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• b - Ministry of Science and Technology

  Neuroimage Biomarker of Thalamo-Cortical Network for Outcome Prediction in Mild Taumatic Brain Injury: a Translational Mri Research

  Lu, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Research and development of on-line incremental Learning schemes for Big Data Analytics in non-stationary environments

  Chiang, I.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Highly Efficient Vi Ral Pseudoparticle Platform for the Identification of Novel Hepatitis C Vi Rus Entry Inhibitors

  Lin, L. T.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Mass Spectrometry-Based Quantification Strategies for Onco-Proteogenomics Investigation of Cancer-Specific Mutated Proteins (2nd~3rd Year)

  Han, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Novel Human Blood Plasma-Photosensitizer-Conjugated Nanocomplex for Selectively Killing Colon Cancer via Locally Photodynamic/Photothermal Therapy

  Chuang, E.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 即時移動污染源自體排放超細懸浮微粒之車載毒性測試平台建立與應用評估

  Chuang, H.

  9/5/17 → 9/4/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Key Technologies for Tandem Hybrid Perovskite Solar Cells

  Chang, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Novel Roles of Aryl-Hydrocarbon Receptor ((AhR) on Epigenetic and Post-Translational Modification of Cell-Cycle Regulatory Genes and Enos in Vascular Endothelial Cells---The Therapeutic Potential of Resveratrol/Statins

  Juan, S. & Hwang, L.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular Mechanisms of Propofol-Involved Protection against Ischemia Brain Injuries 全文電子檔： 全文連結1

  Chen, T.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

• Relationships of One-Carbon Cycle Pathways with Psychopathology and Metabolic Abnormalities in Patients with Schizophrenia and Potential Intervention Strategy with 5-Methyltetrahydrofolate and Vitamin B12

  Chen, C., Huang, S. & Lu, M.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Synergistic Function of Netrin-1 and Ephrin Signals in Spinal Motor Axon Guidance

  Kao, T. & Hsieh, T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Platelet Nano-Scale Vesicles: Delivery Cargo Platform of Neuroregenerative Biomolecules to the Brain(I)

  Burnouf, T. P. R.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Saliva Alkaloids of Areca Nut or Tobacco, Inflammatory and Antioxidants Status and Oral Hygiene in Periodontitis Patients

  Huang, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• The integrated theraptic effect of the major components of Psidium guajava L. aqueous extracts (PE) (gallic acid, quercetin, EGCG, and rutin) combining with medical trials and control diets on the chronic kidney disease

  Chen, K. & Peng, C.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

• Increasing Cryopreservative Efficiency of Therapeutic Cells by Coupling a Strong Static Magnetic Field during Freezing Process

  Huang, H.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

• In Vivo and in Vitro Studies of Progesterone-Induced Anti-Angiogenesis

  Lee, W.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

• Relationship between Lumbar Vertebral Perfusion and Fat Marrow Content in Normal Subjects, Osteoporosis and Bone Metastases Using DCE-MRI and Fat-Water Separation

  Chan, W. P.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Emerging Mechanisms of Omega-3 Fatty Acids in Depression---The Effects of EPA and DHA on Chronic Stress, Neurogenesis and Neuroinflammation(3/3)

  Huang, S.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Environment-Sensitive Chitosan Nanomicelles for Ph-Jump Activation, Oxygen Evolution and Anticancer Drug Delivery

  Mi, F.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• MTHFR和TYMS基因多形性與茶攝取之間的交互作用對口腔癌發生風險的影響

  Yeh, C.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Circuits of IGF-1R and Niche Signaling (Hypoxia/Inflammation) in Stem Cell Transformation and Its Clinical Implication of Molecular Target Therapy (Model of Germline Stem Cells)

  Huang, Y.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

• Surface Adsorption of Nanomaterials in Applications for Gas Sensor and Catalyst

  Lin, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• 老年人輕度頭部外傷後身體活動與腦震盪症候群變化之相關性

  Chiu, H.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討張口受限患者的牙關緊閉與生活品質之關係

  Huang, T.

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Development, Implementation, Evaluation, and Promotion the Interprofessional Shared Decision Making in Holistic Care: Innovating a Blended Learning Environment with Artificial Intelligence (1/3)

  Hou, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigating the Effect of Chrna7-P38mapk Inflammatory Signaling Axis on Lipoprotein(A)-Induced Macrophage Polarization and Coronary Artery Spasm Development(1/3)

  Hung, M.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Dissected the role of alpha-7 nicotinic receptor in the prognosis and clinical therapy on gastric cancers

  Chang, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Establish and Evaluate a Rehabilitation Nursing Program for Patients Receiving Orthopaedic Surgery

  Lin, P.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

• Epigenetic Editing as a Novel Therapeutics for Gynecological Cancer

  Lai, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Sp1-Regulated Neurosteroidogenesis in Glioma Development

  Hsu, T.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role and Mechanisms of Metabolomics in the Outcome of Acute Ischemic Stroke

  Chi, N.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 太極對退化性關節炎的高齡者功能性體適能的影響

  Lin, C.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study on the Mechanism of Cross-Talk between Ahr and Autophagy, and Autophagy---Associated Physiological or Pathological Phenomenon on Vascular and Airway Systems (I)

  Li, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌是目前世界上女性癌症病患中為數最多的癌症之ㄧ。腺病毒蛋白type 5 E1A (E1A)和許多抗腫瘤作用有關，曾於多種癌症如乳癌、卵巢癌及頭頸癌之病患進行臨床基因治療試驗。許多的研究指出E1A具有多項抗腫瘤的功能，包括抑制腫瘤的發生、增加腫瘤細胞對於化療藥物的感受性以及減少腫瘤轉移的現象。腫瘤的轉移對於癌症患者的死亡率有極大的影響當然也包括了乳癌的患者。E1A於抑制腫瘤發展的過程中具有多重生物學上的意義，這也促使我們想要釐清E1A抑制癌症的機制。因此，我們對於了解E1A抑制癌症轉移相關的分子機制感到有興趣，並期望藉以作為未來改進乳癌病人臨床試驗的基石。我們初步的實驗結果顯示，E1A可以有效的抑制Glucose-regulated protein 78 (GRP78)這種已被廣泛報導和腫瘤惡化及轉移相關的蛋白的表現。 提出此研究計劃之目的在於詳細探討E1A所造成的抑制癌轉移作用中，GRP78所扮演的生物功能及其調控的機轉。為了達到此目的，我們將著重於E1A如何調控GRP78表現並進而展現對乳癌轉移的抑制作用。以下為此項研究計畫的四大主要目標： 目標一：探討GRP78在E1A所抑制之癌細胞移行及侵入作用中所扮演的角色 目標二：研究E1A抑制GRP78表現之分子機轉 目標三：於動物模式中驗證GRP78的表現對於E1A抗腫瘤作用的影響 目標四：探討GRP78及其相關分子的表現在乳癌病人的臨床重要性 完成以上的主要目標能夠幫助我們對於E1A之抗腫瘤轉移作用建立更加詳細的分子訊息傳遞機制。另外，藉由此研究計畫的新發現也許可以對未來發展癌症治療上提供更多具有潛力的標的物。

  Wang, W.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Assessing the Mechanism and Magnifying the Combined Effects of Exercise and Deep Brain Stimulation for Parkinson'S Disease

  Chen, K.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Application Study of Personalized Cognitive Training Machine for Older Adults with Mild Cognitive Impairment to Improves Their Memory, Responsiveness, Attention and Coordination

  Chou, K.

  11/1/19 → 10/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Serious games With Interaction That promote Cognitive Health（SWITCH）-探討互動式嚴肅遊戲促進認知健康之成效

  Chiu, H.

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研究慢性阻塞性肺病中調控發炎老化的新機轉: miR-1, miR-133及let-7c之負調控導致過度活化gp130-IL-6信號傳遞路徑(1/3)

  Su, B.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 自體免疫心肌炎引起心室心律不整及鈣離子調控失衡、粒線體異常與NLRP3/MIF發炎體訊息路徑活化之致病機轉及治療策略探討(1/3)

  Chen, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 應用人工智慧於評估牙體形態優劣之研究

  Shen, Y.

  7/1/19 → 2/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Evaluation and Management of Symptoms of Fatigue and Sarcopenia in Patients with Liver Cirrhosis

  Huang, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular Mechanisms of Secretory Rab Gtpase 3c in Promoting Colon Cancer Metastasis(3/3)

  Chen, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Statin Inhibits Pressured-Induced Rat Renal Tubular Cell Apoptosis and Tubulointerstitial Fibrosis

  Chen, T. & Chen, C.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies on the anti-islet hypertrophy and anti-osteoporosis constituents from Formosan Fern

  Hsu, F.

  8/1/13 → 12/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Lay Health Knowledge Research:Example of Infants and Children Dietary Supplement

  Chen, Y. C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Dissected the Role of Glucose-Regulated Protein 94 (GRP94),The Clinically Therapeutic Implication and Drug Development in Colon Cancer

  Wei, P. & Chang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role of Activating Transcription Factor 3 in the Protective Effect of Resveratrol in Cardiomyocytes

  Liu, J.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Toxicological Assessment of Air Pollution in the Vicinity of a Petrochemical Complex

  Chuang, H. & Lee, K.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation on Developing Novel Biomarkers and Treatments in the Patients with Fibromyalgia

  Kang, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Pathophysiology of Macrophage Migration Inhibitory Factor on Electrical and Structural Remodelings in Heart Failure-Induced Atrial Arrhythmogenesis(3/3)

  Chen, Y.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology