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Yuan-Feng Lin

Associate Professor

 https://orcid.org/0000-0003-4456-0766
  • 337 Citations
  • 13 h-Index
20012019
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Personal profile

Education

  • 2007 Ph.D. (Philosophy), Graduate Institute of Pharmacognosy, Taipei Medical University
  • 1999 M.S., School of Pharmacy, Taipei Medical University 

Awards

  • 2015 Visiting Scholars, Genomics Research Center, Academia Sinica, Taiwan
  • 2015 Reviewer for PLoS one
  • 2008, 2009 and 2013 Reviewer for Journal of Cellular Biochemistry

Experience

  • Associate Professor, Graduate Institute of Clinical Medicine, Taipei Medical University
  • 2014, Assistant Professor, Graduate Institute of Clinical Medicine, Taipei Medical University

Research Interests

  • Cancer Drug Discovery
  • Protein-Protein Interaction

URL

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Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2015 2019

鑑定Gαh-連結型的接受器及探討其於三陰性乳癌之轉譯醫學應用

Lin, Y.

8/1/18 → 7/31/19

Project: A - Government Institution › b - Ministry of Science and Technology

探討阻斷Galpha-h與PLC-delta1蛋白質交互作用對抗三陰性乳癌的抗藥性及轉移之機制和轉譯醫學應用(3/3)

Lin, Y.

8/1/17 → 7/31/18

Project: A - Government Institution › b - Ministry of Science and Technology

Studying on the Mechanism and Translational Application of Blocking the Protein-Protein Interaction between Galpha-h and PLC-delta1 in Combating Drug-Resistance and Metastasis of Triple-Negative Breast Cancer

Lin, Y.

8/1/16 → 7/31/17

Project: A - Government Institution › b - Ministry of Science and Technology

Study of the Molecular Mechanism Underlying Psat1-Induced Cancer Metastasis

Lin, Y.

1/1/16 → 7/31/16

Project: A - Government Institution › b - Ministry of Science and Technology

Studying on the Mechanism and Translational Application of Blocking the Protein-Protein Interaction between Galpha-h and PLC-delta1 in Combating Drug-Resistance and Metastasis of Triple-Negative Breast Cancer

Lin, Y.

8/1/15 → 7/31/16

Project: A - Government Institution › b - Ministry of Science and Technology

Research Output 2001 2019

  • 337 Citations
  • 13 h-Index
  • 36 Article

Adenylate kinase 4 modulates oxidative stress and stabilizes HIF-1α to drive lung adenocarcinoma metastasis

Jan, Y. H., Lai, T. C., Yang, C. J., Lin, Y. F., Huang, M. S. & Hsiao, M., Jan 29 2019, In : Journal of Hematology and Oncology. 12, 1, 12.

Research output: Contribution to journal › Article

Adenylate Kinase
Oxidative Stress
Neoplasm Metastasis
Lung Neoplasms
Epithelial-Mesenchymal Transition

FBXL7 Upregulation Predicts a Poor Prognosis and Associates with a Possible Mechanism for Paclitaxel Resistance in Ovarian Cancer

Chiu, H-W., Chang, J-S., Lin, H-Y., Lee, H-H., Kuei, C-H., Lin, C-H., Huang, H-M. & Lin, Y-F., Oct 6 2018, In : Journal of Clinical Medicine. 7, 10

Research output: Contribution to journal › Article

Paclitaxel
Ovarian Neoplasms
Up-Regulation
Inhibitory Concentration 50
Biomarkers
2 Citations (Scopus)

High-level expression of ARID1A predicts a favourable outcome in triple-negative breast cancer patients receiving paclitaxel-based chemotherapy

Lin, Y. F., Tseng, I. J., Kuo, C. J., Lin, H. Y., Chiu, I. J. & Chiu, H. W., Apr 1 2018, In : Journal of Cellular and Molecular Medicine. 22, 4, p. 2458-2468 11 p.

Research output: Contribution to journal › Article

Triple Negative Breast Neoplasms
Paclitaxel
Drug Therapy
Kaplan-Meier Estimate
Inhibitory Concentration 50
1 Citation (Scopus)

MPT0B169 and MPT0B002, New Tubulin Inhibitors, Induce Growth Inhibition, G2/M Cell Cycle Arrest, and Apoptosis in Human Colorectal Cancer Cells

Lee, C. H., Lin, Y. F., Chen, Y. C., Wong, S. M., Juan, S. H. & Huang, H. M., Jan 1 2018, (Accepted/In press) In : Pharmacology. p. 262-271 10 p.

Research output: Contribution to journal › Article

Tubulin Modulators
G2 Phase Cell Cycle Checkpoints
Colorectal Neoplasms
Apoptosis
Growth

OTUD7B upregulation predicts a poor response to paclitaxel in patients with triple-negative breast cancer

Chiu, H. W., Lin, H. Y., Tseng, I. J. & Lin, Y. F., Jan 1 2018, In : Oncotarget. 9, 1, p. 553-565 13 p.

Research output: Contribution to journal › Article

Triple Negative Breast Neoplasms
Paclitaxel
Up-Regulation
Down-Regulation
Breast Neoplasms