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Research Output 2008 2019

  • 469 Citations
  • 10 h-Index
  • 14 Article
  • 5 Review article
  • 1 Conference contribution

Phthalate plasticizer di(2-ethyl-hexyl) phthalate induces cyclooxygenase-2 expression in gastric adenocarcinoma cells

Wong, J. H., Wang, Y. S., Nam, S., Ho, K. H., Chang, C. M., Chen, K. C., Chen, Y. F. & Chang, W. C., Jan 1 2019, In : Environmental Toxicology.

Research output: Contribution to journalArticle

Cyclooxygenase 2

Rrm2b deletion causes mitochondrial metabolic defects in renal tubules

Chen, Y. F., Lin, I. H., Guo, Y. R., Chiu, W. J., Wu, M. S., Jia, W. & Yen, Y., Sep 13 2019, In : Scientific Reports. 9, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
Kidney Diseases
DNA Replication
Knockout Mice
2 Citations (Scopus)

Structural insights into the interaction between phytoplasmal effector causing phyllody 1 and MADS transcription factors

Liao, Y. T., Lin, S. S., Lin, S. J., Sun, W. T., Shen, B. N., Cheng, H. P., Lin, C. P., Ko, T. P., Chen, Y. F. & Wang, H. C., Jan 1 2019, (Accepted/In press) In : Plant Journal.

Research output: Contribution to journalArticle

Peanut witches'-broom phytoplasma
Transcription Factors
transcription factors
surface plasmon resonance
3 Citations (Scopus)

Structural insights to the heterotetrameric interaction between the vibrio parahaemolyticus pirA vp and pirB vp toxins and activation of the cry-like pore-forming domain

Lin, S. J., Chen, Y. F., Hsu, K. C., Chen, Y. L., Ko, T. P., Lo, C. F., Wang, H. C. & Wang, H. C., Apr 1 2019, In : Toxins. 11, 4, 233.

Research output: Contribution to journalArticle

Open Access
Vibrio parahaemolyticus
Chemical activation
5 Citations (Scopus)

Anti-TNF-α restricts dengue virus-induced neuropathy

Jhan, M. K., Huangfu, W. C., Chen, Y. F., Kao, J. C., Tsai, T. T., Ho, M. R., Shen, T. J., Tseng, P. C., Wang, Y. T. & Lin, C. F., Jan 1 2018, (Accepted/In press) In : Journal of Leukocyte Biology.

Research output: Contribution to journalArticle

Dengue Virus
Virus Diseases
6 Citations (Scopus)

Skeletal muscle in aged mice reveals extensive transformation of muscle gene expression

Lin, I. H., Chang, J. L., Hua, K., Huang, W. C., Hsu, M. T. & Chen, Y. F., Aug 8 2018, In : BMC Genetics. 19, 1, 55.

Research output: Contribution to journalArticle

Skeletal Muscle
Gene Expression
Quadriceps Muscle
10 Citations (Scopus)

CISD2 Haploinsufficiency Disrupts Calcium Homeostasis, Causes Nonalcoholic Fatty Liver Disease, and Promotes Hepatocellular Carcinoma

Shen, Z. Q., Chen, Y. F., Chen, J. R., Jou, Y. S., Wu, P. C., Kao, C. H., Wang, C. H., Huang, Y. L., Chen, C. F., Huang, T. S., Shyu, Y. C., Tsai, S. F., Kao, L. S. & Tsai, T. F., Nov 21 2017, In : Cell Reports. 21, 8, p. 2198-2211 14 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
20 Citations (Scopus)
Gene expression
8 Citations (Scopus)

Expression of a hepatitis B virus pre-S2 deletion mutant in the liver results in hepatomegaly and hepatocellular carcinoma in mice

Teng, Y. C., Neo, J. C., Wu, J. C., Chen, Y. F., Kao, C. H. & Tsai, T. F., Mar 1 2017, In : Journal of Pathology. 241, 4, p. 463-474 12 p.

Research output: Contribution to journalArticle

Hepatitis B virus
Hepatocellular Carcinoma
Endoplasmic Reticulum
40 Citations (Scopus)

Cisd2 modulates the differentiation and functioning of adipocytes by regulating intracellular Ca2+ homeostasis

Wang, C. H., Chen, Y. F., Wu, C. Y., Wu, P. C., Huang, Y. L., Kao, C. H., Lin, C. H., Kao, L. S., Tsai, T. F. & Wei, Y. H., 2014, In : Human Molecular Genetics. 23, 18, p. 4770-4785 16 p., ddu193.

Research output: Contribution to journalArticle

Wolfram Syndrome
White Adipose Tissue
50 Citations (Scopus)

Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca2+ homeostasis

Wiley, S. E., Andreyev, A. Y., Divakaruni, A. S., Karisch, R., Perkins, G., Wall, E. A., van der Geer, P., Chen, Y. F., Tsai, T. F., Simon, M. I., Neel, B. G., Dixon, J. E. & Murphy, A. N., Jun 2013, In : EMBO Molecular Medicine. 5, 6, p. 904-918 15 p.

Research output: Contribution to journalArticle

Wolfram Syndrome
Unfolded Protein Response
40 Citations (Scopus)

A persistent level of CISD2 extends healthy lifespan and delays aging in mice

Wu, C. Y., Chen, Y. F., Wang, C. H., Kao, C. H., Zhuang, H. W., Chen, C. C., Chen, L. K., Kirby, R., Wei, Y. H., Tsai, S. F. & Tsai, T. F., Sep 2012, In : Human Molecular Genetics. 21, 18, p. 3956-3968 13 p., dds210.

Research output: Contribution to journalArticle

Premature Aging
Medical Genetics
Mitochondrial Membranes
Energy Metabolism
33 Citations (Scopus)

Resveratrol helps recovery from fatty liver and protects against hepatocellular carcinoma induced by hepatitis B virus X protein in a mouse model

Lin, H. C., Chen, Y. F., Hsu, W. H., Yang, C. W., Kao, C. H. & Tsai, T. F., Jul 2012, In : Cancer Prevention Research. 5, 7, p. 952-962 11 p.

Research output: Contribution to journalArticle

Fatty Liver
Hepatocellular Carcinoma
Hepatitis B virus
Transgenic Mice
132 Citations (Scopus)

Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice

Chen, Y. F., Kao, C. H., Chen, Y. T., Wang, C. H., Wu, C. Y., Tsai, C. Y., Liu, F. C., Yang, C. W., Wei, Y. H., Hsu, M. T., Tsai, S. F. & Tsai, T. F., May 15 2009, In : Genes and Development. 23, 10, p. 1183-1194 12 p.

Research output: Contribution to journalArticle

Premature Aging
Knockout Mice