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Research Output 2005 2019

  • 1047 Citations
  • 17 h-Index
  • 25 Article
2019
2 Citations (Scopus)

Prognostic signature associated with radioresistance in head and neck cancer via transcriptomic and bioinformatic analyses

You, G. R., Cheng, A. J., Lee, L. Y., Huang, Y. C., Liu, H., Chen, Y. J. & Chang, J. T., Jan 14 2019, In : BMC Cancer. 19, 1, 64.

Research output: Contribution to journalArticle

Open Access
Head and Neck Neoplasms
Computational Biology
Atlases
Radiotherapy
Genome
2018
7 Citations (Scopus)

Annexin A2-mediated cancer progression and therapeutic resistance in nasopharyngeal carcinoma

Chen, C. Y., Lin, Y. S., Chen, C. H. & Chen, Y. J., Mar 29 2018, In : Journal of Biomedical Science. 25, 1, 30.

Research output: Contribution to journalArticle

Annexin A2
Annexins
Chemoradiotherapy
Neoplasms
Chemotherapy

IONIZING RADIATION-INDUCED CANCER STEMNESS GENE EXPRESSI ON IS REGULATED BY MATRI X NANOTOPOGRAPHY

Lu, L-S., Chen, Y-J., Lin, Y-T., Lee, J-T. & Chiou, J-F., 2018, In : 放射治療與腫瘤學. 25, 1, p. 13-20 8 p.

Research output: Contribution to journalArticle

Radiation-Induced Neoplasms
Neoplasm Genes
Ionizing Radiation
Cell Line
Neoplasms
3 Citations (Scopus)

Piperlongumine inhibits cancer stem cell properties and regulates multiple malignant phenotypes in oral cancer

Chen, Y. J., Kuo, C. C., Ting, L. L., Lu, L. S., Lu, Y. C., Cheng, A. J., Lin, Y. T., Chen, C. H., Tsai, J. T. & Chiou, J. F., Feb 1 2018, In : Oncology Letters. 15, 2, p. 1789-1798 10 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Mouth Neoplasms
Phenotype
Homeobox Genes
Radiation Tolerance
2016
2 Citations (Scopus)

Cisplatin-induced regulation of signal transduction pathways and transcription factors in p53-mutated subclone variants of hepatoma cells: Potential application for therapeutic targeting

Kuo, J. R., Shang, H. S., Ho, C. T., Lai, K. G., Liu, T. Z., Chen, Y-J. & Chiou, J-F., 2016, In : Oncology Letters. 12, 5, p. 3723-3730 8 p.

Research output: Contribution to journalArticle

2015
36 Citations (Scopus)

Combined determination of circulating miR-196a and miR-196b levels produces high sensitivity and specificity for early detection of oral cancer

Lu, Y. C., Chang, J. T. C., Huang, Y. C., Huang, C. C., Chen, W. H., Lee, L. Y., Huang, B. S., Chen, Y. J., Li, H. F. & Cheng, A. J., Feb 1 2015, In : Clinical Biochemistry. 48, 3, p. 115-121 7 p.

Research output: Contribution to journalArticle

Mouth Neoplasms
MicroRNAs
Early Detection of Cancer
Sensitivity and Specificity
Plasmas
7 Citations (Scopus)

Fascin is a circulating tumor marker for head and neck cancer as determined by a proteomic analysis of interstitial fluid from the tumor microenvironment

Chang, J. T. C., Lee, L. Y., Chen, Y. J., Lu, Y. C., Liao, C. T., Chen, I. H., Huang, Y. C., Chen, W. H., Huang, C. C., Tsai, C. Y. & Cheng, A. J., Sep 1 2015, In : Clinical Chemistry and Laboratory Medicine. 53, 10, p. 1631-1641 11 p.

Research output: Contribution to journalArticle

Tumor Microenvironment
Extracellular Fluid
Tumor Biomarkers
Head and Neck Neoplasms
Proteomics
22 Citations (Scopus)

Targeting annexin A2 reduces tumorigenesis and therapeutic resistance of nasopharyngeal carcinoma

Chen, C. Y., Lin, Y-S., Chen, C. L., Chao, P. Z., Chiou, J. F., Kuo, C. C., Lee, F. P., Lin, Y. F., Sung, Y. H., Lin, Y. T., Li, C. F., Chen, Y. J. & Chen, C. H., 2015, In : Oncotarget. 6, 29, p. 26946-26959 14 p.

Research output: Contribution to journalArticle

Annexin A2
Annexins
Carcinogenesis
Therapeutics
Cell Proliferation
2013
35 Citations (Scopus)

DSG3 Facilitates Cancer Cell Growth and Invasion through the DSG3-Plakoglobin-TCF/LEF-Myc/Cyclin D1/MMP Signaling Pathway

Chen, Y. J., Lee, L. Y., Chao, Y. K., Chang, J. T., Lu, Y. C., Li, H. F., Chiu, C. C., Li, Y. C., Li, Y. L., Chiou, J. F. & Cheng, A. J., May 30 2013, In : PLoS One. 8, 5, e64088.

Research output: Contribution to journalArticle

Desmoglein 3
gamma Catenin
cell invasion
Cyclin D1
cyclins
36 Citations (Scopus)

Epigenetic regulation of the X-linked tumour suppressors BEX1 and LDOC1 in oral squamous cell carcinoma

Lee, C. H., Wong, T. S., Chan, J. Y. W., Lu, S. C., Lin, P., Cheng, A. J., Chen, Y. J., Chang, J. S. M., Hsiao, S. H., Leu, Y. W., Li, C. I., Hsiao, J. R. & Chang, J. Y., Jul 2013, In : Journal of Pathology. 230, 3, p. 298-309 12 p.

Research output: Contribution to journalArticle

Epigenomics
Squamous Cell Carcinoma
Neoplasms
Methylation
High-Throughput Screening Assays
26 Citations (Scopus)

Grp78 as a therapeutic target for refractory head-neck cancer with CD24- CD44+ stemness phenotype

Chiu, C. C., Lee, L. Y., Li, Y. C., Chen, Y. J., Lu, Y. C., Li, Y. L., Wang, H. M., Chang, J. T. & Cheng, A. J., Nov 2013, In : Cancer Gene Therapy. 20, 11, p. 606-615 10 p.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Phenotype
Neoplastic Stem Cells
Therapeutics
Neoplasms
2012
17 Citations (Scopus)

Association of HPV infections with second primary tumors in early-staged oral cavity cancer

Huang, S. F., Li, H. F., Liao, C. T., Wang, H. M., Chen, I. H., Chang, J. T. C., Chen, Y. J. & Cheng, A. J., Nov 2012, In : Oral Diseases. 18, 8, p. 809-815 7 p.

Research output: Contribution to journalArticle

Papillomaviridae
Mouth Neoplasms
Virus Diseases
Mouth
Neoplasms
103 Citations (Scopus)

Oncogenic function and early detection potential of miRNA-10b in oral cancer as identified by microRNA profiling

Lu, Y. C., Chen, Y. J., Wang, H. M., Tsai, C. Y., Chen, W. H., Huang, Y. C., Fan, K. H., Tsai, C. N., Huang, S. F., Kang, C. J., Chang, J. T. C. & Cheng, A. J., Apr 2012, In : Cancer Prevention Research. 5, 4, p. 665-674 10 p.

Research output: Contribution to journalArticle

Mouth Neoplasms
MicroRNAs
Area Under Curve
Cell Movement
Cell Line
2011
91 Citations (Scopus)

A novel molecular signature identified by systems genetics approach predicts prognosis in oral squamous cell carcinoma

Peng, C. H., Liao, C. T., Peng, S. C., Chen, Y. J., Cheng, A. J., Juang, J. L., Tsai, C. Y., Chen, T. C., Chuang, Y. J., Tang, C. Y., Hsieh, W. P. & Yen, T. C., 2011, In : PLoS One. 6, 8, e23452.

Research output: Contribution to journalArticle

squamous cell carcinoma
prognosis
Mouth
Squamous Cell Carcinoma
mouth
19 Citations (Scopus)

Downregulation of Ches1 and other novel genes in oral cancer cells chronically exposed to areca nut extract

Chen, Y. J., Liao, C. T., Chen, P. J., Lee, L. Y., Li, Y. C., Chen, I. H., Wang, H. M., Chang, J. T., Chen, L. J., Yen, T. C., Tang, C. Y. & Cheng, A. J., Feb 2011, In : Head and Neck. 33, 2, p. 257-266 10 p.

Research output: Contribution to journalArticle

Areca
Nuts
Mouth Neoplasms
Down-Regulation
Genes
15 Citations (Scopus)

GP96 is over-expressed in oral cavity cancer and is a poor prognostic indicator for patients receiving radiotherapy

Lin, C. Y., Lin, T. Y., Wang, H. M., Huang, S. F., Fan, K. H., Liao, C. T., Chen, I. H., Lee, L. Y., Li, Y. L., Chen, Y. J., Cheng, A. J. & Chang, J. T., Oct 12 2011, In : Radiation Oncology. 6, 1, 136.

Research output: Contribution to journalArticle

Mouth Neoplasms
Mouth
Radiotherapy
Survival
Neoplasms
41 Citations (Scopus)

Molecular chaperones as a common set of proteins that regulate the invasion phenotype of head and neck cancer

Chiu, C. C., Lin, C. Y., Lee, L. Y., Chen, Y. J., Lu, Y. C., Wang, H. M., Liao, C. T., Chang, J. T. C. & Cheng, A. J., Jul 15 2011, In : Clinical Cancer Research. 17, 14, p. 4629-4641 13 p.

Research output: Contribution to journalArticle

Molecular Chaperones
Head and Neck Neoplasms
Glucosidases
Phenotype
Proteomics
2010
48 Citations (Scopus)

Highly potent and specific siRNAs against E6 or E7 genes of HPV16-or HPV18-infected cervical cancers

Chang, J. T. C., Kuo, T. F., Chen, Y. J., Chiu, C. C., Lu, Y. C., Li, H. F., Shen, C. R. & Cheng, A. J., Dec 2010, In : Cancer Gene Therapy. 17, 12, p. 827-836 10 p.

Research output: Contribution to journalArticle

Uterine Cervical Neoplasms
Human papillomavirus 18
Human papillomavirus 16
Genes
Apoptosis
2009
13 Citations (Scopus)

Transcriptome profiling and network pathway analysis of genes associated with invasive phenotype in oral cancer

Kang, C. J., Chen, Y. J., Liao, C. T., Wang, H. M., Chang, J. T., Lin, C. Y., Lee, L. Y., Wang, T. H., Yen, T. C., Shen, C. R., Chen, I. H., Chiu, C. C. & Cheng, A. J., Nov 1 2009, In : Cancer Letters. 284, 2, p. 131-140 10 p.

Research output: Contribution to journalArticle

Mouth Neoplasms
Gene Expression Profiling
Phenotype
Genes
Gene Knockdown Techniques
2008
45 Citations (Scopus)

Glucose-regulated protein 78 regulates multiple malignant phenotypes in head and neck cancer and may serve as a molecular target of therapeutic intervention

Chiu, C. C., Lin, C. Y., Lee, L. Y., Chen, Y. J., Kuo, T. F., Chang, J. T. C., Liao, C. T., Wang, H. M., Yen, T. C., Shen, C. R., Liao, S. K. & Cheng, A. J., 2008, In : Molecular Cancer Therapeutics. 7, 9, p. 2788-2797 10 p.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Phenotype
Cell Line
Growth
Heterografts
207 Citations (Scopus)

Head and neck cancer in the betel quid chewing area: Recent advances in molecular carcinogenesis

Chen, Y. J., Chang, J. T. C., Liao, C. T., Wang, H. M., Yen, T. C., Chiu, C. C., Lu, Y. C., Li, H. F. & Cheng, A. J., 2008, In : Cancer Science. 99, 8, p. 1507-1514 8 p.

Research output: Contribution to journalArticle

Mastication
Head and Neck Neoplasms
Carcinogenesis
Environmental Carcinogens
Neoplasms
2007
74 Citations (Scopus)

DSG3 is overexpressed in head neck cancer and is a potential molecular target for inhibition of oncogenesis

Chen, Y. J., Chang, J. T., Lee, L., Wang, H. M., Liao, C. T., Chiu, C. C., Chen, P. J. & Cheng, A. J., Jan 18 2007, In : Oncogene. 26, 3, p. 467-476 10 p.

Research output: Contribution to journalArticle

Desmoglein 3
Head and Neck Neoplasms
Carcinogenesis
RNA Interference
Cell Migration Assays
2006
45 Citations (Scopus)

hTERT phosphorylation by PKC is essential for telomerase holoprotein integrity and enzyme activity in head neck cancer cells

Chang, J. T., Lu, Y. C., Chen, Y. J., Tseng, C. P., Chen, Y. L., Fang, C. W. & Cheng, A. J., Mar 27 2006, In : British Journal of Cancer. 94, 6, p. 870-878 9 p.

Research output: Contribution to journalArticle

Telomerase
Head and Neck Neoplasms
Protein Kinase C
Phosphorylation
Enzymes
27 Citations (Scopus)

Increase diagnostic efficacy by combined use of fingerprint markers in mass spectrometry-Plasma peptidomes from nasopharyngeal cancer patients for example

Chang, J. T. C., Chen, L. C., Wei, S. Y., Chen, Y. J., Wang, H. M., Liao, C. T., Chen, I. H. & Cheng, A. J., Dec 2006, In : Clinical Biochemistry. 39, 12, p. 1144-1151 8 p.

Research output: Contribution to journalArticle

Nasopharyngeal Neoplasms
Dermatoglyphics
Mass spectrometry
Mass Spectrometry
Plasmas
2005
126 Citations (Scopus)

Oral cancer plasma tumor marker identified with bead-based affinity-fractionated proteomic technology

Cheng, A. J., Chen, L. C., Chien, K. Y., Chen, Y. J., Chang, J. T. C., Wang, H. M., Liao, C. T. & Chen, I. H., Dec 2005, In : Clinical Chemistry. 51, 12, p. 2236-2244 9 p.

Research output: Contribution to journalArticle

Mouth Neoplasms
Tumor Biomarkers
Proteomics
Technology
Plasmas