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Personal profile

Education

  • 2003-2009 Ph.D., Department of Biochemistry, Duke University, USA
  • 1997-2001 B.S., Department of Physics, National Taiwan University

Experience

  • Assistant Professor, Department of Biochemistry and Molecular Cell Biology, Taipei Medical University
  • 2018.08- Assistant Professor, International Ph.D. Program for Cell Therapy and Regeneration Medicine, Taipei Medical University
  • 2016.03-2017.07 Assistant Professor, Ph.D. Program for Cancer Molecular Biology and drug Discovery, Taipei Medical University
  • 2015.08-2016.03 Assistant Researcher, Ph.D. Program for Cancer Molecular Biology and drug Discovery, Taipei Medical University

Fingerprint Dive into the research topics where Yu-Chu Chang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Ribonuclease P Medicine & Life Sciences
Protein folding Chemical Compounds
Protein Folding Medicine & Life Sciences
Bacilli Chemical Compounds
Bacillus subtilis Medicine & Life Sciences
Ligands Medicine & Life Sciences
Proteins Medicine & Life Sciences
Intrinsically Disordered Proteins Medicine & Life Sciences

Projects 2017 2020

建立探討膜蛋白折疊的研究平台(1/3)

Chang, Y.

8/1/197/1/20

Project: A - Government Institutionb - Ministry of Science and Technology

108大專生計畫獎-張語曲

Chang, Y.

8/1/197/1/20

Project: A - Government Institutionb - Ministry of Science and Technology

利用蛋白質交互作用探討沙門氏菌 YqiC蛋白質的功能

Chang, Y.

7/1/192/1/20

Project: A - Government Institutionb - Ministry of Science and Technology

張語曲-107研究計畫績效獎

Chang, Y.

8/1/187/31/20

Project: B - Project of TMUh - Other (Funded by TMU)

Research Output 2007 2014

  • 484 Citations
  • 7 h-Index
  • 7 Article
  • 1 Chapter
36 Citations (Scopus)

Ligand concentration regulates the pathways of coupled protein folding and binding

Daniels, K. G., Tonthat, N. K., McClure, D. R., Chang, Y. C., Liu, X., Schumacher, M. A., Fierke, C. A., Schmidler, S. C. & Oas, T. G., Jan 22 2014, In : Journal of the American Chemical Society. 136, 3, p. 822-825 4 p.

Research output: Contribution to journalArticle

Protein folding
Protein Folding
Protein Binding
Ligands
Proteins
52 Citations (Scopus)

Local anesthetics induce apoptosis in human breast tumor cells

Chang, Y. C., Liu, C. L., Chen, M. J., Hsu, Y. W., Chen, S. N., Lin, C. H., Chen, C. M., Yang, F. M. & Hu, M. C., Jan 1 2014, In : Anesthesia and Analgesia. 118, 1, p. 116-124 9 p.

Research output: Contribution to journalArticle

Local Anesthetics
Apoptosis
Breast Neoplasms
Caspase 7
Bupivacaine
29 Citations (Scopus)

Measuring membrane protein stability under native conditions

Chang, Y. C. & Bowie, J. U., 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 1, p. 219-224 6 p.

Research output: Contribution to journalArticle

Protein Stability
Thermodynamics
Bacteriorhodopsins
Membrane Proteins
Membranes
15 Citations (Scopus)

Measuring transmembrane helix interaction strengths in lipid bilayers using steric trapping

Hong, H., Chang, Y-C. & Bowie, J. U., 2013, Methods in Molecular Biology. Vol. 1063. p. 37-56 20 p. (Methods in Molecular Biology; vol. 1063).

Research output: Chapter in Book/Report/Conference proceedingChapter

Lipid Bilayers
Streptavidin
Competitive Binding
Biotin
Membrane Proteins
35 Citations (Scopus)

Osmolyte-induced folding of an intrinsically disordered protein: Folding mechanism in the absence of ligand

Chang, Y. C. & Oas, T. G., Jun 29 2010, In : Biochemistry. 49, 25, p. 5086-5096 11 p.

Research output: Contribution to journalArticle

Intrinsically Disordered Proteins
Protein folding
Protein Folding
Ligands
Proteins