Yu-Wen Cheng — Taipei Medical University

Personal profile

Research Interests

Drugs Development of Antimucositis and Anticancer.
Drugs Development of Retinopathy and Age-Relative Macular Degeneration Diseases.
Toxicity testing for food, drugs and cosmetics.

Education

Ph.D. in Toxicology, National Taiwan University

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Projects 2013 2019

2 Active
12 Finished

探討苯乙醇苷衍生物對於藍光與氧化性物質視黃醛引起視網膜退化之藥理作用機制與視網膜病變之保護療效評估(2/3)

Cheng, Y.

8/1/18 → 7/31/19

Project: b - Ministry of Science and Technology

探討一氧化氮奈米載體釋放系統應用於眼腦血管與神經相關之藥理作用機轉與潛在生物效應-探討一氧化氮奈米載體釋放系統於藍光誘發之視網膜病變及相關的藥理或生物效應(2/3)

Cheng, Y.

8/1/18 → 7/31/19

Project: b - Ministry of Science and Technology

探討一氧化氮奈米載體釋放系統應用於眼腦血管與神經相關之藥理作用機轉與潛在生物效應-探討一氧化氮奈米載體釋放系統於藍光誘發之視網膜病變及相關的藥理或生物效應(1/3)

Cheng, Y.

8/1/17 → 7/31/18

Project: b - Ministry of Science and Technology

探討苯乙醇苷衍生物對於藍光與氧化性物質視黃醛引起視網膜退化之藥理作用機制與視網膜病變之保護療效評估(1/3)

Cheng, Y.

8/1/17 → 7/31/18

Project: b - Ministry of Science and Technology

Study on the Mechanism Involved in Nanoparticles-Induced Tight Junction and Aquaporins Damages in Endothelial Cells, as Well as the Effects on Physiological Function of Endothelial Barriers

Li, C. & Cheng, Y.

8/1/15 → 7/31/16

Project: b - Ministry of Science and Technology

Research Output 1996 2019

1211 Citations
20 h-Index
76 Article

The fungus-derived retinoprotectant theissenolactone C improves glaucoma-like injury mediated by MMP-9 inhibition

Lin, F. L., Cheng, Y. W., Yu, M., Ho, J. D., Kuo, Y. C., Chiou, G. C. Y., Chang, H. M., Lee, T. H. & Hsiao, G., Mar 15 2019, In : Phytomedicine. 56, p. 207-214 8 p.

Research output: Contribution to journal › Article

Matrix Metalloproteinase 9

Glaucoma

Reperfusion Injury

Interleukin-1beta

Chemokine CCL2

Novel Protective Effects of Cistanche Tubulosa Extract Against Low-Luminance Blue Light-Induced Degenerative Retinopathy

Wu, M-R., Lin, C-H., Ho, J-D., Hsiao, G. & Cheng, Y-W., 2018, In : Cellular Physiology and Biochemistry. 51, 1, p. 63-79 17 p.

Research output: Contribution to journal › Article

Cistanche

Light

Retinal Pigments

Staining and Labeling

Phototoxic Dermatitis

Safety assessment of the Cistanche tubulosa health food product Memoregain^®: Genotoxicity and 28-day repeated dose toxicity test

Liao, P. L., Li, C. H., Tse, L. S., Kang, J. J. & Cheng, Y. W., Aug 1 2018, In : Food and Chemical Toxicology. 118, p. 581-588 8 p.

Research output: Contribution to journal › Article

Cistanche

Toxicity Tests

Salmonella

health foods

safety assessment

1 Citations

Theissenolactone C exhibited ocular protection of endotoxin-induced uveitis by attenuating ocular inflammatory responses and glial activation

Lin, F. L., Ho, J. D., Cheng, Y. W., Chiou, G. C. Y., Yen, J. L., Chang, H. M., Lee, T. H. & Hsiao, G., Apr 9 2018, In : Frontiers in Pharmacology. 9, APR, 326.

Research output: Contribution to journal › Article

Uveitis

Endotoxins

Neuroglia

Microglia

Tumor Necrosis Factor-alpha

7 Citations

Anti-inflammatory properties of shikonin contribute to improved early-stage diabetic retinopathy

Liao, P. L., Lin, C. H., Li, C. H., Tsai, C. H., Ho, J. D., Chiou, G. C. Y., Kang, J. J. & Cheng, Y. W., Mar 21 2017, In : Scientific Reports. 7, 44985.

Research output: Contribution to journal › Article

Diabetic Retinopathy

Anti-Inflammatory Agents

Retinal Pigments

Inbred C57BL Mouse

Glucose