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• 新穎性選擇性HDAC抑制劑之抗癌藥物開發與藥理機轉探討(3/3)

  Pan, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 社區民眾血管硬化程度分布，以及血管鈣化硬化粥狀硬化與代謝發炎相關生物標記及其基因多型性關連性研究(3/3)

  Bai, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 攝護腺癌之精準代謝治療(3/3)

  Kung, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 天然物對鉑類抗藥性膀胱癌之治療潛力及其分子作用機轉探討(2/3)

  Chen, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 轉錄因子Sp1在癌細胞抗藥性所扮演角色-HDACs/Sp1-microRNA-106b~25軸在膠質母細胞瘤抗藥性扮演的角色(2/3)

  Chen, R.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討在慢性腎臟疾病中經由抑制內皮素轉化酶調節前列腺素E2受體和自體吞噬作用的治療潛力之機轉(1/3)

  Lin, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 絲氨酸/蘇氨酸蛋白激酶(SIK3)參與乳癌致癌過程的分子機制探討

  Chen, L.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討腎臟細胞暴露於塑膠微粒和塑膠奈米中誘發自體吞噬作用和增加SREBPs並引起血管內皮細胞滲漏作用之機制(1/3)

  Chiu, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討KH-Type切割調控蛋白在腎細胞癌惡性進程中所扮演的角色(1/3)

  Chien, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 滑世代幼兒期親子睡眠與晝夜節律追蹤研究-整合智慧型資料探討3C產品使用與孕產期相關因子影響效應(2/3)

  Chen, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討第一型內皮細胞分子與上皮細胞生長因子受體之相互調控在非小細胞肺癌進程之角色(3/3)

  Chien, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Bicalutamide經Sirt3/p53引發腎膈細胞電子傳遞鏈複合體I缺陷而致細胞凋亡機制的探討-輔以Idebenone及MitoTempo提升氧化磷酸化系統及調節粒線體動態之治療策略評估

  Peng, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用多模式小動物進階磁振造影技術定量膠質母細胞瘤之研究(2/2)

  Liu, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 多體學量測平台探討微環境動態變化：以調控脂肪細胞可塑性為例

  Chang, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 整合臨床血液透析高分辨率生物活體脈衝光驅動鹵素鈣鈦礦成像於微觀血管彈性研究與紅外線照射系統

  Liou, J.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 人類牙髓幹細胞輔以二苯乙烯?衍生物促進組織再生之精準化醫療策略(2/2)

  Lee, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 早幼粒細胞白血病鋅指蛋白(PLZF)對腦部發育的多重功能之探討(3/3)

  Lee, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以體外循環腫瘤細胞擴增系統發展兒童神經腫瘤精準醫療策略

  Liu, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展用於促進中風患者雙側踝關節協調控制與下肢功能表現之評估與復健系統-II(2/2)

  Lin, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研究肺氣腫發展中調控細胞老化的分子機轉: 前胸腺素-HuR-SIRT1路徑

  Su, B.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 母親食安風險認知對孩童體內實際鉛、鎘、砷暴露之影響(1/3)

  Chien, L.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討ARE結合蛋白質與選擇性聚腺甘酸化作用在人類大腸直腸癌上所扮演的角色(3/3)

  Liang, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 噬菌體展現技術製備之辨識蛇毒蛋白的雞源單鏈抗體之分析與人源化研究

  Yang, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討NPC2基因調控肝癌細胞內游離型膽固醇恆定在sorafenib抗藥性之角色(2/3)

  Liao, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 組織胺甲基化轉換酵素(HNMT)輔助臨床醫師鑑別乳癌病患作為Herceptin療效評估之新穎分子標記(2/3)

  Ho, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 基於深度學習與機器學習混合分析多體學數據於癌症精準醫學治療之應用評估(1/2)

  Chang, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討EZH2在嚴重氣喘中媒介纖維化蛋白表現及呼吸道纖維化之機轉(1/3)

  Lin, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 胃腸科相關癌症之差異蛋白質體與致病機轉之研究

  Lee, J.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討脊髓損傷中NLRP3發炎體路徑所扮演的角色

  Lin, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the Effect of Dietary Tryptophan Supplementation Strategies in Parkinson’S Disease Progression and Tryptophan Metabolism with Plag6 Knockin Mice

  Huang, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 從食安風險暴露之角度探討非營養性甜味劑對女性生殖狀況之影響-非營養甜味劑暴露之評估及其對脂肪組織的影響(1/3)

  Chen, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用長期血液循環腫瘤DNA探討基因變異與前列腺癌復發風險與抗藥性以發展個人化醫療標記之研究

  Shao, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 轉錄因子Sp1在癌細胞抗藥性所扮演角色-花生四烯酸的代謝在Sp1對神經膠質瘤與肺癌抗藥性的陰陽作用中扮演的角色(2/3)

  Chang, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討PCTK1激?蛋白在大腸直腸癌發展的角色及其調控機制(延續計畫)(3/3)

  Wei, P.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 第三型分泌粒蛋白在代謝症候群之轉譯研究

  Wu, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 抑制NLRP3發炎體- 糖尿病心肌病變的治療新策略

  Lee, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 合成可雙重抑制組織蛋白去乙醯酶6與熱休克蛋白90，並同時調節PD-L1之雜環類抗癌化合物

  Lai, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Integrated Study of Clinical, Molecular Analysis, Mr-Based Radiogenomic, and Preclinical Trials for Precision Treatment of Atypical Teratoid/Rhabdoid Tumor (Atrt) in Children(2/3)

  Wong, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• (教學實踐) 系統性強化高齡藥事照護之進階藥學實習評估

  Chang, E. H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › d - Ministry of Education

• 住院急性胰臟炎使用鴉片類處方藥物病人之持續性使用分析

  Chen, S. H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 有機金屬催化反應於合成化學和藥物化學之抗癌表觀遺傳學抑制劑研究(2/2)

  Liou, J.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• P-選擇素調控具靶向多功能陰離子奈米載體包覆雙嘧達莫或白蛋白具有遠紅外光可觸發的熱療溫度/藥物釋放的聯合療法做為臨床應用(2/3)

  Chuang, E.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 助孕酮受器在葉酸抑制腫瘤細胞生長及轉移所扮演的角色(3/3)

  Lee, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以社會壓力模型大鼠研究鋰鹽心臟保護作用之分子機轉(2/2)

  Chen, P.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 植基於圖技術的雲癌症精準醫學之機器學習模組

  Lee, Y. G.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 肺纖維化之分子病理機制探討-IL-21調控的循環纖維球活化參與在慢性阻塞性氣喘之角色(3/3)

  Lin, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討神經發炎中星狀膠質細胞內CEBPD活化的小分子核糖核酸及其對血管新生的影響(II)(2/2)

  Ko, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 在國際健康功能與身心障礙分類系統的架構下，探討蛋白質補充合併運動訓練對急慢性機構衰弱老人改善肌少症指數及身體活動功能之成效(2/3)

  Liou, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 股市變動與心理健康：醫院急診入院的實證研究

  Hsiao, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討新穎表觀遺傳調控作為缺氧性口腔癌標靶-探討LncRNA-KDM4 axis在缺氧性口腔癌之角色(2/3)

  Kung, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology