If you made any changes in Pure these will be visible here soon.

Research Output 1996 2019

  • 7002 Citations
  • 46 h-Index
  • 272 Article
  • 6 Review article
  • 1 Chapter
  • 1 Comment/debate
2 Citations (Scopus)
Open Access
diabetes mellitus
Streptozocin
Medical problems
rats
Rats
2 Citations (Scopus)
Histone Deacetylases
Transcriptional Activation
Glycogen Synthase Kinase 3
Bone Morphogenetic Proteins
Catenins
1 Citation (Scopus)
Open Access
fibrillation
Pacemakers
Sinoatrial Node
Pulmonary Veins
veins
1 Citation (Scopus)
Bipolar Disorder
Lithium
Drug Therapy
Phosphatidylinositol 3-Kinase
Atrial Remodeling
1 Citation (Scopus)

MicroRNA-133 suppresses ZFHX3-dependent atrial remodelling and arrhythmia

Cheng, W. L., Kao, Y. H., Chao, T. F., Lin, Y. K., Chen, S. A. & Chen, Y. J., Jan 1 2019, (Accepted/In press) In : Acta Physiologica. e13322.

Research output: Contribution to journalArticle

Atrial Remodeling
Homeobox Genes
Zinc Fingers
MicroRNAs
Cardiac Arrhythmias
1 Citation (Scopus)

Sodium hydrosulphide restores tumour necrosis factor-α-induced mitochondrial dysfunction and metabolic dysregulation in HL-1 cells

Lee, T. I., Kao, Y. H., Baigalmaa, L., Lee, T. W., Lu, Y. Y., Chen, Y. C., Chao, T. F. & Chen, Y. J., Jan 1 2019, (Accepted/In press) In : Journal of Cellular and Molecular Medicine.

Research output: Contribution to journalArticle

Open Access
Peroxisome Proliferator-Activated Receptors
Tumor Necrosis Factor-alpha
Adenosine Triphosphate
Cardiac Myocytes
Oxidative Stress

Therapeutic potential of vitamin D in AGE/RAGE-related cardiovascular diseases

Lee, T. W., Kao, Y. H., Chen, Y. J., Chao, T. F. & Lee, T. I., Jan 1 2019, (Accepted/In press) In : Cellular and Molecular Life Sciences.

Research output: Contribution to journalReview article

Vitamin D
Cardiovascular Diseases
Therapeutics
Vascular Stiffness
Advanced Glycosylation End Products
2018
3 Citations (Scopus)

Activation of Class I histone deacetylases contributes to mitochondrial dysfunction in cardiomyocytes with altered complex activities

Lkhagva, B., Kao, Y. H., Lee, T. I., Lee, T. W., Cheng, W. L. & Chen, Y. J., May 1 2018, (Accepted/In press) In : Epigenetics. p. 1-10 10 p.

Research output: Contribution to journalArticle

Histone Deacetylases
Cardiac Myocytes
Tumor Necrosis Factor-alpha
Adenosine Triphosphate
Enzymes
8 Citations (Scopus)

Aging modulates the substrate and triggers remodeling in atrial fibrillation

Lin, Y. K., Chen, Y. A., Lee, T. I., Chen, Y. C., Chen, S. A. & Chen, Y. J., Jan 1 2018, In : Circulation Journal. 82, 5, p. 1237-1244 8 p.

Research output: Contribution to journalReview article

Atrial Fibrillation
Atrial Remodeling
Muscular Diseases
Comorbidity
Veins
2 Citations (Scopus)

Angiotensin 1-7 modulates electrophysiological characteristics and calcium homoeostasis in pulmonary veins cardiomyocytes via MAS/PI3K/eNOS signalling pathway

Lu, Y. Y., Wu, W. S., Lin, Y. K., Cheng, C. C., Chen, Y. C., Chen, S. A. & Chen, Y. J., Jan 1 2018, In : European Journal of Clinical Investigation. 48, 1, p. e12854

Research output: Contribution to journalArticle

Pulmonary Veins
Phosphatidylinositol 3-Kinases
Cardiac Myocytes
Homeostasis
Calcium
1 Citation (Scopus)
Receptor, Fibroblast Growth Factor, Type 1
Histone Deacetylases
Calcitriol
Muscle Cells
Fibroblast Growth Factor 1
Prothrombin Time
Atrial Fibrillation
International Normalized Ratio
Stroke
Rivaroxaban
3 Citations (Scopus)
Factor Xa
Nitric Oxide
Homeostasis
Fibroblasts
Calcium
1 Citation (Scopus)

Factor Xa inhibitors differently modulate electrical activities in pulmonary veins and the sinoatrial node

Chang, C. J., Cheng, C. C., Chen, Y. C., Higa, S., Huang, J. H., Chen, S. A. & Chen, Y. J., Aug 15 2018, In : European Journal of Pharmacology. 833, p. 462-471 10 p.

Research output: Contribution to journalArticle

Sinoatrial Node
Pulmonary Veins
Atrial Fibrillation
Rabbits
Cardiac Myocytes
Vascular Endothelial Growth Factor A
Thromboembolism
Genetic Polymorphisms
Vasoconstriction
Cardiac Myocytes
3 Citations (Scopus)

Heart Failure Differentially Modulates the Effects of Ivabradine on the Electrical Activity of the Sinoatrial Node and Pulmonary Veins

Chan, C. S., Chen, Y. C., Chang, S. L., Lin, Y. K., Kao, Y. H., Chen, S. A. & Chen, Y. J., Jan 1 2018, (Accepted/In press) In : Journal of Cardiac Failure.

Research output: Contribution to journalArticle

ivabradine
Sinoatrial Node
Pulmonary Veins
Heart Failure
Atrial Fibrillation

Histone deacetylase inhibition attenuates atrial arrhythmogenesis in sterile pericarditis

Chang, C. J., Li, S. J., Chen, Y. C., Huang, S. Y., Chen, S. A. & Chen, Y. J., Jan 1 2018, (Accepted/In press) In : Translational Research.

Research output: Contribution to journalArticle

Histone Deacetylases
Pericarditis
Pulmonary Veins
Heart Atria
Atrial Fibrillation
1 Citation (Scopus)
Hydrogen Sulfide
Pulmonary Veins
Protein Kinase C
Heart Atria
Atrial Fibrillation
2 Citations (Scopus)
Sinoatrial Node
Pulmonary Veins
Heart Atria
Type 3 Cyclic Nucleotide Phosphodiesterases
Milrinone
21 Citations (Scopus)

Sex differences in cardiac arrhythmia: A consensus document of the european heart rhythm association, endorsed by the heart rhythm society and Asia pacific heart rhythm society

ESC Scientific Document Group, Jan 1 2018, In : Europace. 20, 10, p. 1565-1565ao

Research output: Contribution to journalReview article

Open Access
Cardiac Resynchronization Therapy
Implantable Defibrillators
Thromboembolism
Sudden Death
Sex Characteristics
1 Citation (Scopus)
Diphosphonates
Vitamin D
Atrial Fibrillation
Osteoporosis
Population
2017
6 Citations (Scopus)
Mitogen-Activated Protein Kinases
Heart Atria
Collagen
Fibroblasts
Fibrosis
4 Citations (Scopus)
Histone Acetyltransferases
Down-Regulation
Osteogenesis
Osteocalcin
Alkaline Phosphatase
5 Citations (Scopus)

ADAM10 modulates calcitriol-regulated RAGE in cardiomyocytes

Lee, T. W., Kao, Y. H., Lee, T. I. & Chen, Y. J., Sep 1 2017, In : European Journal of Clinical Investigation. 47, 9, p. 675-683 9 p.

Research output: Contribution to journalArticle

Disintegrins
Calcitriol Receptors
Calcitriol
Metalloproteases
Cardiac Myocytes
1 Citation (Scopus)

Discrepant effects of heart failure on electrophysiological property in right ventricular outflow tract and left ventricular outflow tract cardiomyocytes

Lu, Y. Y., Cheng, C. C., Tsai, C. F., Lin, Y. K., Lee, T. I., Chen, Y. C., Chen, S. A. & Chen, Y. J., Jun 1 2017, In : Clinical Science. 131, 12, p. 1317-1327 11 p.

Research output: Contribution to journalArticle

Ownership
Cardiac Myocytes
Heart Failure
Action Potentials
Tail
2 Citations (Scopus)

Heart failure modulates electropharmacological characteristics of sinoatrial nodes

Chang, S. L., Chuang, H. L., Chen, Y. C., Kao, Y. H., Lin, Y. K., Yeh, Y. H., Chen, S. A. & Chen, Y. J., Feb 1 2017, In : Experimental and Therapeutic Medicine. 13, 2, p. 771-779 9 p.

Research output: Contribution to journalArticle

Sinoatrial Node
Heart Failure
ivabradine
Rabbits
Action Potentials
1 Citation (Scopus)

Mitochondrial dysfunction on sinoatrial node and pulmonary vein electrophysiological activities

Lin, Y. K., Cheng, C. C., Tsai, M. C., Wu, P. Y., Chen, Y. A., Chen, Y. C., Chen, S. A. & Chen, Y. J., May 1 2017, In : Experimental and Therapeutic Medicine. 13, 5, p. 2486-2492 7 p.

Research output: Contribution to journalArticle

Sinoatrial Node
Pulmonary Veins
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone
Heart Atria
Action Potentials
Atrial Fibrillation
Heart Rate
Ambulatory Monitoring
Ambulatory Electrocardiography
Human Activities
18 Citations (Scopus)

PPARs modulate cardiac metabolism and mitochondrial function in diabetes

Lee, T. W., Bai, K. J., Lee, T. I., Chao, T. F., Kao, Y. H. & Chen, Y. J., Jan 10 2017, In : Journal of Biomedical Science. 24, 1, 5.

Research output: Contribution to journalReview article

Diabetic Cardiomyopathies
Peroxisome Proliferator-Activated Receptors
Medical problems
Metabolism
Mitochondria
2 Citations (Scopus)
Pulmonary Veins
Cyclic AMP-Dependent Protein Kinases
Chronic Renal Insufficiency
Cardiac Myocytes
Oxidation-Reduction
2016
47 Citations (Scopus)

2016 Guidelines of the Taiwan Heart Rhythm Society and the Taiwan Society of Cardiology for the management of atrial fibrillation

Chiang, C. E., Wu, T. J., Ueng, K. C., Chao, T. F., Chang, K. C., Wang, C. C., Lin, Y. J., Yin, W. H., Kuo, J. Y., Lin, W. S., Tsai, C. T., Liu, Y. B., Lee, K. T., Lin, L. J., Lin, L. Y., Wang, K. L., Chen, Y-J., Chen, M. C., Cheng, C. C., Wen, M. S. & 7 others, Chen, W. J., Chen, J. H., Lai, W. T., Chiou, C. W., Lin, J. L., Yeh, S. J. & Chen, S. A., Nov 1 2016, In : Journal of the Formosan Medical Association. 115, 11, p. 893-952 60 p.

Research output: Contribution to journalArticle

Cardiology
Taiwan
Atrial Fibrillation
Guidelines
Committee Membership
1 Citation (Scopus)
Amiodarone
Age Factors
Anti-Arrhythmia Agents
Thyrotropin
Hypothyroidism
4 Citations (Scopus)

B-Type Natriuretic Peptide Modulates Pulmonary Vein Arrhythmogenesis: A Novel Potential Contributor to the Genesis of Atrial Tachyarrhythmia in Heart Failure

Lin, Y-K., Chen, Y. C., Chen, Y. A., Yeh, Y. H., Chen, S. A. & Chen, Y-J., Dec 1 2016, In : Journal of Cardiovascular Electrophysiology. 27, 12, p. 1462-1471 10 p.

Research output: Contribution to journalArticle

Pulmonary Veins
Brain Natriuretic Peptide
Tachycardia
Heart Failure
Cardiac Myocytes
7 Citations (Scopus)

Colchicine modulates calcium homeostasis and electrical property of HL-1 cells

Lu, Y. Y., Chen, Y. C., Kao, Y. H., Lin, Y. K., Yeh, Y. H., Chen, S. A. & Chen, Y. J., 2016, (Accepted/In press) In : Journal of Cellular and Molecular Medicine.

Research output: Contribution to journalArticle

Colchicine
Homeostasis
Calcium
Action Potentials
Potassium
1 Citation (Scopus)

Collagen regulates transforming growth factor-β receptors of HL-1 cardiomyocytes through activation of stretch and integrin signaling

Lu, Y. Y., Lin, Y. K., Kao, Y. H., Chung, C. C., Yeh, Y. H., Chen, S. A. & Chen, Y. J., Oct 1 2016, In : Molecular Medicine Reports. 14, 4, p. 3429-3436 8 p.

Research output: Contribution to journalArticle

Growth Factor Receptors
Transforming Growth Factors
Cardiac Myocytes
Integrins
Collagen
17 Citations (Scopus)
Sinoatrial Node
Hypokalemia
Pulmonary Veins
Hyponatremia
Atrial Fibrillation
8 Citations (Scopus)
Pulmonary Veins
Cardiac Myocytes
Fibroblast Growth Factor 1
Homeostasis
Sodium
5 Citations (Scopus)

Gap junction modifiers regulate electrical activities of the sinoatrial node and pulmonary vein: Therapeutic implications in atrial arrhythmogenesis

Chang, C. J., Cheng, C. C., Chen, Y. C., Kao, Y. H., Chen, S. A. & Chen, Y. J., Oct 15 2016, In : International Journal of Cardiology. 221, p. 529-536 8 p.

Research output: Contribution to journalArticle

Sinoatrial Node
Pulmonary Veins
Gap Junctions
Heptanol
Therapeutics
10 Citations (Scopus)

Glucagon-like peptide-1 regulates calcium homeostasis and electrophysiological activities of HL-1 cardiomyocytes

Huang, J. H., Chen, Y. C., Lee, T. I., Kao, Y. H., Chazo, T. F., Chen, S. A. & Chen, Y. J., Apr 1 2016, In : Peptides. 78, p. 91-98 8 p.

Research output: Contribution to journalArticle

Glucagon-Like Peptide 1
Cardiac Myocytes
Homeostasis
Calcium
Ryanodine Receptor Calcium Release Channel
14 Citations (Scopus)

HDAC inhibition modulates cardiac PPARs and fatty acid metabolism in diabetic cardiomyopathy

Lee, T. I., Kao, Y. H., Tsai, W. C., Chung, C. C., Chen, Y. C. & Chen, Y. J., 2016, In : PPAR Research. 2016, 5938740.

Research output: Contribution to journalArticle

Diabetic Cardiomyopathies
Peroxisome Proliferator-Activated Receptors
Histone Deacetylases
Diabetes Mellitus
Fatty Acids
1 Citation (Scopus)

Latrunculin B modulates electrophysiological characteristics and arrhythmogenesis in pulmonary vein cardiomyocytes

Lu, Y. Y., Lin, Y-K., Wen, Z. H., Chen, Y. C., Chen, S. A. & Chen, Y-J., May 1 2016, In : Clinical Science. 130, 9, p. 721-732 12 p.

Research output: Contribution to journalArticle

Pulmonary Veins
Cardiac Myocytes
Atrial Fibrillation
Polymerization
Actins
5 Citations (Scopus)

Pathophysiology of cancer therapy-provoked atrial fibrillation

Cheng, W. L., Kao, Y. H., Chen, S. A. & Chen, Y. J., Sep 15 2016, In : International Journal of Cardiology. 219, p. 186-194 9 p.

Research output: Contribution to journalArticle

Atrial Fibrillation
Neoplasms
Therapeutics
Antineoplastic Agents
Drug Therapy
4 Citations (Scopus)

Pericardial fat is associated with the risk of ventricular arrhythmia in asian patients

Tam, W. C., Lin, Y. K., Chan, W. P., Huang, J. H., Hsieh, M. H., Chen, S. A. & Chen, Y. J., 2016, In : Circulation Journal. 80, 8, p. 1726-1733 8 p.

Research output: Contribution to journalArticle

Cardiac Arrhythmias
Fats
Ventricular Premature Complexes
Atrial Fibrillation
Coronary Artery Disease
5 Citations (Scopus)

Pleiotropic Effects of Myocardial MMP-9 Inhibition to Prevent Ventricular Arrhythmia

Weng, C. H., Chung, F. P., Chen, Y. C., Lin, S. F., Huang, P. H., Kuo, T. B. J., Hsu, W. H., Su, C. W., Sung, Y. L., Lin, Y. J., Chang, S. L., Chou, L. W., Yeh, H. I., Chen, Y-J., Hong, Y. R., Chen, S. A. & Hu, Y. F., Dec 14 2016, In : Scientific Reports. 6, 38894.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 9
Cardiac Arrhythmias
Calcium
Cyclic AMP-Dependent Protein Kinases
Ryanodine Receptor Calcium Release Channel
10 Citations (Scopus)

Renal failure induces atrial arrhythmogenesis from discrepant electrophysiological remodeling and calcium regulation in pulmonary veins, sinoatrial node, and atria

Huang, S. Y., Chen, Y. C., Kao, Y. H., Hsieh, M. H., Chen, Y. A., Chen, W. P., Lin, Y. K., Chen, S. A. & Chen, Y. J., Jan 1 2016, In : International Journal of Cardiology. 202, p. 846-857 12 p.

Research output: Contribution to journalArticle

Sinoatrial Node
Pulmonary Veins
Renal Insufficiency
Heart Atria
Calcium
2 Citations (Scopus)

Rhodiola Inhibits Atrial Arrhythmogenesis in a Heart Failure Model

Liu, S. H., Hsiao, Y. W., Chong, E., Singhal, R., Fong, M. C., Tsai, Y. N., Hsu, C. P., Chen, Y. C., Chen, Y. J., Chiou, C. W., Chiang, S. J., Chang, S. L. & Chen, S. A., Sep 1 2016, In : Journal of Cardiovascular Electrophysiology. 27, 9, p. 1093-1101 9 p.

Research output: Contribution to journalArticle

Rhodiola
Heart Failure
Heart Atria
Phosphatidylinositol 3-Kinases
Atrial Remodeling
8 Citations (Scopus)

Targeting histone deacetylases: A novel therapeutic strategy for atrial fibrillation

Lkhagva, B., Kao, Y. H., Chen, Y. C., Chao, T. F., Chen, S. A. & Chen, Y. J., 2016, In : European Journal of Pharmacology.

Research output: Contribution to journalArticle

Histone Deacetylases
Atrial Fibrillation
Therapeutics
Atrial Remodeling
Cardiac Arrhythmias
5 Citations (Scopus)

Uremic toxins-novel arrhythmogenic factor in chronic kidney disease-related atrial fibrillation

Huang, S. Y., Chen, Y. A., Chen, S. A., Chen, Y. J. & Lin, Y. K., May 1 2016, In : Acta Cardiologica Sinica. 32, 3, p. 259-264 6 p.

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Atrial Fibrillation
Atrial Remodeling
Cardiovascular System
Cardiac Arrhythmias
13 Citations (Scopus)

ZFHX3 knockdown increases arrhythmogenesis and dysregulates calcium homeostasis in HL-1 atrial myocytes

Kao, Y. H., Hsu, J. C., Chen, Y. C., Lin, Y. K., Lkhagva, B., Chen, S. A. & Chen, Y. J., May 1 2016, In : International Journal of Cardiology. 210, p. 85-92 8 p.

Research output: Contribution to journalArticle

Muscle Cells
Homeostasis
Calcium
Small Interfering RNA
Action Potentials