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Research Output

  • 2476 Citations
  • 28 h-Index
  • 109 Article
  • 1 Review article
2013

Shikonin suppresses the migratory ability of hepatocellular carcinoma cells

Wei, P. L., Tu, C. C., Chen, C. H., Ho, Y. S., Wu, C. T., Su, H. Y., Chen, W. Y., Liu, J. J. & Chang, Y. J., Aug 28 2013, In : Journal of Agricultural and Food Chemistry. 61, 34, p. 8191-8197 7 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Thrombomodulin mediates the progression of epithelial ovarian cancer cells

Chen, L. M., Wang, W., Lee, J. C., Chiu, F. H., Wu, C. T., Tai, C. J., Wang, C. K., Tai, C. J., Huang, M. T. & Chang, Y. J., Dec 2013, In : Tumor Biology. 34, 6, p. 3743-3751 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

UVB Irradiation Regulates ERK1/2- and p53-Dependent Thrombomodulin Expression in Human Keratinocytes

Huang, H. C., Chang, T. M., Chang, Y. J. & Wen, H. Y., Jul 2 2013, In : PLoS One. 8, 7, e67632.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2014
11 Citations (Scopus)

Antroquinonol D, isolated from Antrodia camphorata, with DNA demethylation and anticancer potential

Wang, S. C., Li, Z-H., Hsu, C. H., Chang, Y. J., Chang, M. S., Wang, Y. C., Ho, Y. S., Wen, W. C. & Lin, R. K., Jun 18 2014, In : Journal of Agricultural and Food Chemistry. 62, 24, p. 5625-5635 11 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Glucose-regulated protein 78 mediates hormone-independent prostate cancer progression and metastasis through maspin and COX-2 expression

Wu, C. T., Wang, W. C., Chen, M. F., Su, H. Y., Chen, W. Y., Wu, C. H., Chang, Y. J. & Liu, H. H., Jan 2014, In : Tumor Biology. 35, 1, p. 195-204 10 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Glucose-regulated protein 94 modulates the therapeutic efficacy to taxane in cervical cancer cells

Tai, C. J., Wang, J. W., Su, H. Y., Tai, C. J., Wang, C. K., Wu, C. T., Lien, Y. C. & Chang, Y. J., Jan 2014, In : Tumor Biology. 35, 1, p. 403-410 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

High-level expression of CXCR4 in breast cancer is associated with early distant and bone metastases

Hung, C-S., Su, H. Y., Liang, H-H., Lai, C. W., Chang, Y-C., Ho, Y-S., Wu, C-H., Ho, J-D., Wei, P-L. & Chang, Y-J., 2014, In : Tumor Biology. 35, 2, p. 1581-1588 8 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Silencing survivin activates autophagy as an alternative survival pathway in HCC cells

Chang, Y. J., Li, L. T., Chen, H. A., Hung, C. S. & Wei, P. L., Jul 10 2014, In : Tumor Biology. 35, 10, p. 9957-9966 10 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

The C-terminal domain of thrombomodulin regulates monocyte migration with interleukin-6 stimulation

Lin, Y. W., Huang, C. Y., Shih, C. M., Chang, W. L., Shyue, S. K., Tsai, Y. T., Lin, C. Y., Lee, C. Y., Chang, Y. J., Chang, N. C., Lin, F. Y. & Tsai, C. S., 2014, In : European Journal of Inflammation. 12, 1, p. 27-39 13 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
3 Citations (Scopus)
2015

Alpha 7-nicotinic acetylcholine receptor mediates the sensitivity of gastric cancer cells to 5-fluorouracil

Chen, W-Y., Huang, C. Y., Cheng, W. L., Hung, C-S., Huang, M-T., Tai, C-J., Liu, Y-N., Chen, C-L. & Chang, Y-J., Jul 3 2015, (Accepted/In press) In : Tumor Biology. 36, 12, p. 9537-9544

Research output: Contribution to journalArticle

12 Citations (Scopus)

A novel microtubule-disrupting agent induces endoplasmic reticular stress-mediated cell death in human hepatocellular carcinoma cells

Ho, C. T., Chang, Y. J., Yang, L. X., Wei, P. L., Liu, T. Z. & Liu, J. J., Sep 10 2015, In : PLoS One. 10, 9, e0136340.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Cisplatin-, Doxorubicin-, and Docetaxel-Induced Cell Death Promoted by the Aqueous Extract of Solanum nigrum in Human Ovarian Carcinoma Cells

Tai, C. J., Wang, C. W., Chen, C. L., Wang, C. K., Chang, Y. J., Jian, J. Y., Lin, C. S. & Tai, C. J., Nov 1 2015, In : Integrative Cancer Therapies. 14, 6, p. 546-555 10 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
21 Citations (Scopus)

Glucose-regulated protein 78 mediates the anticancer efficacy of shikonin in hormone-refractory prostate cancer cells

Kuo, L. J., Huang, C. Y., Cheng, W. L., Hung, C. S., Wu, C. T., Lin, F. Y., Chang, Y. J. & Huang, M. T., Jul 29 2015, In : Tumor Biology. 36, 7, p. 5063-5070 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Glucose-regulated protein 78 mediates the therapeutic efficacy of 17-DMAG in colon cancer cells

Chang, Y. J., Huang, C. Y., Hung, C. S., Liu, H. H. & Wei, P. L., Jun 11 2015, In : Tumor Biology. 36, 6, p. 4367-4376 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

GRP78 mediates the therapeutic efficacy of curcumin on colon cancer

Chang, Y-J., Huang, C. Y., Hung, C-S., Chen, W-Y. & Wei, P-L., 2015, In : Tumor Biology. 36, 2, p. 633-641 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
15 Citations (Scopus)
8 Citations (Scopus)

Prognosis of early-stage hepatocellular carcinoma: The clinical implications of substages of Barcelona Clinic Liver Cancer system based on a cohort of 1265 patients

Kao, W. Y., Chao, Y., Chang, C-C., Li, C. P., Su, C. W., Huo, T. I., Huang, Y. H., Chang, Y. J., Lin, H. C. & Wu, J. C., 2015, In : Medicine (United States). 94, 43, e1929.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Proteomic characterization of annexin l (ANX1) and heat shock protein 27 (HSP27) as biomarkers for invasive hepatocellular carcinoma cells

Wang, R. C., Huang, C. Y., Pan, T. L., Chen, W. Y., Ho, C. T., Liu, T. Z. & Chang, Y. J., Oct 2 2015, In : PLoS One. 10, 10, e0139232.

Research output: Contribution to journalArticle

15 Citations (Scopus)

The GroEL protein of Porphyromonas gingivalis accelerates tumor growth by enhancing endothelial progenitor cell function and neovascularization

Lin, F. Y., Huang, C. Y., Lu, H. Y., Shih, C. M., Tsao, N. W., Shyue, S. K., Lin, C. Y., Chang, Y. J., Tsai, C. S., Lin, Y. W. & Lin, S. J., Jun 1 2015, In : Molecular Oral Microbiology. 30, 3, p. 198-216 19 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2016

Alterations in histone deacetylase 8 lead to cell migration and poor prognosis in breast cancer

Hsieh, C. L., Ma, H. P., Su, C-M., Chang, Y. J., Hung, W. Y., Ho, Y. S., Huang, W. J. & Lin, R. K., Apr 15 2016, In : Life Sciences. 151, p. 7-14 8 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
9 Citations (Scopus)
8 Citations (Scopus)
8 Citations (Scopus)

GeneGazer: A toolkit integrating two pipelines for personalized profiling and biosignature identification

Luo, J. D., Chang, Y. J., Chang, C. M., You, J. F., Wei, P. L. & Chiou, C. C., Mar 1 2016, In : Cancer Genomics and Proteomics. 13, 2, p. 141-150 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Glucose-regulated protein 94 mediates cancer progression via AKT and eNOS in hepatocellular carcinoma

Huang, C. Y., Batzorig, U., Cheng, W. L., Huang, M. T., Chen, W. Y., Wei, P. L. & Chang, Y. J., Apr 1 2016, In : Tumor Biology. 37, 4, p. 4295-4304

Research output: Contribution to journalArticle

12 Citations (Scopus)

Glucose-regulated protein 94 mediates metastasis by CCT8 and the JNK pathway in hepatocellular carcinoma

Wei, P-L., Huang, C. Y., Tai, C-J., Batzorig, U., Cheng, W. L., Hunag, M. T. & Chang, Y-J., Jun 1 2016, In : Tumor Biology. 37, 6, p. 8219-8227 9 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Maspin mediates the gemcitabine sensitivity of hormone-independent prostate cancer

Huang, C. Y., Chang, Y. J., Luo, S. D., Uyanga, B., Lin, F. Y., Tai, C. J. & Huang, M. T., Mar 1 2016, In : Tumor Biology. 37, 3, p. 4075-4082

Research output: Contribution to journalArticle

2 Citations (Scopus)

Silencing A7-nAChR levels increases the sensitivity of gastric cancer cells to ixabepilone treatment

Tu, C. C., Huang, C. Y., Cheng, W. L., Hung, C. S., Chang, Y. J. & Wei, P. L., Jul 1 2016, In : Tumor Biology. 37, 7, p. 9493-9501 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Targeting TYRO3 inhibits epithelial-mesenchymal transition and increases drug sensitivity in colon cancer

Chien, C-W., Hou, P-C., Wu, H-C., Chang, Y-L., Lin, S-C., Lin, S-C., Lin, B-W., Lee, J-C., Chang, Y-J., Sun, H. S. & Tsai, S-J., Nov 10 2016, In : Oncogene. 35, 45, p. 5872-5881 10 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

The GroEL protein of Porphyromonas gingivalis regulates atherogenic phenomena in endothelial cells mediated by upregulating toll-like receptor 4 expression

Huang, C. Y., Shih, C. M., Tsao, N. W., Lin, Y. W., Shih, C. C., Chiang, K. H., Shyue, S. K., Chang, Y. J., Hsieh, C. K. & Lin, F. Y., 2016, In : American Journal of Translational Research. 8, 2, p. 384-404 21 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

The α7-nicotinic acetylcholine receptor mediates the sensitivity of gastric cancer cells to taxanes

Tu, C. C., Huang, C. Y., Cheng, W. L., Hung, C. S., Uyanga, B., Wei, P. L. & Chang, Y. J., Apr 1 2016, In : Tumor Biology. 37, 4, p. 4421-4428

Research output: Contribution to journalArticle

10 Citations (Scopus)

Thrombomodulin influences the survival of patients with non-metastatic colorectal cancer through epithelial-to-mesenchymal transition (EMT)

Chang, Y. J., Cheng, Y. W., Lin, R. K., Huang, C. C., Chen, W. T. L., Ke, T. W. & Wei, P. L., Aug 1 2016, In : PLoS One. 11, 8, e0160550.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2017
7 Citations (Scopus)

Hypermethylation of BEND5 contributes to cell proliferation and is a prognostic marker of colorectal cancer

Lin, R. K., Hung, W. Y., Huang, Y. F., Chang, Y. J., Lin, C. H., Chen, W. Y., Chiu, S. F., Chang, S. C. & Tsai, S. F., Jan 1 2017, In : Oncotarget. 8, 69, p. 113431-113443 13 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
12 Citations (Scopus)

Prediction of novel target genes and pathways involved in irinotecan-resistant colorectal cancer

Makondi, P. T., Chu, C. M., Wei, P. L. & Chang, Y. J., Jul 1 2017, In : PLoS One. 12, 7, e0180616.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2018

A common regulatory variant in SLC35B4 influences the recurrence and survival of prostate cancer

Huang, E. Y., Chang, Y. J., Huang, S. P., Lin, V. C., Yu, C. C., Huang, C. Y., Yin, H. L., Chang, T. Y., Lu, T. L. & Bao, B. Y., Jul 1 2018, In : Journal of Cellular and Molecular Medicine. 22, 7, p. 3661-3670 10 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
1 Citation (Scopus)

Coupling dichloroacetate treatment with curcumin significantly enhances anticancer potential

Kan, P. C., Chang, Y. J., Chien, C. S., Su, C. Y. & Fang, H. W., Nov 1 2018, In : Anticancer Research. 38, 11, p. 6253-6261 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
5 Citations (Scopus)

Heat shock protein 27 influences the anti-cancer effect of curcumin in colon cancer cells through ROS production and autophagy activation

Liang, H. H., Huang, C. Y., Chou, C. W., Makondi, P. T., Huang, M. T., Wei, P. L. & Chang, Y. J., Sep 15 2018, In : Life Sciences. 209, p. 43-51 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Maspin enhances the anticancer activity of curcumin in hormone-refractory prostate cancer cells

Cheng, W. L., Huang, C. Y., Tai, C. J., Chang, Y. J. & Hung, C. S., Feb 1 2018, In : Anticancer Research. 38, 2, p. 863-870 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2 Citations (Scopus)

Prediction of novel target genes and pathways involved in bevacizumab-resistant colorectal cancer

Makondi, P. T., Lee, C. H., Huang, C. Y., Chu, C. M., Chang, Y. J. & Wei, P. L., Jan 1 2018, In : PLoS One. 13, 1, e0189582.

Research output: Contribution to journalArticle

3 Citations (Scopus)