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Endothelin-1 Mediates Fibrocyte Differentiation in Chronic Obstructive Asthma

Lin, C.

8/1/127/31/13

Project: B - Project of TMUi - Other (Funded by TMU)

Phosphoproteomic Study on Mechanisms of Silymarin Modulating Fungicide Induced Sperm Dysfunction

Wu, T.

8/1/1210/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Translational Studies of Mycobacterium Tuberculosis-Induced Lung and Pleural Fibrosis

Lin, C.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

榖胱甘月太硫轉移酉每參與乳癌致癌之分子機制探討(1/3)

Wu, C.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Translational Genomic Approaches in Endometriosis

Tzeng, C., Kao, S., Huang, Y., Yang, W., Yang, W., Yeh, C., Li, Y. & Shen, S.

8/1/1210/31/13

Project: B - Project of TMUi - Other (Funded by TMU)

Plant Metabolomics---1. Agave sisalana; 2. Anoectochilus formosanus; 3. Phalaenopsis spp.

Lee, C.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

The Role of Microrna Let-7g in Cytosolic Ca2+ Regulation and Cox-2 Gene Expression

Chang, W.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

The Roles of Genetic Polymorphisms for Susceptibility and Clinical Outcomes of Colorectal Cancer in Taiwanese Lynch Syndrome Families

Yeh, C.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Lay Health Knowledge Research:Example of Infants and Children Dietary Supplement

Chen, Y. C.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Study of Anti-Αlpha-Enolase I Antibodies on Cancers and Their Potential Applications

Yang, Y.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

The Role of DDX3 in Human Papillomavirus-Infected Lung Tumorigenesis

Lee, H.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

The Biological Mechanisms of N-3 Polyunsaturated Fatty Acid Treatment in Interferon-Induced Depression

Huang, S.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Effects of Adlay Hull Extracts on Polycystic Ovary Syndrome (Pcos)

Hsia, S.

8/1/1210/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

睡眠困擾是癌症病人最常主訴的問題之一。患有睡眠困擾之癌症病人經常同時伴隨 疲憊、憂鬱等現象發生,形成症狀群集,影響生活品質。雖然目前對於癌症病人睡眠障 礙之量性研究已多有著墨,然而對於癌症病人經歷睡眠障礙之主觀經驗之瞭解,仍相當 有限。瞭解病人經歷睡眠障礙之主觀經驗,將有助於未來睡眠評估工具之修訂。另外, 在評估癌症病人睡眠品質時,若能以簡單工具評估,會更具效率及助益。阿森斯失眠量 表(Athens Insomnia Scale, AIS) 是一個簡單的8 題問卷,廣為使用在一般失眠的病人, 在癌症病人使用上,尚未有豐富的實證資料,若能建立其在癌症病人的信效度,將可作 為一簡單篩檢癌症病人失眠的工具。 睡眠遵行日夜節律規則,日夜節律又需要光作為矯正的線索,光在癌症病人睡眠的 角色,尚未有研究證實,過去研究顯示癌症病人睡眠品質不佳與生物節律有關係。光是 重要日夜節律的線索,光療法透過褪黑激素調節,調整日夜節律週期,可能可以改善睡 眠品質。另外,由於,睡眠障礙、憂鬱、疲憊經常形成一症狀群集,光療法於改善睡眠 障礙之同時,是否亦同時改善憂鬱、疲憊及生活品質。目前,光療法在癌症病人的運用 上,付之闕如,故建立光療法於癌症病人的有效性值得探究。 本研究為三年期研究計畫,目的包括有:1.瞭解癌症個案對於睡眠困擾的主觀經驗 (第一年)。2.建立阿森斯失眠量表中文版的信效度、敏感性、特異性(第一年)。3.瞭 解癌症病人光暴露與生物節率、睡眠障礙的關係(第二年)。4.瞭解光療法對於改善癌 症病人睡眠障礙及相關症狀群集、及生活品質之成效;以及瞭解光療法影響褪黑激素之 程度(第三年)。 本研究擬以癌症住院及門診病人為對象,研究工具包括基本資料、匹茲堡睡眠品質 問卷、阿森斯失眠問卷,簡明疲憊量表,貝克憂鬱量表度、SF-36 生活品質量表、腕動 力器等。資料處理分析方式包括:內容分析、描述性統計、t 檢定、皮爾森相關、GEE (generalized estimating equations)等。 本研究之結果將可瞭解光暴露與生物節率與睡眠障礙之間的關係,並可進一步瞭解 光療法作為改善癌症病人睡眠障礙之護理措施之成效,以期,最終能藉由改善癌症病人 之睡眠品質提昇病人之生活品質。

Lin, C.

8/1/1210/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Application of Diffusion Tensor Imaging to Study the White Matter Integrity and Coherence in Resting Electroencephalography

Shiu, R.

8/1/121/31/14

Project: A - Government Institutionb - Ministry of Science and Technology

Community-Based Screening and Prevention Model for Periodontal Disease

Chen, L.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Advanced Research for a Decision Model of Emergency Patient Intelligent Dispatch

Hsu, C.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Study the Klf10 Alters Metabolic Pathways in Genetic-Deficient Mice and Human Pancreatic Ductal Carcinomas

Chang, H.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

The First Randomized Controlled Clinical Trial for Computerized Decision Support System (II)

Li, Y.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

The Role of Cytoplasmic APe1 in Tumor Malignancy, Drug Resistance and Lung Cancer Prognosis

Lee, H.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

依療法律與醫學倫理

Ho, J.

8/1/121/31/13

Project: A - Government Institutiond - Ministry of Education

Combine Anesthesia Information System with Artificial Neural Networks to Develop the Surgical Complication Pre-Warning System

Lin, C.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Avoidable Hospitalizations and Primary Care Manpower in a Universal Health Insurance System: a 15-Year Trend Analysis

Huang, K.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Roles of Central Orexin Activities in the Pathophysiology of Hypertension in Shr

Hwang, L.

8/1/129/30/13

Project: A - Government Institutionb - Ministry of Science and Technology

Novel Roles of Arnt in Breast Tumor Progression, Metastasis and Therapy

Chang, W.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

The Role of Cd69 in Tnfalpha-Inhibited Erythroid Differentiation

Huang, H.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

The Roles of Micrornas in Endothelin-1 and Hypoxia-Induced Ctgf Production

Chen, Y.

8/1/127/31/14

Project: B - Project of TMUi - Other (Funded by TMU)

Epigenetic Regulation of Lps-Induced G-Csf Expression in Macrophages

Chang, S.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Dissected the Role of Alpha-7 Nicotinic Receptor in the Prognosis and Clinical Therapy on Gastric Cancers

Chang, Y.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Study of Laser Enhancement of Transdermal Delivery of Nanoparticles

Lee, W.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Cytotoxicity and Application on Drug Resistant Cells of Halide Derivatives of Rutaecarpine

Lin, C.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

A Study on the Evaluation of Stromal Stem Cells and Stromal Fibroblasts in Human Tissue Regenerative and Cancer Forming Potentials

Shih, T.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Effects of Indoor Air Quality Improvement on Cardiovascular Health in General Population

Chuang, K.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

The Effects of the Apoe4 Allele on Cerebral Structural and Functional Connectivity- a Diffusion Tensor Imaging and Resting-State Mri Study

Chen, C.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Molecular Mechanisms Underlying Statins-Suppressed Colorectal Cancer Progression: Role of P53 Family Proteins and Microrna

Hsu, M.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Studies of Molecular and Cellular Underlying Mechanisms of Ferrous Citrate-Induced Cerebral Vasospasm and Brain Injury

Lee, W.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Therapeutic Strategies for Traumatic Brain Injury with Novelly Desinged Drugs( I )

Wang, J.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Roles of Autophagy and Heme Oxygenases(-1, -2) in Brain Injuries: in Vivo and in Vitro Studies

Wang, J.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Exploring the Regulatory Mechanisms of Ep2-Mediated Epithelial-Mesenchymal Transition in Esophageal Squamous Cell Carcinoma

Kuo, K.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

The Study of the Involvement of Micrornas in Pressure-Induced Initial Renal Fibrosis

Chen, T.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

CAAT/enhancer binding protein beta訊息路徑參與thrombin誘導人類肺部上皮細胞IL-8/CXCL8表現之研究

Chen, B.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology