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Research Output

  • 2514 Citations
  • 28 h-Index
  • 109 Article
  • 1 Review article
Article
31 Citations (Scopus)
10 Citations (Scopus)
12 Citations (Scopus)
15 Citations (Scopus)
17 Citations (Scopus)

Knockdown of thrombomodulin enhances HCC cell migration through increase of ZEB1 and decrease of E-cadherin gene expression

Huang, M. T., Wei, P. L., Liu, J. J., Liu, D. Z., Huang, H. C., An, J., Wu, C. C., Wu, C. H., Ho, Y. S., Yang, Y. Y. & Chang, Y. J., Dec 2010, In : Annals of Surgical Oncology. 17, 12, p. 3379-3385 7 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Knockdown survivin expression reduces the efficacy of curcumin treatment in hepatocellular carcinoma cells

Hung, C. S., Liu, H. H., Huang, M. T., Cheng, C. W., Kuo, L. J., Ho, Y. S., Wu, C. H., Chen, C. M., Wei, P. L. & Chang, Y. J., Oct 2012, In : Annals of Surgical Oncology. 19, 11, p. 3547-3555 9 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Maspin enhances the anticancer activity of curcumin in hormone-refractory prostate cancer cells

Cheng, W. L., Huang, C. Y., Tai, C. J., Chang, Y. J. & Hung, C. S., Feb 1 2018, In : Anticancer Research. 38, 2, p. 863-870 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Maspin mediates the gemcitabine sensitivity of hormone-independent prostate cancer

Huang, C. Y., Chang, Y. J., Luo, S. D., Uyanga, B., Lin, F. Y., Tai, C. J. & Huang, M. T., Mar 1 2016, In : Tumor Biology. 37, 3, p. 4075-4082

Research output: Contribution to journalArticle

2 Citations (Scopus)

MicroRNA-200a/b influenced the therapeutic effects of curcumin in hepatocellular carcinoma (HCC) cells

Liang, H. H., Wei, P. L., Hung, C. S., Wu, C. T., Wang, W., Huang, M. T. & Chang, Y. J., 2013, In : Tumor Biology. 34, 5, p. 3209-3218 10 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
39 Citations (Scopus)
35 Citations (Scopus)

Mutation of human plasminogen kringle 1-5 enhances anti-angiogenic action via increased interaction with integrin αvβ3

Chang, P. C., Chang, Y. J., Wu, H. L., Chang, C. W., Lin, C. I., Wang, W. C. & Shi, G. Y., Apr 2008, In : Thrombosis and Haemostasis. 99, 4, p. 729-738 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

New therapeutic approach to suppress castration-resistant prostate cancer using ASC-J9 via targeting androgen receptor in selective prostate cells

Lai, K. P., Huang, C. K., Chang, Y. J., Chung, C. Y., Yamashita, S., Li, L., Lee, S. O., Yeh, S. & Chang, C., Feb 2013, In : American Journal of Pathology. 182, 2, p. 460-473 14 p.

Research output: Contribution to journalArticle

57 Citations (Scopus)

Nicotine enhances colon cancer cell migration by induction of fibronectin

Wei, P. L., Kuo, L. J., Huang, M. T., Ting, W. C., Ho, Y. S., Wang, W., An, J. & Chang, Y. J., Jun 2011, In : Annals of Surgical Oncology. 18, 6, p. 1782-1790 9 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)

Nicotine-induced human breast cancer cell proliferation attenuated by garcinol through down-regulation of the nicotinic receptor and cyclin D3 proteins

Chen, C. S., Lee, C-H., Hsieh, C. D., Ho, C. T., Pan, M. H., Huang, C. S., Tu, S-H., Wang, Y. J., Chen, L-C., Chang, Y-J., Wei, P-L., Yang, Y-Y., Wu, C-H. & Ho, Y-S., Jan 2011, In : Breast Cancer Research and Treatment. 125, 1, p. 73-87 15 p.

Research output: Contribution to journalArticle

84 Citations (Scopus)

Nicotine promotes cell migration through alpha7 nicotinic acetylcholine receptor in gastric cancer cells

Lien, Y. C., Wang, W., Kuo, L. J., Liu, J. J., Wei, P. L., Ho, Y. S., Ting, W. C., Wu, C. H. & Chang, Y. J., Sep 2011, In : Annals of Surgical Oncology. 18, 9, p. 2671-2679 9 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)
24 Citations (Scopus)

Normoxically overexpressed hypoxia inducible factor 1-alpha is involved in arsenic trioxide resistance acquisition in hepatocellular carcinoma

Tung, J. N., Cheng, Y. W., Hsu, C. H., Liu, T. Z., Hsieh, P. Y., Ting, L. L., Ko, H. L., Chang, Y. J., Chiou, J. F. & Wu, A. T. H., May 2011, In : Annals of Surgical Oncology. 18, 5, p. 1492-1500 9 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Oligozoospermia with normal fertility in male mice lacking the androgen receptor in testis peritubular myoid cells

Zhang, C., Yeh, S., Chen, Y. T., Wu, C. C., Chuang, K. H., Lin, H. Y., Wang, R. S., Chang, Y. J., Mendis-Handagama, C., Hu, L., Lardy, H. & Chang, C., Nov 21 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 47, p. 17718-17723 6 p.

Research output: Contribution to journalArticle

96 Citations (Scopus)

Oncological and functional outcomes of intersphincteric resection for low rectal cancer

Kuo, L. J., Hung, C. S., Wu, C. H., Wang, W., Tam, K. W., Liang, H. H., Chang, Y. J. & Wei, P. L., Sep 2011, In : Journal of Surgical Research. 170, 1, p. e93-e98

Research output: Contribution to journalArticle

33 Citations (Scopus)

Overexpression and activation of the α9-nicotinic receptor during tumorigenesis in human breast epithelial cells

Lee, C. H., Huang, C. S., Chen, C. S., Tu, S. H., Wang, Y. J., Chang, Y. J., Tam, K. W., Wei, P. L., Cheng, T. C., Chu, J. S., Chen, L. C., Wu, C. H. & Ho, Y. S., Sep 8 2010, In : Journal of the National Cancer Institute. 102, 17, p. 1322-1335 14 p.

Research output: Contribution to journalArticle

105 Citations (Scopus)
3 Citations (Scopus)
9 Citations (Scopus)

Prediction of novel target genes and pathways involved in bevacizumab-resistant colorectal cancer

Makondi, P. T., Lee, C. H., Huang, C. Y., Chu, C. M., Chang, Y. J. & Wei, P. L., Jan 1 2018, In : PLoS One. 13, 1, e0189582.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Prediction of novel target genes and pathways involved in irinotecan-resistant colorectal cancer

Makondi, P. T., Chu, C. M., Wei, P. L. & Chang, Y. J., Jul 1 2017, In : PLoS One. 12, 7, e0180616.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Prognosis of early-stage hepatocellular carcinoma: The clinical implications of substages of Barcelona Clinic Liver Cancer system based on a cohort of 1265 patients

Kao, W. Y., Chao, Y., Chang, C-C., Li, C. P., Su, C. W., Huo, T. I., Huang, Y. H., Chang, Y. J., Lin, H. C. & Wu, J. C., 2015, In : Medicine (United States). 94, 43, e1929.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Promotion of bladder cancer development and progression by androgen receptor signals

Miyamoto, H., Yang, Z., Chen, Y. T., Ishiguro, H., Uemura, H., Kubota, Y., Nagashima, Y., Chang, Y. J., Hu, Y. C., Tsai, M. Y., Yeh, S., Messing, E. M. & Chang, C., Apr 4 2007, In : Journal of the National Cancer Institute. 99, 7, p. 558-568 11 p.

Research output: Contribution to journalArticle

265 Citations (Scopus)
4 Citations (Scopus)

Proteomic characterization of annexin l (ANX1) and heat shock protein 27 (HSP27) as biomarkers for invasive hepatocellular carcinoma cells

Wang, R. C., Huang, C. Y., Pan, T. L., Chen, W. Y., Ho, C. T., Liu, T. Z. & Chang, Y. J., Oct 2 2015, In : PLoS One. 10, 10, e0139232.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Role of DNA methyltransferase 1 in hormone-resistant prostate cancer

Chen, M. F., Chen, W. C., Chang, Y. J., Wu, C. F. & Wu, C. T., Sep 2010, In : Journal of Molecular Medicine. 88, 9, p. 953-962 10 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Shikonin suppresses the migratory ability of hepatocellular carcinoma cells

Wei, P. L., Tu, C. C., Chen, C. H., Ho, Y. S., Wu, C. T., Su, H. Y., Chen, W. Y., Liu, J. J. & Chang, Y. J., Aug 28 2013, In : Journal of Agricultural and Food Chemistry. 61, 34, p. 8191-8197 7 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Silencing A7-nAChR levels increases the sensitivity of gastric cancer cells to ixabepilone treatment

Tu, C. C., Huang, C. Y., Cheng, W. L., Hung, C. S., Chang, Y. J. & Wei, P. L., Jul 1 2016, In : Tumor Biology. 37, 7, p. 9493-9501 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
25 Citations (Scopus)

Silencing survivin activates autophagy as an alternative survival pathway in HCC cells

Chang, Y. J., Li, L. T., Chen, H. A., Hung, C. S. & Wei, P. L., Jul 10 2014, In : Tumor Biology. 35, 10, p. 9957-9966 10 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Six novel immunoglobulin genes as biomarkers for better prognosis in triple-negative breast cancer by gene co-expression network analysis

Hsu, H. M., Chu, C. M., Chang, Y. J., Yu, J. C., Chen, C. T., Jian, C. E., Lee, C. Y., Chiang, Y. T., Chang, C. W. & Chang, Y. T., Dec 1 2019, In : Scientific Reports. 9, 1, 4484.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Subfertility with defective folliculogenesis in female mice lacking testicular orphan nuclear receptor 4

Chen, L. M., Wang, R. S., Lee, Y. F., Liu, N. C., Chang, Y. J., Wu, C. C., Xie, S., Hung, Y. C. & Chang, C., Apr 2008, In : Molecular Endocrinology. 22, 4, p. 858-867 10 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Suppression of androgen receptor transactivation and prostate cancer cell growth by heterogeneous nuclear ribonucleoprotein A1 via interaction with androgen receptor coregulator ARA54

Yang, Z., Chang, Y. J., Miyamoto, H., Yeh, S., Yao, J. L., Di Sant'Agnese, P. A., Tsai, M. Y. & Chang, C., Mar 2007, In : Endocrinology. 148, 3, p. 1340-1349 10 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
22 Citations (Scopus)

Survivin-mediated therapeutic efficacy of gemcitabine through glucose-regulated protein 78 in hepatocellular carcinoma

Hung, C. S., Lin, S. F., Liu, H. H., Kuo, L. J., Li, L. T., Su, H. Y., Liew, P. L., Lin, F. Y., Wei, P. L., Liu, D. Z. & Chang, Y. J., Aug 2012, In : Annals of Surgical Oncology. 19, 8, p. 2744-2752 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
1 Citation (Scopus)

Targeting TYRO3 inhibits epithelial-mesenchymal transition and increases drug sensitivity in colon cancer

Chien, C-W., Hou, P-C., Wu, H-C., Chang, Y-L., Lin, S-C., Lin, S-C., Lin, B-W., Lee, J-C., Chang, Y-J., Sun, H. S. & Tsai, S-J., Nov 10 2016, In : Oncogene. 35, 45, p. 5872-5881 10 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Tea polyphenol (-)-epigallocatechin-3-gallate inhibits nicotine- and estrogen-induced α9-nicotinic acetylcholine receptor upregulation in human breast cancer cells

Tu, S. H., Ku, C. Y., Ho, C. T., Chen, C. S., Huang, C. S., Lee, C. H., Chen, L. C., Pan, M. H., Chang, H. W., Chang, C. H., Chang, Y. J., Wei, P. L., Wu, C. H. & Ho, Y. S., Mar 2011, In : Molecular Nutrition and Food Research. 55, 3, p. 455-466 12 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)
12 Citations (Scopus)

The application of non-invasive apoptosis detection sensor (NIADS) on histone deacetylation inhibitor (HDACI)-induced breast cancer cell death

Hsu, K. W., Huang, C. Y., Tam, K. W., Lin, C. Y., Huang, L. C., Lin, C. L., Hsieh, W. S., Chi, W. M., Chang, Y. J., Wei, P. L., Chen, S. T. & Lee, C. H., Feb 2 2018, In : International Journal of Molecular Sciences. 19, 2, 452.

Research output: Contribution to journalArticle

6 Citations (Scopus)

The C-terminal domain of thrombomodulin regulates monocyte migration with interleukin-6 stimulation

Lin, Y. W., Huang, C. Y., Shih, C. M., Chang, W. L., Shyue, S. K., Tsai, Y. T., Lin, C. Y., Lee, C. Y., Chang, Y. J., Chang, N. C., Lin, F. Y. & Tsai, C. S., 2014, In : European Journal of Inflammation. 12, 1, p. 27-39 13 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

The distinct roles that Gln-192 and Glu-217 of factor IX play in selectivity for macromolecular substrates and inhibitors

Hsu, Y. C., Hamaguchi, N., Chang, Y. J. & Lin, S. W., Sep 18 2001, In : Biochemistry. 40, 37, p. 11261-11269 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

The GroEL protein of Porphyromonas gingivalis accelerates tumor growth by enhancing endothelial progenitor cell function and neovascularization

Lin, F. Y., Huang, C. Y., Lu, H. Y., Shih, C. M., Tsao, N. W., Shyue, S. K., Lin, C. Y., Chang, Y. J., Tsai, C. S., Lin, Y. W. & Lin, S. J., Jun 1 2015, In : Molecular Oral Microbiology. 30, 3, p. 198-216 19 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)