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  TXNIP在肺泡巨噬細胞偏向M1/M2極化中的調控：慢性阻塞性肺病致病機轉的研究(3/3)

  Chen, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌細胞α9尼古丁受體作為新穎靶向RNA奈米藥物與T細胞療法之臨床轉譯研究-開發抗α9尼古丁受體/抗CD3雙功能抗體以一步驟建構可高效標靶毒殺乳癌腫瘤之武裝型T細胞免疫療法(1/3)

  Chuang, K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• (教學實踐) 透過PSBH®國際問題解決系列課程評量團隊合作能力提升程度研究

  Hsu, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › d - Ministry of Education

• 釐清神經類固醇的代謝在神經膠質瘤的抗藥性中扮演的角色(2/3)

  Hsu, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 纖維肌痛症：不同症狀表現型對生活品質之影響及科技輔助適性健康教練方案之成效(3/3)

  Tsai, P.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 行人低頭族風險行為探討: 以虛擬擴增實境遊戲、賽車遊戲為例

  Pai, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 性別多元的生育治理－隱默的聲音：台灣自然流產的醫學和社會形塑與 主體經驗（重點代號：L03)

  Shih, L.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 組織胺甲基化轉換酵素(HNMT)輔助臨床醫師鑑別乳癌病患作為Herceptin療效評估之新穎分子標記(2/3)

  Ho, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 金屬細懸浮微粒在慢性阻塞性肺病的第二型肺泡上皮細胞Yap/Taz調控衰老機轉之研究(1/3)

  Chuang, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 罹患重大精神與生理疾病的病人之自殺風險性以及超額死亡的探討：嵌入型病例對照研究設計

  Huang, K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建構涵蓋臨床與基因資訊之精準預測模式以改善缺血性中風病人不良預後

  Hsieh, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以電混凝浮除法同時處理火力發電廠廢水中硼與硝酸鹽之研究(1/3)

  Hu, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Bicalutamide經Sirt3/p53引發腎膈細胞電子傳遞鏈複合體I缺陷而致細胞凋亡機制的探討-輔以Idebenone及MitoTempo提升氧化磷酸化系統及調節粒線體動態之治療策略評估

  Peng, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 轉錄因子Sp1在癌細胞抗藥性所扮演角色-花生四烯酸的代謝在Sp1對神經膠質瘤與肺癌抗藥性的陰陽作用中扮演的角色(2/3)

  Chang, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 購物中心步行在地方案建立與驗證(1/2)

  Chang, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研究新穎長鏈非編碼RNA LINAT在TGF-beta訊息動態及腫瘤惡化的角色(1/3)

  Chen, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 基於深度學習與機器學習混合分析多體學數據於癌症精準醫學治療之應用評估(1/2)

  Chang, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 高齡模擬駕駛訓練對主觀認知衰退及輕度認知障礙者其執行功能、認知促進及腦波之成效分析(1/3)

  Chiu, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討小分子核糖核酸和腸道微生物在中風後血管性認知功能障礙所扮演的角色(3/3)

  Chiou, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 針對PD-L1 表現機制所發展出之口腔癌治療策略(2/3)

  Lin, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• The molecular pathogenesis of pulmonary fibrosis-Warburg effect在肺纖維化之角色(3/3)

  Chen, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探查Pearson氏症候群的基因診斷與在患者衍生細胞上的施行清除粒線體DNA缺失的可行性

  Kao, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 強化藍光之白光光照法改善纖維肌痛症患者睡眠、憂鬱、神經運動警覺度及症狀嚴重度之成效(1/3)

  Tsai, P.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 麻醉護理專業證照及進階制度之臨床能力架構與評量—客觀結構式臨床測驗(OSCE)與可信賴專業活動(EPA)等工具之建構與驗證研究(1/2)

  Chen, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討 ABCC3 調控基因/lncRNA 網絡，進而評估其抑制藥物 Fidaxomicin 作為增強 temozolomide 對腦瘤毒殺能力佐劑之可行性

