Find Research Projects

Evaluation of the Effects of Selective Serotonin Reuptake Inhibitor on High Grade Glioma

Shen, S.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Modulation of Tumor Microenvironment by Nucleic Acid Chimeras as a New Paradigm for Adjuvant Cancer Therapy

Yeh, S.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

包載9α-型尼古丁乙醯膽鹼受體抑制劑之標靶性微脂體劑型設計與開發

Sheu, M.

8/1/127/31/13

Project: B - Project of TMUh - Other (Funded by TMU)

Studies on the Carcinogenic Mechanisms of Histamine N-Methyltransferase-Mediated Breast Cancer Formation

Wu, C.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Renoprotective Mechanisms of Soy Protein in Rats with Diabetic Nephropathy

Chen, J.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

睡眠困擾是癌症病人最常主訴的問題之一。患有睡眠困擾之癌症病人經常同時伴隨 疲憊、憂鬱等現象發生,形成症狀群集,影響生活品質。雖然目前對於癌症病人睡眠障 礙之量性研究已多有著墨,然而對於癌症病人經歷睡眠障礙之主觀經驗之瞭解,仍相當 有限。瞭解病人經歷睡眠障礙之主觀經驗,將有助於未來睡眠評估工具之修訂。另外, 在評估癌症病人睡眠品質時,若能以簡單工具評估,會更具效率及助益。阿森斯失眠量 表(Athens Insomnia Scale, AIS) 是一個簡單的8 題問卷,廣為使用在一般失眠的病人, 在癌症病人使用上,尚未有豐富的實證資料,若能建立其在癌症病人的信效度,將可作 為一簡單篩檢癌症病人失眠的工具。 睡眠遵行日夜節律規則,日夜節律又需要光作為矯正的線索,光在癌症病人睡眠的 角色,尚未有研究證實,過去研究顯示癌症病人睡眠品質不佳與生物節律有關係。光是 重要日夜節律的線索,光療法透過褪黑激素調節,調整日夜節律週期,可能可以改善睡 眠品質。另外,由於,睡眠障礙、憂鬱、疲憊經常形成一症狀群集,光療法於改善睡眠 障礙之同時,是否亦同時改善憂鬱、疲憊及生活品質。目前,光療法在癌症病人的運用 上,付之闕如,故建立光療法於癌症病人的有效性值得探究。 本研究為三年期研究計畫,目的包括有:1.瞭解癌症個案對於睡眠困擾的主觀經驗 (第一年)。2.建立阿森斯失眠量表中文版的信效度、敏感性、特異性(第一年)。3.瞭 解癌症病人光暴露與生物節率、睡眠障礙的關係(第二年)。4.瞭解光療法對於改善癌 症病人睡眠障礙及相關症狀群集、及生活品質之成效;以及瞭解光療法影響褪黑激素之 程度(第三年)。 本研究擬以癌症住院及門診病人為對象,研究工具包括基本資料、匹茲堡睡眠品質 問卷、阿森斯失眠問卷,簡明疲憊量表,貝克憂鬱量表度、SF-36 生活品質量表、腕動 力器等。資料處理分析方式包括:內容分析、描述性統計、t 檢定、皮爾森相關、GEE (generalized estimating equations)等。 本研究之結果將可瞭解光暴露與生物節率與睡眠障礙之間的關係,並可進一步瞭解 光療法作為改善癌症病人睡眠障礙之護理措施之成效,以期,最終能藉由改善癌症病人 之睡眠品質提昇病人之生活品質。

Lin, C.

8/1/1210/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Effects of Exercise Training on Sleep Disturbances, Anxiety, and Depression among Newly Diagnosed Elderly Lung Cancer Patients

Lin, C.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Roles of Central Orexin Activities in the Pathophysiology of Hypertension in Shr

Hwang, L.

8/1/129/30/13

Project: A - Government Institutionb - Ministry of Science and Technology

Therapeutic Strategies for Traumatic Brain Injury with Novelly Desinged Drugs( I )

Wang, J.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

The Neurotrophic/Neuroprotective Role of Gip in Cellular and Rodent Models of Mild Traumatic Brain Injury.( I )

Lin, J.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Investigation of the Molecular Mechanisms of a Novel Finger Protein, Znf179, in Neuronal Differentiation

Lee, Y.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

The Role of Microrna Let-7g in Cytosolic Ca2+ Regulation and Cox-2 Gene Expression

Chang, W.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Effects of Essential Oils on Smooth Muscle Contraction in Rat Uterus (Gm07)

Hsia, S.

8/1/1212/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Pulmonary Effects of Chorioamnionitis and Postnatal Hyperoxia in Rat Offspring

Chen, C.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Translational Studies of Mycobacterium Tuberculosis-Induced Lung and Pleural Fibrosis

Lin, C.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

The Role and Molecular Mechanism of Pparα in Acute Kidney Injury: Focus on the Protective Effect in Renal Tubular Cell

Hsu, Y.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

轉錄因子Sp1在腦神經損傷所扮演隻角色(1/3)

Chang, W.

8/1/127/31/13

Project: B - Project of TMUh - Other (Funded by TMU)

Role of Sp-Family in Lung Tumorigenesis

Chang, W.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Dissected the Role of Alpha-7 Nicotinic Receptor in the Prognosis and Clinical Therapy on Gastric Cancers

Chang, Y.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

NF-kB以及NF-kB repressing factor (NRF) 在慢性阻塞性肺疾病引發系統性發炎之角色探討(3/3)

Lee, K.

8/1/1210/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Translational Genomic Approaches in Endometriosis

Tzeng, C., Kao, S., Huang, Y., Yang, W., Yang, W., Yeh, C., Li, Y. & Shen, S.

8/1/1210/31/13

Project: B - Project of TMUh - Other (Funded by TMU)

The First Randomized Controlled Clinical Trial for Computerized Decision Support System (II)

Li, Y.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

The Roles of Genetic Polymorphisms for Susceptibility and Clinical Outcomes of Colorectal Cancer in Taiwanese Lynch Syndrome Families

Yeh, C.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Effects of Maternal Depressive Symptomatology on Pregnancy Outcomes and Newborn Development---How Is Paternal Psychopathology Involved?

Chen, Y.

8/1/129/30/13

Project: A - Government Institutionb - Ministry of Science and Technology

21世紀的公民與風險:全球變遷中的環境,知識和價值

Chiou, H.

8/1/1212/31/13

Project: A - Government Institutiond - Ministry of Education

探討加護病房多種致病微生物揮發性有機成分

Shih, C.

7/25/1211/30/12

Project: A - Government Institutionf - Other (Funded by Government)

The studies and analysis of the addiction,abuse and social risk of emerging abused drugs

Sheu, S.

7/10/1212/31/12

Project: A - Government Institutionc - Ministry of Health and Welfare

護理碩士進階實務人才培育共識論壇

Lin, C.

7/6/127/27/12

Project: A - Government Institutiond - Ministry of Education

以混合羅吉特模型分析機車路口使用兩段式左轉之行為

Pai, C.

7/5/129/3/13

Project: A - Government Institutionb - Ministry of Science and Technology

101年度建置健保法學知識數位平台

Yang, C.

6/29/1212/28/12

Project: A - Government Institutionc - Ministry of Health and Welfare

Research Symposium for Chinese Medicine Research Projects

Liang, W., Huang, W. & Lin, M.

6/1/1212/15/12

Project: A - Government Institutionc - Ministry of Health and Welfare

Feasibility of Capitation for the Accountable Family Physician System: An Exploratory Study

Sheu, M., Hsu, Y. & Wen, H.

5/2/123/31/13

Project: A - Government Institutionc - Ministry of Health and Welfare

探討以植物化學成分抑制β-catenin/PIN1訊息傳道路徑於肝癌幹細胞的發生

Wu, T. A.

5/1/124/30/13

Project: C - Project of Alliancet - Taipei Medical University Shuang Ho Hospital

利用電漿表面改質促進鈦植體表面生物相容性之研究

Peng, P.

5/1/124/30/13

Project: C - Project of Allianceo - Taipei Medical University Hospital

以MALDI與TOF-SIMS研究大腸癌組織Heme oxygenase-1與腫瘤相關蛋白及鐵離子表現變化

Chang, J.

5/1/124/30/14

Project: C - Project of Alliances - Taipei Municipal Wanfang Hospital

探討女性糖尿病患之泌尿道症狀、睡眠品質與糖尿病控制的相關

Liao, Y.

5/1/124/30/13

Project: C - Project of Alliances - Taipei Municipal Wanfang Hospital

以超靈敏奈米線感測器偵測口腔癌症指標

Wu, C.

5/1/125/31/13

Project: C - Project of Allianceo - Taipei Medical University Hospital

跑步機運動對巴金森氏病患者步態、認知功能、運動功能及生活品質之改善成效

Yuan, R.

5/1/124/30/13

Project: C - Project of Allianceo - Taipei Medical University Hospital

以彈性工程提升加護病房病人安全之應用研究

Chuang, S.

5/1/1210/31/13

Project: C - Project of Allianceo - Taipei Medical University Hospital

α2A-Adrenergic receptor在加護病房新興鎮靜藥物dexmedetomidine誘發神經保護作用過程中所扮演的角色研究

Wu, G.

5/1/124/30/13

Project: C - Project of Alliancet - Taipei Medical University Shuang Ho Hospital