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• Pharmacological Investigations of Phenylethanoid Glycosides in Blue Light and N-Retinylidene-N-Retinylethanolamine Induced Retinal Degeneration and Their Protective Effects in Retinopathy

  Cheng, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Traumatic Brain Injury Triggers Acute Lung Injury: the Priming Effects Underlying Subsequent Neurological Sequelae and Cross Organ Injuries

  Wang, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Traumatic Brain Injury 100%
  • Acute Lung Injury 69%
  • Adult Respiratory Distress Syndrome 16%
  • Brain Injuries 9%
  • Chemokines 9%

• Psychophysiological Effects of Lactobacillus Plantarum Ps128 in Patients with Major Depressive Disorder and High Level of Inflammation：A Pilot Study of 8-Week Open Trail

  Chen, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Lactobacillus plantarum 100%
  • Inflammation 95%
  • Gastrointestinal Microbiome 89%
  • Probiotics 77%
  • Permeability 62%

• Development of Efficient Immunoglobulin G Analytical Method for Investigating Autoantibody Biomarkers for Pancreatic Disease (Continuous Research)

  Tsai, I.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • autoantibodies 100%
  • biomarkers 65%
  • pancreatic diseases 64%
  • pancreatic neoplasms 58%
  • pancreatitis 53%

• 4d Printing Smart Biomedical Scaffold on Biomedical Application

  Shen, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Shape memory effect 100%
  • Scaffolds 93%
  • 3D printers 65%
  • Electric fields 36%
  • Graphene 31%

• The Effect of Wnt Signals and Programmed Cell Death on the Organization of Neural Circuit in Spinal Motor Neurons

  Kao, T.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Motor Neurons 100%
  • Wnt Receptors 73%
  • Ephrins 46%
  • Nerve Growth Factors 42%
  • Growth Cones 40%

• Development a Risk Scoring System for Predicting the Risk of Poststroke Epilepsy to Improve the Quality of Care among Patients with Stroke

  Chien, L.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Epilepsy 100%
  • Stroke 45%
  • Anticonvulsants 24%
  • National Health Programs 20%
  • University Hospitals 15%

• Using Dual-Energy Ct to Follow Carotid Plaque Change and Associated Carotid Stent Patency

  Chen, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Stents 100%
  • Atherosclerotic Plaques 48%
  • Cerebral Arterial Diseases 39%
  • Stroke 31%
  • Carotid Stenosis 26%

• 腦血流調控功能在腦血管疾病及神經退化性疾病的角色及應用

  Chiou, H.

  8/1/17 → 7/31/18

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Application of Static Magnetic Field in Salivary Gland Cell to Regulate Calcium Ion Influx to Improve Salivation for Treating Xerostomia

  Yang, K.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Magnetic Fields 100%
  • Xerostomia 91%
  • Salivation 79%
  • Salivary Glands 45%
  • Fluids and Secretions 39%

• Study of Reactive Dicarbonyl Species-Induced Epithelial to Mesenchymal Transition in Diabetes Exacerbating Pulmonary Fibrosis (Ii)－Clarification of Age/Rage-Independent Pathways and Analysis of Correlation with Clinical Outcome

  Hsieh, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pulmonary Fibrosis 100%
  • Epithelial-Mesenchymal Transition 72%
  • Pyruvaldehyde 49%
  • Receptor for Advanced Glycation End Products 30%
  • Glyoxal 27%

• The Research and Development Plans of Embodied Medical Humanity Education(The Practice)：Curriculum Design and Educational Action Research of the Medical Simulation Learning and the Clinical Practicum in Long-Term Respiratory Care

  Ho, S.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • curriculum 100%
  • simulation 72%
  • learning 62%
  • research and development 56%
  • expertise 45%

• Evaluating the Biological Characteristics and Clinical Significance of Circulating Tumor Stem Cells in Cancer Progression

  Chen, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Circulating Neoplastic Cells 100%
  • Small Cell Lung Carcinoma 29%
  • Preclinical Drug Evaluations 19%
  • Neoplastic Stem Cells 11%
  • Neoplasms 8%

• Interrelationships between Growth Trajectory, Pubertal Development and Childhood Atopic Diseases/Symptoms in a Longitudinal Cohort Study

  Chen, Y.

  8/1/17 → 10/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Growth 100%
  • Adiposity 95%
  • Puberty 48%
  • Menarche 37%
  • Taiwan 30%

• Ultra-Compliant Degradable Hydrogel-Based Bioelectrode Applied for Treating Peripheral Neural Injury

  Huang, W.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Tissue 100%
  • Substrates 49%
  • Moisture 40%
  • Electrodes 35%
  • Signal transduction 34%

• Mri Study on Trans-Neuronal Degeneration of the Thalamic Networks after Ischemic Stroke

  Chen, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Thalamus 100%
  • Stroke 96%
  • Thalamic Nuclei 52%
  • Cerebral Infarction 43%
  • Gait 38%

• A Novel Human Blood Plasma-Photosensitizer-Conjugated Nanocomplex for Selectively Killing Colon Cancer via Locally Photodynamic/Photothermal Therapy

  Chuang, E.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Cell Surface Marker 100%
  • Nanomaterial 75%
  • Plasma 74%
  • Growth Factor 70%
  • Nanoparticle 59%

• The Use of Organometallic Reaction in the Syntheses of Anticancer Agents.( I )

  Liou, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Antineoplastic Agent 100%
  • Chan-Lam Coupling 96%
  • Buchwald-Hartwig Cross Coupling Reaction 79%
  • Ullmann Reaction 76%
  • Alkynylation 75%

• The Role of Advanced Glycation End Products on Proliferation of Leiomyoma Cell and Stem Cell: in Vivo and in Vitro Study

  Hsia, S.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigating Risk-Prediction Screening Tool for Falls and Effective Intervention to Prevent Falls in Community-Dwelling Older Population

  Chan, W. P.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Gait 100%
  • Walking 71%
  • Independent Living 60%
  • Bone Density 52%
  • Accidental Falls 46%

• Investigation on the Role of Cytoskeleton Reorientation and Calcium Ion Transportation in Static Magnetic Field Induced Mesenchymal Stem Cells Proliferation

  Huang, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • magnetic fields 100%
  • mesenchymal stromal cells 48%
  • cell proliferation 33%
  • stem cells 28%
  • cells 20%

• Radiogenomics of Malignant Gliomas by Linking Physiological Mr Imaging, Histopathological Patterns, and Genetic Alternations: a Translational Study from Rat to Man

  Chen, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glioblastoma 100%
  • Glioma 51%
  • Biomarkers 36%
  • Multiparametric Magnetic Resonance Imaging 15%
  • Neoplasms 14%

• Aldose Reductase and Nf-Kb Signalings in Collagen Receptor Glycoprotein Vi-Mediated Platelet Autophagy: a Regulatory Mechinary of Endogenous Gaba in Anucleate Blood Cells

  Sheu, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Autophagy 100%
  • Blood Platelets 64%
  • Aldehyde Reductase 63%
  • gamma-Aminobutyric Acid 33%
  • convulxin 30%

• Impact of Electron-Transfer-Flavoprotein Dehydrogenase Mutation on Bioenergetic Metabolism and Muscular Differentiation in Vitro

  Kao, S.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Multiple Acyl Coenzyme A Dehydrogenase Deficiency 100%
  • Electron-Transferring Flavoproteins 89%
  • Mutation 24%
  • Energy Metabolism 19%
  • Fatty Acids 18%

• Nano-Scaffolds Enhance the Survival Rate of Immature Cryopreserved Testicular Tissue in Transplantation - Transgenic Mouse Model

  Chen, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • immatures 100%
  • tissue engineering 84%
  • image analysis 60%
  • spermatogenesis 55%
  • banking 51%

• Evaluating the Association between the Prolonged Use of Magnesium Sulfate in Tocolysis and the Risk of Fractures among Neonates and Infants

  Wu, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Magnesium Sulfate 100%
  • Tocolysis 45%
  • Pregnant Women 36%
  • Taiwan 25%
  • United States Food and Drug Administration 12%

• Establishment of Screening Platform by Novel Bio-Markers of Clinical Osteoporosis and Development of Taiwanese Native Plants in Bone Remodeling: in Vivo and in Vitro Study

  Lee, M.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Mechanisms Study of Fatty Liver Diseases: Investigations on Potential Druggable Targets

  Hu, O. Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Longitudinal Study on Learning Outcome through Early Clinical Exposure

  Tang, K.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • learning behavior 100%
  • identity formation 46%
  • student 43%
  • learning theory 42%
  • professionalism 41%

• A Preclinical Study of the Therapeutic Targeting of Inflammatory-Cytokine-Addicted Cancer Stem Cells in Advanced Pancreatic Cancer

  Tsai, K. K.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Association between Improved Nutritional Care and the Prognosis of Cardiovascular Disease for Hemodialysis Patients

  Yang, S.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Renal Dialysis 100%
  • Diet 54%
  • Cardiovascular Diseases 38%
  • Nutrition Therapy 24%
  • Nutrition Assessment 21%

• The Role of Inflammatory Gene Polymorphisms on Risk of Post-Stroke Vascular Dementia( III )

  Chiou, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Developing an Ankle Assessment and Rehabilitation System for Improving Proprioception and Coordination Performances of Paretic Ankle Joint Following Chronic Stroke

  Lin, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Proprioception 100%
  • Ankle Joint 79%
  • Stroke 43%
  • Sensory Feedback 32%
  • Ankle 29%

• To Study the Role of Sp1 in Cancer Drug Resistance( II )

  Chuang, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展國際級之「全方位復健研究中心」(第四年)：聚焦輔助科技與神經復健研究

  Chen, S.

  8/1/17 → 7/31/18

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Decellularized Lymph Node Scaffold Vaccine Seeded with Dendritic Cells for Inducing Specific Antitumor Immunity

  Liu, D.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Dendritic Cells 100%
  • Lymph Nodes 61%
  • Immunity 30%
  • Neoplasms 28%
  • Neoplasm Antigens 26%

• Effects of Iron and Onion Supplementation on Advanced Glycation End Products Metabolism in Obese Rat Model

  Chang, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • fatty liver 100%
  • iron 67%
  • onions 46%
  • metabolism 40%
  • advanced glycation end products 33%

• Development of the Fully Humanized Bispecific Antibody to One-Step Expand and Arm T Cells for Selective Tumor Therapy

  Chuang, K.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • T-Lymphocytes 100%
  • Muromonab-CD3 39%
  • Bispecific Antibodies 20%
  • Blood Cells 18%
  • Cell- and Tissue-Based Therapy 13%

• Pulse Modulation Special Chip(Asic) System for Quantitative Dna Gene Sequencing

  Liou, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study on Development of Pandemic Influenza Preparedness Framework and the Harmonization of It with Other International Regulations

  Tsai, F.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Formal Social Control 100%
  • Human Influenza 91%
  • Pandemics 79%
  • Global Health 48%
  • International Health Regulations 42%

• Cellular and Molecular Mechanisms with Epigenetic Regulation by Histone Deacetylation on Postopratetive Atrial and Pulmonary Vein Arrhythmogenesis

  Chen, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone Deacetylases 100%
  • Atrial Fibrillation 85%
  • Pulmonary Veins 63%
  • Calcium 44%
  • Heart Atria 40%

• The Oncogenic Role and Targeted Therapeutic Potential of Alpha 9 Nicotinic Acetylcholine Receptors on Breast Cancers: Emphasizing in Pre-Clinical Assessment of Biphasic Antibody Nano-Drugs in Xenografts( I )

  Chang, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Adaptive Evolution of Pseudomonas Aeruginosa Within Hosts

  Huang, T.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pseudomonas aeruginosa 100%
  • Cystic Fibrosis 70%
  • Pseudomonas Infections 44%
  • Whole Genome Sequencing 41%
  • Hospitalization 39%

• Study on the Roles of Unfolded Protein Response and Ubiquitin-Proteasome System in Radiotherapy Using Nanoparticle Drug Delivery in Triple-Negative Breast Cancer

  Chiu, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Triple Negative Breast Neoplasms 100%
  • tubacin 87%
  • Endoplasmic Reticulum Stress 51%
  • Nucleotide Aptamers 40%
  • Proteasome Endopeptidase Complex 38%

• New Strategy in Natural Product Research --- a Rapid Analysis and Rapid Activity Screening Platform

  Lee, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • screening 100%
  • bioactive compounds 99%
  • environmental protection 43%
  • endophytes 36%
  • animal models 31%

• Exploring of Statisical Method in Meta-Analysis Including Parameter Estimation and Hypothesis Testing

  Chen, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Medicine 100%
  • Standard error 95%
  • Statistics 95%
  • Pooling 61%
  • Combined Method 59%

• Novel Tumor Immunochemotherapy Utilizing Dual Delivery of Chemodrugs/Pd-L1 Sirna of Serum Albumin Nanocarriers Prepared by Facile One-Pot Reversibly Assembling Method

  Sheu, M.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the Roles of Npc2 in the Regulation of Hepatic Stellate Cells Activation and Liver Fibrosis

  Liao, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Liver Cirrhosis 82%
  • Cholesterol 41%
  • Down-Regulation 17%
  • Becaplermin 10%
  • alpha-Fetoproteins 9%

• To Develop, Verify, and Apply the Evaluation Tool of Ebm Education with Rubrics

  Wu, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • medicine 100%
  • evidence 57%
  • evaluation 39%
  • expertise 38%
  • fairness 16%

• Macroplastic and Microplastic Pollution in Taiwan$S Seafood and Coastal and River Environments

  Walther, B. A.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • seafood 100%
  • pollution 84%
  • river 42%
  • tourism 38%
  • wilderness 35%