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Article
2020

Effects of ANP on pulmonary vein electrophysiology, Ca2+ homeostasis and adrenergic arrhythmogenesis via PKA

Lu, Y. Y., Cheng, C. C., Wu, H. J., Lin, Y. K., Chen, Y. C., Chen, S. A. & Chen, Y. J., Feb 1 2020, In : Clinical and Experimental Pharmacology and Physiology. 47, 2, p. 247-254 8 p.

Research output: Contribution to journalArticle

Macrophage migration inhibitory factor increases atrial arrhythmogenesis through CD74 signaling

Cheng, W. L., Kao, Y. H., Chen, Y. C., Lin, Y. K., Chen, S. A. & Chen, Y. J., Feb 2020, In : Translational Research. 216, p. 43-56 14 p.

Research output: Contribution to journalArticle

2019

Arginine vasopressin modulates electrical activity and calcium homeostasis in pulmonary vein cardiomyocytes

Huang, J. H., Chen, Y. C., Lu, Y. Y., Lin, Y. K., Chen, S. A. & Chen, Y. J., Sep 17 2019, In : Journal of Biomedical Science. 26, 1, 71.

Research output: Contribution to journalArticle

Open Access
Open Access
5 Citations (Scopus)
3 Citations (Scopus)

MicroRNA-133 suppresses ZFHX3-dependent atrial remodelling and arrhythmia

Cheng, W. L., Kao, Y. H., Chao, T. F., Lin, Y. K., Chen, S. A. & Chen, Y. J., Jan 1 2019, (Accepted/In press) In : Acta Physiologica. e13322.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Pitx2c inhibition increases atrial fibroblast activity: Implications in atrial arrhythmogenesis

Kao, Y. H., Chung, C. C., Cheng, W. L., Lkhagva, B. & Chen, Y. J., Oct 1 2019, In : European Journal of Clinical Investigation. 49, 10, e13160.

Research output: Contribution to journalArticle

Sodium hydrosulphide restores tumour necrosis factor-α-induced mitochondrial dysfunction and metabolic dysregulation in HL-1 cells

Lee, T. I., Kao, Y. H., Baigalmaa, L., Lee, T. W., Lu, Y. Y., Chen, Y. C., Chao, T. F. & Chen, Y. J., Jan 1 2019, (Accepted/In press) In : Journal of Cellular and Molecular Medicine.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
2018

Activation of Class I histone deacetylases contributes to mitochondrial dysfunction in cardiomyocytes with altered complex activities

Lkhagva, B., Kao, Y. H., Lee, T. I., Lee, T. W., Cheng, W. L. & Chen, Y. J., May 1 2018, (Accepted/In press) In : Epigenetics. p. 1-10 10 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Angiotensin 1-7 modulates electrophysiological characteristics and calcium homoeostasis in pulmonary veins cardiomyocytes via MAS/PI3K/eNOS signalling pathway

Lu, Y. Y., Wu, W. S., Lin, Y. K., Cheng, C. C., Chen, Y. C., Chen, S. A. & Chen, Y. J., Jan 1 2018, In : European Journal of Clinical Investigation. 48, 1, p. e12854

Research output: Contribution to journalArticle

2 Citations (Scopus)
1 Citation (Scopus)
3 Citations (Scopus)

Factor Xa inhibitors differently modulate electrical activities in pulmonary veins and the sinoatrial node

Chang, C. J., Cheng, C. C., Chen, Y. C., Higa, S., Huang, J. H., Chen, S. A. & Chen, Y. J., Aug 15 2018, In : European Journal of Pharmacology. 833, p. 462-471 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Heart Failure Differentially Modulates the Effects of Ivabradine on the Electrical Activity of the Sinoatrial Node and Pulmonary Veins

Chan, C. S., Chen, Y. C., Chang, S. L., Lin, Y. K., Kao, Y. H., Chen, S. A. & Chen, Y. J., Nov 2018, In : Journal of Cardiac Failure. 24, 11, p. 763-772 10 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Histone deacetylase inhibition attenuates atrial arrhythmogenesis in sterile pericarditis

Chang, C. J., Li, S. J., Chen, Y. C., Huang, S. Y., Chen, S. A. & Chen, Y. J., Oct 2018, In : Translational Research. 200, p. 54-64 11 p.

Research output: Contribution to journalArticle

Hydrogen sulphide increases pulmonary veins and atrial arrhythmogenesis with activation of protein kinase C

Chan, C. S., Lin, Y. K., Kao, Y. H., Chen, Y. C., Chen, S. A. & Chen, Y. J., Jul 2018, In : Journal of Cellular and Molecular Medicine. 22, 7, p. 3503-3513 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2 Citations (Scopus)
1 Citation (Scopus)
2017
6 Citations (Scopus)
5 Citations (Scopus)

ADAM10 modulates calcitriol-regulated RAGE in cardiomyocytes

Lee, T. W., Kao, Y. H., Lee, T. I. & Chen, Y. J., Sep 1 2017, In : European Journal of Clinical Investigation. 47, 9, p. 675-683 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Discrepant effects of heart failure on electrophysiological property in right ventricular outflow tract and left ventricular outflow tract cardiomyocytes

Lu, Y. Y., Cheng, C. C., Tsai, C. F., Lin, Y. K., Lee, T. I., Chen, Y. C., Chen, S. A. & Chen, Y. J., Jun 1 2017, In : Clinical Science. 131, 12, p. 1317-1327 11 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Heart failure modulates electropharmacological characteristics of sinoatrial nodes

Chang, S. L., Chuang, H. L., Chen, Y. C., Kao, Y. H., Lin, Y. K., Yeh, Y. H., Chen, S. A. & Chen, Y. J., Feb 1 2017, In : Experimental and Therapeutic Medicine. 13, 2, p. 771-779 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Mitochondrial dysfunction on sinoatrial node and pulmonary vein electrophysiological activities

Lin, Y. K., Cheng, C. C., Tsai, M. C., Wu, P. Y., Chen, Y. A., Chen, Y. C., Chen, S. A. & Chen, Y. J., May 1 2017, In : Experimental and Therapeutic Medicine. 13, 5, p. 2486-2492 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
1 Citation (Scopus)
4 Citations (Scopus)
2016

2016 Guidelines of the Taiwan Heart Rhythm Society and the Taiwan Society of Cardiology for the management of atrial fibrillation

Chiang, C. E., Wu, T. J., Ueng, K. C., Chao, T. F., Chang, K. C., Wang, C. C., Lin, Y. J., Yin, W. H., Kuo, J. Y., Lin, W. S., Tsai, C. T., Liu, Y. B., Lee, K. T., Lin, L. J., Lin, L. Y., Wang, K. L., Chen, Y-J., Chen, M. C., Cheng, C. C., Wen, M. S. & 7 others, Chen, W. J., Chen, J. H., Lai, W. T., Chiou, C. W., Lin, J. L., Yeh, S. J. & Chen, S. A., Nov 1 2016, In : Journal of the Formosan Medical Association. 115, 11, p. 893-952 60 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

B-Type Natriuretic Peptide Modulates Pulmonary Vein Arrhythmogenesis: A Novel Potential Contributor to the Genesis of Atrial Tachyarrhythmia in Heart Failure

Lin, Y-K., Chen, Y. C., Chen, Y. A., Yeh, Y. H., Chen, S. A. & Chen, Y-J., Dec 1 2016, In : Journal of Cardiovascular Electrophysiology. 27, 12, p. 1462-1471 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Colchicine modulates calcium homeostasis and electrical property of HL-1 cells

Lu, Y. Y., Chen, Y. C., Kao, Y. H., Lin, Y. K., Yeh, Y. H., Chen, S. A. & Chen, Y. J., 2016, (Accepted/In press) In : Journal of Cellular and Molecular Medicine.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Collagen regulates transforming growth factor-β receptors of HL-1 cardiomyocytes through activation of stretch and integrin signaling

Lu, Y. Y., Lin, Y. K., Kao, Y. H., Chung, C. C., Yeh, Y. H., Chen, S. A. & Chen, Y. J., Oct 1 2016, In : Molecular Medicine Reports. 14, 4, p. 3429-3436 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
17 Citations (Scopus)
9 Citations (Scopus)

Gap junction modifiers regulate electrical activities of the sinoatrial node and pulmonary vein: Therapeutic implications in atrial arrhythmogenesis

Chang, C. J., Cheng, C. C., Chen, Y. C., Kao, Y. H., Chen, S. A. & Chen, Y. J., Oct 15 2016, In : International Journal of Cardiology. 221, p. 529-536 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Glucagon-like peptide-1 regulates calcium homeostasis and electrophysiological activities of HL-1 cardiomyocytes

Huang, J. H., Chen, Y. C., Lee, T. I., Kao, Y. H., Chazo, T. F., Chen, S. A. & Chen, Y. J., Apr 1 2016, In : Peptides. 78, p. 91-98 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

HDAC inhibition modulates cardiac PPARs and fatty acid metabolism in diabetic cardiomyopathy

Lee, T. I., Kao, Y. H., Tsai, W. C., Chung, C. C., Chen, Y. C. & Chen, Y. J., 2016, In : PPAR Research. 2016, 5938740.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Latrunculin B modulates electrophysiological characteristics and arrhythmogenesis in pulmonary vein cardiomyocytes

Lu, Y. Y., Lin, Y-K., Wen, Z. H., Chen, Y. C., Chen, S. A. & Chen, Y-J., May 1 2016, In : Clinical Science. 130, 9, p. 721-732 12 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Pathophysiology of cancer therapy-provoked atrial fibrillation

Cheng, W. L., Kao, Y. H., Chen, S. A. & Chen, Y. J., Sep 15 2016, In : International Journal of Cardiology. 219, p. 186-194 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Pericardial fat is associated with the risk of ventricular arrhythmia in asian patients

Tam, W. C., Lin, Y. K., Chan, W. P., Huang, J. H., Hsieh, M. H., Chen, S. A. & Chen, Y. J., 2016, In : Circulation Journal. 80, 8, p. 1726-1733 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Pleiotropic Effects of Myocardial MMP-9 Inhibition to Prevent Ventricular Arrhythmia

Weng, C. H., Chung, F. P., Chen, Y. C., Lin, S. F., Huang, P. H., Kuo, T. B. J., Hsu, W. H., Su, C. W., Sung, Y. L., Lin, Y. J., Chang, S. L., Chou, L. W., Yeh, H. I., Chen, Y-J., Hong, Y. R., Chen, S. A. & Hu, Y. F., Dec 14 2016, In : Scientific Reports. 6, 38894.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Renal failure induces atrial arrhythmogenesis from discrepant electrophysiological remodeling and calcium regulation in pulmonary veins, sinoatrial node, and atria

Huang, S. Y., Chen, Y. C., Kao, Y. H., Hsieh, M. H., Chen, Y. A., Chen, W. P., Lin, Y. K., Chen, S. A. & Chen, Y. J., Jan 1 2016, In : International Journal of Cardiology. 202, p. 846-857 12 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Rhodiola Inhibits Atrial Arrhythmogenesis in a Heart Failure Model

Liu, S. H., Hsiao, Y. W., Chong, E., Singhal, R., Fong, M. C., Tsai, Y. N., Hsu, C. P., Chen, Y. C., Chen, Y. J., Chiou, C. W., Chiang, S. J., Chang, S. L. & Chen, S. A., Sep 1 2016, In : Journal of Cardiovascular Electrophysiology. 27, 9, p. 1093-1101 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Targeting histone deacetylases: A novel therapeutic strategy for atrial fibrillation

Lkhagva, B., Kao, Y. H., Chen, Y. C., Chao, T. F., Chen, S. A. & Chen, Y. J., 2016, In : European Journal of Pharmacology.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Uremic toxins-novel arrhythmogenic factor in chronic kidney disease-related atrial fibrillation

Huang, S. Y., Chen, Y. A., Chen, S. A., Chen, Y. J. & Lin, Y. K., May 1 2016, In : Acta Cardiologica Sinica. 32, 3, p. 259-264 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

ZFHX3 knockdown increases arrhythmogenesis and dysregulates calcium homeostasis in HL-1 atrial myocytes

Kao, Y. H., Hsu, J. C., Chen, Y. C., Lin, Y. K., Lkhagva, B., Chen, S. A. & Chen, Y. J., May 1 2016, In : International Journal of Cardiology. 210, p. 85-92 8 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2015

Ablation of androgen receptor gene triggers right ventricular outflow tract ventricular tachycardia

Tsai, W. C., Lu, Y. Y., Chen, Y. C., Chang, C. J., Kao, Y. H., Lin, Y. K., Chen, Y. H., Chen, S. A., Yang, L. Y. & Chen, Y. J., Aug 1 2015, In : International Journal of Cardiology. 189, 1, p. 172-181 10 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)