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Research Output 2009 2019

  • 261 Citations
  • 8 h-Index
  • 37 Article
  • 3 Letter
  • 1 Comment/debate
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Article
2019

Enhanced cytotoxicity of human hepatocellular carcinoma cells following pretreatment with sorafenib combined with trichostatin A

Chen, J. C. H., Chuang, H. Y., Liao, Y. J., Hsu, F. T., Chen, Y. C., Wang, W. H. & Hwang, J. J., Jan 1 2019, In : Oncology Letters. 17, 1, p. 638-645 8 p.

Research output: Contribution to journalArticle

trichostatin A
Hepatocellular Carcinoma
Extracellular Signal-Regulated MAP Kinases
Mitogen-Activated Protein Kinase Kinases
sorafenib

Ex vivo expanded human Vγ9vδ2 T-cells can suppress epithelial ovarian cancer cell growth

Mao, T. L., Miao, C. H., Liao, Y. J., Chen, Y. J., Yeh, C. Y. & Liu, C. L., Mar 1 2019, In : International Journal of Molecular Sciences. 20, 5, 1139.

Research output: Contribution to journalArticle

Open Access
T-cells
Cell growth
cancer
Tumors
T-Lymphocytes

Respective radiation output characteristics of transmission-target and reflection-target X-ray tubes with the same beam quality

Wang, S. F., Chiang, H. Y., Liao, Y. J., Liu, R. S., Cheng, C. C., Yang, H. W., Wang, S. W., Lin, Y. C. & Hsu, S. M., May 1 2019, In : Radiation Physics and Chemistry. 158, p. 188-193 6 p.

Research output: Contribution to journalArticle

tubes
output
radiation
x rays
dosage

TGF-β regulated leukemia cell susceptibility against NK targeting through the down-regulation of the CD48 expression

Huang, C. H., Liao, Y. J., Chiou, T. J., Huang, H. T., Lin, Y. H. & Twu, Y. C., Jan 1 2019, In : Immunobiology.

Research output: Contribution to journalArticle

Transforming Growth Factors
Leukemia
Down-Regulation
Natural Killer Cells
Intercellular Adhesion Molecule-1

Treatment with a new benzimidazole derivative bearing a pyrrolidine side chain overcomes sorafenib resistance in hepatocellular carcinoma

Suk, F. M., Liu, C. L., Hsu, M. H., Chuang, Y. T., Wang, J. P. & Liao, Y. J., Dec 1 2019, In : Scientific Reports. 9, 1, 17259.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Therapeutics
Epithelial-Mesenchymal Transition
Heterografts
Glypicans
2018
2 Citations (Scopus)

AAV serotype 8-mediated liver specific GNMT expression delays progression of hepatocellular carcinoma and prevents carbon tetrachloride-induced liver damage

Fang, C. C., Wu, C. F., Liao, Y. J., Huang, S. F., Chen, M. & Chen, Y. M. A., Dec 1 2018, In : Scientific Reports. 8, 1, 13802.

Research output: Contribution to journalArticle

Glycine N-Methyltransferase
Dependovirus
Carbon Tetrachloride
Hepatocellular Carcinoma
Liver
3 Citations (Scopus)

A developed NK-92MI cell line with siglec-7neg phenotype exhibits high and sustainable cytotoxicity against leukemia cells

Huang, C. H., Liao, Y. J., Fan, T. H., Chiou, T. J., Lin, Y. H. & Twu, Y. C., Apr 4 2018, In : International Journal of Molecular Sciences. 19, 4, 1073.

Research output: Contribution to journalArticle

Sialic Acid Binding Immunoglobulin-like Lectins
phenotype
leukemias
Cytotoxicity
cultured cells
5 Citations (Scopus)

Niemann-pick type C2 protein regulates free cholesterol accumulation and influences hepatic stellate cell proliferation and mitochondrial respiration function

Wang, Y. H., Twu, Y. C., Wang, C. K., Lin, F. Z., Lee, C. Y. & Liao, Y. J., Jun 1 2018, In : International Journal of Molecular Sciences. 19, 6, 1678.

Research output: Contribution to journalArticle

Hepatic Stellate Cells
Cholesterol
cholesterol
respiration
Cell proliferation
2017
1 Citation (Scopus)

Branched I antigens on leukemia cells enhanced sensitivity against natural killer–cell cytotoxicity through affecting the target–effector interaction

Lee, Y. H., Liao, Y. J., Huang, C. H., Chang, F. L., Fan, T. H. & Twu, Y. C., Apr 1 2017, In : Transfusion. 57, 4, p. 1040-1051 12 p.

Research output: Contribution to journalArticle

Leukemia
Natural Killer Cells
Tumor-Associated Carbohydrate Antigens
Neoplasm Metastasis
Ligands
1 Citation (Scopus)

Characterization of a new murine cell line of sarcomatoid hepatocellular carcinoma and its application for biomarker/therapy development

Yen, C. H., Lai, C. C., Liao, C. C., Wang, S. F., Liao, Y. J., Tung, C. Y., Hung, J. H., Huang, S. F. & Chen, Y. M. A., Dec 1 2017, In : Scientific Reports. 7, 1, 3052.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Biomarkers
Cell Line
Vimentin
Therapeutics
1 Citation (Scopus)

Feasibility study on applying radiophotoluminescent glass dosimeters for cyberknife srs dose verification

Hsu, S. M., Hung, C. H., Liao, Y. J., Fu, H. M., Tsai, J. T., Huang, Y. H. & Huang, D. Y. C., Jan 1 2017, In : PLoS One. 12, 1, e0169252.

Research output: Contribution to journalArticle

Dosimeters
Feasibility Studies
Dosimetry
Glass
glass
5 Citations (Scopus)

Impact of radiation attenuation by a carbon fiber couch on patient dose verification

Yu, C. Y., Chou, W. T., Liao, Y. J., Lee, J. H., Liang, J. A. & Hsu, S. M., Feb 27 2017, In : Scientific Reports. 7, 43336.

Research output: Contribution to journalArticle

couches
carbon fibers
attenuation
dosage
radiation
4 Citations (Scopus)

Treatment with low-dose sorafenib in combination with a novel benzimidazole derivative bearing a pyrolidine side chain provides synergistic anti-proliferative effects against human liver cancer

Hsu, M. H., Hsu, S. M., Kuo, Y. C., Liu, C. Y., Hsieh, C. Y., Twu, Y. C., Wang, C. K., Wang, Y. H. & Liao, Y. J., 2017, In : RSC Advances. 7, 26, p. 16253-16263 11 p.

Research output: Contribution to journalArticle

Bearings (structural)
Cell proliferation
Liver
Phosphorylation
Derivatives
2016
2 Citations (Scopus)

A volume-equivalent spherical necrosis-tumor-normal liver model for estimating absorbed dose in yttrium-90 microsphere therapy

Wu, C. H., Liao, Y. J., Lin, T. Y., Chen, C. Y., Sun, S. S., Liu, Y. W. H. & Hsu, S. M., Nov 1 2016, In : Medical Physics. 43, 11, p. 6082-6088 7 p.

Research output: Contribution to journalArticle

Yttrium
Microspheres
Necrosis
Liver
Neoplasms
6 Citations (Scopus)

Design and synthesis of pyridine-pyrazole-sulfonate derivatives as potential anti-HBV agents

Chuang, H., Huang, L. C. S., Kapoor, M., Liao, Y. J., Yang, C. L., Chang, C. C., Wu, C. Y., Hwu, J. R., Huang, T. J. & Hsu, M. H., 2016, In : MedChemComm. 7, 5, p. 832-836 5 p.

