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• b - Ministry of Science and Technology

  New Strategies of Parkinson’s Disease Treatment

  Chiang, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Parkinson Disease 100%
  • Neurodegenerative Diseases 60%
  • Transplantation 53%
  • Exercise 38%
  • Induced Pluripotent Stem Cells 33%

• Immunization with Tn Antigen Protects Adult Mice and Newborn Rats against Hyperoxia-Induced Lung Injury via Inhibition of Nuclear Factor-Κb Signaling Pathway

  Chen, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hyperoxia 100%
  • Lung Injury 54%
  • Tn antigen 28%
  • Bronchopulmonary Dysplasia 28%
  • Immunization 24%

• Effects of a Program of Mind-Body Interventions on Psychological Resilience, Vagal Tone, Emotional States, and Outcomes of Heart Failure

  Tsai, P.

  8/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Self Care 100%
  • Heart Failure 94%
  • Equipment and Supplies 66%
  • Psychological Resilience 58%
  • Anxiety 53%

• Construction and Application of Medical Image Database in Tmu Healthcare System( I )

  Huang, C.

  11/1/17 → 10/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Genetic Polymorphisms of Calcium Channel in the Risk of Breast Cancer

  Chang, W.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Calcium Channels 63%
  • Breast Neoplasms 60%
  • Genetic Polymorphisms 37%
  • Calcium 24%
  • Case-Control Studies 18%

• Social Interaction Discovery and Publicity Mining

  Chang, Y.

  11/1/17 → 10/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Machine learning 100%
  • Learning systems 69%
  • Linguistics 64%
  • Tuning 52%
  • Personnel 51%

• A Mind-Body Approach to Study Irritable Bowel Syndrome: Role of Psychological Distress, Effectiveness and Mechanisms of Mindfulness Training

  Tsai, P.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Mindfulness 100%
  • Depression 82%
  • Anxiety 79%
  • Self-Help Groups 49%
  • Urbanization 35%

• Investigation on the Effect and Mechanism of Static Magnetic Field Coupled with Magnesium Ion for Promoting Odontogensis and Migration of Wharton'S Jelly Mesenchymal Stem Cells

  Huang, H.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • magnetic fields 100%
  • stem cells 72%
  • tooth pulp 53%
  • mesenchymal stromal cells 47%
  • jellies 44%

• 以基因剪輯技術(CRISPR/Cas9)應用於費城染色體為標靶之慢性骨髓性白血病治療

  Lee, C.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of Inflammatory Microenvironment-Regulated Stemess in Glioblastoma

  Ko, C.

  10/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • CCAAT-Enhancer-Binding Protein-delta 100%
  • Glioma 34%
  • Gallbladder Neoplasms 10%
  • Neoplastic Stem Cells 8%
  • Glioblastoma 8%

• The Severity Model of Brain Damage: Examining the Blood-Brain Early Injurious and Protective Biomarker Panels That Relate to the Susceptibility and Tolerance Responses of Hypoxic Ischemia(II)(2/3)

  Huang, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Functional Role of Growth Factor-Induced Metabolic Enzymes Expression in Cancer Cell Anti-Oxidation and Drug Resistance

  Chang, W.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Epidermal Growth Factor 100%
  • Enzymes 83%
  • Neoplasms 82%
  • Drug Resistance 46%
  • Carcinogenesis 39%

• Characterize the E3 Ligase Activity of Znf179 and Its Effect on the Proteinopathies of Tdp-43 Protein

  Huang, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Ubiquitin-Protein Ligases 100%
  • Amyotrophic Lateral Sclerosis 47%
  • TDP-43 Proteinopathies 45%
  • Frontotemporal Lobar Degeneration 36%
  • Proteins 32%

• Pharmacological Investigations and the Study of the Potential Biological Effects of Nitric Oxide Releasing Nano-Carrier System in Blue Light Induced Retinopathy( I )

  Cheng, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Identify Whether Ion Conductance Dysfunction Is an Early Electrophsiological Biomarker of Polyneuropathy in Diabetic Patients: a Longitudinal Study of Nerve Excitability in Diabetic Patients

  Sung, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neural Conduction 100%
  • Diabetic Neuropathies 69%
  • Ions 24%
  • Biomarkers 19%
  • Polyneuropathies 17%

• Constructing Clinically Translatable Silica Nanohybrids to Eradicate Hypoxic Tumor Cells(2/2)

  Wu, S.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • tumors 100%
  • nanoparticles 70%
  • silicon dioxide 47%
  • tantalum oxides 43%
  • hypoxia 39%

• Application of Multi-Omic Approaches to Evaluate the Effects of the Exercise on Exercise Performance, Metabolism and Neuropsychological Function of Long-Term or Acute Sleep Deprivation(1/3)

  Tung, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Txnip in Skewing Alveolar Macrophages towards M1/M2 Polarization: Implication for the Pathogenesis of Chronic Obstructive Pulmonary Disease(1/3)

  Chen, C.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Islide - a Global Community E-Learning Online

  Li, Y. & Jian, W.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Microscopes 100%
  • Websites 89%
  • Education 88%
  • Medical education 77%
  • E-learning 68%

• To Study the Role of Pctk1 in the Progression of Colorectal Cancer and Molecular Mechanism (Continuation Project)(2/3)

  Wei, P.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Integrated Study of Clinical, Molecular Analysis, Mr-Based Radiogenomic, and Preclinical Trials for Precision Treatment of Atypical Teratoid/Rhabdoid Tumor (Atrt) in Children(1/3)

  Wong, T.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Genetic Polymorphisms of Calcium Channel in the Risk of Breast Cancer

  Chang, W.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Calcium Channels 63%
  • Breast Neoplasms 60%
  • Genetic Polymorphisms 37%
  • Calcium 24%
  • Case-Control Studies 18%

• Effects of Maternal Depressive Symptomatology on Pregnancy Outcomes and Newborn Development---How Is Paternal Psychopathology Involved?

  Chen, Y., Hsu, C., Lin, H. & Huang, K.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Mothers 100%
  • Psychopathology 77%
  • Newborn Infant 75%
  • Spouses 59%
  • Pregnancy Outcome 59%

• Integration of Research on Novel Antibacterial Mini-Implant

  Lin, C. & Ou, K.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • steel 100%
  • infection 96%
  • breakage 73%
  • titanium 67%
  • bacterium 65%

• NF-kB以及NF-kB repressing factor (NRF) 在慢性阻塞性肺疾病引發系統性發炎之角色探討(3/3)

  Lee, K.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Exploring the Potential Impact of Periodontitis on the Induction or Development of Parkinson’S Disease: Utilizing Platelet Lysate as a Possible Therapeutic Strategy(2/2)

  Chang, H.

  8/1/18 → 12/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Breast Cancer Early Detection and Post-Treatment Smart Healthcare Tracking Platform

  Lin, R.

  6/1/19 → 5/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Series of Studies Analyzing Exercise Behavior and Exploring the Effects of Interventions among Pre-Diabetes, Type 1, and Type 2 Diabetes

  Jeng, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Exercise 100%
  • Type 1 Diabetes Mellitus 27%
  • Type 2 Diabetes Mellitus 23%
  • Education 19%
  • Life Style 16%

• Application of the Combination of Decelluarized Extracellular Matrix Grafted by Graphene and Bone Marrow Aspirate Concentrates on the Healing of Partial Tear of Anterior Cruciate Ligament(3/3)

  Chen, C.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • anterior cruciate ligament 100%
  • bone marrow 53%
  • extracellular matrix 44%
  • concentrates 35%
  • graphene 28%

• Effects of Long-Term Exposure to Indoor Air Pollution and Indoor Air Quality Improvement on Cardiovascular Health in General Population

  Chuang, K.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigating the Oncogenic Roles of A9-Nicotinic Acetylcholine Receptor Variants on Breast Cancer( III )

  Ho, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Effects of Electroconvulsive Therapy on Health Services Utilization, Positive and Negative Syndrome, and Sleep among Psychiatric Patients

  Chung, M.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Electroconvulsive Therapy 100%
  • Facilities and Services Utilization 37%
  • Psychiatry 29%
  • Health Services 28%
  • Sleep 25%

• A Multi-Modal Investigation of Self-Consciousness in Major Depressive Disorder(2/3)

  Lane, T. J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study of Nano-Size Memberane Tube for Tendon to Bone in Anterior Cruciate Ligament Reconstruction

  Chen, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role and Molecular Mechanism of Pparα in Acute Kidney Injury: Focus on the Protective Effect in Renal Tubular Cell

  Hsu, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Type C Phospholipases 73%
  • Kidney 56%
  • Acute Kidney Injury 37%
  • Gentamicins 27%

• Biomechanical Comparison of Warm-Up Strategies for Preventing Achilles Tendon Injury

  Chen, H.

  8/1/16 → 8/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Achilles tendon 100%
  • tendons 65%
  • risk factors 18%
  • mechanical creep 17%
  • torque 10%

• Effects of Different Oils Combined with Lycium Barbarum Extract on Chemical-Induced Liver Inflammation and Fibrosis in Rats

  Chao, J. C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Olive Oil 100%
  • Stellate Crystal 89%
  • Signal Transduction 47%
  • Antifibrotic 37%
  • Apoptotic 25%

• Longitudinal Dynamic Proteomic Analysis in Fibromyalgia Patients

  Kang, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fibromyalgia 100%
  • Proteomics 70%
  • Body Fluids 16%
  • Saliva 15%
  • Human Body 14%

• Contribution of ER Stress to Inhibit miR-19a/b and miR-26b-Mediated CTGF Expression in Lung Fibrosis (III)

  Chen, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Further Investigation of Drugs Resistance Mechanism in Lung Cancer with Lung Fibrosis

  Chang, C.

  1/1/18 → 12/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Lung Neoplasms 100%
  • Lung 97%
  • Fibrosis 93%
  • Adenocarcinoma of Lung 60%
  • Proto-Oncogene Proteins c-met 38%

• Radiogenomic Mapping of Angiogenesis in Glioblastoma

  Hsieh, K. L.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glioblastoma 100%
  • Phenotype 30%
  • Survival 28%
  • Multiparametric Magnetic Resonance Imaging 23%
  • Genetic Profile 21%

• Changes in Cognitive Functions in Patients with Recovery Stage of Traumatic Brain Injury: Effects and Mechanism of Neurofeedback(2/3)

  Chiu, H.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 為腎臟替代療法患者建立永續發展的營養照護生態系統

  Yang, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Roles of Micrornas in Endothelin-1 and Hypoxia-Induced Ctgf Production

  Chen, Y.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Endothelin-1 59%
  • Hypoxia 31%
  • Fibrosis 29%
  • Lung 23%

• The Role of Galectin-3 in Ceacam6 Enhanced Egfr Signaling and Its Implication in Head and Neck Cancer Therapy

  Wu, M.

  8/1/18 → 7/30/20

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Carcinoembryonic Antigen 100%
  • Cell Adhesion Molecules 98%
  • Galectin 3 64%
  • Squamous Cell Carcinoma of Head and Neck 43%
  • Cetuximab 24%

• A Mind-Body Approach to Study Irritable Bowel Syndrome---Role of Psychological Distress, Effectiveness and Mechanisms of Mindfulness Training

  Tsai, P., Chang, C. & Chen, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Mindfulness 100%
  • Depression 82%
  • Anxiety 79%
  • Self-Help Groups 49%
  • Urbanization 35%

• Bone-Marrow-Derived Mesenchymal Stem Cells in Prostate Cancer-Induced Bone Remodeling

  Hsieh, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Adipogenic 100%
  • Osteogenic 37%

• Predictors of Improvement of Nonalcoholic Fatty Liver Disease in Morbidly Obese Patients Undergoing Bariatric Surgery(III)

  Kao, W.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Lycium Barbarum Polysaccharides and Capsaicin on the Healing of Ulcerative Colitis-Mechanisms of Antioxidation, Anti-Inflammation, Anti-Apoptosis, Analgesic Activity, Intestinal Permeability, Cytoprotection, and Microbiota Regulation

  Chao, J. C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Biochemical Role of Protein Phosphatase Pp4 in Regulating Immune Response during Sepsis

  Yang, F.

  12/1/19 → 11/30/20

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Toll-like receptors 100%
  • spermatozoa 86%
  • innate immunity 54%
  • proteins 50%
  • non-specific serine/threonine protein kinase 27%