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• b - Ministry of Science and Technology

  研究PKLR促進前列腺癌神經內分泌分化之代謝途徑及其治療角色(1/3)

  Liu, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 膠淋巴系統於混合型失智症之角色(2/2)

  Hu, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study of the Molecular Mechanism Underlying Psat1-Induced Cancer Metastasis

  Lin, Y.

  1/1/15 → 12/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Cellular and Molecular Mechanisms with Epigenetic Regulation by Histone Deacetylation on Postopratetive Atrial and Pulmonary Vein Arrhythmogenesis

  Chen, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• 山藥儲藏性蛋白質功能性月生月太之延緩衰老功能評估與機制探討(2/3)

  Hou, W.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以阿茲海默症模型細胞篩選與評估醣苷神經鞘醯胺衍生物之藥效

  Lin, Y.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Exercise Training on Sleep Disturbances, Anxiety, and Depression among Newly Diagnosed Elderly Lung Cancer Patients

  Lin, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討新型冠狀病毒棘狀蛋白S1誘導心臟電生理及結構性重塑之病理機制：治療新型冠狀肺炎引發心臟損傷之新契機

  Kao, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發可刺激胰島beta細胞增生之拮抗型BACE-2抗體以改善第二型糖尿病(1/3)

  Chuang, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies on the Carcinogenic Mechanisms of Glucose Transporters in Gastrointestinal Cancer Cells and Its Clinical Therapeutic Applications(2/2)

  Chen, L.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Functional Investigation and Development of Potential Inhibitors of Kinetochore Associated Proteins in Cisplatin Resistance Cancer Cells

  Chen, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• 結合當地資源的燒燙傷衛教成效評估研究：以柬埔寨學齡孩童為對象

  Tsai, F.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Confounding Factors Associated with Immature Testicular Graft Survival for Fertility Preservation - Transgenic Mouse Model

  Chen, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Relationship between Sleep and Memory in Alzheimer Animal

  Hu, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• End-of-Life Care for Elderly with Advanced Dementia in Long-Term Care Facilities

  Chang, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• 抗免疫監測點抑制因子PD1 與PDL1的嵌合抗原受體修飾性γδ-T細胞用於治療卵巢癌療效之探討

  Liu, C.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Oral Health and Interventions for Elderly in Long-Term Care Facilities

  Chang, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Reconstitution of Spermatogenesis from Testis Failure after Spermatogonial Stem Cells (SSC) Transplantation for Male Fertility Preservation---A Transgenic Mouse Model

  Chen, C.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Functional Peptides Derived from Yam Dioscorin on Anti-aging Activities and Related Mechanisms

  Hou, W.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study of the Roles of Au-Rich Element (Are)-Binding Proteins and Alternative Polyadenylation on the Tumorigenesis of Human Colorectal Cancer(2/3)

  Liang, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Establishment of Screening Platform by Novel Bio-Markers of Clinical Osteoporosis and Development of Taiwanese Native Plants in Bone Remodeling: in Vivo and in Vitro Study(3/3)

  Lee, M.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 可降解鎂基金屬玻璃做為運動醫學修復手術縫合錨釘之研究開發

  Chen, C.

  5/1/20 → 4/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Mass Spectrometry-Based Quantification Strategies for Onco-Proteogenomics Investigation of Cancer-Specific Mutated Proteins (2nd~3rd Year)

  Han, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討團體芳香療法對改善失智症主要照顧者身、心健康之成效

  Liu, F.

  7/1/19 → 2/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討ERO1α經由c-Met調控腫瘤細胞移動的分子機制

  Liang, Y.

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of a Novel Peptide-Nanoformulation as Eyedrop with Nox2 Inhibition Capacity for Prevent Sight-Threatening Blood Vessel Growth on the Surface of the Eye(3/3)

  Tseng, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the mechanisms of novel benzimidazole derivative in the sorafenib-resistance liver cancer cell

  Liao, Y.

  7/1/18 → 2/28/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 虛擬實境教材應用於病房護理人員、護理系學生改善化學治療操作知識、認知程度之成效探討

  Huang, T.

  7/1/18 → 2/28/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation on the Suppressive Mechanisms of Novel Anti-Glypican3 Antibody Drugs

  Yang, Y.

  8/1/14 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Polycrystalline Silicon Nanowire Field Effect Transistor Biosensor Using Lateral Oxidation of Silicon Technique and Its Improvement on Sensitivity

  Wu, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• 動物冠狀病毒抗體開發-抗豬流行性下痢病毒蛋白的抗體製備與定性

  Yang, Y.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討BHLHE22在子宮內膜癌生成之角色

  Huang, R.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Establishment of Screening Platform by Novel Bio-Markers of Clinical Osteoporosis and Development of Taiwanese Native Plants in Bone Remodeling: in Vivo and in Vitro Study

  Lee, M.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Clarify the Role of Neurosteroids Metabolism in Drug Resistance in Glioblastoma(1/3)

  Hsu, T.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 肝硬化患者疲倦與肌少症之症狀評估與管理

  Huang, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Roles of Genetic Polymorphisms for Susceptibility and Clinical Outcomes of Colorectal Cancer in Taiwanese Lynch Syndrome Families

  Yeh, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Toxicological Assessment of Air Pollution in the Vicinity of a Petrochemical Complex

  Chuang, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role of Ribonucleotide Reductase (Rnr) in Skeletal Muscle with Age: the Functionality of Rrm2b in Repair and Regeneration

  Chen, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 國際產學聯盟計畫III

  Lin, C.

  9/1/19 → 8/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Involvement of Il-21-Regulated Circulating Fibrocyte Activation in Chronic Obstructive Asthma( II )

  Lin, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Targeting Kdm4a in Prostate Cancer(III)(3/3)

  Kung, H.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研究新穎長鏈非編碼RNA LINAT在TGF-beta訊息動態及腫瘤惡化的角色(1/3)

  Chen, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 臺北醫學大學基礎研究核心設施共同使用服務計畫(1/5)

  Chang, H.

  1/1/21 → 12/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Using Cometing Risk Model for Death and Multi-state Stochastic Process for the Behaviour of Betel-quid Chewing and Smoking to Estimate the Potential Years of Life Lost Due to Betel Quid and to Estiamte the Impact of Qutiing Betel-quid chewing

  Yen, M.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• 補充營養?補充糖?初探市售兒童保健軟糖或口嚼錠行銷策略與成份含量

  Chen, Y. C.

  7/1/19 → 2/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Ways of Seeing, Remembering, and Forgetting in the 21st Century: Unreliable Narrators and Narrative Parodox in Julian Barnes’ and Ian McEwan’s Novels

  Tseng, C.

  5/1/17 → 4/30/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Mechanistic Investigation of Linc00963 on Promoting Lymph Node Metastasis and Drug Resistance through Abcb5 Regulation and Its Potential Theranostic Value during Oral Carcinogenesis

  Tsai, L.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Biomedicine and Health Innovations: What Role for Law in the Global Bio-Economy(1/5)

  Lee, T.

  3/1/19 → 2/29/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Trade, Economic Factors, Envrionmental Hazards, and Risks of Infant and Child Mortality in Developing Countries

  Chuang, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• 慢性肝病在台灣是一個極具挑戰性的臨床議題。肝纖維化的多重病原性是造成病患死亡 率增加的原因，而且肝纖維化往往會發展成肝癌。我們最近利用國民營養調查資料庫 (NAHSIT 2005-2008)分析國人血中鐵營養值標與代謝症候群的相關性.在全人口的分析 中，我們發現校正了血清發炎指標以及飲食的營養指標後, serum ferritin (鐵蛋白質) 高於最大三等分位的族群，得到代謝性症候群的危險對比值超過 1.6 倍. 目前並不清楚 過量的鐵蛋白質為何與代謝症候群的發生率有關。肝臟為重要的儲鐵器官但是臨床研究 也顯示過量的鐵質沉積與肝纖維化及肝癌有極大的相關性。血清中鐵蛋白質為反映體內 儲存鐵的生化質標。但是,發炎因子也會造成血清中鐵蛋白質的異常增加。證據顯示發炎 因子可以調控鐵蛋白質的基因表現量。但是慢性發炎如何造成鐵蛋白質代謝異常(組職 內沉積及釋放)? 血清中的鐵蛋白質又有何生理功能? 隨著國人代謝症候群及脂肪肝發生率的年輕化,這次研究的主題是以老鼠初代星狀肝細 胞來分析鐵蛋白質對內質網壓力機轉與肝纖維化的影響: 相關研究的主要目標為: 1. 釐清鐵蛋白質(serum ferritin)過量是否會造成星狀細胞內質網壓力增加與活化? 2. 何種鐵質(ferric, ferrous, ferritin, Apoferritin)較易增加內質網壓力? 3. 找出何種內質網壓力的轉錄因子 (ATF6,ATF4, XBP1 and CHOP)受到鐵質調控? 4. 分析鐵質誘導的內質網壓力機轉與肝臟纖維化的營響

  Chang, J.

  9/1/12 → 8/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology