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Research Output

2020

Two new, near-infrared, fluorescent probes as potential tools for imaging bone repair

Lin, C. C., Chang, W. H. S., Cheng, T. M., Chiu, L. H., Wang, Y. H., Lin, C. A. J., Ho, Y. S., Zuo, C. S., Wang, Y. M. & Lai, W. F. T., Dec 1 2020, In : Scientific Reports. 10, 1, 2580.

Research output: Contribution to journalArticle

Open Access
2019

A new histone deacetylase inhibitor enhances radiation sensitivity through the induction of misfolded protein aggregation and autophagy in triple-negative breast cancer

Chiu, H. W., Yeh, Y. L., Ho, S. Y., Wu, Y. H., Wang, B. J., Huang, W. J., Ho, Y. S., Wang, Y. J., Chen, L. C. & Tu, S. H., Nov 1 2019, In : Cancers. 11, 11, 1703.

Research output: Contribution to journalArticle

Open Access

DNA primase polypeptide 1 (PRIM1) involves in estrogen-induced breast cancer formation through activation of the G2/M cell cycle checkpoint

Lee, W-H., Chen, L-C., Lee, C-J., Huang, C-C., Ho, Y-S., Yang, P-S., Ho, C-T., Chang, H-L., Lin, I-H., Chang, H-W., Liu, Y-R., Wu, C-H. & Tu, S-H., Feb 1 2019, In : International Journal of Cancer. 144, 3, p. 615-630 16 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Melatonin promotes neuroblastoma cell differentiation by activating hyaluronan synthase 3-induced mitophagy

Lee, W. J., Chen, L. C., Lin, J. H., Cheng, T. C., Kuo, C. C., Wu, C. H., Chang, H. W., Tu, S. H. & Ho, Y. S., Jan 1 2019, In : Cancer Medicine. 8, 10, p. 4821-4835 15 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Membrane protein-regulated networks across human cancers

Lin, C. Y., Lee, C. H., Chuang, Y. H., Lee, J. Y., Chiu, Y. Y., Wu Lee, Y. H., Jong, Y. J., Hwang, J. K., Huang, S. H., Chen, L. C., Wu, C. H., Tu, S. H., Ho, Y. S. & Yang, J. M., Dec 1 2019, In : Nature Communications. 10, 1, 3131.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Proteasome 26s subunit, non-atpase 3 (Psmd3) regulates breast cancer by stabilizing her2 from degradation

Fararjeh, A. S., Chen, L. C., Ho, Y. S., Cheng, T. C., Liu, Y. R., Chang, H. L., Chang, H. W., Wu, C. H. & Tu, S. H., Apr 1 2019, In : Cancers. 11, 4, 527.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Small G protein signalling modulator 2 (SGSM2) is involved in oestrogen receptor-positive breast cancer metastasis through enhancement of migratory cell adhesion via interaction with E-cadherin

Lin, J. H., Lee, W. J., Wu, H. C., Wu, C. H., Chen, L. C., Huang, C. C., Chang, H. L., Cheng, T. C., Chang, H. W., Ho, C. T., Tu, S. H. & Ho, Y. S., Jan 1 2019, In : Cell Adhesion and Migration.

Research output: Contribution to journalArticle

2 Citations (Scopus)
Open Access

The α9 nicotinic acetylcholine receptor mediates nicotine-induced pd-l1 expression and regulates melanoma cell proliferation and migration

Nguyen, H. D., Liao, Y. C., Ho, Y. S., Chen, L. C., Chang, H. W., Cheng, T. C., Liu, D., Lee, W. R., Shen, S. C., Wu, C. H. & Tu, S. H., Dec 2019, In : Cancers. 11, 12, 1991.

Research output: Contribution to journalArticle

Open Access

Triple-negative breast cancer: Current understanding and future therapeutic breakthrough targeting cancer stemness

Lee, K. L., Kuo, Y. C., Ho, Y. S. & Huang, Y. H., Sep 2019, In : Cancers. 11, 9, 1334.

Research output: Contribution to journalReview article

Open Access
19 Citations (Scopus)
2018

Anticancer effect of curcumin on breast cancer and stem cells

Liu, H-T. & Ho, Y-S., Jun 2018, In : Food Science and Human Wellness. p. 134-137

Research output: Contribution to journalReview article

8 Citations (Scopus)
12 Citations (Scopus)
14 Citations (Scopus)
3 Citations (Scopus)

Nutraceutical support for respiratory diseases

Hwang, Y. Y. & Ho, Y-S., Sep 2018, In : Food Science and Human Wellness. p. 205-208

Research output: Contribution to journalReview article

Oestrogen receptor-regulated glutathione S-transferase mu 3 expression attenuates hydrogen peroxide-induced cytotoxicity, which confers tamoxifen resistance on breast cancer cells

Lin, J. H., Tu, S. H., Chen, L. C., Huang, C. C., Chang, H. L., Cheng, T. C., Chang, H. W., Wu, C. H., Wu, H. C. & Ho, Y. S., Jan 1 2018, (Accepted/In press) In : Breast Cancer Research and Treatment.

Research output: Contribution to journalArticle

1 Citation (Scopus)
24 Citations (Scopus)

The impact of the effectiveness of GATA3 as a prognostic factor in breast cancer

Fararjeh, A-FS., Tu, S-H., Chen, L-C., Liu, Y-R., Lin, Y-K., Chang, H-L., Chang, H-W., Wu, C-H., Hwang-Verslues, W. W. & Ho, Y-S., 2018, In : Human Pathology. 80, p. 219-230 12 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

α-Tocopherol succinate enhances pterostilbene anti-tumor activity in human breast cancer cells in vivo and in vitro

Tam, K. W., Ho, C. T., Tu, S. H., Lee, W. J., Huang, C. S., Chen, C. S., Wu, C. H., Lee, C. H. & Ho, Y. S., Jan 1 2018, In : Oncotarget. 9, 4, p. 4593-4606 14 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2017

An apple a day to prevent cancer formation: Reducing cancer risk with flavonoids

Tu, S-H., Chen, L-C. & Ho, Y-S., Jan 1 2017, In : Journal of Food and Drug Analysis. 25, 1, p. 119-124 6 p.

Research output: Contribution to journalReview article

24 Citations (Scopus)
5 Citations (Scopus)

P53-dependent downregulation of hTERT protein expression and telomerase activity induces senescence in lung cancer cells as a result of pterostilbene treatment

Chen, R. J., Wu, P. H., Ho, C. T., Way, T. D., Pan, M. H., Chen, H. M., Ho, Y. S. & Wang, Y. J., Aug 10 2017, In : Cell death & disease. 8, 8, p. e2985

Research output: Contribution to journalArticle

20 Citations (Scopus)
2016

Alterations in histone deacetylase 8 lead to cell migration and poor prognosis in breast cancer

Hsieh, C. L., Ma, H. P., Su, C-M., Chang, Y. J., Hung, W. Y., Ho, Y. S., Huang, W. J. & Lin, R. K., Apr 15 2016, In : Life Sciences. 151, p. 7-14 8 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Protein phosphatase Mg2+/Mn2+ dependent 1F promotes smoking-induced breast cancer by inactivating phosphorylatedp53- induced signals

Tu, S-H., Lin, Y. C., Huang, C-C., Yang, P. S., Chang, H. W., Chang, C. H., Wu, C-H., Chen, L-C. & Ho, Y-S., 2016, In : Oncotarget. 7, 47, p. 77516-77531 16 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Pu-erh tea attenuates smoking-induced foam cell formation through inhibition of the α9-nicotinic-acetylcholine receptor expression in monocytes: An ex vivo study

Chen, L. C., Chen, M. Y., Tu, S. H., Pan, M. H., Lo, C. Y., Ho, C. T., Wu, C. H. & Ho, Y. S., Apr 1 2016, In : Journal of Functional Foods. 22, p. 132-144 13 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Pu-erh Tea Extract Attenuates Nicotine-Induced Foam Cell Formation in Primary Cultured Monocytes: An in Vitro Mechanistic Study

Tu, S. H., Chen, M. Y., Chen, L. C., Mao, Y. T., Ho, C. H., Lee, W. J., Lin, Y-K., Pan, M. H., Lo, C. Y., Chen, C. L., Yen, Y., Whang-Peng, J., Ho, C. T., Wu, C. H. & Ho, Y. S., Apr 27 2016, In : Journal of Agricultural and Food Chemistry. 64, 16, p. 3186-3195 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

The kinome pathways in radioresistance breast cancer stem cells

Fararjeh, A. F. & Ho, Y. S., 2016, In : Journal of Thoracic Disease. 8, 11, p. E1470-E1472

Research output: Contribution to journalComment/debate

Thermosenstive injectable hydrogel for drug delivery

Jhan, H. J., Ho, H-O., Sheu, M-T., Shen, S-C., Ho, Y-S. & Liu, J-J., Jun 14 2016, Patent No. US 9,364,545 B2 , Jun 19 2014, Priority date Jun 19 2014

Research output: Patent

4 Downloads (Pure)
2015

Down-regulation of α-L-fucosidase 1 expression confers inferior survival for triple-negative breast cancer patients by modulating the glycosylation status of the tumor cell surface

Cheng, T. C., Tu, S. H., Chen, L. C., Chen, M. Y., Chen, W. Y., Lin, Y-K., Ho, C. T., Lin, S. Y., Wu, C. H. & Ho, Y. S., 2015, In : Oncotarget. 6, 25, p. 21283-21300 18 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
20 Citations (Scopus)

Novel Link of Anti-apoptotic ATF3 with Pro-apoptotic CTMP in the Ischemic Brain

Huang, C. Y., Chen, J. J., Wu, J. S., Tsai, H. D., Lin, H., Yan, Y. T., Hsu, C-Y., Ho, Y-S. & Lin, T. N., 2015, In : Molecular Neurobiology. 51, 2, p. 543-557 15 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Skp2-Mediated RagA Ubiquitination Elicits a Negative Feedback to Prevent Amino-Acid-Dependent mTORC1 Hyperactivation by Recruiting GATOR1

Jin, G., Lee, S. W., Zhang, X., Cai, Z., Gao, Y., Chou, P. C., Rezaeian, A. H., Han, F., Wang, C. Y., Yao, J. C., Gong, Z., Chan, C. H., Huang, C. Y., Tsai, F. J., Tsai, C. H., Tu, S. H., Wu, C. H., Sarbassov, D. D., Ho, Y. S. & Lin, H. K., Jun 18 2015, In : Molecular Cell. 58, 6, p. 989-1000 12 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)
2014

Antroquinonol D, isolated from Antrodia camphorata, with DNA demethylation and anticancer potential

Wang, S. C., Li, Z-H., Hsu, C. H., Chang, Y. J., Chang, M. S., Wang, Y. C., Ho, Y. S., Wen, W. C. & Lin, R. K., Jun 18 2014, In : Journal of Agricultural and Food Chemistry. 62, 24, p. 5625-5635 11 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

CHRNA9 polymorphisms and smoking exposure synergize to increase the risk of breast cancer in Taiwan

Hsieh, Y. C., Lee, C. H., Tu, S. H., Wu, C. H., Hung, C. S., Hsieh, M. C., Chuang, C. W., Ho, Y. S. & Chiou, H. Y., Nov 1 2014, In : Carcinogenesis. 35, 11, p. 2520-2525 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

High-level expression of CXCR4 in breast cancer is associated with early distant and bone metastases

Hung, C-S., Su, H. Y., Liang, H-H., Lai, C. W., Chang, Y-C., Ho, Y-S., Wu, C-H., Ho, J-D., Wei, P-L. & Chang, Y-J., 2014, In : Tumor Biology. 35, 2, p. 1581-1588 8 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Novel peptides suppress VEGFR-3 activity and antagonize VEGFR-3-mediated oncogenic effects

Chang, Y. W., Su, C. M., Su, Y-H., Ho, Y. S., Lai, H. H., Chen, H. A., Kuo, M. L., Hung, W. C., Chen, Y. W., Wu, C. H., Chen, P. S. & Su, J. L., 2014, In : Oncotarget. 5, 11, p. 3823-3835 13 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Potent anti-cancer effect of 39-hydroxypterostilbene in human colon xenograft tumors

Cheng, T. C., Lai, C. S., Chung, M. C., Kalyanam, N., Majeed, M., Ho, C. T., Ho, Y. S. & Pan, M. H., Nov 12 2014, In : PLoS One. 9, 11, e111814.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Protective effect of non-ionizing radiation from ceramic far infrared (cFIR)-emitting material against oxidative stress on human breast epithelial cells

Leung, T-K., Lee, C-M., Lin, S. L., Wu, C. H., Chiou, J. F., Huang, P. J., Shen, L. K., Hung, C. S., Ho, Y. S., Wang, H. J., Kung, C. H., Lin, Y. H. & Yeh, H. M., 2014, In : Journal of Medical and Biological Engineering. 34, 1, p. 69-75 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

The regulation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumor promotion by estradiol in female A/J mice

Chen, R. J., Chang, C. Y., Chang, L. W., Siao, S. H., Ho, Y. S., Wu, C. H., Foo, N. P., Lin, P. & Wang, Y. J., Mar 28 2014, In : PLoS One. 9, 3, e93152.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Vascular Endothelial Growth Factor-C Upregulates Cortactin and Promotes Metastasis of Esophageal Squamous Cell Carcinoma

Su, C-M., Su, Y-H., Chiu, C. F., Chang, Y. W., Hong, C. C., Yu, Y. H., Ho, Y. S., Wu, C. H., Yen, C. S. & Su, J. L., 2014, In : Annals of Surgical Oncology. 21, 4, p. 767-775 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2013

Alteration of α-tocopherol-associated protein (TAP) expression in human breast epithelial cells during breast cancer development

Tam, K-W., Ho, C. T., Lee, W. J., Tu, S-H., Huang, C. S., Chen, C. S., Lee, C-H., Wu, C-H. & Ho, Y-S., Jun 1 2013, In : Food Chemistry. 138, 2-3, p. 1015-1021 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Areca nut-induced buccal mucosa fibroblast contraction and its signaling: A potential role in oral submucous fibrosis-a precancer condition

Chang, M. C., Lin, L. D., Wu, H. L., Ho, Y. S., Hsien, H. C., Wang, T. M., Jeng, P. Y., Cheng, R. H., Hahn, L. J. & Jeng, J. H., May 2013, In : Carcinogenesis. 34, 5, p. 1096-1104 9 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Hexahydro-β-acids potently inhibit 12- O -tetradecanoylphorbol 13-acetate-induced skin inflammation and tumor promotion in mice

Hsu, C-H., Ho, Y-S., Lai, C. S., Hsieh, S. C., Chen, L. H., Lin, E., Ho, C. T. & Pan, M. H., Nov 27 2013, In : Journal of Agricultural and Food Chemistry. 61, 47, p. 11541-11549 9 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Long-term ethanol exposure-induced hepatocellular carcinoma cell migration and invasion through lysyl oxidase activation are attenuated by combined treatment with pterostilbene and curcumin analogues

Huang, C. S., Ho, C. T., Tu, S. H., Pan, M. H., Chuang, C. H., Chang, H. W., Chang, C. H., Wu, C. H. & Ho, Y. S., May 8 2013, In : Journal of Agricultural and Food Chemistry. 61, 18, p. 4326-4335 10 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Luteolin sensitises drug-resistant human breast cancer cells to tamoxifen via the inhibition of cyclin E2 expression

Tu, S. H., Ho, C. T., Liu, M. F., Huang, C. S., Chang, H. W., Chang, C. H., Wu, C. H. & Ho, Y. S., 2013, In : Food Chemistry. 141, 2, p. 1553-1561 9 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
39 Citations (Scopus)

Shikonin suppresses the migratory ability of hepatocellular carcinoma cells

Wei, P. L., Tu, C. C., Chen, C. H., Ho, Y. S., Wu, C. T., Su, H. Y., Chen, W. Y., Liu, J. J. & Chang, Y. J., Aug 28 2013, In : Journal of Agricultural and Food Chemistry. 61, 34, p. 8191-8197 7 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Tea extracts confer its antiproliferating effects through inhibition of nicotine- and estrogen-induced 9-nicotinic acetylcholine receptor upregulation in human breast cancer cells

Ho, Y. S. & Pan, M. H., 2013, Nutrition, Functional and Sensory Properties of Foods. Royal Society of Chemistry, p. 256-268 13 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

The molecular targets of garcinol confer antitumor effects

Ho, C. T., Pan, M. H. & Ho, Y. S., 2013, Nutrition, Functional and Sensory Properties of Foods. Royal Society of Chemistry, p. 251-255 5 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution