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Personal profile


  • 2000, Ph.D., Biochemistry, University of Cambridge, (Pembroke College), U.K.
  • 1991, MSc., Biology, Tunghai University, Taiwan
  • 1987, BA, Literature and Foreign Languages, Tunghai University, Taiwan


  • 2009 Associate Professor, Graduate Institute of Biomedical Informatics, Taipei Medical University
  • 2003 Assistant Professor, Graduate Institute of Biomedical Informatics, Taipei Medical University
  • 2000 Postdoctoral Fellow, National Health Research Institute


  • 2015 Best University Tutor in Taipei Medical University
  • 2015 Award, NIH/NINDS Summer Internship Program Research Poster Competition
  • 2015 Award, MoE Internship Abroad
  • 2015-2017 MOST Award, Multivariate bioinformatics analysis of Taiwanese cancer RNA-seq.
  • 2014 MOST Award, Association between human endogenous retrovirus and cancers using RNA-seq data
  • 2011 MOST Award, A Revolutionary Approach for Disease-associated Pathways Identification: From Genome-wide Network Construction, Pathway Discovery, to Pathway-based Analysis and Validation
  • 2000 MOHW Translation Research Award, Translational research: from systems biology to drug target for cancer metastasis.

Research Interests

  • Bioinformatics
  • Next Generation Sequence data analysis
  • Gene Expression Microarray data analysis
  • Human Endogenous Retroviruses
  • Cancer Genome Biology


Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Lung Neoplasms Medicine & Life Sciences
Proteins Medicine & Life Sciences
Hepatocellular Carcinoma Medicine & Life Sciences
Genes Medicine & Life Sciences
Carcinogenesis Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
Databases Medicine & Life Sciences

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Projects 2010 2018

Research Output 2001 2019

  • 914 Citations
  • 15 h-Index
  • 29 Article
  • 1 Conference contribution
Cyclic AMP-Dependent Protein Kinases
AMP-Activated Protein Kinases
1 Citations

RBM4-SRSF3-MAP4K4 splicing cascade modulates the metastatic signature of colorectal cancer cell

Lin, J. C., Lee, Y. C., Tan, T. H., Liang, Y. C., Chuang, H. C., Fann, Y. C., Johnson, K. R. & Lin, Y. J., Feb 1 2018, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1865, 2, p. 259-272 14 p.

Research output: Contribution to journalArticle

RNA-Binding Proteins
Colorectal Neoplasms
Mitogen-Activated Protein Kinase 8
Alternative Splicing
5 Citations
Aryl Hydrocarbon Receptors
Nitric Oxide Synthase Type III
Blood pressure
1 Citations

The impact of the RBM4-initiated splicing cascade on modulating the carcinogenic signature of colorectal cancer cells

Lin, J. C., Lee, Y. C., Liang, Y. C., Fann, Y. C., Johnson, K. R. & Lin, Y. J., Mar 9 2017, In : Scientific Reports. 7, 44204.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Alternative Splicing
RNA Sequence Analysis
12 Citations