Research output: Contribution to journalArticle

Viruses
Hepatitis B virus
Derivatives
Inhibitory Concentration 50
Nuclear magnetic resonance
5 Citations (Scopus)

Glycine N-methyltransferase deficiency in female mice impairs insulin signaling and promotes gluconeogenesis by modulating the PI3K/Akt pathway in the liver

Liao, Y. J., Lee, T. S., Twu, Y. C., Hsu, S. M., Yang, C. P., Wang, C. K., Liang, Y. C. & Chen, Y-M., Oct 4 2016, In : Journal of Biomedical Science. 23, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

Glycine N-Methyltransferase
Gluconeogenesis
Phosphatidylinositol 3-Kinases
Liver
Insulin
7 Citations (Scopus)

Niemann-Pick type C2 protein mediates hepatic stellate cells activation by regulating free cholesterol accumulation

Twu, Y. C., Lee, T. S., Lin, Y. L., Hsu, S. M., Wang, Y. H., Liao, C. Y., Wang, C. K., Liang, Y. C. & Liao, Y. J., Jul 13 2016, In : International Journal of Molecular Sciences. 17, 7, 1122.

Research output: Contribution to journalArticle

Hepatic Stellate Cells
Cholesterol
cholesterol
Chemical activation
activation
2 Citations (Scopus)

The SHP2-ERK2 signaling pathway regulates branched I antigen formation by controlling the binding of CCAAT/enhancer binding protein α to the IGnTC promoter region during erythroid differentiation

Liao, Y. J., Lee, Y. H., Chang, F. L., Ho, H., Huang, C. H. & Twu, Y. C., Nov 1 2016, In : Transfusion. 56, 11, p. 2691-2702 12 p.

Research output: Contribution to journalArticle

CCAAT-Enhancer-Binding Proteins
Genetic Promoter Regions
Phosphorylation
Surface Antigens
Granulocytes
2015

A novel simple phantom for verifying the dose of radiation therapy

Lee, J. H., Chang, L. T., Shiau, A. C., Chen, C. W., Liao, Y. J., Li, W. J., Lee, M. S. & Hsu, S. M., 2015, In : BioMed Research International. 2015, 934387.

Research output: Contribution to journalArticle

Radiotherapy
Dosimetry
Dosimeters
Water
Clinical Audit

HDR Brachytherapy Dose Distribution is Influenced by the Metal Material of the Applicator

Wu, C. H., Liao, Y. J., Shiau, A. C., Lin, H. Y., Hsueh Liu, Y. W. & Hsu, S. M., Dec 11 2015, In : Scientific Reports. 5, 17863.

Research output: Contribution to journalArticle

Brachytherapy
Metals
Rectum
Uterine Cervical Neoplasms
Urinary Bladder
12 Citations (Scopus)

Niemann-Pick type C2 protein regulates liver cancer progression via modulating ERK1/2 pathway: Clinicopathological correlations and therapeutical implications

Liao, Y. J., Fang, C. C., Yen, C. H., Hsu, S. M., Wang, C. K., Huang, S. F., Liang, Y. C., Lin, Y. Y., Chu, Y. T. & Chen, Y. M. A., Sep 1 2015, In : International Journal of Cancer. 137, 6, p. 1341-1351 11 p.

Research output: Contribution to journalArticle

MAP Kinase Signaling System
Liver Neoplasms
Hepatocellular Carcinoma
Proteins
Cholesterol
14 Citations (Scopus)

Role of phosphatase activity of soluble epoxide hydrolase in regulating simvastatin-activated endothelial nitric oxide synthase

Hou, H. H., Liao, Y. J., Hsiao, S. H., Shyue, S. K. & Lee, T. S., Aug 25 2015, In : Scientific Reports. 5, 13524.

Research output: Contribution to journalArticle

Epoxide Hydrolases
Simvastatin
Nitric Oxide Synthase Type III
Phosphoric Monoester Hydrolases
AMP-Activated Protein Kinases
2 Citations (Scopus)

The physical and biomedical characteristics of the novel transmission type X-ray equipment

Hsu, S. M., Wang, S. F., Hsieh, Y. J., Cheng, C. C. & Liao, Y. J., Oct 25 2015, (Accepted/In press) In : Radiation Measurements.

Research output: Contribution to journalArticle

X ray tubes
Wave transmission
Cytotoxicity
Radiation
X rays
2 Citations (Scopus)

The serologic decoy receptor 3 (DcR3) levels are associated with slower disease progression in HIV-1/AIDS patients

Lin, Y. T., Yen, C. H., Chen, H. L., Liao, Y. J., Lin, I. F., Chen, M., Lan, Y. C., Chuang, S. Y., Hsieh, S. L. & Chen, Y. M. A., Jun 1 2015, In : Journal of the Formosan Medical Association = Taiwan yi zhi. 114, 6, p. 498-503 6 p.

Research output: Contribution to journalArticle

Disease Progression
HIV-1
Acquired Immunodeficiency Syndrome
Fas Ligand Protein
Tumor Necrosis Factor Receptors
2014
2 Citations (Scopus)

Dose distributions of an 192Ir brachytherapy source in different media

Wu, C. H., Liao, Y. J., Liu, Y. W. H., Hung, S. K., Lee, M. S. & Hsu, S. M., 2014, In : BioMed Research International. 2014, 946213.

Research output: Contribution to journalArticle

Brachytherapy
Lung
Tissue
Anisotropy
Water
2 Citations (Scopus)

Influence of metal of the applicator on the dose distribution during brachytherapy

Wu, C. H., Shiau, A. C., Liao, Y. J., Lin, H. Y., Liu, Y. W. H. & Hsu, S. M., Aug 18 2014, In : PLoS One. 9, 8, e104831.

Research output: Contribution to journalArticle

Applicators
Brachytherapy
Metals
metals
Planning
2013
8 Citations (Scopus)

Characterization of Niemann-Pick Type C2 Protein Expression in Multiple Cancers Using a Novel NPC2 Monoclonal Antibody

Liao, Y. J., Lin, M. W., Yen, C. H., Lin, Y. T., Wang, C. K., Huang, S. F., Chen, K. H., Yang, C. P., Chen, T. L., Hou, M. F. & Arthur Chen, Y. M., Oct 17 2013, In : PLoS One. 8, 10, e77586.

Research output: Contribution to journalArticle

Liver
liver neoplasms
monoclonal antibodies
Liver Neoplasms
protein synthesis
7 Citations (Scopus)

Identification of FKBP11 as a biomarker for hepatocellular carcinoma

Lin, I. Y., Yen, C. H., Liao, Y. J., Lin, S-E., Ma, H. P., Chan, Y. J. & Chen, Y. M. A., Jun 2013, In : Anticancer Research. 33, 6, p. 2763-2770 8 p.

Research output: Contribution to journalArticle

Tacrolimus Binding Proteins
Glycine N-Methyltransferase
Hepatocellular Carcinoma
Biomarkers
Knockout Mice
2012
7 Citations (Scopus)

A Study on the Dose Distributions in Various Materials from an Ir-192 HDR Brachytherapy Source

Hsu, S. M., Wu, C. H., Lee, J. H., Hsieh, Y. J., Yu, C. Y., Liao, Y. J., Kuo, L. C., Liang, J. A. & Huang, D. Y. C., Sep 5 2012, In : PLoS One. 7, 9, e44528.

Research output: Contribution to journalArticle

Brachytherapy
Bone
lungs
bones
Water
16 Citations (Scopus)

Deficiency of Glycine N-methyltransferase aggravates atherosclerosis in apolipoprotein E-null mice

Chen, C. Y., Ching, L. C., Liao, Y. J., Yu, Y. B., Tsou, C. Y., Shyue, S. K., Chen, Y. M. A. & Lee, T. S., May 2012, In : Molecular Medicine. 18, 5, p. 744-752 9 p.

Research output: Contribution to journalArticle

Glycine N-Methyltransferase
Apolipoproteins E
Atherosclerosis
Macrophages
Cholesterol
32 Citations (Scopus)

Glycine N-methyltransferase deficiency affects Niemann-Pick type C2 protein stability and regulates hepatic cholesterol homeostasis.

Liao, Y. J., Chen, T. L., Lee, T. S., Wang, H. A., Wang, C. K., Liao, L. Y., Liu, R. S., Huang, S. F. & Chen, Y. M. A., 2012, In : Molecular Medicine. 18, 1, p. 412-422 11 p.

Research output: Contribution to journalArticle

Glycine N-Methyltransferase
Protein Stability
Homeostasis
Cholesterol
Liver
2011
4 Citations (Scopus)

Dose measurements for gamma knife with radiophotoluminescent glass dosemeter and radiochromic film

Hsu, S. M., Lee, J. H., Hsu, F. Y., Lee, H. W., Hung, S. K., Liao, Y. J. & Lee, M. S., Jul 2011, In : Radiation Protection Dosimetry. 146, 1-3, p. 256-259 4 p., ncr164.

Research output: Contribution to journalArticle

Glass
Head Protective Devices
dosage
Radiosurgery
glass
17 Citations (Scopus)

Higher susceptibility to aflatoxin B1-related hepatocellular carcinoma in glycine N-methyltransferase knockout mice

Liu, S. P., Li, Y. S., Lee, C. M., Yen, C. H., Liao, Y. J., Huang, S. F., Chien, C. H. & Chen, Y. M. A., Feb 1 2011, In : International Journal of Cancer. 128, 3, p. 511-523 13 p.

Research output: Contribution to journalArticle

Glycine N-Methyltransferase
Aflatoxin B1
Knockout Mice
Hepatocellular Carcinoma
Carcinogenesis
11 Citations (Scopus)

Radiation characteristics of homemade radiophotoluminescent glass dosimeter

Lee, M. S., Liao, Y. J., Huang, Y. H., Lee, J. H., Hung, S. K., Chen, T. R. & Hsu, S. M., Dec 2011, In : Radiation Measurements. 46, 12, p. 1477-1479 3 p.

Research output: Contribution to journalArticle

Dosimeters
dosimeters
Radiation
Glass
glass
2010
1 Citation (Scopus)

Chemical and physical characteristics of self-fabricated radiophotoluminescent glass dosimeter

Hsu, S. M., Yang, H. W., Huang, Y. H., Lee, J. H., Yu, C. Y., Liao, Y. J., Hung, S. K. & Lee, M. S., Mar 2010, In : Radiation Measurements. 45, 3-6, p. 553-555 3 p.

Research output: Contribution to journalArticle

Dosimeters
dosimeters
Glass
glass
chemical compounds
14 Citations (Scopus)

Deficiency of glycine N-methyltransferase results in deterioration of cellular defense to stress in mouse liver

Liao, Y. J., Chen, K. H., Huang, S. F., Chen, T. L., Wang, C. K., Chien, C. H., Tsai, T. F., Liu, S. P. & Chen, Y. M. A., Apr 2010, In : Proteomics - Clinical Applications. 4, 4, p. 394-406 13 p.

Research output: Contribution to journalArticle

Glycine N-Methyltransferase
Knockout Mice
Liver
Deterioration
Detoxification
2009
63 Citations (Scopus)

Characterization of a glycine N-methyltransferase gene knockout mouse model for hepatocellular carcinoma: Implications of the gender disparity in liver cancer susceptibility

Liao, Y. J., Liu, S. P., Lee, C. M., Yen, C. H., Chuang, P. C., Chen, C. Y., Tsai, T. F., Huang, S. F., Lee, Y. H. W. & Chen, Y. M. A., Feb 15 2009, In : International Journal of Cancer. 124, 4, p. 816-826 11 p.

Research output: Contribution to journalArticle

Glycine N-Methyltransferase
Gene Knockout Techniques
Liver Neoplasms
Knockout Mice
Hepatocellular Carcinoma