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• To Clarify the Role of Neurosteroids Metabolism in Drug Resistance in Glioblastoma(1/3)

  Hsu, T.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Roles of the Hdacs/Sp1-Mediated Microrna-106b~25 Axis in Drug Resistance of Glioblastomas(1/3)

  Chen, R.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Calcitriol Modulates Cardiac Fibroblasts through Noncanonical Pathway of Receptor for Advanced Glycation End Products and Fibroblast Growth Factor Receptor Signaling: Implicated in Cardiac Fibrosis in Diabetes

  Lee, T.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular Insights into Ketogenic Diet on Cardiac Metabolic Disorders in Diabetic Cardiomyopathy

  Lee, T.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Thermal Behavior and Canal Systems Obturation Evaluation of a Novel Gutta Percha

  Hsien, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Nucleic Acid Amplification as the Initial Diagnostic Test in Patients Suspected of Having Pulmonary Tuberculosis

  Chiang, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Lncrna Lnchifcar–Hif1a Regulatory Network and Its Clinical Relevance in Oral Cancer Progression(1/2)

  Shih, J.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Smart Sleep Deprivation in Aging: Neurophysiological Investigations of Cognitive Improvements after Sleep Restriction

  Wu, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Mechanisms and Therapeutic Strategies of Pd-L1 Expression in Oral Cancers( I )(1/3)

  Lin, H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effect of Rice Bran Oil and Frying Rice Bran Oil Combined with Exercise Training on Physical Performance, Gut Microbiota, Fatty Liver Disease and Insulin Resistance in Postmenopausal Condition(2/3)

  Chiu, W.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies of Hispolon and Its Structural Analogues on Delaying Aging Process and Neurodegenerative Disorders in Vitro and in Vivo(2/3)

  Hou, W.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Secretogranin 3 in Autophagy, Insulin Receptor Internalization, and the Regulation of Insulin Sensitivity

  Wu, H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Efficacy Assessment and Mechanism Exploration of Kruppel-Like Factor 2-Targeting Intervention Strategy for Non-Small Cell Lung Cancer Therapy(1/3)

  Wu, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Neurovascular Dysfunction in Post-Stroke Cognitive Impairment(2/3)

  Hu, H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Characterization of Multiple Functions of Plzf in Brain Development

  Lee, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Betulinic Acid as a Potential Inhibitor of Ire1/Xbp1/Herp Axis Blocking Both Proliferation and Survival of Glioblastoma Cells(2/3)

  Lo, W.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Anti-Α9nachr/Anti-Polyethylene Glycol Bispecific Antibody to Enhance the Therapeutic Efficacy of Nano-Drugs against Breast Cancer( III )Development of Anti-Α9nachr/Anti-Polyethylene Glycol Bispecific Antibody to Enhance the Therapeutic Efficacy of Nano-Drugs against Breast Cancer( III )

  Chuang, K.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Cerebral Blood Flow Dysregulation in Aging, Mild Cognitive Impairment and Dementia--A Study of the Structure Integrity of Neurovascular Unit

  Hu, H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Novel Lifr Axis in Metabolism Unhinged and Neuroendocrine Differentiation of Prostate Cancer(2/3)

  Liu, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Evaluating the Long-Term Effect of Low-Dose Aspirin Use during Pregnancy on the Prevention of Cardiovascular Disease among Women after Delivery

  Wu, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of an Innovative Bispecific Engager Simultaneously Binding Pd-L1 and Cd28 to Reverse Immunosuppressive Tumor Microenvironment for Enhancing Anti-Cancer Efficacy of T Cell-Based Therapies

  Chuang, K.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Rice Bran or Fermented Rice Bran on Modulating Immunosenescence in High- Fat Diet-Induced Obese Aged Mice: Pre- or Post- Menopause and Andropause Mice Model

  Yeh, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Evaluation of Angiogenic and Osteogenic Differentiation Potentials of 3d Mesenchymal Stem Cell Spheroid Culture

  Feng, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Automated Design of Natural Products Laboratory(2/3)

  Lee, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study on the Use of Static Magnetic Field to Induce Mechanobiological Effects to Enhance the Killing Ability of Natural Killer Cell

  Huang, H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of an Optimal Electrical Stimulation System for Lower Urinary Tract Disorders after Spinal Cord Injury(2/2)

  Chen, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Aspm-Wnt Signaling in Hepatoma Cancer Stemness and Progression and the Development of the Related Nano- and Gene-Therapy

  Tsai, K. K.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effectiveness of Implementing Shared Decision-Making on Quality of Care among Patients with Lumbar Degenerative Diseases: a Cluster Randomized Controlled Trail(2/3)

  Hou, W.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Anti-Egfr×Anti-Fap Bi-Specific Targeting Antibody Combined with Irinotecan Encapsulated Liposomes for Pancreatic Cancer Therapy(2/3)

  Lin, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Drug Delivery by Nano Scaffold Improved Immature Testicular Tissue Graft Survival Rate -A Transgenic Mouse Model

  Chen, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Simultaneous Center-Periphery Neuroimaging for Data-Driven Rehabilitation Assessment of Fallers(2/3)

  Chan, W. P.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Aspm-Par-Pcp Signaling in Invasive-Cancer-Stem-Cell-Mediated Metastasis and Its Therapeutic Targeting(1/3)

  Tsai, K. K.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Galectins-Immune Signaling Reprograming in Atrial Remodeling and Arrhythmogenesis: a Novel Therapeutic Strategy for Atrial Fibrillation(2/3)

  Chen, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Unraveling the Underlying Mechanism of Spock1 in Melatonin Suppression of Breast Cancer Cell Transendothelial Migration and Metastasis

  Lee, W.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Dysmetabolic Iron Overload Syndrome and Testosterone Biosynthesis: Role of Fat and Iron Enriched Diet(2/3)

  Chang, J.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Proteogenomics Platform for Multiplexed Screening of Membrane Protein Mutations

  Han, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Thrombotic Vascular Mimicking Microfluidic Platform to Evaluate Detection and Therapy of Thrombosis by Using Nanomedicine Carrier

  Fan, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigating the Dynamic Change of Genotype and Phenotype in Circulating Tumor Cells and Its Clinical Significance in Cancer Progression

  Lee, H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Phosphodiesterase Isoforms Inhibitors on Atrial Arrhythmogenesis from Modulations on Fibroblasts Activity and Cardiomyocytes Electrophysiology(2/2)

  Huang, J.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigating the Effect of Chrna7-P38mapk Inflammatory Signaling Axis on Lipoprotein(A)-Induced Macrophage Polarization and Coronary Artery Spasm Development(1/3)

  Hung, M.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Prebiotics and Microbiota on Metabolites and the Alzheimer’S Disease-Related Biomarkers in the Mice Fed High-Fat Diet

  Lin, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Impact of Chromatin-Modifying Agents on the Tumor Differentiation and Mibg Uptake of Neuroblastoma

  Liu, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Building Smart Medical Information Mart for Neuro Intensive Care (Smart Minic)

  Lin, M.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Predictions of Therapeutic Effects of Zolpidem in Disorders of Consciousness Patients(3/3)

  Lane, T. J.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Machine Learning-Based Radiogenomics for Connecting Mr Imaging to Immune-Regulated Genes Expression in Glioblastoma(1/3)

  Chen, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討一氧化氮奈米載體釋放系統應用於眼腦血管與神經相關之藥理作用機轉與潛在生物效應-探討一氧化氮奈米載體釋放系統於藍光誘發之視網膜病變及相關的藥理或生物效應(3/3)

  Cheng, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Using Electronic Health Record and Personal Health Information to Develop Erythropoiesis Stimulating Agents(Esa) Smart Dosing Model for Hemodialysis Patients

  Huang, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Integrated Cognitive Rehabilitation and Prosthesis System for Dementia - Year 2-4 Continuation Research Plan (Including Development and Evaluation of Vision Artificial Intelligence Based Cognitive Prosthesis)

  Tani, J.

  8/1/19 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study of the Roles of Au-Rich Element (Are)-Binding Proteins and Alternative Polyadenylation on the Tumorigenesis of Human Colorectal Cancer(2/3)

  Liang, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of Genetic and Cellular Factors in Women with Endometriosis(3/3)

  Tzeng, C. & Kao, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology