Find Research Projects

Search results

• Finished

  Assessing Risk and Progression of Knee Osteoarthritis via Loading Rate and T2 Mapping of Cartilage

  Chan, W. P.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular mechanisms of propofol-involved protection against ischemia brain injuries

  Chen, T.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Indoxyl Sulfate, Chronic Kidney Disease and Heat Shock Protein Modulate the Atrial Electrophysiological Characteristics

  Hsieh, M.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Sleep and Memory Consilidation in Alzheimer Disease

  Hu, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Chitosan nanoparticle as a macrophage-targeting drug delivery carrier

  Mi, F.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Preceptors’ perceptions of training programs and training needs, experienced barriers during precepting, and development and effectiveness evaluation of a preceptor intervention

  Chang, W.

  8/1/13 → 10/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Effects of Music Therapy on Psychological Distress and Functional Recovery in Patients With Stroke

  Chang, H.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Molecular and Clinical Role of microRNA in Obesity Induced Nephropathy

  Lin, H.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Study the Correlation between Serum Markers of Oxidative Stress, Inflammation, and Endocrine-Disrupting Chemicals (Edcs) and Their Impact on the Menstrual Cycle and Reproductive Hormone in Taiwanese Women

  Hsu, M.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of fish oil on alcoholic liver disease in rats based on pathological mechanisms

  Yang, S.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Use the organometal catalytic reaction to synthesize the heterocycle-based anticancer agents

  Liou, J.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Roles of Novel CCCH Zinc Finger Genes on the Regulation of Cell Proliferation and Inflammation

  Liang, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Optimization of Human Meniscus Imaging and Its Clinical Application for Osteoarthritis

  Tsai, P.

  8/1/13 → 10/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Effects of LED Light on Porphyromonas gingivalis in Periodontitis for Anti-Inflammation and Alveolar Bone Regeneration

  Deng, W.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• End-of-Life Care for Elderly with Advanced Dementia in Long-Term Care Facilities

  Chang, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Association between lipid, glucose related genes and prognosis of intra- and extra-cranial stenosis in stroke patients

  Chiou, H.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Association Study of Genetic Polymorphisms of Toll-Like Receptors on Ischemic Stroke (I)

  Chiou, H.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Association of Epidermal Growth Factor Receptor mutations with HPV16/18 E6 Oncoprotein Expression in Non-Small Cell Lung Cancer

  Lee, H.

  8/1/13 → 7/31/14

  Project: C - Project of Alliance › r - Tung's Taichung MetroHarbor Hospital

• The Effects of Neurofeedback and Rsa Biofeedback on Quality of Sleep in Patients in the Chronic Phase of Traumatic Brain Injury

  Tsai, P.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Vector-Borne Disease Forecasting Models Using Satellite Remote Sensing Techniques

  Chuang, T.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Community-based Screening and Prevention Model for Periodontal Disease

  Chen, L.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Hospital Patient Safety Culture-Comparison of Major Measurement Tools, Promotion Methods and Their Evaluation

  Kuo, N.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Deferasirox Plasma Concentration Analysis and Effects of Potential Iron Chelators on Iron Overload and Safety Evaluation

  Wu, T.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the Therapeutic Effects and Novel Molecular Mechanisms of Resveratrol in Human Osteosarcoma: the Treatment of Metastatic Cancer

  Chien, M.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Investigate the Functions of Shikonin and Its Derivatives in Applied Age-Related Macular Degeneration and Wound Healining

  Cheng, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• TMU101-AE1-B63

  Chen, C.

  8/1/13 → 7/31/14

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• Roles of Central OX2R Activities in the Pathophysiology of Hypertension in SHR

  Hwang, L.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies on the carcinogenic mechanisms of histamine N-methyltransferase-mediated breast cancer formation

  Wu, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Functional Characterization of Niemann-Pick Type C2 Protein in Hepatocellular Carcinoma

  Liao, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Neurotrophic/Neuroprotective Role of GIP in Cellular and Rodent Models of Mild Traumatic Brain Injury (II)

  Lin, J.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Plant metabolomics (1. Agave sisalana, 2. Anoectochilus formosanus, 3. phalaenopsis spp.)

  Lee, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Effects of Music Listening on Pain, Heart Rate Variability and Joint Range of Motion for Patints Receving Total Knee Replacement

  Lin, P.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Evaluation of Therapeutic Correlation of Nanomedicine with Tea Polyphenol for Inhibition of Ocular Surface Inflammation in Rabbit Dry Eye Model

  Tseng, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Design and Characterization of Multifunctional Self-Assembling Lecithin/Amphiphilic Polymers Mixed Micellar Delivery Systems

  Sheu, M.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• An association study of arsenic exposure, inflammation, oxidative stress and the risk of developing cardiovascular diseases

  Hsieh, F.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Explore of Toll-Like Receptors Associated Mirna Expression in Ischemic Stroke Patients (I)

  Wu, C.

  8/1/13 → 7/31/14

  Project: B - Project of TMU › i - Other (Funded by TMU)

• The Effect of Muscle Strength Training on Body Composition and Sarcopenic Obesity among the Female Overweight Elderly

  Liou, T.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• 大腸直腸癌已躍居世界上癌症死亡率第二名，屬於固體型腫瘤，缺氧常見於此類 腫瘤，並誘發HIF-1α 表現而導致抗藥性及預後較差，因此抑制HIF-1α 被視為新的抗 癌策略。Zebularine (Zeb)是較穩定之DNA methyltransferase (DNMT)抑制劑，可殺死癌 細胞而不影響正常細胞，對小鼠也不具毒性。我們初步結果顯示，Zeb 可抑制人類大 腸癌細胞株HCT116 之HIF-1α表現，代表Zeb 是治療大腸直腸癌之潛力藥物。我們的 初步也證明Zeb對HCT116具毒殺性，對小鼠大腸癌也有療效。細胞自我吞噬(autophagy) 是指細胞在惡劣環境下，經由吞噬細胞內物質產生能量渡過外界壓力的一種保護機 制；也有研究報導指出，藥物會誘導癌細胞產生autophagy，造成細胞過度吞噬其內容 物而死亡，因此，autophagy在癌細胞為保護或是引發毒殺作用，目前仍無定論。缺氧 也會透過HIF-1α 導致autophagy 而促進細胞存活，但嚴重缺氧或無氧狀態則可透過活 化AMPK及unfolded protein response (UPR)造成autophagic cell death。我們初步結果顯 示，除抑制HIF-1α 表現外，Zeb 也可活化AMPK、UPR/ER stress、以及autophagy， 因此我們推測Zeb 可在缺氧狀態下，促進autophagic cell death。3 年內我們將執行4 項 目標： (1) 探討Zeb 在各種癌細胞及活體模式之抗癌作用。（第一年） (2) 研究Zeb 抑制HIF-1α表現之分子機轉。（第一年到第二年） (3) 研究Zeb 誘發autophagy之分子機轉。（第二年到第三年） (4) 探討Zeb 對缺氧導致抗藥性之作用。（第三年）

  Yang, P.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Clinical Correlation study of DNA Methyltransferases Alterations in Breast Cancer and Evaluation of DNA Methyltransferases as a Therapeutic Target in Cell and Animal Models

  Lin, R.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Strontium-Impregnated Bioabsorbable Bone Screw for Fracture Fixation in Osteoporotic Bone

  Yang, K.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Effect of Improved Nutrition Care on the Progress of Hemodialysis Patients

  Yang, S.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• TMU101-AE1-B65

  Wang, T.

  8/1/13 → 7/31/14

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• Effects of Exercise Training on Sleep Disturbances, Anxiety, and Depression among Newly Diagnosed Elderly Lung Cancer Patients

  Lin, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Exploratory Study of Self-Identity and Medical Professionalism Among Medical Students

  Chiu, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• TMU101-AE1-B47

  Liu, F.

  8/1/13 → 7/31/16

  Project: B - Project of TMU › i - Other (Funded by TMU)

• α9-型尼古丁乙醯膽鹼受體在乳癌幹細胞的角色與防治藥物的篩選

  Lai, G.

  8/1/13 → 7/31/14

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Effects of a program of mind-body interventions on psychological resilience, vagal tone, emotional states, and outcomes of heart failure

  Tsai, P.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies on the anti-islet hypertrophy and anti-osteoporosis constituents from Formosan Fern

  Hsu, F.

  8/1/13 → 12/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Survey and Intervention of Health Literacy among Older Adults

  Chi, M.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study of the mechanism of HPV involved tumorigenesis through Wnt signaling pathway related microRNA regulation

  Cheng, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology