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  新穎性選擇性HDAC抑制劑之抗癌藥物開發與藥理機轉探討(3/3)

  Pan, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 闡明Hiltonol為主的複合式用藥在肺癌生長，轉移和腫瘤微環境中的作用。

  Chang, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討TCF7L1對前列腺癌神經內分泌分化之分子機轉與臨床意義

  Wen, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Glyoxalase 1 基因控制對肺癌惡性肋膜積水中代謝壓力介導產生的細胞上皮間質轉化與癌轉移的影響機轉(1/3)

  Chung, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• BSP相似重複序列家族蛋白在草綠色鏈球菌所引起的感染性心內膜炎中細菌逃避免疫攻擊及生物膜形成所扮演的角色及機制探討(2/3)

  Jung, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展三功能抗體(EGFR/CD3/mPEG)修飾之聚乙二醇-免疫增敏奈米藥物以主動標靶毒殺大腸癌並同時強化體內T細胞於腫瘤微環境抗癌功效之創新協同療法-開發三功能抗體(EGFR/CD3/mPEG)以協同加成聚乙二醇-免疫增敏奈米藥物及T細胞於大腸癌腫瘤微環境之抗癌功效(1/3)

  Lin, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌細胞α9尼古丁受體作為新穎靶向RNA奈米藥物與T細胞療法之臨床轉譯研究-開發抗α9尼古丁受體/抗CD3雙功能抗體以一步驟建構可高效標靶毒殺乳癌腫瘤之武裝型T細胞免疫療法(1/3)

  Chuang, K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討非選擇性與選擇性組蛋白去乙醯?抑制劑與免疫檢查點抑制劑合併治療之效用及其機轉(1/3)

  Huang, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 遠紅外線改善線粒體功能對糖尿病小鼠胰島β細胞的保護作用及與SIRT1和PLZF相關機制的研究(3/3)

  Chen, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 突觸支架蛋白Shank3調控神經發炎反應在急性缺血性腦中風之病理作用機制研究(2/2)

  Hsieh, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 非洲史瓦帝尼王國引致癲癇之神經性犬蛔蟲症或神經性囊尾幼蟲症之分子流行病學、相關危險因子與蟲體親緣分析(2020-2023)

  Fan, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討以網絡平台及個人化為基礎的認知行為治療方案 (Deprexis) 在台灣憂鬱症個案的成效: 隨機對照試驗(1/3)

  Chang, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌細胞受體專一性RNA適體奈米質粒誘發第三型玻尿酸合成酵素的抗癌機制探討(1/3)

  Tu, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 配對式神經調控模式應用於脊髓損傷者之前瞻神經復健技術開發-子計畫一: 在脊髓損傷動物模式下探討配對式神經調控之作用機制與療效(2/3)

  Peng, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 電漿活化水在綠色化學與神經醫學上的創新應用(3/3)

  Liu, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 透過感恩行為影響學生在大體解剖學實驗課程中的情緒感受與調適並強化家訪的效果

  Chiou, R.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 運用摺紙觀念暨四維列印於平面軟性材料之二維/三維形狀轉移

  Shen, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 殖民的味道：戰後臺灣的鰹節（柴魚）製作與消費文化 (1945-1995)(1/2)

  Tseng, L.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 奈米生物介面研究：中孔洞氧化矽奈米粒子性質及其蛋白質冠冕於抗聚乙二醇免疫性、腫瘤標靶效率及腎臟排泄的影響(2/2)

  Wu, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 癲癇精準醫療：基於腦連結體之頑性癲癇術後個體預測

  Peng, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 混合式案例學習法對於引發大學英語兼任教師群體反思之影響

  Lee, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 胃腸科相關癌症之差異蛋白質體與致病機轉之研究

  Lee, J.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the Effect of Dietary Tryptophan Supplementation Strategies in Parkinson’S Disease Progression and Tryptophan Metabolism with Plag6 Knockin Mice

  Huang, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• N-α-乙醯基轉移酶在調控去勢抗性的轉移性前列腺癌進展的新穎角色及其機制探討

  Lin, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 睪固酮和雄激素受體對於尿路致病性大腸桿菌誘發攝護腺發炎的作用及機制研究

  Ho, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• (教學實踐) AR 技術置入歷史課程教學對學生學習興趣之影響

  Tseng, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › d - Ministry of Education

• 探討以Myc/PD-L1/Akt作為治療惡性腦癌標靶之轉譯研究(3/3)

  Lin, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發透明質酸基奈米藥物以增強後眼部藥物遞送效能及應用於藍光誘導損傷之視網膜病變治療

  Tseng, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• (教學實踐) 數位敘事應用於大一英文課程：語言學習結合專業知能與學術能力之培養

  Fan, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › d - Ministry of Education

• 發展干擾染色質複製時期基因體穩定性之藥劑 (第二至四年)

  Lee, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 天然物實驗室的自動化設計(3/3)

  Lee, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌細胞α9尼古丁受體作為新穎靶向RNA奈米藥物與T細胞療法之臨床轉譯 研究-乳癌細胞α9尼古丁受體/HER2複合體作為RNA奈米藥物治療HerceptinR抗藥 性之機制探討(1/3)

  Ho, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 3D間葉幹細胞球體培養之血管和成骨分化潛能評估(2/3)

  Feng, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 次微米及奈米塑膠微粒的合成與其在海鮮中塑膠微粒檢測方法與毒性試驗的應用(3/3)

  Hsiao, I.

  8/1/20 → 8/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用結構生物學與蛋白質體學探討植物菌質體 PHYL1 交互作用蛋白質

  Wang, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 從食品風險暴露之角度探討非營養性甜味劑對女性生殖狀況之影響-非營養性甜味劑對子宮收縮及生殖細胞之影響效應及相關機轉探討(1/3)

  Hsia, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討 CWH43 大腸直腸癌發展的角色及其調控機制

  Chang, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以參功能抗體或雙功能抗體非共價鍵合至負載 Docetaxel 與 Pictilisib 協同組合量比之聚乙二醇化奈米載體而賦予雙標靶與阻斷功效以用於惡性與轉移性乳癌治療之療效加乘與規避耐藥性(3/3)

  Sheu, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 牙科用鈦植體表面製備具降解性鈣磷化合物並接枝含生長因子之奈米顆粒以促進其骨整合反應(3/3)

  Sun, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建立中風後失智疾病風險預測模式提升中風後照顧品質(2/3)

  Chien, L.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 陶斯松對於腸炎時CD4+ T細胞極化相關訊息路徑之影響(3/3)

  Hou, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討NPC2基因調控肝癌細胞內游離型膽固醇恆定在sorafenib抗藥性之角色(2/3)

  Liao, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討第一型內皮細胞分子與上皮細胞生長因子受體之相互調控在非小細胞肺癌進程之角色(3/3)

  Chien, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 幕友、幕僚與幕職的未竟之業：一項專業社會學的歷史考察(2/2)

  Tsai, P.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 活性維生素D經由非典型高等糖化終產物受體與纖維母細胞生長因子受體訊息調控心臟纖維母細胞與糖尿病心臟纖維化之關聯(3/3)

  Lee, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Tactile?massage改善長照機構老年住民孤寂、焦慮及憂鬱之成效探討

  Chuang, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 台灣藜、發芽台灣藜及發酵台灣藜對發炎性腸道疾病與大腸癌之抑制效果與作用機制

  Shih, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• RAB3C對大腸直腸癌之抗藥性與腫瘤免疫反應影響之探討(1/3)

  Chen, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 針對C型肝炎引發之肝細胞癌開發之溶瘤麻疹病毒精準醫療(3/3)

  Lin, L. T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 闡明SPOCK1/PI3K/AKT訊息路徑在透明細胞腎細胞癌對舒尼替尼抗藥性的潛在機制

  Lee, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology