細胞抗藥性所扮演角色-HDACs/Sp1-microRNA-106b~25軸在膠質母細胞瘤抗藥性扮演的角色(3/3)

  Chen, R.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Building a Comprehensive Model of Individual Variations in Responsiveness to Electrical Brain Stimulation (2/4)

  Tseng, P.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 間質幹細胞在低氧微環境促進神經內分泌型前列腺癌的作用與新穎治療策略(1/3)

  Hsieh, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• BSP相似重複序列家族蛋白在草綠色鏈球菌所引起的感染性心內膜炎中細菌逃避免疫攻擊及生物膜形成所扮演的角色及機制探討(3/3)

  Jung, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 紫杉醇調控血小板活化、細胞凋亡和自我吞噬之分子機轉探討:體內及體外試驗(2/3)

  Lu, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 賽滅寧對於imiquimod誘發乾癬樣皮膚炎小鼠發炎反應及CD4+ T細胞平衡之影響

  Hou, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以深度學習技術增進從靜息態磁振造影評估腦血管反應性

  Chen, D. C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 評估糖稅課徵政策對肥胖相關疾病負擔之影響：微觀模擬預測模型之研究(2/2)

  Lo, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研究MSN在大腸直腸癌中對病程進展的調控機制和其治療角色

  Wei, P.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討牙周病對牛皮癬之影響與治療用藥策略性之研究

  Lee, A.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 認知功能缺損長者的平衡控制與動作策略：三維動作分析以及穿戴式雙重任務訓練裝置之開發及其於居家介入之成效(第二、三期)(2/2)

  Kuan, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 不同脂肪酸組成的植物油對停經後肌肉萎縮之影響-以肌腸軸、胰島素阻抗及粒線體功能觀點進行探討

  Chiu, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 多功能奈米載體攜帶化療藥物併用HDAC抑制劑於三陰性乳癌之應用

  Chiu, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 標靶整合素αvβ3-FAK訊號網絡的膽管癌診療策略開發-標靶膽管癌整合素αvβ3訊號網絡的新型診療性奈米微脂體DL-N2之研究(1/3)

  Lin, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 麻醉護理專業證照及進階制度之臨床能力架構與評量—客觀結構式臨床測驗(OSCE)與可信賴專業活動(EPA)等工具之建構與驗證研究(2/2)

  Chen, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討海馬迴神經與膠質細胞交互作用於腦創傷後長期認知後遺症之機制作為藥物治療之契機

  Wang, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建立中風後失智疾病風險預測模式提升中風後照顧品質(3/3)

  Chien, L.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以IgA1 O-聯結醣基為標靶開發IgA腎病變之診斷試劑重塑臨床評估之準則(2/3)

  Lee, Y.

  8/1/20 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用輸卵管上皮類器官培養技術開發卵巢癌早期偵測之表基因生物標記(2/3)

  Lai, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 混合中位數及平均數之統合分析方法探討--應用於pre-post之研究設計

  Chen, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以小分子甲殼素奈米粒子建構水生魚類的核酸運輸平台

  Cheng, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 甲基乙二醛經ChREBP/SREBP1造成腎小管脂毒性進而調控PGC1/SIRT3導致電子傳遞鏈缺陷之糖尿腎病進展-探討水飛薊素(Silybin)合併Metformin之逆轉潛能

  Chen, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Long-Term Impact of Discharge Destinations and Transitional Care Uses on Health and Medical Utilization for High-Risk Discharged Older Adults (3/3)

  Chi, M.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 滑世代幼兒期親子睡眠與晝夜節律追蹤研究-整合智慧型資料探討3C產品使用與孕產期相關因子影響效應(3/3)

  Chen, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌細胞α9尼古丁受體作為新穎靶向RNA奈米藥物與T細胞療法之臨床轉譯研究-探討α9尼古丁受體基因表現在乳癌病人血液循環腫瘤細胞/游離DNA於乳癌治療的應用(2/3)

  Tzeng, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 電子菸的心房電生理影響動物模式 – 對電子菸致心房心律失常潛在威脅的研究

  Lin, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 結合深度學習及數據非依賴採集質譜法以偵測膜蛋白體突變與癌症新生抗原(1/3)

  Han, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 進展性胰臟癌新穎增進免疫療法的治療策略與生物指標-節拍式化學治療增進基質硬化性胰臟癌免疫監督與免疫檢查點阻斷療法: 聚焦於腫瘤基質與髓源性抑制細胞(3/3)

  Tsai, K. K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討EZH2在嚴重氣喘中媒介纖維化蛋白表現及呼吸道纖維化之機轉(2/3)

  Lin, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討ACSL1/FASN訊號軸調控脂質代謝重編程在泌尿道上皮癌化學/免疫治療抗性和轉移所扮演的角色與新穎治療策略的開發

  Wu, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 在慢性阻塞性氣喘中double cortin like kinase 1 (DCLK1)在thrombin誘導IL-8/CXCL8表現及氣道發炎的病理角色之研究(2/3)

  Chen, B.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 運用人工智慧協助臨床胸部X光肋骨骨折偵測

  Chiu, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌細胞α9尼古丁受體作為新穎靶向RNA奈米藥物與T細胞療法之臨床轉譯研究-開發抗α9尼古丁受體/抗CD3雙功能抗體以一步驟建構可高效標靶毒殺乳癌腫瘤之武裝型T細胞免疫療法(2/3)

  Chuang, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 標靶整合素αvβ3-FAK訊號網絡的膽管癌診療策略開發-基於整合素αvβ3和CEACAM6的訊號網絡建立膽管癌患者的診斷生物標記與治療標靶之臨床連結(1/3)

  Whang-Peng, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 有機/無機混成奈米複合材料發展智慧型藥物傳輸系統以治療p53失效腫瘤之探討與評估

  Cho, E.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討非營養性甜味劑對生殖系統之影響及可能作用機轉:從青春期到懷孕期-婦女攝取非營養性甜味劑對懷孕狀況之影響(2/3)

  Hsieh, R.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 血中的纖維細胞在嚴重氣喘患者扮演第二型細胞激素嶄新的細胞來源其臨床相關性與調控機制(2/3)

  Kuo, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 慢性阻塞性肺病轉譯動物疾病模式中尼古丁誘發心室心律不整發生的機轉見解和全新的治療策略(1/2)

  Chan, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 同步脈波調變式驅動生物活體靜脈紅光雷射整合微觀臨床血液透析血管鹵素鈣鈦礦成像系統

  Liou, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建立國人電腦斷層脊椎椎體結構強度之預測模型

  Chen, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以動態功能性腦連結來探討胼胝體切開術後對雙側與單側半腦網路的影響以及與神經心理功能表現關聯性

  Peng, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 子宮內膜間質肉瘤之分子機轉及生物標記研究

  Kao, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討低氧微環境腫瘤外泌體與發炎細胞激素IL-6於B型肝炎病毒誘導肝癌表現多能性幹細胞基因OCT4與TKI抗藥性之調控機制與其臨床意義

  Huang, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討發酵米糠之補充對腸道菌生態及腸道黏膜免疫系統之芳香烴受體路徑之影響：以葡聚糖硫酸鈉引致之腸炎小鼠為模式(2/3)

  Yeh, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討甜味受體在調控血糖衡定所扮演的角色(1/3)

  Wu, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展具有靶向及溶解血栓功能的奈米藥物治療平台(2/2)

  Mi, F.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以質譜食品質體學探討加工過程與食品組成分對於動物性與植物性食品中糖化終產物生成之影響以及開發降低食品中糖化終產物之加工方法

  Hung, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology