Find Research Projects

Search results

• TMU102-AE1-B11

  Lee, C.

  10/1/13 → 9/30/14

  Project: B - Project of TMU › i - Other (Funded by TMU)

• TMU102-AE1-B12

  Wang, H.

  10/1/13 → 9/30/14

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Micro-Scale Surface-Enhanced Raman Spectroscopy in Real-Time Single Living Cell Diagnostics (I)

  Peng, P.

  10/1/13 → 9/30/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• TMU102-AE1-B05

  Chen, S.

  10/1/13 → 9/30/14

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Niche Signaling Networks in Self-Renewal and Migration of Pluripotent Germline Stem Cells and Its Implication for Germline Differentiation in Human Pluripotent Stem Cells (III)

  Huang, Y.

  10/1/13 → 9/30/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• TMU101-AE1-B62

  Chuang, T.

  7/1/13 → 9/30/14

  Project: B - Project of TMU › i - Other (Funded by TMU)

• 事故傷害監測研究與決策支援先驅計畫

  Chen, P., Lin, M. & Shu Kei Lam, C.

  9/27/13 → 9/26/14

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 在缺血性中風病人其顱內外動脈狹窄程度與基質金屬蛋白酵素表現之相關性研究

  Hsieh, F.

  3/1/13 → 8/31/14

  Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital

• TELEDERMATOLOGY SOLUTIONS THOUGH MOBILE PHONE

  Li, Y.

  9/1/13 → 8/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Novel Strategies to Target Long-Lived Plasma Cells for Treating Hemophilia a Inhibitors

  Liu, C.

  9/1/13 → 8/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Disjunctivism and Theories of Action

  Lin, C.

  8/1/12 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Effect of Improved Nutrition Care on the Progress of Hemodialysis Patients

  Yang, S.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Novel Degradable Biomaterial for Dental Hemostatic Sponge Applications

  Lin, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• 設計並評估新型含藥人工骨凝膠對齒槽骨缺損的修復作用

  Lee, S.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• 《Understanding International Conflicts：An Introduction to Theory and History》Translation and Annotation Project

  Chang, K.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Community-based Screening and Prevention Model for Periodontal Disease

  Chen, L.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Assessment of Iron Status in Overweight and Obese Adolescents

  Chang, J.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigating the Differential Effects and the Mechanisms of Flavonols on Osteogenic Differentiation of Human Dental Pulp Stem Cells

  Lee, S.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Explore of Toll-Like Receptors Associated Mirna Expression in Ischemic Stroke Patients (I)

  Wu, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role of Sp-family in lung tumorigenesis

  Chang, W.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Physical Properties and Biocompatibility of Orthodontic Elastomeric Chain after Nanoimprint Surface Treatment

  Cheng, H.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Study on the Influence of Classical Mathematics Reading Course on Medical Students Beliefs about Mathematics

  Ying, J.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of fish oil on alcoholic liver disease in rats based on pathological mechanisms

  Yang, S.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study on the cancer and non-cancer, including cardovascular diseases, risks in cohort population with prolonged low-dose radiation exposure

  Chang, W.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Saliva Alkaloids of Areca Nut or Tobacco, Inflammatory and Antioxidants Status and Oral Hygiene in Periodontitis Patients

  Huang, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Moderating Effect of Welfare States on Health and Service Utilization - Comparison of Taiwan and European Countries

  Chuang, K.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Bullying Experience, Attitude and Suicide Attempts among Adolescents

  Chen, P.

  8/1/12 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• 山藥儲藏性蛋白質功能性月生月太之延緩衰老功能評估與機制探討(1/3)

  Hou, W.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Emerging Role That Splicing Factor Plays in the Adipose Development

  Lin, J.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Study of the Trismus Condition of Patients with Head and Neck Cancer Who Have Undergone Concomitant Chemoradiotherapy and the Preventive Effect of Oral Rehabilitation on Trismus

  Jeng, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• 大腸直腸癌已躍居世界上癌症死亡率第二名，屬於固體型腫瘤，缺氧常見於此類 腫瘤，並誘發HIF-1α 表現而導致抗藥性及預後較差，因此抑制HIF-1α 被視為新的抗 癌策略。Zebularine (Zeb)是較穩定之DNA methyltransferase (DNMT)抑制劑，可殺死癌 細胞而不影響正常細胞，對小鼠也不具毒性。我們初步結果顯示，Zeb 可抑制人類大 腸癌細胞株HCT116 之HIF-1α表現，代表Zeb 是治療大腸直腸癌之潛力藥物。我們的 初步也證明Zeb對HCT116具毒殺性，對小鼠大腸癌也有療效。細胞自我吞噬(autophagy) 是指細胞在惡劣環境下，經由吞噬細胞內物質產生能量渡過外界壓力的一種保護機 制；也有研究報導指出，藥物會誘導癌細胞產生autophagy，造成細胞過度吞噬其內容 物而死亡，因此，autophagy在癌細胞為保護或是引發毒殺作用，目前仍無定論。缺氧 也會透過HIF-1α 導致autophagy 而促進細胞存活，但嚴重缺氧或無氧狀態則可透過活 化AMPK及unfolded protein response (UPR)造成autophagic cell death。我們初步結果顯 示，除抑制HIF-1α 表現外，Zeb 也可活化AMPK、UPR/ER stress、以及autophagy， 因此我們推測Zeb 可在缺氧狀態下，促進autophagic cell death。3 年內我們將執行4 項 目標： (1) 探討Zeb 在各種癌細胞及活體模式之抗癌作用。（第一年） (2) 研究Zeb 抑制HIF-1α表現之分子機轉。（第一年到第二年） (3) 研究Zeb 誘發autophagy之分子機轉。（第二年到第三年） (4) 探討Zeb 對缺氧導致抗藥性之作用。（第三年）

  Yang, P.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Gender Analysis of Workplace Violence among Medical Care Personnel

  Chen, R.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Explore of Toll-Like Receptors Associated Mirna Expression in Ischemic Stroke Patients (I)

  Wu, C.

  8/1/13 → 7/31/14

  Project: B - Project of TMU › i - Other (Funded by TMU)

• 小客車路口闖紅燈、加速行為: 以kernel logit 模型估計行人倒數計時器之影響

  Pai, C.

  11/1/12 → 7/31/14

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• Real-Time Single-Cell Probing of the Action Mechanism of Amphotericin B Ion Channels---From Extracellular to Intracellular

  Yang, T.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討芳香烴受體(AhR)改變血管內皮細胞功能之新角色：經由表觀基因或後轉譯修飾(細胞週期蛋白/內皮細胞一氧化氮合成?)的調控與白蘆黎醇/史達汀臨床治療及應用(1/3)

  Juan, S.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Cellular and Molecular Mechanisms of Nicotine and Nitrosamines Promote Tumorigenic Behaviors in Renal Cell Carcinoma (Ii)

  Cheng, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Hospital Patient Safety Culture-Comparison of Major Measurement Tools, Promotion Methods and Their Evaluation

  Kuo, N.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Therapeutic Strategies for Traumatic Brain Injury with Novelly Desinged Drugs (II)

  Wang, J.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of a Computerized Adaptive Testing of the Health Literacy in Stroke Rehabilitation.

  Hou, W.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Functional Electrical Stimulation Cycling and Central Neuromodulation on Motor Control in Stroke

  Chen, S.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of measurement technology of surface-enhanced Raman spectroscopy for detection of biomolecules

  Liu, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• 支援在地老化之智慧生活實驗室規畫(3/3)

  Tsai, D.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• RNA-Seq Analysis of Transcriptome in Toxocara canis L3-Infected Host

  Liao, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the Therapeutic Effects and Novel Molecular Mechanisms of Resveratrol in Human Osteosarcoma: the Treatment of Metastatic Cancer

  Chien, M.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Reflex Pelvic Floor Muscle Activities in Women with Urinary Incontinence (II)

  Yang, J.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• 末期腎臟疾病患者的治療方式與慢性疾病之相關性研究

  Wang, Y.

  5/1/13 → 7/31/14

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• Antibody-Mediated Immune Suppression of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)

  Burnouf, T. P. R.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討小泛素蛋白酶Sentrin-specific protease 2 參與轉型生長因子-beta訊息傳遞的作用機制(1/2)

  Chang, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• 運用凝血?作為基楚之癒合組織工程：與韌帶及肌腱組織癒合為例

  Hsieh, M.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology