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• b - Ministry of Science and Technology

  從食品風險暴露之角度探討非營養性甜味劑對女性生殖狀況之影響-非營養性甜味劑對子宮收縮及生殖細胞之影響效應及相關機轉探討(1/3)

  Hsia, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Cellular and Molecular Mechanisms with Epigenetic Regulation by Histone Deacetylation on Postopratetive Atrial and Pulmonary Vein Arrhythmogenesis

  Chen, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Research and development of on-line incremental Learning schemes for Big Data Analytics in non-stationary environments

  Chiang, I.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Vaccine Liability and Vaccine Injury Compensation Program’s Influences on the Production and Use of Vaccines

  Ho, J.

  1/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Huntingtin-Associated Protein Related Biomarkers in Neural Survival

  Lin, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the Pathophysiological Role of Microrna in the Development of Emphysema(3/3)

  Su, B.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Exploring the Relevant Factor of Job Sustainability among Middle-Aged and Elderly Workers in Taiwan

  Chin, W.

  1/1/20 → 12/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 強化藍光之白光光照法改善纖維肌痛症患者睡眠、憂鬱、神經運動警覺度及症狀嚴重度之成效(1/3)

  Tsai, P.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Longitudinal Study of the Individualized Walking Exercise Program on Memory, Subjective Cognitive Complaint, and Brain-Derived Neurotrophic Factor (Bdnf) among Postmenopausal Hypertensive Women

  Chou, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Association of Training Process, Duty Hour, and Self-Identity Building of Young Physicians

  Chiu, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用基因網絡分析尋找假定蛋白質 （hypothetical protein)與抗藥性的關係

  Wu, Y.

  7/1/18 → 2/28/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Galectin-1 in Liver Fibrosis

  Wu, M.

  1/1/13 → 3/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the Klf10 alters metabolic pathways in genetic-deficient mice and human pancreatic ductal carcinomas

  Chang, H.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• 抗免疫監測點抑制因子PD1 與PDL1的嵌合抗原受體修飾性γδ-T細胞用於治療卵巢癌療效之探討

  Liu, C.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討新型benzimidazole衍生物抑制肝癌抗藥性細胞生長的角色

  Liao, Y.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• MCPIPs鋅指蛋白家族在人類大腸直腸癌組織的表現及調控Akt訊息傳遞路徑之研究

  Liang, Y.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development and Applications of an Integrated Epitope Prediction System for Cancer Peptide-Based Vaccine Design in Translational Bioinformatics

  Su, E. C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Fibromyalgia: Impacts of Different Phenotypes on Quality of Life and the Effects of Technology-Assisted and Tailored Health Coaching(1/3)

  Tsai, P.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Mechanisms and Therapeutic Strategies of Pd-L1 Expression in Oral Cancers( I )(1/3)

  Lin, H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討B型肝炎相關肝癌中HBx蛋白與其相關之表觀遺傳調控因子促進SENP1表現與癌幹細胞特性：HBx/SENP1之角色與臨床意義(3/3)

  Wu, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 中文版理察斯-坎貝爾睡眠量表於重症病人之測量特性：以古典測試理論與試題反應理論驗證

  Chiu, H.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study and Implementation of Patient Privacy Protection under the Framework for Electronic Medical Records Exchange in Taiwan

  Liu, C.

  8/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Targeting Cancer Cell’s Metabolism for Treatment of Human Malignant Glioma

  Lee, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• 核糖核甘酸還原酉每抑制劑在人類乳突瘤病毒感染之非小細胞肺癌治療效果評估

  Hsu, N.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Can Sesamin Alone or Cotheapy with Anti-DM Medicines Alleviate the Abnormal Intermediate Metabolites of Glucose and Fatty Acids, the Oxygen Consumption and Renal Fibrotic Progression?

  Peng, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Improvements of Glutamine, Epidermal Growth Factor and Synbiotics on Alcoholic Liver Diseases by the Intestinal Health

  Yang, S.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

• A series of studies analyzing exercise behavior and exploring the effects of interventions among pre-diabetes, type 1, and type 2 diabetes

  Jeng, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Dissected the Role of Alpha-7 Nicotinic Receptor in the Prognosis and Clinical Therapy on Gastric Cancers

  Chang, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Enhancement of Immuno-Modulatory Capacity by Shear Stress in Mesenchymal Stem Cells

  Ho, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Empower Breastfeeding: Effects of an Integrated Breastfeeding Education Program on Optimal Breastfeeding Practice

  Kuo, S.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用智慧型穿戴裝置探討複方藥物昂帝博膠囊對COPD患者自主神經活性的影響、心律變異度的變化及其與發炎因子之相關性

  Ho, S.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation the Functional Roles and Molecular Mechanism of Long Non-Coding Rna-Crnde in Autophagy and Oxaliplatin Drug Resistance

  Lee, K.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Study the Regulation of Macrophage Polarization and Disease Progression with Specific Haptoglobin Phenotypes in Patients with Chronic Obstructive Pulmonary Disease

  Ho, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Use of non-invasive creative art therapy to improve the spiritual health of advanced patients

  Huang, T.

  1/1/20 → 12/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 在慢性阻塞性氣喘中double cortin like kinase 1 (DCLK1)在thrombin誘導IL-8/CXCL8表現及氣道發炎的病理角色之研究(1/3)

  Chen, B.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 不孕症婦女心理困擾變化軌跡：身心療癒措施結合心率變異生理回饋之成效與機轉(3/3)

  Kuo, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation on the Epigenetic Regulation of Autophagy

  Yang, P.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Structural and Functional Studies on the Virulence Regulators SaeR/S in Staphylococcus aureus

  Liu, C.

  12/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Potential Application of the Staphylococcus aureus DNA Mimic Protein Saugi in Combating Human Viral Disease

  Wang, H.

  10/1/13 → 9/30/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• 睡眠困擾是癌症病人最常主訴的問題之一。患有睡眠困擾之癌症病人經常同時伴隨 疲憊、憂鬱等現象發生，形成症狀群集，影響生活品質。雖然目前對於癌症病人睡眠障 礙之量性研究已多有著墨，然而對於癌症病人經歷睡眠障礙之主觀經驗之瞭解，仍相當 有限。瞭解病人經歷睡眠障礙之主觀經驗，將有助於未來睡眠評估工具之修訂。另外， 在評估癌症病人睡眠品質時，若能以簡單工具評估，會更具效率及助益。阿森斯失眠量 表(Athens Insomnia Scale, AIS) 是一個簡單的8 題問卷，廣為使用在一般失眠的病人， 在癌症病人使用上，尚未有豐富的實證資料，若能建立其在癌症病人的信效度，將可作 為一簡單篩檢癌症病人失眠的工具。 睡眠遵行日夜節律規則，日夜節律又需要光作為矯正的線索，光在癌症病人睡眠的 角色，尚未有研究證實，過去研究顯示癌症病人睡眠品質不佳與生物節律有關係。光是 重要日夜節律的線索，光療法透過褪黑激素調節，調整日夜節律週期，可能可以改善睡 眠品質。另外，由於，睡眠障礙、憂鬱、疲憊經常形成一症狀群集，光療法於改善睡眠 障礙之同時，是否亦同時改善憂鬱、疲憊及生活品質。目前，光療法在癌症病人的運用 上，付之闕如，故建立光療法於癌症病人的有效性值得探究。 本研究為三年期研究計畫，目的包括有：1.瞭解癌症個案對於睡眠困擾的主觀經驗 （第一年）。2.建立阿森斯失眠量表中文版的信效度、敏感性、特異性（第一年）。3.瞭 解癌症病人光暴露與生物節率、睡眠障礙的關係（第二年）。4.瞭解光療法對於改善癌 症病人睡眠障礙及相關症狀群集、及生活品質之成效；以及瞭解光療法影響褪黑激素之 程度（第三年）。 本研究擬以癌症住院及門診病人為對象，研究工具包括基本資料、匹茲堡睡眠品質 問卷、阿森斯失眠問卷，簡明疲憊量表，貝克憂鬱量表度、SF-36 生活品質量表、腕動 力器等。資料處理分析方式包括：內容分析、描述性統計、t 檢定、皮爾森相關、GEE (generalized estimating equations)等。 本研究之結果將可瞭解光暴露與生物節率與睡眠障礙之間的關係，並可進一步瞭解 光療法作為改善癌症病人睡眠障礙之護理措施之成效，以期，最終能藉由改善癌症病人 之睡眠品質提昇病人之生活品質。

  Lin, C.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of the transcriptional and epigenetic mechanisms for the Nm23-H1 expression: An nm23-H1-promoter screening platform for novel metastasis-suppressing anticancer drugs

  Wang, L.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Effect of Long Acting GnRH Agonist Treatment on Mitochondrial Function in

  Tzeng, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Electrophysiological Activity and Functional Correlates in Female Pelvic Floor Muscles(2)

  Yang, J.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• From Hospital to Community: Longitudinal Changes of Participation in Younger Stroke Survivors

  Chang, F.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigate the Molecular Mechanisms Involved in Enhancing Photodynamic Thetapy Using an Old Antibiotic Agent

  Tsai, T.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Effect of Muscle Strength Training on Body Composition and Sarcopenic Obesity among the Female Overweight Elderly

  Liou, T.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Randomized Controlled Study of Aquatic Exercise Program for Cognitive Frailty Older People’S Gait, Balance, Cognitive Function and Fall Risk.

  Chiu, H.

  3/1/19 → 2/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 國際產學聯盟計畫III

  Lin, C.

  9/1/19 → 8/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Novel Small Molecules Nsc771784 and Nsc772867 for Breast Cancer Therapy with Brain Metastasis

  Lundy, D.

  10/1/19 → 4/30/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of CD24 in TNF-Alpha-Inhibited Erythroid Differentiation and Its Signaling Pathway

  Huang, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology