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Research Output 1999 2019

  • 2263 Citations
  • 26 h-Index
  • 108 Article
  • 1 Review article
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Article
2019
2 Citations (Scopus)

Bromelain inhibits the ability of colorectal cancer cells to proliferate via activation of ROS production and autophagy

Chang, T. C., Wei, P. L., Makondi, P. T., Chen, W. T., Huang, C. Y. & Chang, Y. J., Jan 1 2019, In : PLoS One. 14, 1, e0210274.

Research output: Contribution to journalArticle

bromelains
Bromelains
autophagy
Autophagy
colorectal neoplasms
1 Citation (Scopus)
Bioinformatics
Computational Biology
colorectal neoplasms
MicroRNAs
microRNA

Genetic variants in the circadian rhythm pathway as indicators of prostate cancer progression

Yu, C. C., Chen, L. C., Chiou, C. Y., Chang, Y. J., Lin, V. C., Huang, C. Y., Lin, I. L., Chang, T. Y., Lu, T. L., Lee, C. H., Huang, S. P. & Bao, B. Y., Apr 5 2019, In : Cancer Cell International. 19, 1, 87.

Research output: Contribution to journalArticle

Open Access
Circadian Rhythm
Prostatic Neoplasms
Alleles
Computer Simulation
Disease-Free Survival

Glucose-Regulated Protein 94 Modulates the Response of Osteosarcoma to Chemotherapy

Huang, C. Y., Wei, P. L., Wang, J. W., Makondi, P. T., Huang, M. T., Chen, H. A. & Chang, Y. J., Jan 1 2019, In : Disease Markers. 2019, 1 p.

Research output: Contribution to journalArticle

Chemotherapy
Osteosarcoma
gemcitabine
Drug Therapy
Epirubicin

HSPB1 rs2070804 polymorphism is associated with the depth of primary tumor

Hung, C. S., Huang, C. Y., Hsu, Y. W., Makondi, P. T., Chang, W. C., Chang, Y. J., Wang, J. Y. & Wei, P. L., Jan 1 2019, In : Journal of Cellular Biochemistry.

Research output: Contribution to journalArticle

Polymorphism
Tumors
Colorectal Neoplasms
Single Nucleotide Polymorphism
Neoplasms
3 Citations (Scopus)
Propyl Gallate
propyl gallate
autophagy
Autophagy
Cell growth
1 Citation (Scopus)

Six novel immunoglobulin genes as biomarkers for better prognosis in triple-negative breast cancer by gene co-expression network analysis

Hsu, H. M., Chu, C. M., Chang, Y. J., Yu, J. C., Chen, C. T., Jian, C. E., Lee, C. Y., Chiang, Y. T., Chang, C. W. & Chang, Y. T., Dec 1 2019, In : Scientific Reports. 9, 1, 4484.

Research output: Contribution to journalArticle

Open Access
Triple Negative Breast Neoplasms
Immunoglobulin Genes
Neoplasm Genes
Biomarkers
Gene Expression
2018
3 Citations (Scopus)

A common regulatory variant in SLC35B4 influences the recurrence and survival of prostate cancer

Huang, E. Y., Chang, Y. J., Huang, S. P., Lin, V. C., Yu, C. C., Huang, C. Y., Yin, H. L., Chang, T. Y., Lu, T. L. & Bao, B. Y., Jul 1 2018, In : Journal of Cellular and Molecular Medicine. 22, 7, p. 3661-3670 10 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Single Nucleotide Polymorphism
Recurrence
Survival
Glycosyltransferases
Dipeptidyl-Peptidase IV Inhibitors
Keratinocytes
Wound Healing
Adiponectin
Medical problems

Coupling dichloroacetate treatment with curcumin significantly enhances anticancer potential

Kan, P. C., Chang, Y. J., Chien, C. S., Su, C. Y. & Fang, H. W., Nov 1 2018, In : Anticancer Research. 38, 11, p. 6253-6261 9 p.

Research output: Contribution to journalArticle

Curcumin
Alprostadil
Apoptosis
Annexin A5
Volatile Oils
4 Citations (Scopus)
NF-kappa B
Cyclooxygenase 2
Vascular Endothelial Growth Factor A
Neoplasm Metastasis
Proteins
8 Citations (Scopus)

Heat shock protein 27 influences the anti-cancer effect of curcumin in colon cancer cells through ROS production and autophagy activation

Liang, H. H., Huang, C. Y., Chou, C. W., Makondi, P. T., Huang, M. T., Wei, P. L. & Chang, Y. J., Sep 15 2018, In : Life Sciences. 209, p. 43-51 9 p.

Research output: Contribution to journalArticle

HSP27 Heat-Shock Proteins
Curcumin
Autophagy
Colonic Neoplasms
Reactive Oxygen Species

Maspin enhances the anticancer activity of curcumin in hormone-refractory prostate cancer cells

Cheng, W. L., Huang, C. Y., Tai, C. J., Chang, Y. J. & Hung, C. S., Feb 1 2018, In : Anticancer Research. 38, 2, p. 863-870 8 p.

Research output: Contribution to journalArticle

Curcumin
Prostatic Neoplasms
Hormones
Curcuma
Androgens
lipoproteins
Lipoproteins
Psoriasis
interleukins
imiquimod
2 Citations (Scopus)

Prediction of novel target genes and pathways involved in bevacizumab-resistant colorectal cancer

Makondi, P. T., Lee, C. H., Huang, C. Y., Chu, C. M., Chang, Y. J. & Wei, P. L., Jan 1 2018, In : PLoS One. 13, 1, e0189582.

Research output: Contribution to journalArticle

colorectal neoplasms
Colorectal Neoplasms
Genes
prediction
genes
HSP27 Heat-Shock Proteins
Colorectal Neoplasms
Neoplasm Metastasis
Molecules
Proteins
1 Citation (Scopus)
Amphotericin B
Drug Therapy
Neoplasms
Ethanol
Cinnamomum
6 Citations (Scopus)

The application of non-invasive apoptosis detection sensor (NIADS) on histone deacetylation inhibitor (HDACI)-induced breast cancer cell death

Hsu, K. W., Huang, C. Y., Tam, K. W., Lin, C. Y., Huang, L. C., Lin, C. L., Hsieh, W. S., Chi, W. M., Chang, Y. J., Wei, P. L., Chen, S. T. & Lee, C. H., Feb 2 2018, In : International Journal of Molecular Sciences. 19, 2, 452.

Research output: Contribution to journalArticle

apoptosis
Cell death
death
breast
Histones
2017
7 Citations (Scopus)
gemcitabine
Chemotherapy
Tumor Burden
Pancreatic Neoplasms
Heterografts

Hypermethylation of BEND5 contributes to cell proliferation and is a prognostic marker of colorectal cancer

Lin, R. K., Hung, W. Y., Huang, Y. F., Chang, Y. J., Lin, C. H., Chen, W. Y., Chiu, S. F., Chang, S. C. & Tsai, S. F., Jan 1 2017, In : Oncotarget. 8, 69, p. 113431-113443 13 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Cell Proliferation
Tumor Suppressor Genes
Taiwan
Survival
7 Citations (Scopus)
HSP27 Heat-Shock Proteins
Intercellular Signaling Peptides and Proteins
Carrier Proteins
Neoplasm Metastasis
Neoplasms
4 Citations (Scopus)

Prediction of novel target genes and pathways involved in irinotecan-resistant colorectal cancer

Makondi, P. T., Chu, C. M., Wei, P. L. & Chang, Y. J., Jul 1 2017, In : PLoS One. 12, 7, e0180616.

Research output: Contribution to journalArticle

irinotecan
colorectal neoplasms
Colorectal Neoplasms
Fibroblast Growth Factor 2
Genes
2016
13 Citations (Scopus)

Alterations in histone deacetylase 8 lead to cell migration and poor prognosis in breast cancer

Hsieh, C. L., Ma, H. P., Su, C-M., Chang, Y. J., Hung, W. Y., Ho, Y. S., Huang, W. J. & Lin, R. K., Apr 15 2016, In : Life Sciences. 151, p. 7-14 8 p.

Research output: Contribution to journalArticle

Histone Deacetylases
Cell Movement
Breast Neoplasms
Atlases
Assays
7 Citations (Scopus)
Circulating Neoplastic Cells
carbopol 940
Tumors
Colorectal Neoplasms
Assays
7 Citations (Scopus)
gemcitabine
Pancreatic Neoplasms
Nausea
Vomiting
Fluorouracil
1 Citation (Scopus)

GeneGazer: A toolkit integrating two pipelines for personalized profiling and biosignature identification

Luo, J. D., Chang, Y. J., Chang, C. M., You, J. F., Wei, P. L. & Chiou, C. C., Mar 1 2016, In : Cancer Genomics and Proteomics. 13, 2, p. 141-150 10 p.

Research output: Contribution to journalArticle

MicroRNAs
Epigenomics
Gene expression
Pipelines
Genes
12 Citations (Scopus)

Glucose-regulated protein 94 mediates cancer progression via AKT and eNOS in hepatocellular carcinoma

Huang, C. Y., Batzorig, U., Cheng, W. L., Huang, M. T., Chen, W. Y., Wei, P. L. & Chang, Y. J., Apr 1 2016, In : Tumor Biology. 37, 4, p. 4295-4304

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Neoplasms
glucose-regulated proteins
AMP-Activated Protein Kinases
Heterografts
6 Citations (Scopus)

Glucose-regulated protein 94 mediates metastasis by CCT8 and the JNK pathway in hepatocellular carcinoma

Wei, P-L., Huang, C. Y., Tai, C-J., Batzorig, U., Cheng, W. L., Hunag, M. T. & Chang, Y-J., Jun 1 2016, In : Tumor Biology. 37, 6, p. 8219-8227 9 p.

Research output: Contribution to journalArticle

MAP Kinase Signaling System
Hepatocellular Carcinoma
Neoplasm Metastasis
Neoplasms
Wound Healing
1 Citation (Scopus)

Maspin mediates the gemcitabine sensitivity of hormone-independent prostate cancer

Huang, C. Y., Chang, Y. J., Luo, S. D., Uyanga, B., Lin, F. Y., Tai, C. J. & Huang, M. T., Mar 1 2016, In : Tumor Biology. 37, 3, p. 4075-4082

Research output: Contribution to journalArticle

gemcitabine
Prostatic Neoplasms
Hormones
B-Cell Lymphoma
Apoptosis
4 Citations (Scopus)

Silencing A7-nAChR levels increases the sensitivity of gastric cancer cells to ixabepilone treatment

Tu, C. C., Huang, C. Y., Cheng, W. L., Hung, C. S., Chang, Y. J. & Wei, P. L., Jul 1 2016, In : Tumor Biology. 37, 7, p. 9493-9501 9 p.

Research output: Contribution to journalArticle

Cholinergic Receptors
Nicotine
Stomach Neoplasms
Therapeutics
Apoptosis Regulatory Proteins
15 Citations (Scopus)

Targeting TYRO3 inhibits epithelial-mesenchymal transition and increases drug sensitivity in colon cancer

Chien, C-W., Hou, P-C., Wu, H-C., Chang, Y-L., Lin, S-C., Lin, S-C., Lin, B-W., Lee, J-C., Chang, Y-J., Sun, H. S. & Tsai, S-J., Nov 10 2016, In : Oncogene. 35, 45, p. 5872-5881 10 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Colonic Neoplasms
Pharmaceutical Preparations
Oncogenes
Antibodies
8 Citations (Scopus)

The GroEL protein of Porphyromonas gingivalis regulates atherogenic phenomena in endothelial cells mediated by upregulating toll-like receptor 4 expression

Huang, C. Y., Shih, C. M., Tsao, N. W., Lin, Y. W., Shih, C. C., Chiang, K. H., Shyue, S. K., Chang, Y. J., Hsieh, C. K. & Lin, F. Y., 2016, In : American Journal of Translational Research. 8, 2, p. 384-404 21 p.

Research output: Contribution to journalArticle

Chaperonin 60
Porphyromonas gingivalis
Toll-Like Receptor 4
Endothelial cells
Endothelial Cells
8 Citations (Scopus)

The α7-nicotinic acetylcholine receptor mediates the sensitivity of gastric cancer cells to taxanes

Tu, C. C., Huang, C. Y., Cheng, W. L., Hung, C. S., Uyanga, B., Wei, P. L. & Chang, Y. J., Apr 1 2016, In : Tumor Biology. 37, 4, p. 4421-4428

Research output: Contribution to journalArticle

Taxoids
Nicotinic Receptors
Stomach Neoplasms
Paclitaxel
docetaxel
5 Citations (Scopus)

Thrombomodulin influences the survival of patients with non-metastatic colorectal cancer through epithelial-to-mesenchymal transition (EMT)

Chang, Y. J., Cheng, Y. W., Lin, R. K., Huang, C. C., Chen, W. T. L., Ke, T. W. & Wei, P. L., Aug 1 2016, In : PLoS One. 11, 8, e0160550.

Research output: Contribution to journalArticle

Thrombomodulin
Epithelial-Mesenchymal Transition
colorectal neoplasms
Colorectal Neoplasms
Survival
2015
9 Citations (Scopus)

Alpha 7-nicotinic acetylcholine receptor mediates the sensitivity of gastric cancer cells to 5-fluorouracil

Chen, W-Y., Huang, C. Y., Cheng, W. L., Hung, C-S., Huang, M-T., Tai, C-J., Liu, Y-N., Chen, C-L. & Chang, Y-J., Jul 3 2015, (Accepted/In press) In : Tumor Biology. 36, 12, p. 9537-9544

Research output: Contribution to journalArticle

Nicotinic Receptors
Fluorouracil
Stomach Neoplasms
In Situ Nick-End Labeling
Cell Cycle
5 Citations (Scopus)

A novel microtubule-disrupting agent induces endoplasmic reticular stress-mediated cell death in human hepatocellular carcinoma cells

Ho, C. T., Chang, Y. J., Yang, L. X., Wei, P. L., Liu, T. Z. & Liu, J. J., Sep 10 2015, In : PLoS One. 10, 9, e0136340.

Research output: Contribution to journalArticle

Cell death
hepatoma
Microtubules
microtubules
cell death
10 Citations (Scopus)

Cisplatin-, Doxorubicin-, and Docetaxel-Induced Cell Death Promoted by the Aqueous Extract of Solanum nigrum in Human Ovarian Carcinoma Cells

Tai, C. J., Wang, C. W., Chen, C. L., Wang, C. K., Chang, Y. J., Jian, J. Y., Lin, C. S. & Tai, C. J., Nov 1 2015, In : Integrative Cancer Therapies. 14, 6, p. 546-555 10 p.

Research output: Contribution to journalArticle

docetaxel
Solanum nigrum
Doxorubicin
Cisplatin
Ovarian Neoplasms
20 Citations (Scopus)
Colonic Neoplasms
Biomarkers
Neoplasm Metastasis
Vimentin
Cadherins
10 Citations (Scopus)

Glucose-regulated protein 78 mediates the anticancer efficacy of shikonin in hormone-refractory prostate cancer cells

Kuo, L. J., Huang, C. Y., Cheng, W. L., Hung, C. S., Wu, C. T., Lin, F. Y., Chang, Y. J. & Huang, M. T., Jul 29 2015, In : Tumor Biology. 36, 7, p. 5063-5070 8 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Hormones
Small Interfering RNA
Therapeutics
shikonin
6 Citations (Scopus)

Glucose-regulated protein 78 mediates the therapeutic efficacy of 17-DMAG in colon cancer cells

Chang, Y. J., Huang, C. Y., Hung, C. S., Liu, H. H. & Wei, P. L., Jun 11 2015, In : Tumor Biology. 36, 6, p. 4367-4376 10 p.

Research output: Contribution to journalArticle

17-(dimethylaminoethylamino)-17-demethoxygeldanamycin
Colonic Neoplasms
Therapeutics
HT29 Cells
Propidium
12 Citations (Scopus)

GRP78 mediates the therapeutic efficacy of curcumin on colon cancer

Chang, Y-J., Huang, C. Y., Hung, C-S., Chen, W-Y. & Wei, P-L., 2015, In : Tumor Biology. 36, 2, p. 633-641 9 p.

Research output: Contribution to journalArticle

Curcumin
Colonic Neoplasms
HT29 Cells
Therapeutics
In Situ Nick-End Labeling
14 Citations (Scopus)
Solanum nigrum
Doxorubicin
Cisplatin
Hepatocellular Carcinoma
Drug Therapy
8 Citations (Scopus)
Drug Combinations
docetaxel
Carcinoma
Neoplasms
Cisplatin
19 Citations (Scopus)

Prognosis of early-stage hepatocellular carcinoma: The clinical implications of substages of Barcelona Clinic Liver Cancer system based on a cohort of 1265 patients

Kao, W. Y., Chao, Y., Chang, C-C., Li, C. P., Su, C. W., Huo, T. I., Huang, Y. H., Chang, Y. J., Lin, H. C. & Wu, J. C., 2015, In : Medicine (United States). 94, 43, e1929.

Research output: Contribution to journalArticle

Liver Neoplasms
Hepatocellular Carcinoma
varespladib methyl
Survival Rate
Neoplasm Staging
14 Citations (Scopus)

Proteomic characterization of annexin l (ANX1) and heat shock protein 27 (HSP27) as biomarkers for invasive hepatocellular carcinoma cells

Wang, R. C., Huang, C. Y., Pan, T. L., Chen, W. Y., Ho, C. T., Liu, T. Z. & Chang, Y. J., Oct 2 2015, In : PLoS One. 10, 10, e0139232.

Research output: Contribution to journalArticle

HSP27 Heat-Shock Proteins
Annexins
Biomarkers
hepatoma
heat shock proteins
8 Citations (Scopus)

The GroEL protein of Porphyromonas gingivalis accelerates tumor growth by enhancing endothelial progenitor cell function and neovascularization

Lin, F. Y., Huang, C. Y., Lu, H. Y., Shih, C. M., Tsao, N. W., Shyue, S. K., Lin, C. Y., Chang, Y. J., Tsai, C. S., Lin, Y. W. & Lin, S. J., Jun 1 2015, In : Molecular Oral Microbiology. 30, 3, p. 198-216 19 p.

Research output: Contribution to journalArticle

Chaperonin 60
Porphyromonas gingivalis
Growth
Periodontal Diseases
Neoplasms
2014
9 Citations (Scopus)
Camptotheca
Camptothecin
Endometrial Neoplasms
Fruit
Cisplatin
26 Citations (Scopus)

Antroquinonol D, isolated from Antrodia camphorata, with DNA demethylation and anticancer potential

Wang, S. C., Li, Z-H., Hsu, C. H., Chang, Y. J., Chang, M. S., Wang, Y. C., Ho, Y. S., Wen, W. C. & Lin, R. K., Jun 18 2014, In : Journal of Agricultural and Food Chemistry. 62, 24, p. 5625-5635 11 p.

Research output: Contribution to journalArticle

Antrodia
Taiwanofungus camphoratus
methyltransferases
Methyltransferases
breast neoplasms
13 Citations (Scopus)

Glucose-regulated protein 78 mediates hormone-independent prostate cancer progression and metastasis through maspin and COX-2 expression

Wu, C. T., Wang, W. C., Chen, M. F., Su, H. Y., Chen, W. Y., Wu, C. H., Chang, Y. J. & Liu, H. H., Jan 2014, In : Tumor Biology. 35, 1, p. 195-204 10 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Hormones
Neoplasm Metastasis
Cell Movement
SERPIN-B5