• 298 Citations
  • 10 h-Index
20092020

Research output per year

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Research Output

  • 298 Citations
  • 10 h-Index
  • 42 Article
  • 3 Letter
  • 1 Comment/debate
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Article
2020
Open Access
1 Citation (Scopus)

Engineering Chimeric Antigen Receptor T Cells against Immune Checkpoint Inhibitors PD-1/PD-L1 for Treating Pancreatic Cancer

Yang, C. Y., Fan, M. H., Miao, C. H., Liao, Y. J., Yuan, R. H. & Liu, C. L., Jun 26 2020, In : Molecular Therapy - Oncolytics. 17, p. 571-585 15 p.

Research output: Contribution to journalArticle

Open Access
Open Access

Treatment with a New Barbituric Acid Derivative Exerts Antiproliferative and Antimigratory Effects against Sorafenib Resistance in Hepatocellular Carcinoma

Liao, Y. J., Hsu, S. M., Chien, C. Y., Wang, Y. H., Hsu, M. H. & Suk, F. M., Jun 2020, In : Molecules. 25, 12, 285.

Research output: Contribution to journalArticle

Open Access
2019

Enhanced cytotoxicity of human hepatocellular carcinoma cells following pretreatment with sorafenib combined with trichostatin A

Chen, J. C. H., Chuang, H. Y., Liao, Y. J., Hsu, F. T., Chen, Y. C., Wang, W. H. & Hwang, J. J., Jan 1 2019, In : Oncology Letters. 17, 1, p. 638-645 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Ex vivo expanded human Vγ9vδ2 T-cells can suppress epithelial ovarian cancer cell growth

Mao, T. L., Miao, C. H., Liao, Y. J., Chen, Y. J., Yeh, C. Y. & Liu, C. L., Mar 1 2019, In : International Journal of Molecular Sciences. 20, 5, 1139.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

HMGCS2 mediates ketone production and regulates the proliferation and metastasis of hepatocellular carcinoma

Wang, Y. H., Liu, C. L., Chiu, W. C., Twu, Y. C. & Liao, Y. J., Dec 2019, In : Cancers. 11, 12, 1876.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Respective radiation output characteristics of transmission-target and reflection-target X-ray tubes with the same beam quality

Wang, S. F., Chiang, H. Y., Liao, Y. J., Liu, R. S., Cheng, C. C., Yang, H. W., Wang, S. W., Lin, Y. C. & Hsu, S. M., May 1 2019, In : Radiation Physics and Chemistry. 158, p. 188-193 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

TGF-β regulated leukemia cell susceptibility against NK targeting through the down-regulation of the CD48 expression

Huang, C. H., Liao, Y. J., Chiou, T. J., Huang, H. T., Lin, Y. H. & Twu, Y. C., Jan 1 2019, In : Immunobiology.

Research output: Contribution to journalArticle

Treatment with a new benzimidazole derivative bearing a pyrrolidine side chain overcomes sorafenib resistance in hepatocellular carcinoma

Suk, F. M., Liu, C. L., Hsu, M. H., Chuang, Y. T., Wang, J. P. & Liao, Y. J., Dec 1 2019, In : Scientific Reports. 9, 1, 17259.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2018

AAV serotype 8-mediated liver specific GNMT expression delays progression of hepatocellular carcinoma and prevents carbon tetrachloride-induced liver damage

Fang, C. C., Wu, C. F., Liao, Y. J., Huang, S. F., Chen, M. & Chen, Y. M. A., Dec 1 2018, In : Scientific Reports. 8, 1, 13802.

Research output: Contribution to journalArticle

2 Citations (Scopus)

A developed NK-92MI cell line with siglec-7neg phenotype exhibits high and sustainable cytotoxicity against leukemia cells

Huang, C. H., Liao, Y. J., Fan, T. H., Chiou, T. J., Lin, Y. H. & Twu, Y. C., Apr 4 2018, In : International Journal of Molecular Sciences. 19, 4, 1073.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Niemann-pick type C2 protein regulates free cholesterol accumulation and influences hepatic stellate cell proliferation and mitochondrial respiration function

Wang, Y. H., Twu, Y. C., Wang, C. K., Lin, F. Z., Lee, C. Y. & Liao, Y. J., Jun 1 2018, In : International Journal of Molecular Sciences. 19, 6, 1678.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2017

Branched I antigens on leukemia cells enhanced sensitivity against natural killer–cell cytotoxicity through affecting the target–effector interaction

Lee, Y. H., Liao, Y. J., Huang, C. H., Chang, F. L., Fan, T. H. & Twu, Y. C., Apr 1 2017, In : Transfusion. 57, 4, p. 1040-1051 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Characterization of a new murine cell line of sarcomatoid hepatocellular carcinoma and its application for biomarker/therapy development

Yen, C. H., Lai, C. C., Liao, C. C., Wang, S. F., Liao, Y. J., Tung, C. Y., Hung, J. H., Huang, S. F. & Chen, Y. M. A., Dec 1 2017, In : Scientific Reports. 7, 1, 3052.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Feasibility study on applying radiophotoluminescent glass dosimeters for cyberknife srs dose verification

Hsu, S. M., Hung, C. H., Liao, Y. J., Fu, H. M., Tsai, J. T., Huang, Y. H. & Huang, D. Y. C., Jan 1 2017, In : PLoS One. 12, 1, e0169252.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Impact of radiation attenuation by a carbon fiber couch on patient dose verification

Yu, C. Y., Chou, W. T., Liao, Y. J., Lee, J. H., Liang, J. A. & Hsu, S. M., Feb 27 2017, In : Scientific Reports. 7, 43336.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Treatment with low-dose sorafenib in combination with a novel benzimidazole derivative bearing a pyrolidine side chain provides synergistic anti-proliferative effects against human liver cancer

Hsu, M. H., Hsu, S. M., Kuo, Y. C., Liu, C. Y., Hsieh, C. Y., Twu, Y. C., Wang, C. K., Wang, Y. H. & Liao, Y. J., 2017, In : RSC Advances. 7, 26, p. 16253-16263 11 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2016

A volume-equivalent spherical necrosis-tumor-normal liver model for estimating absorbed dose in yttrium-90 microsphere therapy

Wu, C. H., Liao, Y. J., Lin, T. Y., Chen, C. Y., Sun, S. S., Liu, Y. W. H. & Hsu, S. M., Nov 1 2016, In : Medical Physics. 43, 11, p. 6082-6088 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Design and synthesis of pyridine-pyrazole-sulfonate derivatives as potential anti-HBV agents

Chuang, H., Huang, L. C. S., Kapoor, M., Liao, Y. J., Yang, C. L., Chang, C. C., Wu, C. Y., Hwu, J. R., Huang, T. J. & Hsu, M. H., 2016, In : MedChemComm. 7, 5, p. 832-836 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Glycine N-methyltransferase deficiency in female mice impairs insulin signaling and promotes gluconeogenesis by modulating the PI3K/Akt pathway in the liver

Liao, Y. J., Lee, T. S., Twu, Y. C., Hsu, S. M., Yang, C. P., Wang, C. K., Liang, Y. C. & Chen, Y-M., Oct 4 2016, In : Journal of Biomedical Science. 23, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Niemann-Pick type C2 protein mediates hepatic stellate cells activation by regulating free cholesterol accumulation

Twu, Y. C., Lee, T. S., Lin, Y. L., Hsu, S. M., Wang, Y. H., Liao, C. Y., Wang, C. K., Liang, Y. C. & Liao, Y. J., Jul 13 2016, In : International Journal of Molecular Sciences. 17, 7, 1122.

Research output: Contribution to journalArticle

10 Citations (Scopus)

The SHP2-ERK2 signaling pathway regulates branched I antigen formation by controlling the binding of CCAAT/enhancer binding protein α to the IGnTC promoter region during erythroid differentiation

Liao, Y. J., Lee, Y. H., Chang, F. L., Ho, H., Huang, C. H. & Twu, Y. C., Nov 1 2016, In : Transfusion. 56, 11, p. 2691-2702 12 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2015

A novel simple phantom for verifying the dose of radiation therapy

Lee, J. H., Chang, L. T., Shiau, A. C., Chen, C. W., Liao, Y. J., Li, W. J., Lee, M. S. & Hsu, S. M., 2015, In : BioMed Research International. 2015, 934387.

Research output: Contribution to journalArticle

HDR Brachytherapy Dose Distribution is Influenced by the Metal Material of the Applicator

Wu, C. H., Liao, Y. J., Shiau, A. C., Lin, H. Y., Hsueh Liu, Y. W. & Hsu, S. M., Dec 11 2015, In : Scientific Reports. 5, 17863.

Research output: Contribution to journalArticle

Niemann-Pick type C2 protein regulates liver cancer progression via modulating ERK1/2 pathway: Clinicopathological correlations and therapeutical implications

Liao, Y. J., Fang, C. C., Yen, C. H., Hsu, S. M., Wang, C. K., Huang, S. F., Liang, Y. C., Lin, Y. Y., Chu, Y. T. & Chen, Y. M. A., Sep 1 2015, In : International Journal of Cancer. 137, 6, p. 1341-1351 11 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Role of phosphatase activity of soluble epoxide hydrolase in regulating simvastatin-activated endothelial nitric oxide synthase

Hou, H. H., Liao, Y. J., Hsiao, S. H., Shyue, S. K. & Lee, T. S., Aug 25 2015, In : Scientific Reports. 5, 13524.

Research output: Contribution to journalArticle

16 Citations (Scopus)

The physical and biomedical characteristics of the novel transmission type X-ray equipment

Hsu, S. M., Wang, S. F., Hsieh, Y. J., Cheng, C. C. & Liao, Y. J., Oct 25 2015, (Accepted/In press) In : Radiation Measurements.

Research output: Contribution to journalArticle

3 Citations (Scopus)

The serologic decoy receptor 3 (DcR3) levels are associated with slower disease progression in HIV-1/AIDS patients

Lin, Y. T., Yen, C. H., Chen, H. L., Liao, Y. J., Lin, I. F., Chen, M., Lan, Y. C., Chuang, S. Y., Hsieh, S. L. & Chen, Y. M. A., Jun 1 2015, In : Journal of the Formosan Medical Association = Taiwan yi zhi. 114, 6, p. 498-503 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2014

Dose distributions of an 192Ir brachytherapy source in different media

Wu, C. H., Liao, Y. J., Liu, Y. W. H., Hung, S. K., Lee, M. S. & Hsu, S. M., 2014, In : BioMed Research International. 2014, 946213.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Influence of metal of the applicator on the dose distribution during brachytherapy

Wu, C. H., Shiau, A. C., Liao, Y. J., Lin, H. Y., Liu, Y. W. H. & Hsu, S. M., Aug 18 2014, In : PLoS One. 9, 8, e104831.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2013

Characterization of Niemann-Pick Type C2 Protein Expression in Multiple Cancers Using a Novel NPC2 Monoclonal Antibody

Liao, Y. J., Lin, M. W., Yen, C. H., Lin, Y. T., Wang, C. K., Huang, S. F., Chen, K. H., Yang, C. P., Chen, T. L., Hou, M. F. & Arthur Chen, Y. M., Oct 17 2013, In : PLoS One. 8, 10, e77586.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Identification of FKBP11 as a biomarker for hepatocellular carcinoma

Lin, I. Y., Yen, C. H., Liao, Y. J., Lin, S-E., Ma, H. P., Chan, Y. J. & Chen, Y. M. A., Jun 2013, In : Anticancer Research. 33, 6, p. 2763-2770 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2012

A Study on the Dose Distributions in Various Materials from an Ir-192 HDR Brachytherapy Source

Hsu, S. M., Wu, C. H., Lee, J. H., Hsieh, Y. J., Yu, C. Y., Liao, Y. J., Kuo, L. C., Liang, J. A. & Huang, D. Y. C., Sep 5 2012, In : PLoS One. 7, 9, e44528.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Deficiency of Glycine N-methyltransferase aggravates atherosclerosis in apolipoprotein E-null mice

Chen, C. Y., Ching, L. C., Liao, Y. J., Yu, Y. B., Tsou, C. Y., Shyue, S. K., Chen, Y. M. A. & Lee, T. S., May 2012, In : Molecular Medicine. 18, 5, p. 744-752 9 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Glycine N-methyltransferase deficiency affects Niemann-Pick type C2 protein stability and regulates hepatic cholesterol homeostasis.

Liao, Y. J., Chen, T. L., Lee, T. S., Wang, H. A., Wang, C. K., Liao, L. Y., Liu, R. S., Huang, S. F. & Chen, Y. M. A., 2012, In : Molecular Medicine. 18, 1, p. 412-422 11 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)
2011

Dose measurements for gamma knife with radiophotoluminescent glass dosemeter and radiochromic film

Hsu, S. M., Lee, J. H., Hsu, F. Y., Lee, H. W., Hung, S. K., Liao, Y. J. & Lee, M. S., Jul 2011, In : Radiation Protection Dosimetry. 146, 1-3, p. 256-259 4 p., ncr164.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Higher susceptibility to aflatoxin B1-related hepatocellular carcinoma in glycine N-methyltransferase knockout mice

Liu, S. P., Li, Y. S., Lee, C. M., Yen, C. H., Liao, Y. J., Huang, S. F., Chien, C. H. & Chen, Y. M. A., Feb 1 2011, In : International Journal of Cancer. 128, 3, p. 511-523 13 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Radiation characteristics of homemade radiophotoluminescent glass dosimeter

Lee, M. S., Liao, Y. J., Huang, Y. H., Lee, J. H., Hung, S. K., Chen, T. R. & Hsu, S. M., Dec 2011, In : Radiation Measurements. 46, 12, p. 1477-1479 3 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2010

Chemical and physical characteristics of self-fabricated radiophotoluminescent glass dosimeter

Hsu, S. M., Yang, H. W., Huang, Y. H., Lee, J. H., Yu, C. Y., Liao, Y. J., Hung, S. K. & Lee, M. S., Mar 2010, In : Radiation Measurements. 45, 3-6, p. 553-555 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Deficiency of glycine N-methyltransferase results in deterioration of cellular defense to stress in mouse liver

Liao, Y. J., Chen, K. H., Huang, S. F., Chen, T. L., Wang, C. K., Chien, C. H., Tsai, T. F., Liu, S. P. & Chen, Y. M. A., Apr 2010, In : Proteomics - Clinical Applications. 4, 4, p. 394-406 13 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2009

Characterization of a glycine N-methyltransferase gene knockout mouse model for hepatocellular carcinoma: Implications of the gender disparity in liver cancer susceptibility

Liao, Y. J., Liu, S. P., Lee, C. M., Yen, C. H., Chuang, P. C., Chen, C. Y., Tsai, T. F., Huang, S. F., Lee, Y. H. W. & Chen, Y. M. A., Feb 15 2009, In : International Journal of Cancer. 124, 4, p. 816-826 11 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)