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Effect of Pacemaker Current Inhibitor (Ivabradine) on Sinoatrial Node Function and Pulmonary Vein Arrhythmogenesis

Lin, Y.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

包載9α-型尼古丁乙醯膽鹼受體抑制劑之標靶性微脂體劑型設計與開發

Sheu, M.

8/1/127/31/13

Project: B - Project of TMUh - Other (Funded by TMU)

The Novel Development of Continuous Bladder Volume Measurement System

Chen, S.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Phosphoproteomic Study on Mechanisms of Silymarin Modulating Fungicide Induced Sperm Dysfunction

Wu, T.

8/1/1210/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Improvement of Cryopreservative Effect of Natural Killer Cell by Increasing Membrane Rigidity Using Static Magnetic Field

Huang, H.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

探討鎮靜藥物dexmedetomidine保護腦血管免於缺血-再灌流傷害之機轉: 細胞和動物研究

Wu, G.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Simultaneous Delivery of an Antisense Oligonucleotide and a Chemotherapeutic Agent by a Her2-Targeted Liposomal System

Chiu, S.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Application of Clinical Anti-Arthralgia Formulas of Traditional Chinese Medicine to Arthritis

Wang, C.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Effects of Glutamine Supplementation on T Cell Homeostasis and Inflammatory Response in Inflammatory Bowel Disease

Yeh, S.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

The Role of Microrna Let-7g in Cytosolic Ca2+ Regulation and Cox-2 Gene Expression

Chang, W.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Targeting Hif-1α by Zebularine for the Treatment of Colorectal Cancers

Yang, P.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

The Neurotrophic/Neuroprotective Role of Gip in Cellular and Rodent Models of Mild Traumatic Brain Injury.( I )

Lin, J.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

A Study of the Influence on Medical University Students$ Beliefs in Mathematics by Liberal Arts Courses in Mathematics Culture

Ying, J.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Effects of Maternal Depressive Symptomatology on Pregnancy Outcomes and Newborn Development---How Is Paternal Psychopathology Involved?

Chen, Y.

8/1/129/30/13

Project: A - Government Institutionb - Ministry of Science and Technology

The Roles of Genetic Polymorphisms for Susceptibility and Clinical Outcomes of Colorectal Cancer in Taiwanese Lynch Syndrome Families

Yeh, C.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Association between Lipid, Glucose Related Genes and Prognosis of Intra- and Extra-Cranial Stenosis in Stroke Patients

Chiou, H.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Epigenetic Regulation of Lps-Induced G-Csf Expression in Macrophages

Chang, S.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

The Roles of Micrornas in Endothelin-1 and Hypoxia-Induced Ctgf Production

Chen, Y.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Effects of Fish Oil on Alcoholic Liver Disease in Rats Based on Pathological Mechanisms

Yang, S.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

A Translational Study to Confirm the Roles of Gata-Dna Binding Proteins in Bone Healing

Chen, R.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Motorcyclist Behavioural Patterns to Pedestrian Green Signal Countdown Device (Pgscd): a Mixed Logit Analysis

Pai, C.

8/1/129/30/13

Project: A - Government Institutionb - Ministry of Science and Technology

Role of Er Stress in Evodiamine-Induced Apoptosis and G2/M Arrest of Human Colorectal Carcinoma Cells

Chen, Y.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Study on the Cancer and Non-Cancer, Including Cardovascular Diseases, Risks in Cohort Population with Prolonged Low-Dose Radiation Exposure

Chang, W.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

The Role of Hypoxia in Transcriptomics and Epigenomics Regulation during Pre-Implantation Embryo Development

Tzeng, C.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

The Roles of Fibronectin Fragments in the Articular Chondrocytes: from Single Nucleotide Polymorphism to Functional Investigation.

Lee, C.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

In vitro and in vivo Evaluation for Silk Fibroin-Coated Electrospun Resorbable Poly(Lactic Acid) GTR Barriers

Yang, J.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Application of Diffusion Tensor Imaging to Study the White Matter Integrity and Coherence in Resting Electroencephalography

Shiu, R.

8/1/121/31/14

Project: A - Government Institutionb - Ministry of Science and Technology

Bullying Experience, Attitude and Suicide Attempts among Adolescents

Chen, P.

8/1/127/31/14

Project: A - Government Institutionb - Ministry of Science and Technology

Surface Adsorption of Nanomaterials in Applications for Gas Sensor and Catalyst

Lin, C.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Integrative Studies on Falls, Osteoporosis, and Fractures in Older People

Lin, M.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Molecular Mechanisms Underlying Statins-Suppressed Colorectal Cancer Progression: Role of P53 Family Proteins and Microrna

Hsu, M.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Enhancement of Immuno-Modulatory Capacity by Shear Stress in Mesenchymal Stem Cells

Ho, J.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Effects of Exercise Training on Sleep Disturbances, Anxiety, and Depression among Newly Diagnosed Elderly Lung Cancer Patients

Lin, C.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

The Role of DDX3 in Human Papillomavirus-Infected Lung Tumorigenesis

Lee, H.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Exploring the Effects of an Exercise Program on Female Diabetic Patients' Health

Liao, Y.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Chemokine Factors Concomitantly Induce Prostate Cancer Organ Specific Bone Metastasis

Sung, S.

8/1/129/30/13

Project: A - Government Institutionb - Ministry of Science and Technology

Study of Anti-Αlpha-Enolase I Antibodies on Cancers and Their Potential Applications

Yang, Y.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Translational Studies of Mycobacterium Tuberculosis-Induced Lung and Pleural Fibrosis

Lin, C.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Investigation of the Molecular Mechanisms of a Novel Finger Protein, Znf179, in Neuronal Differentiation

Lee, Y.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

睡眠困擾是癌症病人最常主訴的問題之一。患有睡眠困擾之癌症病人經常同時伴隨 疲憊、憂鬱等現象發生,形成症狀群集,影響生活品質。雖然目前對於癌症病人睡眠障 礙之量性研究已多有著墨,然而對於癌症病人經歷睡眠障礙之主觀經驗之瞭解,仍相當 有限。瞭解病人經歷睡眠障礙之主觀經驗,將有助於未來睡眠評估工具之修訂。另外, 在評估癌症病人睡眠品質時,若能以簡單工具評估,會更具效率及助益。阿森斯失眠量 表(Athens Insomnia Scale, AIS) 是一個簡單的8 題問卷,廣為使用在一般失眠的病人, 在癌症病人使用上,尚未有豐富的實證資料,若能建立其在癌症病人的信效度,將可作 為一簡單篩檢癌症病人失眠的工具。 睡眠遵行日夜節律規則,日夜節律又需要光作為矯正的線索,光在癌症病人睡眠的 角色,尚未有研究證實,過去研究顯示癌症病人睡眠品質不佳與生物節律有關係。光是 重要日夜節律的線索,光療法透過褪黑激素調節,調整日夜節律週期,可能可以改善睡 眠品質。另外,由於,睡眠障礙、憂鬱、疲憊經常形成一症狀群集,光療法於改善睡眠 障礙之同時,是否亦同時改善憂鬱、疲憊及生活品質。目前,光療法在癌症病人的運用 上,付之闕如,故建立光療法於癌症病人的有效性值得探究。 本研究為三年期研究計畫,目的包括有:1.瞭解癌症個案對於睡眠困擾的主觀經驗 (第一年)。2.建立阿森斯失眠量表中文版的信效度、敏感性、特異性(第一年)。3.瞭 解癌症病人光暴露與生物節率、睡眠障礙的關係(第二年)。4.瞭解光療法對於改善癌 症病人睡眠障礙及相關症狀群集、及生活品質之成效;以及瞭解光療法影響褪黑激素之 程度(第三年)。 本研究擬以癌症住院及門診病人為對象,研究工具包括基本資料、匹茲堡睡眠品質 問卷、阿森斯失眠問卷,簡明疲憊量表,貝克憂鬱量表度、SF-36 生活品質量表、腕動 力器等。資料處理分析方式包括:內容分析、描述性統計、t 檢定、皮爾森相關、GEE (generalized estimating equations)等。 本研究之結果將可瞭解光暴露與生物節率與睡眠障礙之間的關係,並可進一步瞭解 光療法作為改善癌症病人睡眠障礙之護理措施之成效,以期,最終能藉由改善癌症病人 之睡眠品質提昇病人之生活品質。

Lin, C.

8/1/1210/31/13

Project: A - Government Institutionb - Ministry of Science and Technology