Projects per year
Personal profile
Education
- 2000 Ph.D., Biochemistry, University of Cambridge, (Pembroke College), U.K.
- 1991 MSc., Biology, Tunghai University, Taiwan
- 1987 BA, Literature and Foreign Languages, Tunghai University, Taiwan
Experience
- 2009- Associate Professor, Graduate Institute of Biomedical Informatics, Taipei Medical University
- 2003-2009 Assistant Professor, Graduate Institute of Biomedical Informatics, Taipei Medical University
- 2000-2003 Postdoctoral Fellow, National Health Research Institute
Awards
- 2015 Best University Tutor in Taipei Medical University
- 2015 Award, NIH/NINDS Summer Internship Program Research Poster Competition
- 2015 Award, MoE Internship Abroad
- 2015-2017 MOST Award, Multivariate bioinformatics analysis of Taiwanese cancer RNA-seq.
- 2014 MOST Award, Association between human endogenous retrovirus and cancers using RNA-seq data
- 2011 MOST Award, A Revolutionary Approach for Disease-associated Pathways Identification: From Genome-wide Network Construction, Pathway Discovery, to Pathway-based Analysis and Validation
- 2000 MOHW Translation Research Award, Translational research: from systems biology to drug target for cancer metastasis.
Research Interests
- Bioinformatics
- Next Generation Sequence data analysis
- Gene Expression Microarray data analysis
- Human Endogenous Retroviruses
- Cancer Genome Biology
URL
Fingerprint Dive into the research topics where Yuan-Chii Gladys Lee is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
Lung Neoplasms
Medicine & Life Sciences
Proteins
Medicine & Life Sciences
Hepatocellular Carcinoma
Medicine & Life Sciences
Genes
Medicine & Life Sciences
Methylcholanthrene
Medicine & Life Sciences
Protein Kinases
Medicine & Life Sciences
Databases
Medicine & Life Sciences
Neoplasms
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2010 2018
- 7 Finished
使用RNA-seq數據研究人類免疫缺乏病毒相關癌症的分子機轉
8/1/17 → 7/31/18
Project: B - Project of TMU › h - Other (Funded by TMU)
以RNA-seq分析來探討HIV提高non-AIDS-defining malignancies罹患率之分子機制
7/1/17 → 2/28/18
Project: A - Government Institution › b - Ministry of Science and Technology
Multivariate Bioinformatics Analysis of Taiwanese Cancer RNA-seq data to Study Human Endogenous Retroviruses as Carcinogens
8/1/16 → 7/31/17
Project: A - Government Institution › b - Ministry of Science and Technology
Multivariate Bioinformatics Analysis of Taiwanese Cancer RNA-Seq Data to Study Human Endogenous Retroviruses as Carcinogens
8/1/15 → 7/31/16
Project: A - Government Institution › b - Ministry of Science and Technology
Association between Human Endogenous Retrovirus and Cancers Using RNA-Seq Data
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
Research Output 2001 2019
- 997 Citations
- 17 h-Index
- 29 Article
Simvastatin reduces the carcinogenic effect of 3-methylcholanthrene in renal epithelial cells through histone deacetylase 1 inhibition and RhoA reactivation
Chang, C. C., Huang, K. H., Hsu, S. P., Lee, Y. C. G., Sue, Y. M. & Juan, S. H., Dec 1 2019, In : Scientific Reports. 9, 1, 4606.Research output: Contribution to journal › Article
Open Access
Histone Deacetylase 1
Methylcholanthrene
Simvastatin
Renal Cell Carcinoma
Epithelial Cells
1
Citation
(Scopus)
Synergistic effects of cAMP–dependent protein kinase A and AMP-activated protein kinase on lipolysis in kinsenoside-treated C3H10T1/2 adipocytes
Lee, Y. C. G., Sue, Y. M., Lee, C. K., Huang, H. M., He, J. J., Wang, Y. S. & Juan, S. H., Mar 1 2019, In : Phytomedicine. 55, p. 255-263 9 p.Research output: Contribution to journal › Article
Lipolysis
Cyclic AMP-Dependent Protein Kinases
Adipocytes
Protein Kinases
Lipase
8
Citations
(Scopus)
RBM4-SRSF3-MAP4K4 splicing cascade modulates the metastatic signature of colorectal cancer cell
Lin, J. C., Lee, Y. C., Tan, T. H., Liang, Y. C., Chuang, H. C., Fann, Y. C., Johnson, K. R. & Lin, Y. J., Feb 1 2018, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1865, 2, p. 259-272 14 p.Research output: Contribution to journal › Article
RNA-Binding Proteins
Colorectal Neoplasms
Mitogen-Activated Protein Kinase 8
Cadherins
Alternative Splicing
7
Citations
(Scopus)
3-Methylcholanthrene/Aryl-Hydrocarbon Receptor-Mediated Hypertension Through eNOS Inactivation
Chang, C-C., Hsu, Y-H., Chou, H-C., Lee, Y-C. G. & Juan, S-H., May 1 2017, In : Journal of Cellular Physiology. 232, 5, p. 1020-1029Research output: Contribution to journal › Article
Aryl Hydrocarbon Receptors
Methylcholanthrene
Nitric Oxide Synthase Type III
Hypertension
Blood pressure
3
Citations
(Scopus)
The impact of the RBM4-initiated splicing cascade on modulating the carcinogenic signature of colorectal cancer cells
Lin, J. C., Lee, Y. C., Liang, Y. C., Fann, Y. C., Johnson, K. R. & Lin, Y. J., Mar 9 2017, In : Scientific Reports. 7, 44204.Research output: Contribution to journal › Article
Colorectal Neoplasms
Introns
Alternative Splicing
RNA
RNA Sequence Analysis