Find Research Projects

Search results

• 探討發酵米糠之補充對腸道菌生態及腸道黏膜免疫系統之芳香烴受體路徑之影響：以葡聚糖硫酸鈉引致之腸炎小鼠為模式(2/3)

  Yeh, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 單側唇腭裂患者的鼻道阻塞的評估與治療2(2/2)

  Chen, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Aza-PBHA , 透過調控芳香烴受體於糖尿病視網膜病變治療潛力機制探討(2/3)

  Cheng, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 甜蜜的戰爭二部曲:含糖飲料與網路的誘惑

  Chen, Y. C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 計畫行為理論在決策輔助工具的做中學與藥師繼續教育

  Wang, L.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 都市自然環境對心理健康、壓力與身體活動之影響：真實與虛擬體驗比較(2/3)

  Yen, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• The impact of technology-enhanced projected-based learning applied in Introduction to Research on self-efficacy

  Yen, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › d - Ministry of Education

• 枸杞多醣與辣椒素對潰瘍性結腸炎修復之影響-探討抗氧化、抗發炎、抗細胞凋亡 、止痛、腸通透率、細胞防禦及菌相調節機制(3/3)

  Chao, J. C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 在國際健康功能與身心障礙分類系統的架構下，探討蛋白質補充合併運動訓練對急慢性機構衰弱老人改善肌少症指數及身體活動功能之成效(3/3)

  Liou, T.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 撫觸療法改善長照機構老年住民心理健康及相關指標之成效探討

  Chuang, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 臺灣食用油與含油食品縮水甘油酯含量調查與形成機制研究(3/3)

  Lee, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發高效能人工光合作用系統(2/2)

  Kuo, T.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 多功能奈米載體攜帶化療藥物併用HDAC抑制劑於三陰性乳癌之應用

  Chiu, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• RAB3C對大腸直腸癌之抗藥性與腫瘤免疫反應影響之探討(2/3)

  Chen, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討在慢性腎臟疾病中經由抑制內皮素轉化?調節前列腺素E2受體和自體吞噬作用的治療潛力之機轉(2/3)

  Chiu, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發可刺激胰島beta細胞增生之拮抗型BACE-2抗體以改善第二型糖尿病(1/3)

  Chuang, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用藥物基因體發展急性登革熱病毒感染期間免疫反應之臨床診斷：探討T細胞組庫和C-型凝集素基因家族之遺傳變異(2/3)

  Chang, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發可標靶樹突細胞之負載新型冠狀病毒棘狀蛋白的醣化PLGA奈米顆粒在小鼠中引起有效的免疫原性之研究

  Sheu, M.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 絲氨酸/蘇氨酸蛋白激?(SIK3)參與乳癌致癌過程的分子機制探討

  Chen, L.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌細胞α9尼古丁受體作為新穎靶向RNA奈米藥物與T細胞療法之臨床轉譯研究-開發抗α9尼古丁受體/抗CD3雙功能抗體以一步驟建構可高效標靶毒殺乳癌腫瘤之武裝型T細胞免疫療法(2/3)

  Chuang, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 組織胺甲基化轉換酵素(HNMT)輔助臨床醫師鑑別乳癌病患作為Herceptin療效評估之新穎分子標記(3/3)

  Ho, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌細胞α9尼古丁受體作為新穎靶向RNA奈米藥物與T細胞療法之臨床轉譯研究-探討α9尼古丁受體基因表現在乳癌病人血液循環腫瘤細胞/游離DNA於乳癌治療的應用(2/3)

  Tzeng, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研究細胞外基質膠原蛋白誘發的酸性微環境促進惡性膀胱腫瘤之角色功能探討(1/2)

  Lee, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 預凝膠法合成之酸鹼應答型之磷酸鈣/海藻膠奈米藥物載體應用於膀胱癌的治療

  Liu, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發循環腫瘤細胞類器官晶片於大腸直腸癌藥物研發

  Chiou, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Glyoxalase 1 基因控制對肺癌惡性肋膜積水中代謝壓力介導產生的細胞上皮間質轉化與癌轉移的影響機轉(2/3)

  Chung, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 綿天膜中空纖維之高臨床相關性、快速及低成本藥物篩選平台應用於癌症免疫療法作為針對個人化醫療的免疫檢查點抑製劑 (PD-1 / PD-L1) 之伴隨診斷

  Chen, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 結合奈米診斷治療、影像免疫基因圖譜與人工智慧於原發性與再復發膠質母細胞瘤之研究-建立原發性和再復發膠質母細胞瘤免疫圖譜以及建立免疫療法(3/3)

  Lee, G.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以老藥利尿劑新用為抗骨肉瘤之藥物：利尿劑對於骨肉瘤細胞存活、爬行與代謝之影響

  Su, B.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 奈米控釋介導間質幹細胞外泌體合併細胞激素結合誘餌胜?與微囊蛋白-1支架領域胜?之三功能協同創新療法於治療肥胖併發敗血症所致器官傷害與死亡之療效: 聚焦細胞死亡相關機轉(1/2)

  Huang, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展三功能抗體(EGFR/CD3/mPEG)修飾之聚乙二醇-免疫增敏奈米藥物以主動標靶毒殺大腸癌並同時強化體內 T 細胞於腫瘤微環境抗癌功效之創新協同療法-發展新型聚乙二醇-免疫增敏奈米藥物載體以毒殺大腸癌並強化腫瘤區域T細胞之抗癌功效(2/3)

  Liu, D.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 護理人員減效出席之系列研究(1/2)

  Jeng, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 標靶整合素αvβ3-FAK訊號網絡的膽管癌診療策略開發-標靶膽管癌整合素αvβ3訊號網絡的新型診療性奈米微脂體DL-N2之研究(1/3)

  Lin, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌細胞α9尼古丁受體作為新穎靶向RNA奈米藥物與T細胞療法之臨床轉譯 研究-乳癌細胞α9尼古丁受體/HER2複合體作為RNA奈米藥物治療HerceptinR抗藥 性之機制探討(2/3)

  Ho, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 分析非典型趨化因子CCRL2 在癌症細胞器官專一性轉移及粒線體呼吸鏈上所扮演之角色

  Sung, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展三功能抗體(EGFR/CD3/mPEG)修飾之聚乙二醇-免疫增敏奈米藥物以主動標靶毒殺大腸癌並同時強化體內T細胞於腫瘤微環境抗癌功效之創新協同療法-開發三功能抗體(EGFR/CD3/mPEG)以協同加成聚乙二醇-免疫增敏奈米藥物及T細胞於大腸癌腫瘤微環境之抗癌功效(2/3)

  Lin, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 藉由研究腫瘤異質性來克服治療引發的癌細胞幹細胞特性及治療抵抗性(1/2)

  Lo, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 進展性胰臟癌新穎增進免疫療法的治療策略與生物指標-節拍式化學治療增進基質硬化性胰臟癌免疫監督與免疫檢查點阻斷療法: 聚焦於腫瘤基質與髓源性抑制細胞(3/3)

  Tsai, K. K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討低氧微環境腫瘤外泌體與發炎細胞激素IL-6於B型肝炎病毒誘導肝癌表現多能性幹細胞基因OCT4與TKI抗藥性之調控機制與其臨床意義

  Huang, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 在具放射治療抗性神經膠質母細胞癌的細胞中尋找MicroRNA (miR-671-5p)控其高細胞移動特性、癌症幹細胞特性及遠隔效應，並搭配人工智慧軟體開發基因調控資料庫加強免疫治療策略

  Lin, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新穎癌幹細胞侵犯腳治療標靶之整合性蛋白質體、基因體、小分子與功能篩選：聚焦細胞表面AMFR於侵犯性消化道癌症治療標的(2/3)

  Tsai, K. K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 奈米HEVnp於晚期大腸直腸癌患者的治療策略(3/3)

  Whang-Peng, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 正常子宮內膜BHLHE22亞型應用於子宮內膜癌分子分型之研究

  Liew, P.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 標題：謹慎設計抗胃癌藥物：結構簡化方法、骨架躍遷策略以及對二氧化矽負載的質子酸/路易斯酸催化的多組分反應以產生關鍵中間體的詳盡探索

  Nepali, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 結構優化苯丙炔醯胺基礎之蛋白質雙硫鍵異構酶抑制劑以作為具潛力之抗多形性神經膠質母細胞瘤試劑(1/3)

  Huang, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• CCR5標靶微脂粒包覆免疫抑制藥物Tacrolimus治療自體免疫疾病之研究(3/3)

  Liu, D.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討膠質母細胞瘤外泌體中Btk/PD-L1/PD-L2 訊號途徑在腫瘤免疫所扮演的致病角色及其精準治療應用

  Lin, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發1,3-二芳基取代之五元雜環作為抗胰臟癌劑(3/3)

  Lee, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 半乳糖凝集素-1調控TNFR1蛋白穩定性以促進肝癌進程之轉譯研究

  Wu, M.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 磷酸化Dicer蛋白調節微核糖核酸生合成及麩醯胺酸代謝轉變在胰臟癌吉西他濱抗藥性的作用

  Chiu, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology