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Research Output 1989 2019

  • 1424 Citations
  • 20 h-Index
  • 65 Article
2019
Single-Chain Antibodies
Epitopes
Escherichia coli
Amino Acids
OMPA outer membrane proteins
2018
1 Citation (Scopus)

Characterization of chicken-derived single chain antibody fragments against venom of Naja naja atra

Lee, C. H., Leu, S. J., Lee, Y. C., Liu, C. I., Lin, L. T., Mwale, P. F., Chiang, J. R., Tsai, B. Y., Chen, C. C., Hung, C. S. & Yang, Y. Y., Oct 1 2018, In : Toxins. 10, 10, 383.

Research output: Contribution to journalArticle

Cobra Venoms
Elapidae
Single-Chain Antibodies
Immunoglobulin Fragments
Venoms

Comparison of Two Molecular Methods for Rapid Diagnosis of Tuberculosis

Lee, J. C., Wang, C-H., Liang, Y-L., Tsao, S., Liao, C-C., Yu, F-L., Hung, C-S., Yang, Y-Y. & Wang, G-C., 2018, In : Journal of Biomedical & Laboratory Sciences. 30, 1, p. 14-23 10 p.

Research output: Contribution to journalArticle

Tuberculosis
Sensitivity and Specificity
Mycobacterium tuberculosis
Cross-Priming
DNA
2017
4 Citations (Scopus)

Single chain antibody fragment against venom from the snake Daboia russelii formosensis

Lee, C. H., Lee, Y. C., Lee, Y. L., Leu, S. J., Lin, L. T., Chen, C. C., Chiang, J. R., Fellow, P., Tsai, B. Y., Hung, C. S. & Yang, Y. Y., Nov 1 2017, In : Toxins. 9, 11, 347.

Research output: Contribution to journalArticle

Single-Chain Antibodies
Immunoglobulin Fragments
Snake Venoms
Venoms
Bacteriophages
10 Citations (Scopus)

Valproic Acid and Lithium Meditate Anti-Inflammatory Effects by Differentially Modulating Dendritic Cell Differentiation and Function

Leu, S. J., Yang, Y. Y., Liu, H. C., Cheng, C. Y., Wu, Y. C., Huang, M. C., Lee, Y. L., Chen, C. C., Shen, W. W. & Liu, K. J., May 1 2017, In : Journal of Cellular Physiology. 232, 5, p. 1176-1186 11 p.

Research output: Contribution to journalArticle

Valproic Acid
Lithium
Dendritic Cells
Cell Differentiation
Anti-Inflammatory Agents
2016
11 Citations (Scopus)

Antibodies against venom of the snake Deinagkistrodon acutus

Lee, C. H., Lee, Y. C., Liang, M. H., Leu, S. J., Lin, L. T., Chiang, J. R. & Yang, Y. Y., 2016, In : Applied and Environmental Microbiology. 82, 1, p. 71-80 10 p.

Research output: Contribution to journalArticle

venom
Snake Venoms
venoms
snake
snakes
3 Citations (Scopus)

Evaluation of a modified direct agar proportion method for testing susceptibility of Mycobacterium tuberculosis from MGIT samples

Yu, F. L., Lee, J. C., Wang, M. S., Hsu, H. L., Chen, T. T., Cheng, C. L., Yang, Y. Y., Wang, G. C. & Yu, M. C., Feb 1 2016, In : Journal of Microbiology, Immunology and Infection. 49, 1, p. 60-65 6 p.

Research output: Contribution to journalArticle

Mycobacterium tuberculosis
Agar
Tuberculosis
Pharmaceutical Preparations
Costs and Cost Analysis
20 Citations (Scopus)

From the fluorescent lamp-induced bactericidal performance of sputtered Ag/TiO2 films to re-explore the photocatalytic mechanism

Kuo, D. H., Hsu, W. T. & Yang, Y. Y., May 5 2016, In : Applied Catalysis B: Environmental. 184, p. 191-200 10 p.

Research output: Contribution to journalArticle

Fluorescent lamps
Bactericides
Escherichia coli
annealing
Cermet Cements
9 Citations (Scopus)

Production and characterization of neutralizing antibodies against Bungarus multicinctus snake venom

Lee, C. H., Lee, Y-C., Leu, S-J., Lin, L-T., Chiang, J. R., Hsu, W. J. & Yang, Y-Y., 2016, In : Applied and Environmental Microbiology. 82, 23, p. 6973-6982 10 p.

Research output: Contribution to journalArticle

Bungarus
venom
Single-Chain Antibodies
Snake Venoms
venoms
2 Citations (Scopus)

Recombinant OmpA protein fragments mediate interleukin-17 regulation to prevent Escherichia coli meningitis

Hsieh, W. S., Yang, Y. Y., Lin, P. H., Chang, C. C. & Wu, H. H., Dec 1 2016, In : Journal of Microbiology, Immunology and Infection. 49, 6

Research output: Contribution to journalArticle

Escherichia coli Meningitis
Escherichia coli Infections
Interleukin-17
Recombinant Proteins
Chemokines
4 Citations (Scopus)

Recombinant outer membrane protein A fragments protect against Escherichia coli meningitis

Hsieh, W. S., Yang, Y. Y., Yang, H. Y., Huang, Y. S. & Wu, H. H., Jun 1 2016, In : Journal of Microbiology, Immunology and Infection. 49, 3, p. 329-334

Research output: Contribution to journalArticle

Escherichia coli Meningitis
Escherichia coli Infections
Escherichia coli
Meningitis
Protein Conformation
2015
12 Citations (Scopus)

Anti-a-enolase is a prognostic marker in postoperative lung cancer patients

Hsiao, K. C., Shih, N. Y., Chu, P. Y., Hung, Y. M., Liao, J. Y., Chou, S. W., Yang, Y. Y., Chang, G. C. & Liu, K. J., 2015, In : Oncotarget. 6, 33, p. 35073-35086 14 p.

Research output: Contribution to journalArticle

Phosphopyruvate Hydratase
Lung Neoplasms
Non-Small Cell Lung Carcinoma
Circulating Neoplastic Cells
Regulatory T-Lymphocytes
2 Citations (Scopus)

Single chain antibody fragment with serine protease inhibitory property capable of neutralizing toxicity of Trimeresurus mucrosquamatus venom

Lee, Y. C., Chen, W. C., Liang, M. H., Lee, C. H., Tsai, K. C., Chiang, J. R., Chiang, L. C., Chen, C. C., Chang, C. Y., Lee, C. H., Leu, S. J. & Yang, Y. Y., May 1 2015, In : Biochemical and Biophysical Research Communications. 460, 2, p. 170-176 7 p.

Research output: Contribution to journalArticle

Single-Chain Antibodies
Immunoglobulin Fragments
Serine Proteases
Toxicity
Snake Bites
2013
4 Citations (Scopus)

Isolation, characterization, and molecular modeling of a rheumatoid factor from a hepatitis C virus infected patient with sjögren's syndrome

Lee, Y. C., Tsai, K. C., Leu, S. J., Wang, T. J., Liu, C. Y. & Yang, Y. Y., 2013, In : Scientific World Journal. 2013, 516516.

Research output: Contribution to journalArticle

hepatitis
Molecular modeling
Rheumatoid Factor
complementarity
Viruses
49 Citations (Scopus)

Surface α-Enolase Promotes Extracellular Matrix Degradation and Tumor Metastasis and Represents a New Therapeutic Target

Hsiao, K. C., Shih, N. Y., Fang, H. L., Huang, T. S., Kuo, C. C., Chu, P. Y., Hung, Y. M., Chou, S. W., Yang, Y. Y., Chang, G. C. & Liu, K. J., Jul 19 2013, In : PLoS One. 8, 7, e69354.

Research output: Contribution to journalArticle

phosphopyruvate hydratase
Phosphopyruvate Hydratase
extracellular matrix
metastasis
Extracellular Matrix
13 Citations (Scopus)
Regulatory T-Lymphocytes
Immunosuppressive Agents
Blood Platelets
Asthma
T-Lymphocytes
2012
8 Citations (Scopus)

A real time detection of the ovarian tumor associated antigen 1 (OVTA 1) in human serum by quartz crystal microbalance immobilized with anti-OVTA 1 polyclonal chicken IgY antibodies

Sadhasivam, S., Chen, J. C., Savitha, S., Lin, F. H., Yang, Y. Y. & Lee, C. H., Oct 1 2012, In : Materials Science and Engineering C. 32, 7, p. 2073-2078 6 p.

Research output: Contribution to journalArticle

chickens
Quartz crystal microbalances
antigens
Antigens
quartz crystals
2011
7 Citations (Scopus)

Carbon tetrachloride-induced hepatotoxicity and its amelioration by Agaricus blazei Murrill extract in a mouse model

Chang, J. B., Wu, M. F., Yang, Y. Y., Leu, S. J., Chen, Y. L., Yu, C. S., Yu, C. C., Chang, S. J., Lu, H. F. & Chung, J. G., Nov 2011, In : In Vivo. 25, 6, p. 971-976 6 p.

Research output: Contribution to journalArticle

Agaricus
Carbon Tetrachloride
Aspartate Aminotransferases
Alanine Transaminase
Glutathione Peroxidase
10 Citations (Scopus)

Evaluation of genotoxicity of Antrodia cinnamomea in the Ames test and the in vitro chromosomal aberration test

Wu, M. F., Peng, F. C., Chen, Y. L., Lee, C. S., Yang, Y. Y., Yeh, M. Y., Liu, C. M., Chang, J. B., Wu, R. S. C., Yu, C. C., Lu, H. F. & Chung, J. G., May 2011, In : In Vivo. 25, 3, p. 419-423 5 p.

Research output: Contribution to journalArticle

Antrodia
Fungi
Aberrations
Chromosome Aberrations
Salmonella
14 Citations (Scopus)

Identification of salt-inducible kinase 3 as a novel tumor antigen associated with tumorigenesis of ovarian cancer

Charoenfuprasert, S., Yang, Y. Y., Lee, Y. C., Chao, K. C., Chu, P. Y., Lai, C. R., Hsu, K. F., Chang, K. C., Chen, Y. C., Chen, L. T., Chang, J. Y., Leu, S. J. & Shih, N. Y., Aug 18 2011, In : Oncogene. 30, 33, p. 3570-3584 15 p.

Research output: Contribution to journalArticle

Neoplasm Antigens
Ovarian Neoplasms
Carcinogenesis
Phosphotransferases
Salts
21 Citations (Scopus)

Modulation of the development of human monocyte-derived dendritic cells by lithium chloride

Liu, K. J., Lee, Y. L., Yang, Y. Y., Shih, N. Y., Ho, C. C., Wu, Y. C., Huang, T. S., Huang, M. C., Liu, H. C., Shen, W. W. & Leu, S. J., Feb 2011, In : Journal of Cellular Physiology. 226, 2, p. 424-433 10 p.

Research output: Contribution to journalArticle

Lithium Chloride
Human Development
Dendritic Cells
Monocytes
Modulation
77 Citations (Scopus)

Nicotine-induced human breast cancer cell proliferation attenuated by garcinol through down-regulation of the nicotinic receptor and cyclin D3 proteins

Chen, C. S., Lee, C-H., Hsieh, C. D., Ho, C. T., Pan, M. H., Huang, C. S., Tu, S-H., Wang, Y. J., Chen, L-C., Chang, Y-J., Wei, P-L., Yang, Y-Y., Wu, C-H. & Ho, Y-S., Jan 2011, In : Breast Cancer Research and Treatment. 125, 1, p. 73-87 15 p.

Research output: Contribution to journalArticle

Cyclin D3
Nicotinic Receptors
Nicotine
Down-Regulation
Cell Proliferation
6 Citations (Scopus)

Possible reduction of hepatoma formation by Smmu 7721 cells in SCID mice and metastasis formation by B16F10 melanoma cells in C57BL/6 mice by Agaricus blazei murill extract

Wu, M. F., Lu, H. F., Hsu, Y. M., Tang, M. C., Chen, H. C., Lee, C. S., Yang, Y. Y., Yeh, M. Y., Chung, H. K., Huang, Y. P., Wu, C. C. & Chung, J. G., May 2011, In : In Vivo. 25, 3, p. 399-404 6 p.

Research output: Contribution to journalArticle

Agaricus
Severe Combined Immunodeficiency
Inbred C57BL Mouse
Tumors
Hepatocellular Carcinoma
2010
71 Citations (Scopus)

Antitumor activity of capsaicin on human colon cancer cells in vitro and colo 205 tumor xenografts in vivo

Lu, H. F., Chen, Y. L., Yang, J. S., Yang, Y. Y., Liu, J. Y., Hsu, S. C., Lai, K. C. & Chung, J. G., Dec 22 2010, In : Journal of Agricultural and Food Chemistry. 58, 24, p. 12999-13005 7 p.

Research output: Contribution to journalArticle

capsaicin
Capsaicin
colorectal neoplasms
Heterografts
Colonic Neoplasms
48 Citations (Scopus)

Combination treatment with luteolin and quercetin enhances antiproliferative effects in nicotine-treated MDA-MB-231 cells by down-regulating nicotinic acetylcholine receptors

Shih, Y. L., Liu, H. C., Chen, C. S., Hsu, C-H., Pan, M. H., Chang, H. W., Chang, C. H., Chen, F. C., Ho, C. T., Yang, Y-Y. & Ho, Y-S., Jan 13 2010, In : Journal of Agricultural and Food Chemistry. 58, 1, p. 235-241 7 p.

Research output: Contribution to journalArticle

Luteolin
cholinergic receptors
nicotine
luteolin
Quercetin
9 Citations (Scopus)

Generation and characterization of anti-α-enolase single-chain antibodies in chicken

Leu, S. J., Lee, Y. C., Shih, N. Y., Huang, I. J., Liu, K. J., Lu, H. F., Huang, S. Y. & Yang, Y. Y., Oct 2010, In : Veterinary Immunology and Immunopathology. 137, 3-4, p. 251-260 10 p.

Research output: Contribution to journalArticle

Single-Chain Antibodies
phosphopyruvate hydratase
Phosphopyruvate Hydratase
Chickens
chickens
24 Citations (Scopus)

Knockdown of thrombomodulin enhances HCC cell migration through increase of ZEB1 and decrease of E-cadherin gene expression

Huang, M. T., Wei, P. L., Liu, J. J., Liu, D. Z., Huang, H. C., An, J., Wu, C. C., Wu, C. H., Ho, Y. S., Yang, Y. Y. & Chang, Y. J., Dec 2010, In : Annals of Surgical Oncology. 17, 12, p. 3379-3385 7 p.

Research output: Contribution to journalArticle

Thrombomodulin
Cadherins
Cell Movement
Hepatocellular Carcinoma
Gene Expression
4 Citations (Scopus)

Nonmuscle myosin IIA (myosin heavy polypeptide 9): A novel class of signal transducer mediating the activation of Gαh/phospholipase C-δ1 pathway

Lin, Y. F., Yeh, T. S., Chen, S. F., Tsai, Y. H., Chou, C. M., Yang, Y. Y. & Huang, H. M., Mar 2010, In : Endocrinology. 151, 3, p. 876-885 10 p.

Research output: Contribution to journalArticle

Nonmuscle Myosin Type IIA
FSH Receptors
Sertoli Cells
Type C Phospholipases
Myosins
2009
14 Citations (Scopus)

OmpA is the critical component for escherichia coli invasion-induced astrocyte activation

Wu, H. H., Yang, Y. Y., Hsieh, W. S., Lee, C. H., Leu, S. J. C. & Chen, M. R., Jun 2009, In : Journal of Neuropathology and Experimental Neurology. 68, 6, p. 677-690 14 p.

Research output: Contribution to journalArticle

Astrocytes
Escherichia coli
Escherichia coli Meningitis
OMPA outer membrane proteins
1-Phosphatidylinositol 4-Kinase
8 Citations (Scopus)

Reduction of monocyte chemoattractant protein-1 and interleukin-8 levels by ticlopidine in TNF-α stimulated human umbilical vein endothelial cells

Hu, C. J., Lee, Y. L., Shih, N. Y., Yang, Y. Y., Charoenfuprasert, S., Dai, Y. S., Chang, S. M., Tsai, Y-H., Tseng, H., Liu, C. Y. & Leu, S. J., 2009, In : Journal of Biomedicine and Biotechnology. 2009, 917837.

Research output: Contribution to journalArticle

Ticlopidine
Chemokine CCL2
Endothelial cells
Human Umbilical Vein Endothelial Cells
Interleukin-8
95 Citations (Scopus)
Neprilysin
Endothelial cells
DNA Methylation
Amyloid
Epigenomics
57 Citations (Scopus)
Nicotinic Receptors
Carcinogens
Colonic Neoplasms
Tobacco
Cell Movement
2008
5 Citations (Scopus)

The effect of Chinese herbal medicines on TNF-α induced matrix metalloproteinase-1, -9 activities and interleukin-8 secretion

Lee, M. H., Yang, Y. Y., Tsai, Y-H., Lee, Y. L., Huang, P. Y., Huang, I. J., Cheng, K. T. & Leu, S. J., Oct 2008, In : Botanical Studies. 49, 4, p. 301-309 9 p.

Research output: Contribution to journalArticle

interstitial collagenase
herbal medicines
interleukin-8
skin (animal)
secretion
2007
25 Citations (Scopus)

(-)-Menthol inhibits WEHI-3 leukemia cells in vitro and in vivo

Lu, H. F., Liu, J. Y., Hsueh, S. C., Yang, Y. Y., Yang, J. S., Tan, T. W., Kok, L. F., Lu, C. C., Lan, S. H., Wu, S. Y., Liao, S. S., Ip, S. W. & Chung, J. G., Mar 2007, In : In Vivo. 21, 2, p. 285-289 5 p.

Research output: Contribution to journalArticle

Menthol
Leukemia
Mouthwashes
Toothpastes
Macrophages
13 Citations (Scopus)

A dominant antigenic epitope on SARS-CoV spike protein identified by an avian single-chain variable fragment (scFv)-expressing phage

Lee, Y. C., Leu, S. J. C., Hung, H. C., Wu, H. H., Huang, I. J., Hsieh, W. S., Chiu, W. T., Hsieh, M. S., Cheng, T. F. & Yang, Y. Y., May 15 2007, In : Veterinary Immunology and Immunopathology. 117, 1-2, p. 75-85 11 p.

Research output: Contribution to journalArticle

Avian Proteins
Severe Acute Respiratory Syndrome
Single-Chain Antibodies
bacteriophages
Bacteriophages
39 Citations (Scopus)

Carotenoids suppress proliferating cell nuclear antigen and cyclin D1 expression in oral carcinogenic models

Cheng, H. C., Chien, H., Liao, C. H., Yang, Y. Y. & Huang, S. Y., Oct 2007, In : Journal of Nutritional Biochemistry. 18, 10, p. 667-675 9 p.

Research output: Contribution to journalArticle

Cyclin D1
Proliferating Cell Nuclear Antigen
Carotenoids
Cell proliferation
KB Cells
3 Citations (Scopus)

Characterization of novel transforming growth factor-beta type I receptors found in malignant pleural effusion tumor cells

Chen, K. L., Liu, W. H., Yang, Y. Y., Leu, S. J. C. & Shih, N. Y., Aug 17 2007, In : BMC Molecular Biology. 8, 72.

Research output: Contribution to journalArticle

Malignant Pleural Effusion
Tumors
Protein Sorting Signals
Cells
Neoplasms
8 Citations (Scopus)

Chicken single-chain variable fragments against the SARS-CoV spike protein

Lee, Y. C., Leu, S. J. C., Hu, C. J., Shih, N. Y., Huang, I. J., Wu, H. H., Hsieh, W. S., Chiang, B. L., Chiu, W. T. & Yang, Y. Y., Dec 2007, In : Journal of Virological Methods. 146, 1-2, p. 104-111 8 p.

Research output: Contribution to journalArticle

Severe Acute Respiratory Syndrome
Single-Chain Antibodies
Chickens
Proteins
Bacteriophages
2006
9 Citations (Scopus)

Anti-heat shock protein 90 is increased in acute mania

Shen, W. W., Liu, H. C., Yang, Y. Y., Lin, C. Y., Chen, K. P., Tsai, T-S. & Leu, S. J., Aug 2006, In : Australian and New Zealand Journal of Psychiatry. 40, 8, p. 712-716 5 p.

Research output: Contribution to journalArticle

HSP90 Heat-Shock Proteins
Bipolar Disorder
Autoantibodies
Serum
Chaperonin 60
10 Citations (Scopus)
Extracellular Signal-Regulated MAP Kinases
Cyclooxygenase 2
Prostaglandin-Endoperoxide Synthases
Dinoprostone
Rats
2005
48 Citations (Scopus)

Infrared thermography to mass-screen suspected sars patients with fever

Chiu, W. T., Lin, P. W., Chiou, H. Y., Lee, W. S., Lee, C. N., Yang, Y. Y., Lee, H. M., Hsieh, M. S., Hu, C. J., Ho, Y. S., Deng, W. P. & Hsu, C. Y., 2005, In : Asia-Pacific Journal of Public Health. 17, 1, p. 26-28 3 p.

Research output: Contribution to journalArticle

Severe Acute Respiratory Syndrome
Fever
Visitors to Patients
Mass Screening
Cross Infection
2004
57 Citations (Scopus)

Aspirin inhibits monocyte chemoattractant protein-1 and interleukin-8 expression in TNF-α stimulated human umbilical vein endothelial cells

Yang, Y. Y., Hu, C. J., Chang, S. M., Tai, T. Y. & Leu, S. J., Jun 2004, In : Atherosclerosis. 174, 2, p. 207-213 7 p.

Research output: Contribution to journalArticle

Chemokine CCL2
Human Umbilical Vein Endothelial Cells
Interleukin-8
Aspirin
Atherosclerosis
103 Citations (Scopus)

Immunologic variables in acute mania of bipolar disorder

Liu, H. C., Yang, Y. Y., Chou, Y. M., Chen, K. P., Shen, W. W. & Leu, S. J., May 2004, In : Journal of Neuroimmunology. 150, 1-2, p. 116-122 7 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Interleukins
Cytokines
Interleukin-4
Interleukin-10
2003

Detection and investigation of TT virus infection in Taiwanese population

Chiu, Y-Y., Yeung, C. Y., Leu, S-J., Hsieh, W. S., Hsieh, M-S. & Yang, Y-Y., 2003, In : J. Biomedical and Laboratory Sciences. 15, p. 27-34 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
Mood Disorders
Bipolar Disorder
Interleukin-10
Interferon-gamma
2002

Contribution of heavy chain genes on the binding property of a recombinant human IgG rheumatoid factor

Lee, Y-C., Leu, S-J., Hsieh, M-S., Huang, I. J. & Yang, Y-Y., 2002, In : J. Biomedical and Laboratory Sciences. 14, p. 89-94 6 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)
Bipolar Disorder
Interleukin-10
Interferon-gamma
Interleukin-2 Receptors
Phytohemagglutinins
2001
85 Citations (Scopus)

Effects of symptomatic severity on elevation of plasma soluble interleukin-2 receptor in bipolar mania

Tsai, S. Y. M., Yang, Y. Y., Kuo, C. J., Chen, C. C. & Leu, S. J. C., 2001, In : Journal of Affective Disorders. 64, 2-3, p. 185-193 9 p.

Research output: Contribution to journalArticle

Interleukin-2 Receptors
Bipolar Disorder
Schizophrenia
Interleukin-6 Receptors
Depressive Disorder
1999
98 Citations (Scopus)

Activation of indices of cell-mediated immunity in bipolar mania

Tsai, S. Y., Chen, K. P., Yang, Y. Y., Chen, C. C., Lee, J. C., Singh, V. K. & Leu, S. J. C., Apr 15 1999, In : Biological Psychiatry. 45, 8, p. 989-994 6 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Cellular Immunity
Phytohemagglutinins
Lymphocytes
Pokeweed Mitogens
11 Citations (Scopus)

Possible presence of enhancing antibodies in idiopathic thrombocytopenic purpura

Yang, Y. Y., Fischer, P., Leu, S. J., Zhu, M., Woods, V. L. & Chen, P. P., 1999, In : British Journal of Haematology. 104, 1, p. 69-80 12 p.

Research output: Contribution to journalArticle

Blocking Antibodies
Idiopathic Thrombocytopenic Purpura
Rheumatoid Factor
Immunoglobulin G
Autoantibodies