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Research Output

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Article
2020

Expression, purification, and characterization of anti-Zika virus envelope protein: Polyclonal and chicken-derived single chain variable fragment antibodies

Mwale, P. F., Lee, C. H., Lin, L. T., Leu, S. J., Huang, Y. J., Chiang, L. C., Mao, Y. C. & Yang, Y. Y., Jan 13 2020, In : International Journal of Molecular Sciences. 21, 2, 492.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
2019
2018

Characterization of chicken-derived single chain antibody fragments against venom of Naja naja atra

Lee, C. H., Leu, S. J., Lee, Y. C., Liu, C. I., Lin, L. T., Mwale, P. F., Chiang, J. R., Tsai, B. Y., Chen, C. C., Hung, C. S. & Yang, Y. Y., Oct 1 2018, In : Toxins. 10, 10, 383.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Comparison of Two Molecular Methods for Rapid Diagnosis of Tuberculosis

Lee, J. C., Wang, C-H., Liang, Y-L., Tsao, S., Liao, C-C., Yu, F-L., Hung, C-S., Yang, Y-Y. & Wang, G-C., 2018, In : Journal of Biomedical & Laboratory Sciences. 30, 1, p. 14-23 10 p.

Research output: Contribution to journalArticle

2017

Single chain antibody fragment against venom from the snake Daboia russelii formosensis

Lee, C. H., Lee, Y. C., Lee, Y. L., Leu, S. J., Lin, L. T., Chen, C. C., Chiang, J. R., Fellow, P., Tsai, B. Y., Hung, C. S. & Yang, Y. Y., Nov 1 2017, In : Toxins. 9, 11, 347.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Valproic Acid and Lithium Meditate Anti-Inflammatory Effects by Differentially Modulating Dendritic Cell Differentiation and Function

Leu, S. J., Yang, Y. Y., Liu, H. C., Cheng, C. Y., Wu, Y. C., Huang, M. C., Lee, Y. L., Chen, C. C., Shen, W. W. & Liu, K. J., May 1 2017, In : Journal of Cellular Physiology. 232, 5, p. 1176-1186 11 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2016

Antibodies against venom of the snake Deinagkistrodon acutus

Lee, C. H., Lee, Y. C., Liang, M. H., Leu, S. J., Lin, L. T., Chiang, J. R. & Yang, Y. Y., 2016, In : Applied and Environmental Microbiology. 82, 1, p. 71-80 10 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Evaluation of a modified direct agar proportion method for testing susceptibility of Mycobacterium tuberculosis from MGIT samples

Yu, F. L., Lee, J. C., Wang, M. S., Hsu, H. L., Chen, T. T., Cheng, C. L., Yang, Y. Y., Wang, G. C. & Yu, M. C., Feb 1 2016, In : Journal of Microbiology, Immunology and Infection. 49, 1, p. 60-65 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

From the fluorescent lamp-induced bactericidal performance of sputtered Ag/TiO2 films to re-explore the photocatalytic mechanism

Kuo, D. H., Hsu, W. T. & Yang, Y. Y., May 5 2016, In : Applied Catalysis B: Environmental. 184, p. 191-200 10 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Production and characterization of neutralizing antibodies against Bungarus multicinctus snake venom

Lee, C. H., Lee, Y-C., Leu, S-J., Lin, L-T., Chiang, J. R., Hsu, W. J. & Yang, Y-Y., 2016, In : Applied and Environmental Microbiology. 82, 23, p. 6973-6982 10 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Recombinant OmpA protein fragments mediate interleukin-17 regulation to prevent Escherichia coli meningitis

Hsieh, W. S., Yang, Y. Y., Lin, P. H., Chang, C. C. & Wu, H. H., Dec 1 2016, In : Journal of Microbiology, Immunology and Infection. 49, 6

Research output: Contribution to journalArticle

2 Citations (Scopus)

Recombinant outer membrane protein A fragments protect against Escherichia coli meningitis

Hsieh, W. S., Yang, Y. Y., Yang, H. Y., Huang, Y. S. & Wu, H. H., Jun 1 2016, In : Journal of Microbiology, Immunology and Infection. 49, 3, p. 329-334

Research output: Contribution to journalArticle

4 Citations (Scopus)
2015

Anti-a-enolase is a prognostic marker in postoperative lung cancer patients

Hsiao, K. C., Shih, N. Y., Chu, P. Y., Hung, Y. M., Liao, J. Y., Chou, S. W., Yang, Y. Y., Chang, G. C. & Liu, K. J., 2015, In : Oncotarget. 6, 33, p. 35073-35086 14 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Single chain antibody fragment with serine protease inhibitory property capable of neutralizing toxicity of Trimeresurus mucrosquamatus venom

Lee, Y. C., Chen, W. C., Liang, M. H., Lee, C. H., Tsai, K. C., Chiang, J. R., Chiang, L. C., Chen, C. C., Chang, C. Y., Lee, C. H., Leu, S. J. & Yang, Y. Y., May 1 2015, In : Biochemical and Biophysical Research Communications. 460, 2, p. 170-176 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2013
4 Citations (Scopus)

Surface α-Enolase Promotes Extracellular Matrix Degradation and Tumor Metastasis and Represents a New Therapeutic Target

Hsiao, K. C., Shih, N. Y., Fang, H. L., Huang, T. S., Kuo, C. C., Chu, P. Y., Hung, Y. M., Chou, S. W., Yang, Y. Y., Chang, G. C. & Liu, K. J., Jul 19 2013, In : PLoS One. 8, 7, e69354.

Research output: Contribution to journalArticle

63 Citations (Scopus)
15 Citations (Scopus)
2012

A real time detection of the ovarian tumor associated antigen 1 (OVTA 1) in human serum by quartz crystal microbalance immobilized with anti-OVTA 1 polyclonal chicken IgY antibodies

Sadhasivam, S., Chen, J. C., Savitha, S., Lin, F. H., Yang, Y. Y. & Lee, C. H., Oct 1 2012, In : Materials Science and Engineering C. 32, 7, p. 2073-2078 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2011

Carbon tetrachloride-induced hepatotoxicity and its amelioration by Agaricus blazei Murrill extract in a mouse model

Chang, J. B., Wu, M. F., Yang, Y. Y., Leu, S. J., Chen, Y. L., Yu, C. S., Yu, C. C., Chang, S. J., Lu, H. F. & Chung, J. G., Nov 2011, In : In Vivo. 25, 6, p. 971-976 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Evaluation of genotoxicity of Antrodia cinnamomea in the Ames test and the in vitro chromosomal aberration test

Wu, M. F., Peng, F. C., Chen, Y. L., Lee, C. S., Yang, Y. Y., Yeh, M. Y., Liu, C. M., Chang, J. B., Wu, R. S. C., Yu, C. C., Lu, H. F. & Chung, J. G., May 2011, In : In Vivo. 25, 3, p. 419-423 5 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Identification of salt-inducible kinase 3 as a novel tumor antigen associated with tumorigenesis of ovarian cancer

Charoenfuprasert, S., Yang, Y. Y., Lee, Y. C., Chao, K. C., Chu, P. Y., Lai, C. R., Hsu, K. F., Chang, K. C., Chen, Y. C., Chen, L. T., Chang, J. Y., Leu, S. J. & Shih, N. Y., Aug 18 2011, In : Oncogene. 30, 33, p. 3570-3584 15 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Modulation of the development of human monocyte-derived dendritic cells by lithium chloride

Liu, K. J., Lee, Y. L., Yang, Y. Y., Shih, N. Y., Ho, C. C., Wu, Y. C., Huang, T. S., Huang, M. C., Liu, H. C., Shen, W. W. & Leu, S. J., Feb 2011, In : Journal of Cellular Physiology. 226, 2, p. 424-433 10 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Nicotine-induced human breast cancer cell proliferation attenuated by garcinol through down-regulation of the nicotinic receptor and cyclin D3 proteins

Chen, C. S., Lee, C-H., Hsieh, C. D., Ho, C. T., Pan, M. H., Huang, C. S., Tu, S-H., Wang, Y. J., Chen, L-C., Chang, Y-J., Wei, P-L., Yang, Y-Y., Wu, C-H. & Ho, Y-S., Jan 2011, In : Breast Cancer Research and Treatment. 125, 1, p. 73-87 15 p.

Research output: Contribution to journalArticle

83 Citations (Scopus)

Possible reduction of hepatoma formation by Smmu 7721 cells in SCID mice and metastasis formation by B16F10 melanoma cells in C57BL/6 mice by Agaricus blazei murill extract

Wu, M. F., Lu, H. F., Hsu, Y. M., Tang, M. C., Chen, H. C., Lee, C. S., Yang, Y. Y., Yeh, M. Y., Chung, H. K., Huang, Y. P., Wu, C. C. & Chung, J. G., May 2011, In : In Vivo. 25, 3, p. 399-404 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2010

Antitumor activity of capsaicin on human colon cancer cells in vitro and colo 205 tumor xenografts in vivo

Lu, H. F., Chen, Y. L., Yang, J. S., Yang, Y. Y., Liu, J. Y., Hsu, S. C., Lai, K. C. & Chung, J. G., Dec 22 2010, In : Journal of Agricultural and Food Chemistry. 58, 24, p. 12999-13005 7 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)

Combination treatment with luteolin and quercetin enhances antiproliferative effects in nicotine-treated MDA-MB-231 cells by down-regulating nicotinic acetylcholine receptors

Shih, Y. L., Liu, H. C., Chen, C. S., Hsu, C-H., Pan, M. H., Chang, H. W., Chang, C. H., Chen, F. C., Ho, C. T., Yang, Y-Y. & Ho, Y-S., Jan 13 2010, In : Journal of Agricultural and Food Chemistry. 58, 1, p. 235-241 7 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

Generation and characterization of anti-α-enolase single-chain antibodies in chicken

Leu, S. J., Lee, Y. C., Shih, N. Y., Huang, I. J., Liu, K. J., Lu, H. F., Huang, S. Y. & Yang, Y. Y., Oct 2010, In : Veterinary Immunology and Immunopathology. 137, 3-4, p. 251-260 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Knockdown of thrombomodulin enhances HCC cell migration through increase of ZEB1 and decrease of E-cadherin gene expression

Huang, M. T., Wei, P. L., Liu, J. J., Liu, D. Z., Huang, H. C., An, J., Wu, C. C., Wu, C. H., Ho, Y. S., Yang, Y. Y. & Chang, Y. J., Dec 2010, In : Annals of Surgical Oncology. 17, 12, p. 3379-3385 7 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Nonmuscle myosin IIA (myosin heavy polypeptide 9): A novel class of signal transducer mediating the activation of Gαh/phospholipase C-δ1 pathway

Lin, Y. F., Yeh, T. S., Chen, S. F., Tsai, Y. H., Chou, C. M., Yang, Y. Y. & Huang, H. M., Mar 2010, In : Endocrinology. 151, 3, p. 876-885 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2009

OmpA is the critical component for escherichia coli invasion-induced astrocyte activation

Wu, H. H., Yang, Y. Y., Hsieh, W. S., Lee, C. H., Leu, S. J. C. & Chen, M. R., Jun 2009, In : Journal of Neuropathology and Experimental Neurology. 68, 6, p. 677-690 14 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Reduction of monocyte chemoattractant protein-1 and interleukin-8 levels by ticlopidine in TNF-α stimulated human umbilical vein endothelial cells

Hu, C. J., Lee, Y. L., Shih, N. Y., Yang, Y. Y., Charoenfuprasert, S., Dai, Y. S., Chang, S. M., Tsai, Y-H., Tseng, H., Liu, C. Y. & Leu, S. J., 2009, In : Journal of Biomedicine and Biotechnology. 2009, 917837.

Research output: Contribution to journalArticle

8 Citations (Scopus)
98 Citations (Scopus)
62 Citations (Scopus)
2008

The effect of Chinese herbal medicines on TNF-α induced matrix metalloproteinase-1, -9 activities and interleukin-8 secretion

Lee, M. H., Yang, Y. Y., Tsai, Y-H., Lee, Y. L., Huang, P. Y., Huang, I. J., Cheng, K. T. & Leu, S. J., Oct 2008, In : Botanical Studies. 49, 4, p. 301-309 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2007

(-)-Menthol inhibits WEHI-3 leukemia cells in vitro and in vivo

Lu, H. F., Liu, J. Y., Hsueh, S. C., Yang, Y. Y., Yang, J. S., Tan, T. W., Kok, L. F., Lu, C. C., Lan, S. H., Wu, S. Y., Liao, S. S., Ip, S. W. & Chung, J. G., Mar 2007, In : In Vivo. 21, 2, p. 285-289 5 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

A dominant antigenic epitope on SARS-CoV spike protein identified by an avian single-chain variable fragment (scFv)-expressing phage

Lee, Y. C., Leu, S. J. C., Hung, H. C., Wu, H. H., Huang, I. J., Hsieh, W. S., Chiu, W. T., Hsieh, M. S., Cheng, T. F. & Yang, Y. Y., May 15 2007, In : Veterinary Immunology and Immunopathology. 117, 1-2, p. 75-85 11 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Carotenoids suppress proliferating cell nuclear antigen and cyclin D1 expression in oral carcinogenic models

Cheng, H. C., Chien, H., Liao, C. H., Yang, Y. Y. & Huang, S. Y., Oct 2007, In : Journal of Nutritional Biochemistry. 18, 10, p. 667-675 9 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Characterization of novel transforming growth factor-beta type I receptors found in malignant pleural effusion tumor cells

Chen, K. L., Liu, W. H., Yang, Y. Y., Leu, S. J. C. & Shih, N. Y., Aug 17 2007, In : BMC Molecular Biology. 8, 72.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Chicken single-chain variable fragments against the SARS-CoV spike protein

Lee, Y. C., Leu, S. J. C., Hu, C. J., Shih, N. Y., Huang, I. J., Wu, H. H., Hsieh, W. S., Chiang, B. L., Chiu, W. T. & Yang, Y. Y., Dec 2007, In : Journal of Virological Methods. 146, 1-2, p. 104-111 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2006

Anti-heat shock protein 90 is increased in acute mania

Shen, W. W., Liu, H. C., Yang, Y. Y., Lin, C. Y., Chen, K. P., Tsai, T-S. & Leu, S. J., Aug 2006, In : Australian and New Zealand Journal of Psychiatry. 40, 8, p. 712-716 5 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
10 Citations (Scopus)
2005

Infrared thermography to mass-screen suspected sars patients with fever

Chiu, W. T., Lin, P. W., Chiou, H. Y., Lee, W. S., Lee, C. N., Yang, Y. Y., Lee, H. M., Hsieh, M. S., Hu, C. J., Ho, Y. S., Deng, W. P. & Hsu, C. Y., 2005, In : Asia-Pacific Journal of Public Health. 17, 1, p. 26-28 3 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)
2004

Aspirin inhibits monocyte chemoattractant protein-1 and interleukin-8 expression in TNF-α stimulated human umbilical vein endothelial cells

Yang, Y. Y., Hu, C. J., Chang, S. M., Tai, T. Y. & Leu, S. J., Jun 2004, In : Atherosclerosis. 174, 2, p. 207-213 7 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)

Immunologic variables in acute mania of bipolar disorder

Liu, H. C., Yang, Y. Y., Chou, Y. M., Chen, K. P., Shen, W. W. & Leu, S. J., May 2004, In : Journal of Neuroimmunology. 150, 1-2, p. 116-122 7 p.

Research output: Contribution to journalArticle

104 Citations (Scopus)
2003

Detection and investigation of TT virus infection in Taiwanese population

Chiu, Y-Y., Yeung, C. Y., Leu, S-J., Hsieh, W. S., Hsieh, M-S. & Yang, Y-Y., 2003, In : J. Biomedical and Laboratory Sciences. 15, p. 27-34 8 p.

Research output: Contribution to journalArticle

2002

Contribution of heavy chain genes on the binding property of a recombinant human IgG rheumatoid factor

Lee, Y-C., Leu, S-J., Hsieh, M-S., Huang, I. J. & Yang, Y-Y., 2002, In : J. Biomedical and Laboratory Sciences. 14, p. 89-94 6 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)
2001

Effects of symptomatic severity on elevation of plasma soluble interleukin-2 receptor in bipolar mania

Tsai, S. Y. M., Yang, Y. Y., Kuo, C. J., Chen, C. C. & Leu, S. J. C., 2001, In : Journal of Affective Disorders. 64, 2-3, p. 185-193 9 p.

Research output: Contribution to journalArticle

86 Citations (Scopus)
1999

Activation of indices of cell-mediated immunity in bipolar mania

Tsai, S. Y., Chen, K. P., Yang, Y. Y., Chen, C. C., Lee, J. C., Singh, V. K. & Leu, S. J. C., Apr 15 1999, In : Biological Psychiatry. 45, 8, p. 989-994 6 p.

Research output: Contribution to journalArticle

99 Citations (Scopus)