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• Prostate Cancer Malignancy Is Enhanced by Glycotoxins

  Wu, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Kidney Injury and Heat Shock Protein Modulate the Atrial Electrophysiological Characterisitcs

  Hsieh, M.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• New Strategies of Parkinson’s Disease Treatment

  Chiang, Y.

  8/1/14 → 12/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role of Synovium in Osteoarthritis Progress and Cartilage Regeneration

  Yang, K.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role of Oxidative Stress-triggered Redox Adaptation Mechanism and Genetically Endowed Expression Profile of Antioxidant Enzymes in the modulation of Intrinsic and Acquired Chemoand Radio-resistance of Human Hepatocellular Carcinoma Cells

  Chiou, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Functional Role of Transcription Factor Sp1 in Brain Neuronal Injury (III)

  Chang, W.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Can Sesamin Alone or Cotheapy with Anti-DM Medicines Alleviate the Abnormal Intermediate Metabolites of Glucose and Fatty Acids, the Oxygen Consumption and Renal Fibrotic Progression?

  Peng, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the Function and Regulation of miRNAs in Pancreatic Cancer Progression (I)

  Huang, M.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Application of Clinical Anti-Arthralgia Formulas of Traditional Chinese Medicine to Arthritis

  Wang, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌是目前世界上女性癌症病患中為數最多的癌症之ㄧ。腺病毒蛋白type 5 E1A (E1A)和許多抗腫瘤作用有關，曾於多種癌症如乳癌、卵巢癌及頭頸癌之病患進行臨床基因治療試驗。許多的研究指出E1A具有多項抗腫瘤的功能，包括抑制腫瘤的發生、增加腫瘤細胞對於化療藥物的感受性以及減少腫瘤轉移的現象。腫瘤的轉移對於癌症患者的死亡率有極大的影響當然也包括了乳癌的患者。E1A於抑制腫瘤發展的過程中具有多重生物學上的意義，這也促使我們想要釐清E1A抑制癌症的機制。因此，我們對於了解E1A抑制癌症轉移相關的分子機制感到有興趣，並期望藉以作為未來改進乳癌病人臨床試驗的基石。我們初步的實驗結果顯示，E1A可以有效的抑制Glucose-regulated protein 78 (GRP78)這種已被廣泛報導和腫瘤惡化及轉移相關的蛋白的表現。 提出此研究計劃之目的在於詳細探討E1A所造成的抑制癌轉移作用中，GRP78所扮演的生物功能及其調控的機轉。為了達到此目的，我們將著重於E1A如何調控GRP78表現並進而展現對乳癌轉移的抑制作用。以下為此項研究計畫的四大主要目標： 目標一：探討GRP78在E1A所抑制之癌細胞移行及侵入作用中所扮演的角色 目標二：研究E1A抑制GRP78表現之分子機轉 目標三：於動物模式中驗證GRP78的表現對於E1A抗腫瘤作用的影響 目標四：探討GRP78及其相關分子的表現在乳癌病人的臨床重要性 完成以上的主要目標能夠幫助我們對於E1A之抗腫瘤轉移作用建立更加詳細的分子訊息傳遞機制。另外，藉由此研究計畫的新發現也許可以對未來發展癌症治療上提供更多具有潛力的標的物。

  Wang, W.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Effects of the APOE4 Allele on Cerebral Structural and Functional Connectivity---A Diffusion Tensor Imaging and Resting-State MRI Study

  Chen, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Different Oils Combined with Lycium Barbarum Extract on Chemical-Induced Liver Inflammation and Fibrosis in Rats

  Chao, J. C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Evaluation on Cervical Cancer Prevention and Treatment Policy in Taiwan

  Tang, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Radioopacifier in Mineral Trioxide Aggregate-Synthesis and Solidification of Bi2o3/Zro2 Composite Powders

  Lin, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Chitosan Nanoparticle as a Macrophage-Targeting Drug Delivery Carrier

  Mi, F.

  8/1/14 → 8/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Pre-Clinical and Clinical Study for Multi-Nation Intelligent Medication Safety System

  Li, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討不同選擇作用之組織蛋白去乙醯?調節成分抑制神經發炎之機制及其對腦內出血與腦炎之治療特性評估(2/3)

  Hsiao, G.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular and Cellular Mechanism of Adipocyte Modulatory Effects on Pulmonary Vein and Atrium

  Chen, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Identification of Human Viral Micrornas and Its Targets by Using Small RNA Sequencing Data Based on RNA Sequence and Structure Features

  Chang, T.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Building a Cancer Progress Model Based on PPI Network and Gene Expression Changes and Its Applications for Classification of Cancer Subtypes

  Chiu, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of CCR5/RANTES in Neurodegeneration

  Chou, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• 國人口腔健康監測調查企劃案

  Tsai, H.

  8/4/14 → 12/31/14

  Project: A - Government Institution › c - Ministry of Health and Welfare

• Application of resilience engineering in emergent health care services

  蘇, 清., Chuang, S., 馬, 漢. & 蔡, 哲.

  8/7/14 → 8/6/15

  Project: A - Government Institution › a - National Health Research Institutes

• Valproate治療腦外傷病人的臨床研究

  Chang, C., Chiang, Y., Liao, K., Yang, S., Wu, C. & Chen, K.

  8/7/14 → 8/6/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

• Novel Strategies to Target Long-Lived Plasma Cells for Treating Hemophilia a Inhibitors

  Liu, C.

  9/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Phase I, First-In-Human, Dose-Seeking Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of Orally Administered MPT0E028 in Subjects with Advanced Solid Malignancies without Standard Treatment (I)

  Liou, J.

  9/1/14 → 9/30/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• 北區高階生醫產業聚落及產業規劃-台灣遠距健康產業聚落發展先導計畫

  Yen, Y. & Chen, R.

  9/1/14 → 8/31/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

• Development of 3d-Printing Dynamic Orthosis-For Hemiplegic Lower Limbs( I )

  Chen, S.

  9/1/14 → 11/30/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• 103年度「含中藥材創意商品開發」

  Hou, W.

  9/1/14 → 4/30/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

• Long-term follow-up study of health behaviors among adolescent cohort.

  Chiou, H., Chen, P., Chen, Y., Chang, H., Yang, S. & Chen, Y. C.

  9/1/14 → 12/31/14

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 103年度「103-104年國民長期照護需要調查訪視控管作業」

  Huang, Y.

  9/11/14 → 6/30/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 103年度國民體適能檢測站設置實施計畫

  Kan, N.

  9/24/14 → 3/30/15

  Project: A - Government Institution › d - Ministry of Education

• Study the Interactive Functions of Decoy Receptor 3 and Galectin-3 in Keratinocytes and Macrophages

  Lin, W.

  10/1/14 → 9/30/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Micro-Scale Surface-Enhanced Raman Spectroscopy in Real-Time Single Living Cell Diagnostics (II)

  Peng, P.

  10/1/14 → 9/30/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• TMU103-AE1-B03

  Lin, C.

  10/1/14 → 9/30/15

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• Differential Machinery of Pluripotency Regulation in Stem Cells in Embryonic Stage and Somatic Cancers and Its Clinical Implications in Human Diseases---Crosstalk among Niche Growth Factor/Cytokine Signaling, Extracellular Matrix, and Epigenetic Netw (I)

  Huang, Y.

  10/1/14 → 9/30/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• 專業融入之服務學習模組教材開發—口述歷史加值服務學習教學模組

  Chiu, C. & Liu, M. F.

  10/6/14 → 4/5/15

  Project: A - Government Institution › d - Ministry of Education

• 應用全民健保資料庫探討與追蹤臺灣人體生物資料庫個案健康狀況之研究

  Chung, M.

  10/23/14 → 12/31/17

  Project: A - Government Institution › f - Other (Funded by Government)

• TMU103-AE1-B07

  Ru, H.

  11/1/14 → 10/31/16

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• TMU103-AE1-B08

  Wu, C.

  11/1/14 → 10/31/15

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• The Development and Clinical Application of a Miniature Transcranial Direct Current Stimulator in Rehabilitation Therapy (II)

  Peng, C.

  11/1/14 → 6/30/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• TMU103-AE1-B09

  Lai, M.

  11/1/14 → 10/31/16

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• TMU103-AE1-B11

  Chiu, H.

  11/1/14 → 10/31/15

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 臺北醫學大學自有貴重儀器共用服務計畫

  Lin, C.

  11/1/14 → 12/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• TMU103-AE1-B04

  Chou, C.

  11/1/14 → 10/31/17

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• TMU103-AE1-B10

  Chi, C.

  11/1/14 → 4/30/16

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 設計與合成新穎苯甲醯胺與醯基羥胺取代之雜環化合物分別抑制微小管與組織蛋白去乙醯酉每6為抗癌藥物

  Lai, M.

  11/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• 失智者用路安全保障之研究

  Pai, C.

  11/1/14 → 1/31/15

  Project: A - Government Institution › f - Other (Funded by Government)

• 老年性聽力損失: Cisd2缺失會加速老化過程中的聽力損傷

  Chen, Y.

  11/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• TMU103-AE1-B06

  Lai, H.

  11/1/14 → 12/31/15

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty