Find Research Projects

Search results

• b - Ministry of Science and Technology

  Study on the Roles of Unfolded Protein Response and Ubiquitin-Proteasome System in Radiotherapy Using Nanoparticle Drug Delivery in Triple-Negative Breast Cancer(3/3)

  Chiu, H.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Triple Negative Breast Neoplasms 100%
  • tubacin 87%
  • Endoplasmic Reticulum Stress 51%
  • Nucleotide Aptamers 40%
  • Proteasome Endopeptidase Complex 38%

• Therapeutic Evaluation Etanercept, a Tumor Necrosis Factor Antagonist, in Experimental Heatstroke

  Chang, C.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • heat stroke 100%
  • tumor necrosis factors 42%
  • therapeutics 32%
  • death 31%
  • animal models 18%

• Aza-PBHA , 透過調控芳香烴受體於糖尿病視網膜病變治療潛力機制探討(1/3)

  Cheng, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 在動物模式下發展穿顱干擾波電刺激新技術應用於中風膀胱功能障礙復健治療(1/3)

  Peng, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Functional Peptides Derived from Yam Dioscorin on Anti-aging Activities and Related Mechanisms

  Hou, W.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Peptide 100%
  • Antioxidant Agent 73%
  • Methylglyoxal 51%
  • Galactose 39%
  • Oxidative Stress 38%

• 台灣菸商之定價策略與菸品消耗-2011-2019 非菸稅引起的菸價上漲與其影響

  Sanna, M.

  9/1/20 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigating a key switch between immune-overactivation and tumorigenesis

  Chang, S.

  2/1/16 → 1/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• 榖胱甘月太硫轉移酉每參與乳癌致癌之分子機制探討(3/3)

  Wu, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of hypertonic dextrose water injection for supraspinatus tendinosis patients: analysis of clinical and sonographic presentation

  Huang, S.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Huntingtin-Associated Protein-Mediated Vesicular Trafficking Biomarkers in Neurodegenerative Diseases

  Lin, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Alzheimer Disease 100%
  • Microtubules 83%
  • Neurodegenerative Diseases 74%
  • Biomarkers 69%
  • Huntingtin Protein 62%

• Carbamylation Modification of Novel Synovial Fluid and Serum Proteins and Its Role of Anti-Carbanylated Protein Autoantibodies in the Clinic Association of Rheumatoid Arthritis Was Investigated

  Lin, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Rheumatoid Arthritis 100%
  • Protein Carbamylation 74%
  • Synovial Fluid 68%
  • Proteins 44%
  • Autoantibodies 41%

• Molecular Mechanisms of Propofol-Involved Protection against Ischemia Brain Injuries

  Chen, T.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Propofol 100%
  • Ischemia 76%
  • Brain Injuries 75%
  • Reperfusion 34%
  • Mitogen-Activated Protein Kinases 30%

• The Roles of Novel CCCH Zinc Finger Genes on the Regulation of Cell Proliferation and Inflammation

  Liang, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pyroptosis 100%
  • Apoptosis 69%
  • Genes 65%
  • Inflammasomes 60%
  • Cell Proliferation 58%

• 外科系醫學(一)學門規劃研究推動計畫

  Wu, C.

  1/1/13 → 12/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the Klf10 alters metabolic pathways in genetic-deficient mice and human pancreatic ductal carcinomas

  Chang, H.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • 1-(7-(2-hydroxyethyl)dodecahydro-3a-methyl-1H-benz(e)inden-3-yl)ethanone 100%
  • Metabolic Networks and Pathways 49%
  • Pancreatic Neoplasms 46%
  • Knockout Mice 45%
  • Insulin Resistance 40%

• Wnt/Tenascin Regulates Neurotrophin-Induced Neuronal Transdifferentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells in 2d and 3d Cultures

  Lai, W.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Mesenchymal Stem Cells 100%
  • Tenascin 82%
  • Stem Cells 63%
  • Nerve Growth Factors 40%
  • Neurons 30%

• Characterization of Molecular and Pathological Role of Hs 1-Associated Protein X-1(Hax-1) in Cisplatin Induced Nephorotoxicity via Hax-1 Conditional Knock out Mice

  Lin, H. & Chen, T.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Cisplatin 100%
  • Kidney 45%
  • Knockout Mice 31%
  • Renal Insufficiency 22%
  • Wounds and Injuries 16%

• To Study the Role of Slc35b4 in the Progression of Colorectal Cancer and Molecular Mechanism

  Chang, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Longitudinal Cohort Study on Child Injury Using an Ecological Model of Injury across the Life Course

  Chen, P.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以新穎mito-FD-CRISPR/Cas9系統開發粒線體基因編輯模式

  Lee, C.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討第五型驅化物在糖尿病影響中風後所導致的血管性失智症中扮演的角色-(2)

  Chou, S.

  8/1/20 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 策略訓練對於提升獲得性腦傷患者執行功能的成效(2/3)

  Chang, F.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 抑制site-1蛋白酶引發肝癌細胞自我吞噬之研究

  Yang, P.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Effects of LED Light on Porphyromonas gingivalis in Periodontitis for Anti-Inflammation and Alveolar Bone Regeneration

  Deng, W.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Porphyromonas gingivalis 100%
  • Light 81%
  • Bone Regeneration 64%
  • Inflammation 47%
  • Alveolar Bone Loss 46%

• Copy Number Alterations and Transcriptome Profile Analyses Reveal Genetic Determinants Contributing to Higher Paclitaxel-Resistance of Ovarian Clear Cell Adenocarcinoma

  Chang, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Clear Cell Adenocarcinoma 100%
  • Paclitaxel 91%
  • Transcriptome 22%
  • Cell Movement 20%
  • Signal Transduction 19%

• Integrated Research and Development of 3D Connex Bio-Factory System on Craniofacial Reconstruction Application of Oral Cancer (I)

  Ou, K.

  5/1/14 → 4/30/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Industrial plants 100%
  • Medicine 36%
  • 3D printers 35%
  • Tissue 30%
  • Patents and inventions 21%

• Emerging and Reemerging Zoonotic Parasitosis Caused by Fish-Borne Parasites: Health Risks Associated with Consumption of Fish

  Fan, C.

  1/1/18 → 12/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Mechanistic Investigation of Linc00963 on Promoting Lymph Node Metastasis and Drug Resistance through Abcb5 Regulation and Its Potential Theranostic Value during Oral Carcinogenesis

  Tsai, L.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Marker 100%
  • Biological Marker 25%

• Characterization of Glioblastoma Using Advanced Multimodal Small Animal Mr Imaging Techniques

  Liu, H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Multifunctionalized Nanoparticles for Delivery of Chemotherapeutic Agents to Triple-Negative Breast Cancer

  Chiu, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 評估以慢性病病人用藥經驗理論為基礎之藥病溝通策略：混合方法研究

  Chang, E. H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Cellular and Molecular Mechanisms of Nicotine and Nitrosamines Promote Tumorigenic Behaviors in Renal Cell Carcinoma (II)

  Cheng, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Renal Cell Carcinoma 100%
  • Nitrosamines 59%
  • Nicotine 43%
  • Nicotinic Receptors 19%
  • Neoplasm Metastasis 16%

• 山藥儲藏性蛋白質功能性月生月太之延緩衰老功能評估與機制探討(2/3)

  Hou, W.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Mobile Phone Use and Walking: An Observational Field Study of Pedestrians’ Risky Behaviours and Inattentional Blindness

  Pai, C.

  8/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pedestrians 100%
  • Walking 46%
  • Text Messaging 42%
  • Music 35%
  • Blindness 22%

• Lipid Raft Associated Signaling in Regulation of Osteoclast Activation in Inflammatory Arthritis

  Tsai, H.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Inhibition of IkB Degradation Reduces Collagen Production via Downregulation of Androgen Receptor Expression in Dihydropyridine-Induced Gingival Overgrowth Cells

  Lu, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Gingival Overgrowth 100%
  • 1,4-dihydropyridine 67%
  • Androgen Receptors 63%
  • Proteasome Inhibitors 38%
  • Collagen 24%

• Study on the Immuno-Modulatory Effects of Notch Ligand Delta 4 on Immune Cells and in Ova-Induced Asthmatic Mice

  Lee, Y., Leu, S. & Liu, H.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Dendritic Cells 100%
  • Ligands 43%
  • Asthma 39%
  • STAT4 Transcription Factor 34%
  • Th2 Cells 23%

• Crowdhealth Project: Using Health-Related Big Data for Supporting Policy Making Decisions

  Shabbir, S. A.

  4/1/19 → 3/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies on the Mechanisms of Histamine N-Methyltransferase (Hnmt)-Mediated Herceptinr Drug-Resistance in Breast Cancer Cells

  Ho, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histamine N-Methyltransferase 100%
  • Trastuzumab 89%
  • Breast Neoplasms 17%
  • Tissue Array Analysis 9%
  • Gene Expression Profiling 8%

• Development of Novel Nanocomposite Films and Doping Techniques for Improving the Practicality of Flexible Perovskite Solar Cells

  Chang, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Solar Cell 100%
  • Encapsulation 66%
  • Liquid Film 55%
  • Nanocomposite 50%
  • Transmittance 38%

• Development a Tissue-Like Block by Novel Porous Calcium Phosphate Combined Dental Pulp Stem Cells and Platelets Rich Fibrin for Bone Regeneration in Large Bony Defect

  Lee, S.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Calcium phosphate 100%
  • Stem cells 80%
  • Pulp 61%
  • Bone 54%
  • Platelets 43%

• The Evolution of Active Intracranial Atherosclerotic Plaques after Stenting - an Observation Using Mr High Resolution Vessel Wall Imaging

  Chen, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Atherosclerotic Plaques 100%
  • Arteries 71%
  • Endothelial Cells 70%
  • Antioxidants 35%
  • Anti-Inflammatory Agents 35%

• Effects of N-3 Polyunsaturated Fatty Acids on the Gut Microbiota in Depressive Disorder

  Huang, S.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role and Molecular Mechanisms of N-Α-Acetyltransferase in Driving Tumor Invasion and Metastasis of Osteosarcoma

  Chien, M.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • osteosarcoma 100%
  • gelatinase A 66%
  • metastasis 59%
  • neoplasms 30%
  • acetyltransferases 21%

• The Role of EGFR in Prostate Cancer Progression and Combination Therapy(2/3)

  Liu, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Prostatic Neoplasms 100%
  • ErbB Receptors 82%
  • Berberis 26%
  • Neoplastic Stem Cells 16%
  • Neoplasms 15%

• Effects of Dietary Advanced Glycation Endproducts on Hypothalamic-Pituitary-Ovarian Axis in vitro and in vivo Study Are Associated with the Development of Polycystic Ovarian Syndrome: The Mechanisms of Action(1/3)

  Hsia, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Advanced Glycation End Products 100%
  • Polycystic Ovary Syndrome 69%
  • Granulosa Cells 14%
  • Diet 11%
  • Hormones 8%

• Effects of Nutrients Supplementation on Damaged Mitochondria and Their Biogenesis and Turnover

  Hsieh, R.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • biogenesis 100%
  • mitochondria 73%
  • nutrients 32%
  • animal models 28%
  • organelles 27%

• Trajectories, Predictors of Return-to-Work, and the Impact of Return-to-Work in Predicting the Quality-of-Life among Workers with Traumatic Limb Injuries

  Hou, W.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • worker 100%
  • quality of life 88%
  • rehabilitation 26%
  • hospital admission 22%
  • International Classification 20%

• Pupillometry in Vision, Arousal and Cognition: an Integrated Approach Using Oculomotor and Autonomic Responses, Brain Stimulation, and Computational Modeling(1/5)

  Wang, C.

  2/1/20 → 1/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pupil 100%
  • Arousal 61%
  • Locus Coeruleus 29%
  • Cognition 19%
  • Alzheimer Disease 19%

• Psychophysiological Effects of Lactobacillus Plantarum Ps128 in Patients with Major Depressive Disorder: a Pilot Study of 8-Week Open Trial

  Chen, C.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Lactobacillus plantarum 100%
  • Probiotics 77%
  • Gastrointestinal Microbiome 71%
  • Inflammation 53%
  • Permeability 46%