  Chen, K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• CCR5標靶微脂粒包覆免疫抑制藥物Tacrolimus治療自體免疫疾病之研究(2/3)

  Liu, D.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 肺纖維化之分子病理機制探討-ADAM17/preadipocyte factor-1在缺氧誘導CTGF表現及呼吸道纖維化角色探討(3/3)

  Chen, B.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研究肺氣腫發展中調控細胞老化的分子機轉: 前胸腺素-HuR-SIRT1路徑

  Su, B.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發蛋白質雙硫鍵異構酶抑制劑作為抗多形性神經膠質母細胞瘤藥物

  Huang, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研究PKLR促進前列腺癌神經內分泌分化之代謝途徑及其治療角色(1/3)

  Liu, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 桑黃天然物hispolon及其結構衍生物延緩老化與神經退化疾病的研究:從體外試驗到體內動物模式(3/3)

  Hou, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建構空氣汙染物、易感受性基因及傳統危險因子對於缺血性中風風險之個人化精準預測模式(2/3)

  Chiou, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新穎性選擇性HDAC抑制劑之抗癌藥物開發與藥理機轉探討(3/3)

  Pan, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 早幼粒細胞白血病鋅指蛋白(PLZF)對腦部發育的多重功能之探討(3/3)

  Lee, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 絲氨酸/蘇氨酸蛋白激酶(SIK3)參與乳癌致癌過程的分子機制探討

  Chen, L.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討ARE結合蛋白質與選擇性聚腺甘酸化作用在人類大腸直腸癌上所扮演的角色(3/3)

  Liang, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以上皮間質轉化的觀點來探討臨床濃度Lidocaine對大腸癌腫瘤移動的影響

  Lin, J. A.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 紫杉醇調控血小板活化、細胞凋亡和自我吞噬之分子機轉探討:體內及體外試驗(1/3)

  Lu, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• RAB3C對大腸直腸癌之抗藥性與腫瘤免疫反應影響之探討(1/3)

  Chen, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 藉由調控神經包網結構來改善早期社交孤立所誘發於模棱兩可的資訊下異常恐懼記憶連結的形成(1/3)

  Yang, C. H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 芳香烴受體於眼科疾病之治療潛力機制探討-探討芳香烴受體活化在青光眼病程的視網膜保護角色(1/3)

  Hsiao, G.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 透過感恩行為影響學生在大體解剖學實驗課程中的情緒感受與調適並強化家訪的效果

  Chiou, R.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌細胞受體專一性RNA適體奈米質粒誘發第三型玻尿酸合成酵素的抗癌機制探討(1/3)

  Tu, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用轉錄體學與蛋白質體學方法探討膀胱癌對鉑類藥物產生抗藥性之分子機轉研究並開發新的治療策略(第二年)

  Chen, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建立類神經網路模型以評估手術病患發生呼吸中止與低血氧的風險

  Chang, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 闡明Hiltonol為主的複合式用藥在肺癌生長，轉移和腫瘤微環境中的作用。

  Chang, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 結合奈米診斷治療、影像免疫基因圖譜與人工智慧於原發性與再復發膠質母細胞瘤之研究-開發新穎結構小分子抑制劑用來抑制血管生成和腫瘤微環境以治療原發性及復發性多型性神經膠質母細胞腦瘤患者(2/3)

  Huang, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建立探討膜蛋白折疊的研究平台(2/3)

  Chang, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以新式片狀細胞工學製備自體片狀心肌細胞及其應用在缺血性心臟病的動物模式

  Tseng, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 標靶B型肝炎誘發之肝癌腫瘤生成與Sorafenib抗藥性之微環境：聚焦發炎激素與癌幹細胞特性之轉譯精準醫學研究與臨床意義-探討微環境發炎細胞激素與基因後生調節於B型肝炎病毒誘導之肝癌表現多能性幹細胞基因OCT4與Sorafenib抗藥性之調控機制與其臨床意義(3/3)

  Huang, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology