If you made any changes in Pure these will be visible here soon.

Research Output

  • 2476 Citations
  • 28 h-Index
  • 109 Article
  • 1 Review article

A common regulatory variant in SLC35B4 influences the recurrence and survival of prostate cancer

Huang, E. Y., Chang, Y. J., Huang, S. P., Lin, V. C., Yu, C. C., Huang, C. Y., Yin, H. L., Chang, T. Y., Lu, T. L. & Bao, B. Y., Jul 1 2018, In : Journal of Cellular and Molecular Medicine. 22, 7, p. 3661-3670 10 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
1 Citation (Scopus)

Alpha 7-nicotinic acetylcholine receptor mediates the sensitivity of gastric cancer cells to 5-fluorouracil

Chen, W-Y., Huang, C. Y., Cheng, W. L., Hung, C-S., Huang, M-T., Tai, C-J., Liu, Y-N., Chen, C-L. & Chang, Y-J., Jul 3 2015, (Accepted/In press) In : Tumor Biology. 36, 12, p. 9537-9544

Research output: Contribution to journalArticle

12 Citations (Scopus)

Alterations in histone deacetylase 8 lead to cell migration and poor prognosis in breast cancer

Hsieh, C. L., Ma, H. P., Su, C-M., Chang, Y. J., Hung, W. Y., Ho, Y. S., Huang, W. J. & Lin, R. K., Apr 15 2016, In : Life Sciences. 151, p. 7-14 8 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

A novel microtubule-disrupting agent induces endoplasmic reticular stress-mediated cell death in human hepatocellular carcinoma cells

Ho, C. T., Chang, Y. J., Yang, L. X., Wei, P. L., Liu, T. Z. & Liu, J. J., Sep 10 2015, In : PLoS One. 10, 9, e0136340.

Research output: Contribution to journalArticle

8 Citations (Scopus)
11 Citations (Scopus)

Antroquinonol D, isolated from Antrodia camphorata, with DNA demethylation and anticancer potential

Wang, S. C., Li, Z-H., Hsu, C. H., Chang, Y. J., Chang, M. S., Wang, Y. C., Ho, Y. S., Wen, W. C. & Lin, R. K., Jun 18 2014, In : Journal of Agricultural and Food Chemistry. 62, 24, p. 5625-5635 11 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)
16 Citations (Scopus)
41 Citations (Scopus)

Ardisianone, a natural benzoquinone, efficiently induces apoptosis in human hormone-refractory prostate cancers through mitochondrial damage stress and survivin downregulation

Yu, C. C., Wu, P. J., Hsu, J. L., Ho, Y. F., Hsu, L. C., Chang, Y. J., Chang, H. S., Chen, I. S. & Guh, J. H., Jan 2013, In : Prostate. 73, 2, p. 133-145 13 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

ASC-J9 ameliorates spinal and bulbar muscular atrophy phenotype via degradation of androgen receptor

Yang, Z., Chang, Y. J., Yu, I. C., Yeh, S., Wu, C. C., Miyamoto, H., Merry, D. E., Sobue, G., Chen, L. M., Chang, S. S. & Chang, C., Mar 2007, In : Nature Medicine. 13, 3, p. 348-353 6 p.

Research output: Contribution to journalArticle

120 Citations (Scopus)
7 Citations (Scopus)

Bromelain inhibits the ability of colorectal cancer cells to proliferate via activation of ROS production and autophagy

Chang, T. C., Wei, P. L., Makondi, P. T., Chen, W. T., Huang, C. Y. & Chang, Y. J., Jan 1 2019, In : PLoS One. 14, 1, e0210274.

Research output: Contribution to journalArticle

5 Citations (Scopus)
28 Citations (Scopus)
7 Citations (Scopus)

Cisplatin-, Doxorubicin-, and Docetaxel-Induced Cell Death Promoted by the Aqueous Extract of Solanum nigrum in Human Ovarian Carcinoma Cells

Tai, C. J., Wang, C. W., Chen, C. L., Wang, C. K., Chang, Y. J., Jian, J. Y., Lin, C. S. & Tai, C. J., Nov 1 2015, In : Integrative Cancer Therapies. 14, 6, p. 546-555 10 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
9 Citations (Scopus)
8 Citations (Scopus)
8 Citations (Scopus)

Coupling dichloroacetate treatment with curcumin significantly enhances anticancer potential

Kan, P. C., Chang, Y. J., Chien, C. S., Su, C. Y. & Fang, H. W., Nov 1 2018, In : Anticancer Research. 38, 11, p. 6253-6261 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Crosstalk between nicotine and estrogen-induced estrogen receptor activation induces α9-nicotinic acetylcholine receptor expression in human breast cancer cells

Lee, C. H., Chang, Y. C., Chen, C. S., Tu, S. H., Wang, Y. J., Chen, L. C., Chang, Y. J., Wei, P. L., Chang, H. W., Chang, C. H., Huang, C. S., Wu, C. H. & Ho, Y. S., Sep 2011, In : Breast Cancer Research and Treatment. 129, 2, p. 331-345 15 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)
2 Citations (Scopus)

Discontinuous residues of factor IX constitute a surface for binding the anti-factor IX monoclonal antibody A-5

Chang, Y. J., Wu, H. L., Hsu, Y. C., Hamaguchi, N., Shi, G. Y., Shen, M. C. & Lin, S. W., 2003, In : Thrombosis Research. 111, 4-5, p. 293-299 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Engineered recombinant factor VII Q217 variants with altered inhibitor specificities

Chang, Y. J., Hamaguchi, N., Chang, S. C., Ruf, W., Shen, M. C. & Lin, S. W., Aug 24 1999, In : Biochemistry. 38, 34, p. 10940-10948 9 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Enhancement of temozolomide-induced apoptosis by valproic acid in human glioma cell lines through redox regulation

Chen, C. H., Chang, Y. J., Ku, M. S. B., Chung, K. T. & Yang, J. T., Mar 2011, In : Journal of Molecular Medicine. 89, 3, p. 303-315 13 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Evidence of human thrombomodulin domain as a novel angiogenic factor

Shi, C. S., Shi, G. Y., Chang, Y. S., Han, H. S., Kuo, C. H., Liu, C., Huang, H. C., Chang, Y. J., Chen, P. S. & Wu, H. L., Apr 5 2005, In : Circulation. 111, 13, p. 1627-1636 10 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)
14 Citations (Scopus)

GeneGazer: A toolkit integrating two pipelines for personalized profiling and biosignature identification

Luo, J. D., Chang, Y. J., Chang, C. M., You, J. F., Wei, P. L. & Chiou, C. C., Mar 1 2016, In : Cancer Genomics and Proteomics. 13, 2, p. 141-150 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Genetic variants in the circadian rhythm pathway as indicators of prostate cancer progression

Yu, C. C., Chen, L. C., Chiou, C. Y., Chang, Y. J., Lin, V. C., Huang, C. Y., Lin, I. L., Chang, T. Y., Lu, T. L., Lee, C. H., Huang, S. P. & Bao, B. Y., Apr 5 2019, In : Cancer Cell International. 19, 1, 87.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Glucose-regulated protein 78 (GRP78) mediated the efficacy to curcumin treatment on hepatocellular carcinoma

Chang, Y. J., Tai, C. J., Kuo, L. J., Wei, P. L., Liang, H. H., Liu, T. Z., Wang, W., Tai, C. J., Ho, Y. S., Wu, C. H. & Huang, M. T., Aug 2011, In : Annals of Surgical Oncology. 18, 8, p. 2395-2403 9 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)
21 Citations (Scopus)

Glucose-Regulated protein 78 (GRP78) silencing enhances cell migration but does not influence cell proliferation in hepatocellular carcinoma

Chang, Y-J., Chiu, C. C., Wu, C-H., An, J., Wu, C. C., Liu, T. Z., Wei, P-L. & Huang, M-T., Jun 2010, In : Annals of Surgical Oncology. 17, 6, p. 1703-1709 7 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Glucose-regulated protein 78 Is a novel contributor to acquisition of resistance to sorafenib in hepatocellular carcinoma

Chiou, J-F., Tai, C-J., Huang, M-T., Wei, P-L., Wang, Y. H., An, J., Wu, C-H., Liu, T. Z. & Chang, Y-J., Feb 2010, In : Annals of Surgical Oncology. 17, 2, p. 603-612 10 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

Glucose-regulated protein 78 mediates hormone-independent prostate cancer progression and metastasis through maspin and COX-2 expression

Wu, C. T., Wang, W. C., Chen, M. F., Su, H. Y., Chen, W. Y., Wu, C. H., Chang, Y. J. & Liu, H. H., Jan 2014, In : Tumor Biology. 35, 1, p. 195-204 10 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Glucose-regulated protein 78 mediates the anticancer efficacy of shikonin in hormone-refractory prostate cancer cells

Kuo, L. J., Huang, C. Y., Cheng, W. L., Hung, C. S., Wu, C. T., Lin, F. Y., Chang, Y. J. & Huang, M. T., Jul 29 2015, In : Tumor Biology. 36, 7, p. 5063-5070 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Glucose-regulated protein 78 mediates the therapeutic efficacy of 17-DMAG in colon cancer cells

Chang, Y. J., Huang, C. Y., Hung, C. S., Liu, H. H. & Wei, P. L., Jun 11 2015, In : Tumor Biology. 36, 6, p. 4367-4376 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
19 Citations (Scopus)

Glucose-regulated protein 94 mediates cancer progression via AKT and eNOS in hepatocellular carcinoma

Huang, C. Y., Batzorig, U., Cheng, W. L., Huang, M. T., Chen, W. Y., Wei, P. L. & Chang, Y. J., Apr 1 2016, In : Tumor Biology. 37, 4, p. 4295-4304

Research output: Contribution to journalArticle

12 Citations (Scopus)

Glucose-regulated protein 94 mediates metastasis by CCT8 and the JNK pathway in hepatocellular carcinoma

Wei, P-L., Huang, C. Y., Tai, C-J., Batzorig, U., Cheng, W. L., Hunag, M. T. & Chang, Y-J., Jun 1 2016, In : Tumor Biology. 37, 6, p. 8219-8227 9 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
5 Citations (Scopus)

Glucose-Regulated Protein 94 Modulates the Response of Osteosarcoma to Chemotherapy

Huang, C. Y., Wei, P. L., Wang, J. W., Makondi, P. T., Huang, M. T., Chen, H. A. & Chang, Y. J., Jan 1 2019, In : Disease Markers. 2019, 1 p.

Research output: Contribution to journalArticle

Glucose-regulated protein 94 modulates the therapeutic efficacy to taxane in cervical cancer cells

Tai, C. J., Wang, J. W., Su, H. Y., Tai, C. J., Wang, C. K., Wu, C. T., Lien, Y. C. & Chang, Y. J., Jan 2014, In : Tumor Biology. 35, 1, p. 403-410 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
30 Citations (Scopus)

GroEL1, from chlamydia pneumoniae, induces vascular adhesion molecule 1 expression by p37AUF1 in endothelial cells and hypercholesterolemic rabbit

Huang, C. Y., Shih, C. M., Tsao, N. W., Chen, Y. H., Li, C. Y., Chang, Y. J., Chang, N. C., Ou, K. L., Lin, C. Y., Lin, Y. W., Nien, C. H. & Lin, F. Y., Aug 10 2012, In : PLoS One. 7, 8, e42808.

Research output: Contribution to journalArticle

10 Citations (Scopus)

GRP78 knockdown enhances apoptosis via the down-regulation of oxidative stress and akt pathway after epirubicin treatment in colon cancer DLD-1 cells

Chang, Y. J., Huang, Y. P., Li, Z. L. & Chen, C. H., Apr 18 2012, In : PLoS One. 7, 4, e35123.

Research output: Contribution to journalArticle

48 Citations (Scopus)

GRP78 mediates the therapeutic efficacy of curcumin on colon cancer

Chang, Y-J., Huang, C. Y., Hung, C-S., Chen, W-Y. & Wei, P-L., 2015, In : Tumor Biology. 36, 2, p. 633-641 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Heat shock protein 27 influences the anti-cancer effect of curcumin in colon cancer cells through ROS production and autophagy activation

Liang, H. H., Huang, C. Y., Chou, C. W., Makondi, P. T., Huang, M. T., Wei, P. L. & Chang, Y. J., Sep 15 2018, In : Life Sciences. 209, p. 43-51 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

High-level expression of CXCR4 in breast cancer is associated with early distant and bone metastases

Hung, C-S., Su, H. Y., Liang, H-H., Lai, C. W., Chang, Y-C., Ho, Y-S., Wu, C-H., Ho, J-D., Wei, P-L. & Chang, Y-J., 2014, In : Tumor Biology. 35, 2, p. 1581-1588 8 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

HSPB1 rs2070804 polymorphism is associated with the depth of primary tumor

Hung, C. S., Huang, C. Y., Hsu, Y. W., Makondi, P. T., Chang, W. C., Chang, Y. J., Wang, J. Y. & Wei, P. L., Jan 1 2020, In : Journal of Cellular Biochemistry. 121, 1, p. 63-69 7 p.

Research output: Contribution to journalArticle