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  β-catenin訊息路徑誘發動靜脈廔管病變之分子機轉: 預防動靜脈廔管狹窄之新型治療標的 (第二年延續計畫)

  Sue, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• P-選擇素調控具靶向多功能陰離子奈米載體包覆雙嘧達莫或白蛋白具有遠紅外光可觸發的熱療溫度/藥物釋放的聯合療法做為臨床應用(3/3)

  Chuang, E.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新穎性結構天然物萘醌衍生物於血管及淋巴管新生抑制與抗腫瘤之應用及其機轉探討(2/3)

  Huang, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Establishment, Effectiveness Evaluation and Learning Behavior Analysis of Contextual-Based Maternal Learning Environment Based on Knowledge-Based Expert System

  Chang, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討非營養性甜味劑對生殖系統之影響及可能作用機轉:從青春期到懷孕期-婦女攝取非營養性甜味劑對懷孕狀況之影響(2/3)

  Hsieh, R.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討ENO1/HMGB2調控多形性膠質母細胞瘤麩醯胺酸代謝重整及轉譯應用

  Liu, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 策略訓練對於提升獲得性腦傷患者執行功能的成效(3/3)

  Chang, F.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建立中風後失智疾病風險預測模式提升中風後照顧品質(3/3)

  Chien, L.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 轉錄因子Sp1在癌細胞抗藥性所扮演角色-HDACs/Sp1-microRNA-106b~25軸在膠質母細胞瘤抗藥性扮演的角色(3/3)

  Chen, R.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發可刺激胰島beta細胞增生之拮抗型BACE-2抗體以改善第二型糖尿病(1/3)

  Chuang, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 結合奈米診斷治療、影像免疫基因圖譜與人工智慧於原發性與再復發膠質母細胞瘤之研究-開發新穎結構小分子抑制劑用來抑制血管生成和腫瘤微環境以治療原發性及復發性多型性神經膠質母細胞腦瘤患者(3/3)

  Huang, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 計畫行為理論在決策輔助工具的做中學與藥師繼續教育

  Wang, L.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Metformin抑制TRPA1與P2X3受器所引發的呼吸反射及過度敏感之機制探討

  Lin, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 將BTK-ITK途徑作為標靶以克服肺癌治療的抗藥性以及抑制腦轉移的策略(3/3)

  Kuo, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 輕度腦外傷後白質損傷及修復: 新穎磁振定量影像和基因生物標記研究(1/3)

  Li, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 針對癌症治療研發與活性最適化蛋白質激酶抑制劑(3/3)

  Hsu, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 釐清神經類固醇的代謝在神經膠質瘤的抗藥性中扮演的角色(3/3)

  Hsu, T.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Post-Stroke Vi Sual Dependence and Early Intervention of Multisensory Balance Rehabilitation (3/3)

  Lee, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 柴油引擎廢氣粒子媒介嚴重氣喘氣道上皮層之肥大細胞活化與細胞激素釋放

  Weng, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 奈米控釋介導間質幹細胞外泌體合併細胞激素結合誘餌胜?與微囊蛋白-1支架領域胜?之三功能協同創新療法於治療肥胖併發敗血症所致器官傷害與死亡之療效: 聚焦細胞死亡相關機轉(1/2)

  Huang, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 後生元和益生菌透過抑制炎症和調節免疫力減輕新生小鼠高氧誘導的肺損傷

  Chen, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討芳香烴受體核轉位蛋白受器/丙酮酸去氫激?1路徑在與化療相關的頭頸癌進展所扮演的角色(2/3)

  Chang, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 抑制HIF-1α蛋白質促使線粒體運鐵蛋白功能恢復以改善棕櫚酸酯誘導的胰島素抗性

  Kuo, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討甜味受體在調控血糖衡定所扮演的角色(1/3)

  Wu, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Chemical Synthesis of Cancer-Associated Glycoproteins (II)

  Hsieh, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 「虛擬實境輔助解剖教學」對於超音波影像中週邊神經軌跡追蹤能力的成效評估: 疫情下對於超音波導引區域麻醉教學的因應與創新

  Lin, J. A.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 長期尿道出口阻塞透過膠原蛋白 I 沉積而降低膀胱順應性-針灸治療的潛在標的

  Lin, T.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• (教學實踐) 以虛擬實境方式強化[食品法規與管理]的實務應用教學

  Yang, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › d - Ministry of Education

• 艾克曼嗜黏蛋白菌和電漿活化水對硫酸葡聚醣鈉誘導的潰瘍性結腸炎的保護作用：從微生物代謝產物和蛋白質以及細胞外泌體中的小分子核醣核酸觀點出發

  Chang, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Aza-PBHA , 透過調控芳香烴受體於糖尿病視網膜病變治療潛力機制探討(2/3)

  Cheng, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以腸肝腦軸探討魚油對於長期攝取酒精大鼠腦損傷之影響：由脂質代謝及胰島素抗性、免疫發炎反應以及氧化壓力等途徑探討EPA和DHA的腦部保護作用(1/3)

  Yang, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研究細胞外基質膠原蛋白誘發的酸性微環境促進惡性膀胱腫瘤之角色功能探討(1/2)

  Lee, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討由中草藥丹蔘衍生之單一化合物及微小核糖核酸494在肥胖引發糖尿病導致腎病變之轉譯醫學研究

  Chen, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用藥物基因體發展急性登革熱病毒感染期間免疫反應之臨床診斷：探討T細胞組庫和C-型凝集素基因家族之遺傳變異(2/3)

  Chang, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發高效能人工光合作用系統(2/2)

  Kuo, T.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 抗伺機性與多重抗藥性金黃色葡萄球菌之犬蛔蟲重組胜肽之建構、表現和治療效果

  Fan, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 競爭性內源RNA-BC200調控網絡誘導腦瘤中嘌呤體形成之分子機制與臨床意義

  Lin, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 洗腎患者使用非類固醇抗發炎藥物與手術後併發症之相關性

  Lee, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 評估以奈米顆粒搭載抗新生血管藥物Aflibercept之眼藥水在小鼠角膜血管新生之治療效果

  Lin, I.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以機器學習和自然語言理解技術探勘社群互動關係及商業智慧之應用(2/2)

  Chang, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討具調節STAT訊息之真菌成分在視網膜穆勒及小神經膠細胞作用機制及其改善青光眼誘發神經性退化之療效(1/3)

  Hsiao, G.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 3D間葉幹細胞球體培養之血管和成骨分化潛能評估(3/3)

  Feng, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of blue-enriched white light therapy on sleep quality, depression, psychomotor vigilance, and symptom severity in patients with fibromyalgia (2/3)

  Tsai, P.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 肺阻塞表型分析與治療策略(1/3)

  Tseng, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the Effect of Dietary Tryptophan Supplementation Strategies in Parkinson’S Disease Progression and Tryptophan Metabolism with Plag6 Knockin Mice

  Huang, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Efficacy of “Tongue Strengthening Exercise and Shaker Exercise” on Swallowing Function, Tongue Strength, Aspiration, Risk of Malnutrition and Swallowing Quality of Life for Frail Elders with Mild Cognitive Impairment: a Randomized Controlled Study (2/3)

  Chou, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 三陰性乳癌之新生物標記暨標靶奈米載體開發

  Cheng, T.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以卷積神經網路、類神經網路、支持向量機、隨機森林及羅吉斯迴歸五者探勘技術預測肺癌病人鉑類藥物之腎毒性不良反應

  Chen, S. H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• CHRNA7-p38MAPKs axis發炎基因網絡在巨噬細胞極化作用及對脂蛋白(a)引發冠狀動脈細胞痙攣的機制探討(3/3)

  Hung, M.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 子宮內膜間質肉瘤之分子機轉及生物標記研究

  Kao, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology