If you made any changes in Pure these will be visible here soon.

Research Output

  • 2454 Citations
  • 27 h-Index
  • 109 Article
  • 1 Review article
Filter
Article
1999

Engineered recombinant factor VII Q217 variants with altered inhibitor specificities

Chang, Y. J., Hamaguchi, N., Chang, S. C., Ruf, W., Shen, M. C. & Lin, S. W., Aug 24 1999, In : Biochemistry. 38, 34, p. 10940-10948 9 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2001

The distinct roles that Gln-192 and Glu-217 of factor IX play in selectivity for macromolecular substrates and inhibitors

Hsu, Y. C., Hamaguchi, N., Chang, Y. J. & Lin, S. W., Sep 18 2001, In : Biochemistry. 40, 37, p. 11261-11269 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2002
31 Citations (Scopus)
2003

Discontinuous residues of factor IX constitute a surface for binding the anti-factor IX monoclonal antibody A-5

Chang, Y. J., Wu, H. L., Hsu, Y. C., Hamaguchi, N., Shi, G. Y., Shen, M. C. & Lin, S. W., 2003, In : Thrombosis Research. 111, 4-5, p. 293-299 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2004
10 Citations (Scopus)
2005

Evidence of human thrombomodulin domain as a novel angiogenic factor

Shi, C. S., Shi, G. Y., Chang, Y. S., Han, H. S., Kuo, C. H., Liu, C., Huang, H. C., Chang, Y. J., Chen, P. S. & Wu, H. L., Apr 5 2005, In : Circulation. 111, 13, p. 1627-1636 10 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)
2006

Oligozoospermia with normal fertility in male mice lacking the androgen receptor in testis peritubular myoid cells

Zhang, C., Yeh, S., Chen, Y. T., Wu, C. C., Chuang, K. H., Lin, H. Y., Wang, R. S., Chang, Y. J., Mendis-Handagama, C., Hu, L., Lardy, H. & Chang, C., Nov 21 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 47, p. 17718-17723 6 p.

Research output: Contribution to journalArticle

96 Citations (Scopus)
2007

ASC-J9 ameliorates spinal and bulbar muscular atrophy phenotype via degradation of androgen receptor

Yang, Z., Chang, Y. J., Yu, I. C., Yeh, S., Wu, C. C., Miyamoto, H., Merry, D. E., Sobue, G., Chen, L. M., Chang, S. S. & Chang, C., Mar 2007, In : Nature Medicine. 13, 3, p. 348-353 6 p.

Research output: Contribution to journalArticle

120 Citations (Scopus)

Promotion of bladder cancer development and progression by androgen receptor signals

Miyamoto, H., Yang, Z., Chen, Y. T., Ishiguro, H., Uemura, H., Kubota, Y., Nagashima, Y., Chang, Y. J., Hu, Y. C., Tsai, M. Y., Yeh, S., Messing, E. M. & Chang, C., Apr 4 2007, In : Journal of the National Cancer Institute. 99, 7, p. 558-568 11 p.

Research output: Contribution to journalArticle

258 Citations (Scopus)

Suppression of androgen receptor transactivation and prostate cancer cell growth by heterogeneous nuclear ribonucleoprotein A1 via interaction with androgen receptor coregulator ARA54

Yang, Z., Chang, Y. J., Miyamoto, H., Yeh, S., Yao, J. L., Di Sant'Agnese, P. A., Tsai, M. Y. & Chang, C., Mar 2007, In : Endocrinology. 148, 3, p. 1340-1349 10 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Transgelin functions as a suppressor via inhibition of ARA54-enhanced androgen receptor transactivation and prostate cancer cell growth

Yang, Z., Chang, Y. J., Miyamoto, H., Ni, J., Niu, Y., Chen, Z., Chen, Y. L., Yao, J. L., Di Sant'Agnese, P. A. & Chang, C., Feb 2007, In : Molecular Endocrinology. 21, 2, p. 343-358 16 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)
2008

Mutation of human plasminogen kringle 1-5 enhances anti-angiogenic action via increased interaction with integrin αvβ3

Chang, P. C., Chang, Y. J., Wu, H. L., Chang, C. W., Lin, C. I., Wang, W. C. & Shi, G. Y., Apr 2008, In : Thrombosis and Haemostasis. 99, 4, p. 729-738 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Subfertility with defective folliculogenesis in female mice lacking testicular orphan nuclear receptor 4

Chen, L. M., Wang, R. S., Lee, Y. F., Liu, N. C., Chang, Y. J., Wu, C. C., Xie, S., Hung, Y. C. & Chang, C., Apr 2008, In : Molecular Endocrinology. 22, 4, p. 858-867 10 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)
2009
62 Citations (Scopus)
2010

Glucose-Regulated protein 78 (GRP78) silencing enhances cell migration but does not influence cell proliferation in hepatocellular carcinoma

Chang, Y-J., Chiu, C. C., Wu, C-H., An, J., Wu, C. C., Liu, T. Z., Wei, P-L. & Huang, M-T., Jun 2010, In : Annals of Surgical Oncology. 17, 6, p. 1703-1709 7 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Glucose-regulated protein 78 Is a novel contributor to acquisition of resistance to sorafenib in hepatocellular carcinoma

Chiou, J-F., Tai, C-J., Huang, M-T., Wei, P-L., Wang, Y. H., An, J., Wu, C-H., Liu, T. Z. & Chang, Y-J., Feb 2010, In : Annals of Surgical Oncology. 17, 2, p. 603-612 10 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

Knockdown of thrombomodulin enhances HCC cell migration through increase of ZEB1 and decrease of E-cadherin gene expression

Huang, M. T., Wei, P. L., Liu, J. J., Liu, D. Z., Huang, H. C., An, J., Wu, C. C., Wu, C. H., Ho, Y. S., Yang, Y. Y. & Chang, Y. J., Dec 2010, In : Annals of Surgical Oncology. 17, 12, p. 3379-3385 7 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Overexpression and activation of the α9-nicotinic receptor during tumorigenesis in human breast epithelial cells

Lee, C. H., Huang, C. S., Chen, C. S., Tu, S. H., Wang, Y. J., Chang, Y. J., Tam, K. W., Wei, P. L., Cheng, T. C., Chu, J. S., Chen, L. C., Wu, C. H. & Ho, Y. S., Sep 8 2010, In : Journal of the National Cancer Institute. 102, 17, p. 1322-1335 14 p.

Research output: Contribution to journalArticle

105 Citations (Scopus)

Role of DNA methyltransferase 1 in hormone-resistant prostate cancer

Chen, M. F., Chen, W. C., Chang, Y. J., Wu, C. F. & Wu, C. T., Sep 2010, In : Journal of Molecular Medicine. 88, 9, p. 953-962 10 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2011
7 Citations (Scopus)

Crosstalk between nicotine and estrogen-induced estrogen receptor activation induces α9-nicotinic acetylcholine receptor expression in human breast cancer cells

Lee, C. H., Chang, Y. C., Chen, C. S., Tu, S. H., Wang, Y. J., Chen, L. C., Chang, Y. J., Wei, P. L., Chang, H. W., Chang, C. H., Huang, C. S., Wu, C. H. & Ho, Y. S., Sep 2011, In : Breast Cancer Research and Treatment. 129, 2, p. 331-345 15 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)

Enhancement of temozolomide-induced apoptosis by valproic acid in human glioma cell lines through redox regulation

Chen, C. H., Chang, Y. J., Ku, M. S. B., Chung, K. T. & Yang, J. T., Mar 2011, In : Journal of Molecular Medicine. 89, 3, p. 303-315 13 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Glucose-regulated protein 78 (GRP78) mediated the efficacy to curcumin treatment on hepatocellular carcinoma

Chang, Y. J., Tai, C. J., Kuo, L. J., Wei, P. L., Liang, H. H., Liu, T. Z., Wang, W., Tai, C. J., Ho, Y. S., Wu, C. H. & Huang, M. T., Aug 2011, In : Annals of Surgical Oncology. 18, 8, p. 2395-2403 9 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)
30 Citations (Scopus)

Nicotine enhances colon cancer cell migration by induction of fibronectin

Wei, P. L., Kuo, L. J., Huang, M. T., Ting, W. C., Ho, Y. S., Wang, W., An, J. & Chang, Y. J., Jun 2011, In : Annals of Surgical Oncology. 18, 6, p. 1782-1790 9 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Nicotine-induced human breast cancer cell proliferation attenuated by garcinol through down-regulation of the nicotinic receptor and cyclin D3 proteins

Chen, C. S., Lee, C-H., Hsieh, C. D., Ho, C. T., Pan, M. H., Huang, C. S., Tu, S-H., Wang, Y. J., Chen, L-C., Chang, Y-J., Wei, P-L., Yang, Y-Y., Wu, C-H. & Ho, Y-S., Jan 2011, In : Breast Cancer Research and Treatment. 125, 1, p. 73-87 15 p.

Research output: Contribution to journalArticle

83 Citations (Scopus)

Nicotine promotes cell migration through alpha7 nicotinic acetylcholine receptor in gastric cancer cells

Lien, Y. C., Wang, W., Kuo, L. J., Liu, J. J., Wei, P. L., Ho, Y. S., Ting, W. C., Wu, C. H. & Chang, Y. J., Sep 2011, In : Annals of Surgical Oncology. 18, 9, p. 2671-2679 9 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Normoxically overexpressed hypoxia inducible factor 1-alpha is involved in arsenic trioxide resistance acquisition in hepatocellular carcinoma

Tung, J. N., Cheng, Y. W., Hsu, C. H., Liu, T. Z., Hsieh, P. Y., Ting, L. L., Ko, H. L., Chang, Y. J., Chiou, J. F. & Wu, A. T. H., May 2011, In : Annals of Surgical Oncology. 18, 5, p. 1492-1500 9 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Oncological and functional outcomes of intersphincteric resection for low rectal cancer

Kuo, L. J., Hung, C. S., Wu, C. H., Wang, W., Tam, K. W., Liang, H. H., Chang, Y. J. & Wei, P. L., Sep 2011, In : Journal of Surgical Research. 170, 1, p. e93-e98

Research output: Contribution to journalArticle

32 Citations (Scopus)

Tea polyphenol (-)-epigallocatechin-3-gallate inhibits nicotine- and estrogen-induced α9-nicotinic acetylcholine receptor upregulation in human breast cancer cells

Tu, S. H., Ku, C. Y., Ho, C. T., Chen, C. S., Huang, C. S., Lee, C. H., Chen, L. C., Pan, M. H., Chang, H. W., Chang, C. H., Chang, Y. J., Wei, P. L., Wu, C. H. & Ho, Y. S., Mar 2011, In : Molecular Nutrition and Food Research. 55, 3, p. 455-466 12 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)
12 Citations (Scopus)
2012
15 Citations (Scopus)
27 Citations (Scopus)

GroEL1, from chlamydia pneumoniae, induces vascular adhesion molecule 1 expression by p37AUF1 in endothelial cells and hypercholesterolemic rabbit

Huang, C. Y., Shih, C. M., Tsao, N. W., Chen, Y. H., Li, C. Y., Chang, Y. J., Chang, N. C., Ou, K. L., Lin, C. Y., Lin, Y. W., Nien, C. H. & Lin, F. Y., Aug 10 2012, In : PLoS One. 7, 8, e42808.

Research output: Contribution to journalArticle

10 Citations (Scopus)

GRP78 knockdown enhances apoptosis via the down-regulation of oxidative stress and akt pathway after epirubicin treatment in colon cancer DLD-1 cells

Chang, Y. J., Huang, Y. P., Li, Z. L. & Chen, C. H., Apr 18 2012, In : PLoS One. 7, 4, e35123.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Knockdown survivin expression reduces the efficacy of curcumin treatment in hepatocellular carcinoma cells

Hung, C. S., Liu, H. H., Huang, M. T., Cheng, C. W., Kuo, L. J., Ho, Y. S., Wu, C. H., Chen, C. M., Wei, P. L. & Chang, Y. J., Oct 2012, In : Annals of Surgical Oncology. 19, 11, p. 3547-3555 9 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
34 Citations (Scopus)
24 Citations (Scopus)
25 Citations (Scopus)
22 Citations (Scopus)

Survivin-mediated therapeutic efficacy of gemcitabine through glucose-regulated protein 78 in hepatocellular carcinoma

Hung, C. S., Lin, S. F., Liu, H. H., Kuo, L. J., Li, L. T., Su, H. Y., Liew, P. L., Lin, F. Y., Wei, P. L., Liu, D. Z. & Chang, Y. J., Aug 2012, In : Annals of Surgical Oncology. 19, 8, p. 2744-2752 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2013
40 Citations (Scopus)

Ardisianone, a natural benzoquinone, efficiently induces apoptosis in human hormone-refractory prostate cancers through mitochondrial damage stress and survivin downregulation

Yu, C. C., Wu, P. J., Hsu, J. L., Ho, Y. F., Hsu, L. C., Chang, Y. J., Chang, H. S., Chen, I. S. & Guh, J. H., Jan 2013, In : Prostate. 73, 2, p. 133-145 13 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
14 Citations (Scopus)
19 Citations (Scopus)
16 Citations (Scopus)

MicroRNA-200a/b influenced the therapeutic effects of curcumin in hepatocellular carcinoma (HCC) cells

Liang, H. H., Wei, P. L., Hung, C. S., Wu, C. T., Wang, W., Huang, M. T. & Chang, Y. J., 2013, In : Tumor Biology. 34, 5, p. 3209-3218 10 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
39 Citations (Scopus)

New therapeutic approach to suppress castration-resistant prostate cancer using ASC-J9 via targeting androgen receptor in selective prostate cells

Lai, K. P., Huang, C. K., Chang, Y. J., Chung, C. Y., Yamashita, S., Li, L., Lee, S. O., Yeh, S. & Chang, C., Feb 2013, In : American Journal of Pathology. 182, 2, p. 460-473 14 p.

Research output: Contribution to journalArticle

57 Citations (Scopus)