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Research Output 1995 2018

  • 5764 Citations
  • 40 h-Index
  • 125 Article
  • 3 Review article
2018
1 Citation (Scopus)

MCPIP3 as a potential metastasis suppressor gene in human colorectal cancer

Suk, F. M., Chang, C. C., Lin, R. J., Lin, S. Y., Chen, Y. T. & Liang, Y. C., May 3 2018, In : International Journal of Molecular Sciences. 19, 5, 1350.

Research output: Contribution to journalArticle

Monocyte Chemoattractant Proteins
monocytes
suppressors
metastasis
Tumor Suppressor Genes
3 Citations (Scopus)

MlcroRNA-124 inhibits proliferation and metastasis of esophageal cancer via negatively regulating NRP1

Zang, R. K., Ma, J. B., Liang, Y. C., Wang, Y., Hu, S. L., Zhang, Y., Dong, W., Zhang, W. & Hu, L. K., Jan 1 2018, In : European Review for Medical and Pharmacological Sciences. 22, 14, p. 4532-4541 10 p.

Research output: Contribution to journalReview article

Esophageal Neoplasms
MicroRNAs
Neoplasm Metastasis
Down-Regulation
Cell Movement
3 Citations (Scopus)

RBM4A-SRSF3-MAP4K4 splicing cascade constitutes a molecular mechanism for regulating brown adipogenesis

Peng, H. Y., Liang, Y. C., Tan, T. H., Chuang, H. C., Lin, Y. J. & Lin, J. C., Sep 6 2018, In : International Journal of Molecular Sciences. 19, 9, 2646.

Research output: Contribution to journalArticle

Brown Adipocytes
Adipogenesis
splicing
RNA
cascades
5 Citations (Scopus)

RBM4-SRSF3-MAP4K4 splicing cascade modulates the metastatic signature of colorectal cancer cell

Lin, J. C., Lee, Y. C., Tan, T. H., Liang, Y. C., Chuang, H. C., Fann, Y. C., Johnson, K. R. & Lin, Y. J., Feb 1 2018, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1865, 2, p. 259-272 14 p.

Research output: Contribution to journalArticle

RNA-Binding Proteins
Colorectal Neoplasms
Mitogen-Activated Protein Kinase 8
Cadherins
Alternative Splicing
4 Citations (Scopus)

ZFP36L1 and ZFP36L2 inhibit cell proliferation in a cyclin D-dependent and p53-independent manner

Suk, F-M., Chang, C-C., Lin, R-J., Lin, S-Y., Liu, S-C., Jau, C-F. & Liang, Y-C., Feb 9 2018, In : Scientific Reports. 8, 1, p. 2742

Research output: Contribution to journalArticle

Cyclin D
Cell Proliferation
Zinc Fingers
HCT116 Cells
Cyclin B
2017
3 Citations (Scopus)

The impact of the RBM4-initiated splicing cascade on modulating the carcinogenic signature of colorectal cancer cells

Lin, J. C., Lee, Y. C., Liang, Y. C., Fann, Y. C., Johnson, K. R. & Lin, Y. J., Mar 9 2017, In : Scientific Reports. 7, 44204.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Introns
Alternative Splicing
RNA
RNA Sequence Analysis
15 Citations (Scopus)

Valproic acid inhibits glioblastoma multiforme cell growth via paraoxonase 2 expression

Tseng, J. H., Chen, C. Y., Chen, P. C., Hsiao, S. H., Fan, C. C., Liang, Y. C. & Chen, C. P., 2017, In : Oncotarget. 8, 9, p. 14666-14679 14 p.

Research output: Contribution to journalArticle

Aryldialkylphosphatase
Valproic Acid
Glioblastoma
Growth
Reactive Oxygen Species

Vitis thunbergii var. Taiwaniana leaf extract reduces blood glucose levels in mice with streptozotocin-induced diabetes

Leung, W., Ho, F. M., Li, W. P. & Liang, Y. C., 2017, In : International Journal of Pharmacology. 13, 5, p. 457-464 8 p.

Research output: Contribution to journalArticle

Experimental Diabetes Mellitus
Vitis
Blood Glucose
Water
Streptozocin
2016
5 Citations (Scopus)

Glycine N-methyltransferase deficiency in female mice impairs insulin signaling and promotes gluconeogenesis by modulating the PI3K/Akt pathway in the liver

Liao, Y. J., Lee, T. S., Twu, Y. C., Hsu, S. M., Yang, C. P., Wang, C. K., Liang, Y. C. & Chen, Y-M., Oct 4 2016, In : Journal of Biomedical Science. 23, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

Glycine N-Methyltransferase
Gluconeogenesis
Phosphatidylinositol 3-Kinases
Liver
Insulin
8 Citations (Scopus)
Cysteine-Rich Protein 61
Epidermal Growth Factor
Cell Movement
Cyclic AMP Response Element-Binding Protein
Epithelial-Mesenchymal Transition
7 Citations (Scopus)

Niemann-Pick type C2 protein mediates hepatic stellate cells activation by regulating free cholesterol accumulation

Twu, Y. C., Lee, T. S., Lin, Y. L., Hsu, S. M., Wang, Y. H., Liao, C. Y., Wang, C. K., Liang, Y. C. & Liao, Y. J., Jul 13 2016, In : International Journal of Molecular Sciences. 17, 7, 1122.

Research output: Contribution to journalArticle

Hepatic Stellate Cells
Cholesterol
cholesterol
Chemical activation
activation
11 Citations (Scopus)

The probiotic activity of Lactobacillus murinus against food allergy

Huang, C. H., Shen, C. C., Liang, Y. C. & Jan, T. R., Aug 1 2016, In : Journal of Functional Foods. 25, p. 231-241 11 p.

Research output: Contribution to journalArticle

Lactobacillus murinus
food allergies
Food Hypersensitivity
Probiotics
Lactobacillus
2015
17 Citations (Scopus)
Salvia miltiorrhiza
ribose
adenosine diphosphate
Functional Food
leukemias
7 Citations (Scopus)

Bortezomib inhibits Burkitt's lymphoma cell proliferation by downregulating sumoylated hnRNP K and c-Myc expression

Suk, F. M., Lin, S. Y., Lin, R-J., Hsine, Y. H., Liao, Y. J., Fang, S. U. & Liang, Y. C., 2015, In : Oncotarget. 6, 28, p. 25988-26001 14 p.

Research output: Contribution to journalArticle

Heterogeneous-Nuclear Ribonucleoprotein K
Burkitt Lymphoma
Down-Regulation
Cell Proliferation
Molecular Weight
11 Citations (Scopus)
Macrophage Colony-Stimulating Factor
Extracellular Signal-Regulated MAP Kinases
Cytoplasmic and Nuclear Receptors
Osteogenesis
RANK Ligand
8 Citations (Scopus)
troglitazone
Cysteine-Rich Protein 61
lovastatin
Lovastatin
epidermal growth factor

Correction: Surface-enhanced Raman scattering on a silver film-modified Au nanoparticle-decorated SiO2 mask array

Chang, C. C., Chen, L. Y., Yang, K. H., Chen, Q. Y., Liang, Y. C., Lin, S. Y. & Liu, Y. C., Aug 12 2015, In : RSC Advances. 5, 86, p. 70501 1 p.

Research output: Contribution to journalArticle

Silver
Raman scattering
Masks
Nanoparticles
7 Citations (Scopus)

N-hydroxycinnamide derivatives of osthole ameliorate hyperglycemia through activation of AMPK and p38 MAPK

Lee, W. H., Wu, H. H., Huang, W. J., Li, Y. N., Lin, R-J., Lin, S. Y. & Liang, Y. C., Mar 1 2015, In : Molecules. 20, 3, p. 4516-4529 14 p.

Research output: Contribution to journalArticle

hyperglycemia
AMP-Activated Protein Kinases
p38 Mitogen-Activated Protein Kinases
glucose
Hyperglycemia
11 Citations (Scopus)

Niemann-Pick type C2 protein regulates liver cancer progression via modulating ERK1/2 pathway: Clinicopathological correlations and therapeutical implications

Liao, Y. J., Fang, C. C., Yen, C. H., Hsu, S. M., Wang, C. K., Huang, S. F., Liang, Y. C., Lin, Y. Y., Chu, Y. T. & Chen, Y. M. A., Sep 1 2015, In : International Journal of Cancer. 137, 6, p. 1341-1351 11 p.

Research output: Contribution to journalArticle

MAP Kinase Signaling System
Liver Neoplasms
Hepatocellular Carcinoma
Proteins
Cholesterol
2 Citations (Scopus)

Surface-enhanced Raman scattering on a silver film-modified Au nanoparticle-decorated SiO2 mask array

Chang, C. C., Chen, L. Y., Yang, K. H., Chen, Q. Y., Liang, Y. C., Lin, S. Y. & Liu, Y. C., Jul 23 2015, In : RSC Advances. 5, 81, p. 66096-66103 8 p.

Research output: Contribution to journalArticle

Silver
Raman scattering
Masks
Nanoparticles
Calcium
13 Citations (Scopus)
RNA-Binding Proteins
Polypyrimidine Tract-Binding Protein
Colorectal Neoplasms
Alternative Splicing
Carcinogenesis
2014
13 Citations (Scopus)

Enterovirus-71 virus-like particles induce the activation and maturation of human monocyte-derived dendritic cells through TLR4 signaling

Lin, Y. L., Hu, Y. C., Liang, C. C., Lin, S. Y., Liang, Y. C., Yuan, H. P. & Chiang, B. L., Oct 31 2014, In : PLoS One. 9, 10, e111496.

Research output: Contribution to journalArticle

Enterovirus
virus-like particles
dendritic cells
Viruses
Virion
28 Citations (Scopus)

MCPIP1 suppresses hepatitis C virus replication and negatively regulates virus-induced proinflammatory cytokine responses

Lin, R-J., Chu, J. S., Chien, H. L., Tseng, C. H., Ko, P. C., Mei, Y. Y., Tang, W. C., Kao, Y. T., Cheng, H. Y., Liang, Y. C. & Lin, S. Y., Oct 15 2014, In : Journal of Immunology. 193, 8, p. 4159-4168 10 p.

Research output: Contribution to journalArticle

Virus Replication
Hepacivirus
Cytokines
Viruses
Virus Diseases
11 Citations (Scopus)
Cell Movement
Transforming Growth Factors
Adenocarcinoma
Derivatives
Phosphorylation
2013
17 Citations (Scopus)

15,16-dihydrotanshinone i-induced apoptosis in human colorectal cancer cells: Involvement of ATF3

Suk, F. M., Jou, W. J., Lin, R-J., Lin, S. Y., Tzeng, F. Y. & Liang, Y. C., Aug 2013, In : Anticancer Research. 33, 8, p. 3225-3232 8 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Apoptosis
Activating Transcription Factor 3
Salvia miltiorrhiza
Medicinal Plants
2 Citations (Scopus)
Propolis
Hepatocellular Carcinoma
Apoptosis
Activating Transcription Factor 3
Eukaryotic Initiation Factor-2
10 Citations (Scopus)

Cytotoxicity of (-)-vitisin B in human leukemia cells

Wu, S. S., Chen, L. G., Lin, R-J., Lin, S. Y., Lo, Y. E. & Liang, Y. C., Jul 2013, In : Drug and Chemical Toxicology. 36, 3, p. 313-319 7 p.

Research output: Contribution to journalArticle

Resveratrol
Cell death
Cytotoxicity
Leukemia
Cell proliferation
9 Citations (Scopus)
Cytotoxicity
Colon
Adenocarcinoma
Derivatives
Phosphorylation
2012
8 Citations (Scopus)

Association Between Multiple Sclerosis and Erectile Dysfunction: A Nationwide Case-Control Study

Keller, J. J., Liang, Y. C. & Lin, H. C., Jul 2012, In : Journal of Sexual Medicine. 9, 7, p. 1753-1759 7 p.

Research output: Contribution to journalArticle

Erectile Dysfunction
Multiple Sclerosis
Case-Control Studies
National Health Programs
Taiwan
14 Citations (Scopus)

Association Between Viral Hepatitis and Erectile Dysfunction: A Population-Based Case-Control Analysis

Chung, S. D., Keller, J. J., Liang, Y. C. & Lin, H. C., May 2012, In : Journal of Sexual Medicine. 9, 5, p. 1295-1302 8 p.

Research output: Contribution to journalArticle

Erectile Dysfunction
Hepatitis
Population
Hepatitis C
Hepatitis B
12 Citations (Scopus)

Characterizations of chondrocyte attachment and proliferation on electrospun biodegradable scaffolds of PLLA and PBSA for use in cartilage tissue engineering

Wei, J. D., Tseng, H., Chen, E. T. H., Hung, C. H., Liang, Y-C., Sheu, M-T. & Chen, C-H., May 2012, In : Journal of Biomaterials Applications. 26, 8, p. 963-985 23 p.

Research output: Contribution to journalArticle

Cartilage
Lactic acid
Tissue engineering
Scaffolds
Lactic Acid
29 Citations (Scopus)
Cartilage
Scaffolds (biology)
Platelets
Fibrin
Tissue engineering
16 Citations (Scopus)

NBM-HD-1: A novel histone deacetylase inhibitor with anticancer activity

Huang, W. J., Liang, Y. C., Chuang, S. E., Chi, L. L., Lee, C. Y., Lin, C. W., Chen, A. L., Huang, J. S., Chiu, C. J., Lee, C. F., Huang, C. Y. & Chen, C. N., 2012, In : Evidence-based Complementary and Alternative Medicine. 2012, 781417.

Research output: Contribution to journalArticle

Histone Deacetylase Inhibitors
bcl-1 Genes
Gelsolin
Propolis
Cyclin B1
2011
20 Citations (Scopus)
Salvia miltiorrhiza
Prostate
Apoptosis
Carcinoma
Transcription Factor CHOP
6 Citations (Scopus)
Catechin
Free Radicals
Erythrocyte Deformability
Oxygen
Blood Viscosity
24 Citations (Scopus)

A novel phycobiliprotein alleviates allergic airway inflammation by modulating immune responses

Chang, C. J., Yang, Y. H., Liang, Y. C., Chiu, C. J., Chu, K. H., Chou, H. N. & Chiang, B. L., Jan 1 2011, In : American Journal of Respiratory and Critical Care Medicine. 183, 1, p. 15-25 11 p.

Research output: Contribution to journalArticle

Phycobiliproteins
Phycocyanin
Inflammation
Interleukin-12
Dendritic Cells
26 Citations (Scopus)

Lovastatin inhibits proliferation of anaplastic thyroid cancer cells through up-regulation of p27 by interfering with the Rho/ROCK-mediated pathway

Zhong, W-B., Hsu, S. P., Ho, P. Y., Liang, Y. C., Chang, T. C. & Lee, W. S., Dec 1 2011, In : Biochemical Pharmacology. 82, 11, p. 1663-1672 10 p.

Research output: Contribution to journalArticle

Lovastatin
Up-Regulation
Cells
Cyclin A2
Cyclin D3
34 Citations (Scopus)

Osthole enhances glucose uptake through activation of AMP-activated protein kinase in skeletal muscle cells

Lee, W. H., Lin, R-J., Lin, S. Y., Chen, Y. C., Lin, H. M. & Liang, Y. C., Dec 28 2011, In : Journal of Agricultural and Food Chemistry. 59, 24, p. 12874-12881 8 p.

Research output: Contribution to journalArticle

AMP-activated protein kinase
AMP-Activated Protein Kinases
myocytes
Muscle Cells
Muscle
2010
6 Citations (Scopus)
Colonic Neoplasms
Apoptosis
Cell Line
DNA
Cell Cycle Proteins
38 Citations (Scopus)

Caffeic acid phenethyl ester inhibits nuclear factor-κB and protein kinase B signalling pathways and induces caspase-3 expression in primary human CD4+ T cells

Wang, L. C., Chu, K. H., Liang, Y. C., Lin, Y. L. & Chiang, B. L., May 2010, In : Clinical and Experimental Immunology. 160, 2, p. 223-232 10 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-akt
Nuclear Proteins
Caspase 3
T-Lymphocytes
Propolis
9 Citations (Scopus)

Carbon monoxide induces cyclooxygenase-2 expression through MAPKs and PKG in phagocytes

Lin, L. C., Ho, F. M., Yen, S. J., Wu, P. Y., Hung, L. F., Huang, W. J. & Liang, Y. C., Dec 2010, In : International Immunopharmacology. 10, 12, p. 1520-1525 6 p.

Research output: Contribution to journalArticle

Cyclooxygenase 2
Carbon Monoxide
Phagocytes
Dinoprostone
Macrophages
2 Citations (Scopus)
Chondrosarcoma
Glucosamine
Interleukin-1
Matrix Metalloproteinases
Facilitative Glucose Transport Proteins
16 Citations (Scopus)

Neuroprotective activity of vitis thunbergii var. taiwaniana extracts in vitro and in vivo

Wang, C. K., Chen, L. G., Wen, C. L., Hou, W. C., Hung, L. F., Yen, S. J., Shen, Y. J., Lin, S. Y. & Liang, Y. C., Feb 1 2010, In : Journal of Medicinal Food. 13, 1, p. 170-178 9 p.

Research output: Contribution to journalArticle

Vitis
Hydrogen Peroxide
Ethanol
Kainic Acid
Nitric Oxide
5 Citations (Scopus)
sitosterols
smooth muscle
myocytes
Smooth Muscle Myocytes
Muscle
2009
15 Citations (Scopus)

15-Deoxy-Δ12,14-prostaglandin J2 inhibits fibrogenic response in human hepatoma cells

Suk, F. M., Chen, C. H., Lin, S. Y., Cheng, C. J., Yen, S. J., Hung, L. F., Liu, D. Z. & Liang, Y. C., May 22 2009, In : Toxicology Letters. 187, 1, p. 22-27 6 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Peroxisome Proliferator-Activated Receptors
Connective Tissue Growth Factor
Hepatocellular Carcinoma
Phosphorylation
23 Citations (Scopus)
JNK Mitogen-Activated Protein Kinases
Extracellular Signal-Regulated MAP Kinases
Endothelial cells
Cell Adhesion Molecules
mitogen-activated protein kinase
61 Citations (Scopus)

An immunomodulatory protein, Ling Zhi-8, induced activation and maturation of human monocyte-derived dendritic cells by the NF-κB and MAPK pathways

Lin, Y. L., Liang, Y. C., Tseng, Y. S., Huang, H. Y., Chou, S. Y., Hseu, R. S., Huang, C. T. & Chiang, B. L., Oct 2009, In : Journal of Leukocyte Biology. 86, 4, p. 877-889 13 p.

Research output: Contribution to journalArticle

Interleukin-10
Dendritic Cells
Monocytes
Interleukin-12
Reishi
3 Citations (Scopus)
terbinafine
JNK Mitogen-Activated Protein Kinases
Endothelial cells
Umbilicus
Up-Regulation
41 Citations (Scopus)
Cell proliferation
Glioblastoma
cell proliferation
Up-Regulation
Cell Proliferation
76 Citations (Scopus)

Osthole, a potential antidiabetic agent, alleviates hyperglycemia in db/db mice

Liang, H. J., Suk, F. M., Wang, C. K., Hung, L. F., Liu, D. Z., Chen, N. Q., Chen, Y. C., Chang, C. C. & Liang, Y. C., Oct 30 2009, In : Chemico-Biological Interactions. 181, 3, p. 309-315 7 p.

Research output: Contribution to journalArticle

Hypoglycemic Agents
Peroxisome Proliferator-Activated Receptors
Hyperglycemia
Cnidium
Assays