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  Translational Studies of Mycobacterium Tuberculosis-Induced Lung and Pleural Fibrosis

  Lin, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Study on Trans-Neuronal Striato-Nigral Degeneration-Induced Movement Disorders after Stroke: Evaluation with Grey Matter Suppression Ir and Diffusion Tensor Imaging( I )

  Chen, C.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Novel Development of Continuous Bladder Volume Measurement System

  Chen, S.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Childhood Sleep Deprivation on the Development of Emotional Control and Cognitive Function of Prefrontal Cortex

  Chang, H.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Macro and Micro Biomechanical Studies of Soft Tissue Remodeling under Tissue Expansion (II)

  Chen, H.

  8/1/12 → 1/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Real-Time Single-Cell Probing of the Spatiotemporal Regulation of Cancer Cell Chemotaxis Using Nano-Scale Biomedicaltechnologies

  Yang, T.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Islide - a Global Community E-Learning Online

  Li, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Fish Oil on Alcoholic Liver Disease in Rats Based on Pathological Mechanisms

  Yang, S.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role and Molecular Mechanism of Pparα in Acute Kidney Injury: Focus on the Protective Effect in Renal Tubular Cell

  Hsu, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Essential Oils on Smooth Muscle Contraction in Rat Uterus (Gm07)

  Hsia, S.

  8/1/12 → 12/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Therapeutic Strategies for Traumatic Brain Injury with Novelly Desinged Drugs( I )

  Wang, J.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• NF-kB以及NF-kB repressing factor (NRF) 在慢性阻塞性肺疾病引發系統性發炎之角色探討(3/3)

  Lee, K.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Targeted Cancer Agents Using a Naturally Occurring Scaffold and Knowledge-Based Design

  Huang, W.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Renoprotective Mechanisms of Soy Protein in Rats with Diabetic Nephropathy

  Chen, J.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Study of the Relationships among Anti-Obesity Activity, Adipogenesis, and Adipose Angiogenesis of Vegetable Indolic Derivatives – Involvement of the Ah Receptor/Arnt ?

  Chen, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Translational Genomic Approaches in Endometriosis

  Tzeng, C., Kao, S., Huang, Y., Yang, W., Yang, W., Yeh, C., Li, Y. & Shen, S.

  8/1/12 → 10/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Depression Trajectories in Women – a Developmental-Ecological Approach (Gm03)

  Kuo, S.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies of Cxcl12 in Hypoxia-Induced Pulmonary Fibrosis

  Chen, B. & Chung, C.

  8/1/12 → 7/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Studies on the Anti-Islet Hypertrophy and Anti-Osteoporosis Constituents from Formosan Fern

  Hsu, F.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Targeting Hif-1α by Zebularine for the Treatment of Colorectal Cancers

  Yang, P.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Evaluation of the Effects of Selective Serotonin Reuptake Inhibitor on High Grade Glioma

  Shen, S.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Roles of Genetic Polymorphisms for Susceptibility and Clinical Outcomes of Colorectal Cancer in Taiwanese Lynch Syndrome Families

  Yeh, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Design and Development of Antibody-Targetable and Self-Assembled Micelles of Anticancer Drug Conjugate and Complex of Hyaluronic Acid

  Sheu, M.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Huntingtin-Associated Protein Related Biomarkers in Neural Survival

  Lin, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• 包載9α-型尼古丁乙醯膽鹼受體抑制劑之標靶性微脂體劑型設計與開發

  Sheu, M.

  8/1/12 → 7/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

• The Role of Cd69 in Tnfalpha-Inhibited Erythroid Differentiation

  Huang, H.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the Role of the Endoplasmic Reticulum Stress Related Proteins, Glycoprotein 96(Gp96), in Liver Cancer Progression and Metastasis and the Clinically Therapeutic Implication

  Huang, M.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Exploitation of Taiwan Native Plants in Promoting Bone Growth and Establishment of the System Biology Platform

  Lee, M.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Characterization of Molecular and Pathological Role of Hs 1-Associated Protein X-1(Hax-1) in Cisplatin Induced Nephorotoxicity via Hax-1 Conditional Knock out Mice

  Lin, H.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Pathogenic Role of Posttranslational Modification of Plasma N-Linked Glycoprotein to Rheumatoid Arthritis Combined Sjogren$S Syndrome Was Investigated

  Lin, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of DDX3 in Human Papillomavirus-Infected Lung Tumorigenesis

  Lee, H.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• 抽菸、α9-型尼古丁乙醯膽鹼受體、表皮生長因子受體及動情激素相關基因與乳癌之分子流行病學研究

  Chiou, H.

  8/1/12 → 7/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Association Study of Rare Variants and Disease in Case-Parental Data with One of Parents Missing

  Chen, J.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Novel Roles of Arnt in Breast Tumor Progression, Metastasis and Therapy

  Chang, W.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular Mechanisms of Alpha 9-Nicotinic Acetylcholine Receptor (Alpha 9-Nachr)-Mediated Trastuzumab (Herceptinr) Drug Resistance in Breast Cancer Cells

  Ho, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Effects of Atherosclerosis Progression in Circulating Ferritin in Community-Based Population

  Bai, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Roles of Micrornas in Endothelin-1 and Hypoxia-Induced Ctgf Production

  Chen, Y.

  8/1/12 → 7/31/14

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Role of Sp-Family in Lung Tumorigenesis

  Chang, W.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Functional Role of Transcription Factor Sp1 in Brain Neuronal Injury( I )

  Chang, W.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• 「智慧生活跨領域基礎課程與服務學習課程推廣計畫」-可攜式行動保健裝置暨個案健康評估管理資料庫服務學習課群擴散計畫

  Chiu, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › d - Ministry of Education

• Integration of Research on Novel Antibacterial Mini-Implant

  Lin, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• 環境正義視野下的流域治理：石門水庫集水區上游泰雅族部落永續發展策略之行動研究－石門水庫集水區整治之 政策分析：一個環境治理的觀點(III)

  Lin, Y.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• 依療法律與醫學倫理

  Ho, J.

  8/1/12 → 1/31/13

  Project: A - Government Institution › d - Ministry of Education

• 睡眠困擾是癌症病人最常主訴的問題之一。患有睡眠困擾之癌症病人經常同時伴隨 疲憊、憂鬱等現象發生，形成症狀群集，影響生活品質。雖然目前對於癌症病人睡眠障 礙之量性研究已多有著墨，然而對於癌症病人經歷睡眠障礙之主觀經驗之瞭解，仍相當 有限。瞭解病人經歷睡眠障礙之主觀經驗，將有助於未來睡眠評估工具之修訂。另外， 在評估癌症病人睡眠品質時，若能以簡單工具評估，會更具效率及助益。阿森斯失眠量 表(Athens Insomnia Scale, AIS) 是一個簡單的8 題問卷，廣為使用在一般失眠的病人， 在癌症病人使用上，尚未有豐富的實證資料，若能建立其在癌症病人的信效度，將可作 為一簡單篩檢癌症病人失眠的工具。 睡眠遵行日夜節律規則，日夜節律又需要光作為矯正的線索，光在癌症病人睡眠的 角色，尚未有研究證實，過去研究顯示癌症病人睡眠品質不佳與生物節律有關係。光是 重要日夜節律的線索，光療法透過褪黑激素調節，調整日夜節律週期，可能可以改善睡 眠品質。另外，由於，睡眠障礙、憂鬱、疲憊經常形成一症狀群集，光療法於改善睡眠 障礙之同時，是否亦同時改善憂鬱、疲憊及生活品質。目前，光療法在癌症病人的運用 上，付之闕如，故建立光療法於癌症病人的有效性值得探究。 本研究為三年期研究計畫，目的包括有：1.瞭解癌症個案對於睡眠困擾的主觀經驗 （第一年）。2.建立阿森斯失眠量表中文版的信效度、敏感性、特異性（第一年）。3.瞭 解癌症病人光暴露與生物節率、睡眠障礙的關係（第二年）。4.瞭解光療法對於改善癌 症病人睡眠障礙及相關症狀群集、及生活品質之成效；以及瞭解光療法影響褪黑激素之 程度（第三年）。 本研究擬以癌症住院及門診病人為對象，研究工具包括基本資料、匹茲堡睡眠品質 問卷、阿森斯失眠問卷，簡明疲憊量表，貝克憂鬱量表度、SF-36 生活品質量表、腕動 力器等。資料處理分析方式包括：內容分析、描述性統計、t 檢定、皮爾森相關、GEE (generalized estimating equations)等。 本研究之結果將可瞭解光暴露與生物節率與睡眠障礙之間的關係，並可進一步瞭解 光療法作為改善癌症病人睡眠障礙之護理措施之成效，以期，最終能藉由改善癌症病人 之睡眠品質提昇病人之生活品質。

  Lin, C.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Modulation of Tumor Microenvironment by Nucleic Acid Chimeras as a New Paradigm for Adjuvant Cancer Therapy

  Yeh, S.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Roles of Toll-Like Receptor-4 and Hif-1 in Propofol-Involved Protection against Traumatic Brain Injury-Induced Dysfunction of the Blood-Brain Barrier

  Chang, H.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Preceptors’ Perceptions of Training Programs and Training Needs, Experienced Barriers during Precepting, and Development and Effectiveness Evaluation of a Preceptor Intervention

  Chang, W.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Avoidable Hospitalizations and Primary Care Manpower in a Universal Health Insurance System: a 15-Year Trend Analysis

  Huang, K.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Analysis the Role of Satellite Cell during Denervation Induced Muscular Atrophy and a Trail of Transplantation of Adipocyte Derived Myogenic Stem Cells.

  Chang, H.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Build of Functional Protein Molecular Shuttles by Using a Genetically Engineered Kinesin and Nucleic Acid Aptamers - with the Integration of the Cost-Effective Microscopic Imaging System and Micro Fluidic Channel Chips

  Kuo, T.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology