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Yu-Chu Chang

Assistant Professor

 https://orcid.org/0000-0002-1751-8354
  • 453 Citations
  • 6 h-Index
20072019

Research output per year

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Personal profile

Education

  • 2003-2009 Ph.D., Department of Biochemistry, Duke University, USA
  • 1997-2001 B.S., Department of Physics, National Taiwan University

Experience

  • 2017.08- Assistant Professor, Department of Biochemistry and Molecular Cell Biology, Taipei Medical University
  • 2018.08- Assistant Professor, International Ph.D. Program for Cell Therapy and Regeneration Medicine, Taipei Medical University
  • 2016.03-2017.07 Assistant Professor, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, Taipei Medical University
  • 2015.08-2016.03 Assistant Researcher, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, Taipei Medical University
  • 2015.03-2015.08 Staff Research Associate, University of California, Los Angeles
  • 2010.03-2015.03 Postdoctoral Researcher, University of California, Los Angeles
  • 2009.06-2010.02 Postdoctoral Researcher, Duke University

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Projects

Effects of Lipid Composition on Membrane Protein Folding

Chang, Y.

8/1/19 → 7/31/20

Project: A - Government Institution › b - Ministry of Science and Technology

利用蛋白質交互作用探討沙門氏菌 YqiC蛋白質的功能

Chang, Y.

7/1/19 → 2/1/20

Project: A - Government Institution › b - Ministry of Science and Technology

發展迎戰抗生素抗藥性沙門氏桿菌的新策略-新發現沙門氏桿菌蛋白質YqiC之生物化學與生物物理學特性研究

Chang, Y.

1/1/19 → 12/1/19

Project: A - Government Institution › d - Ministry of Education

Thermodynamic Stability and Folding Kinetics of Membrane Proteins

Chang, Y.

8/1/18 → 9/1/19

Project: A - Government Institution › b - Ministry of Science and Technology

新聘教師研究補助

Chang, Y.

10/1/17 → 9/30/18

Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

Research Output

  • 453 Citations
  • 6 h-Index
  • 7 Article
  • 1 Chapter

ATP Synthase Subunit Epsilon Overexpression Promotes Metastasis by Modulating AMPK Signaling to Induce Epithelial-to-Mesenchymal Transition and Is a Poor Prognostic Marker in Colorectal Cancer Patients

Huang, Y-J., Jan, Y-H., Chang, Y-C., Tsai, H-F., Wu, A. T., Chen, C-L. & Hsiao, M., Jul 21 2019, In : Journal of Clinical Medicine. 8, 7

Research output: Contribution to journal › Article

    • Ligand concentration regulates the pathways of coupled protein folding and binding

    Daniels, K. G., Tonthat, N. K., McClure, D. R., Chang, Y. C., Liu, X., Schumacher, M. A., Fierke, C. A., Schmidler, S. C. & Oas, T. G., Jan 22 2014, In : Journal of the American Chemical Society. 136, 3, p. 822-825 4 p.

    Research output: Contribution to journal › Article

    • 41 Citations (Scopus)

    Measuring membrane protein stability under native conditions

    Chang, Y. C. & Bowie, J. U., 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 1, p. 219-224 6 p.

    Research output: Contribution to journal › Article

    • 31 Citations (Scopus)

    Measuring transmembrane helix interaction strengths in lipid bilayers using steric trapping

    Hong, H., Chang, Y-C. & Bowie, J. U., 2013, Methods in Molecular Biology. Vol. 1063. p. 37-56 20 p. (Methods in Molecular Biology; vol. 1063).

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

    • 15 Citations (Scopus)

    Osmolyte-induced folding of an intrinsically disordered protein: Folding mechanism in the absence of ligand

    Chang, Y. C. & Oas, T. G., Jun 29 2010, In : Biochemistry. 49, 25, p. 5086-5096 11 p.

    Research output: Contribution to journal › Article

    • 38 Citations (Scopus)