If you made any changes in Pure these will be visible here soon.

Research Output 2008 2019

  • 422 Citations
  • 10 h-Index
  • 14 Article
  • 4 Review article
  • 1 Conference contribution
2019

Phthalate plasticizer di(2-ethyl-hexyl) phthalate induces cyclooxygenase-2 expression in gastric adenocarcinoma cells

Wong, J. H., Wang, Y. S., Nam, S., Ho, K. H., Chang, C. M., Chen, K. C., Chen, Y. F. & Chang, W. C., Jan 1 2019, In : Environmental Toxicology.

Research output: Contribution to journalArticle

Plasticizers
phthalate
Cyclooxygenase 2
Stomach
Adenocarcinoma

Structural insights into the interaction between phytoplasmal effector causing phyllody 1 and MADS transcription factors

Liao, Y. T., Lin, S. S., Lin, S. J., Sun, W. T., Shen, B. N., Cheng, H. P., Lin, C. P., Ko, T. P., Chen, Y. F. & Wang, H. C., Jan 1 2019, (Accepted/In press) In : Plant Journal.

Research output: Contribution to journalArticle

Peanut witches'-broom phytoplasma
Phytoplasma
Transcription Factors
transcription factors
surface plasmon resonance

Structural insights to the heterotetrameric interaction between the vibrio parahaemolyticus pirA vp and pirB vp toxins and activation of the cry-like pore-forming domain

Lin, S. J., Chen, Y. F., Hsu, K. C., Chen, Y. L., Ko, T. P., Lo, C. F., Wang, H. C. & Wang, H. C., Apr 1 2019, In : Toxins. 11, 4, 233.

Research output: Contribution to journalArticle

Open Access
Vibrio parahaemolyticus
Penaeidae
Chemical activation
Necrosis
Hepatopancreas
2018
4 Citations (Scopus)

Anti-TNF-α restricts dengue virus-induced neuropathy

Jhan, M. K., Huangfu, W. C., Chen, Y. F., Kao, J. C., Tsai, T. T., Ho, M. R., Shen, T. J., Tseng, P. C., Wang, Y. T. & Lin, C. F., Jan 1 2018, (Accepted/In press) In : Journal of Leukocyte Biology.

Research output: Contribution to journalArticle

Dengue Virus
Encephalitis
Virus Diseases
Dengue
Neurons
3 Citations (Scopus)

Skeletal muscle in aged mice reveals extensive transformation of muscle gene expression

Lin, I. H., Chang, J. L., Hua, K., Huang, W. C., Hsu, M. T. & Chen, Y. F., Aug 8 2018, In : BMC Genetics. 19, 1, 55.

Research output: Contribution to journalArticle

Skeletal Muscle
Gene Expression
Muscles
Sarcopenia
Quadriceps Muscle

Skeletal muscle in aged mice reveals extensive transformation of muscle gene expression

Lin, I-H., Chang, J-L., Hua, K., Huang, W-C., Hsu, M-T. & Chen, Y-F., Aug 8 2018, In : BMC Genetics. 19, 1, p. 55

Research output: Contribution to journalArticle

Skeletal Muscle
Gene Expression
Muscles
Sarcopenia
Quadriceps Muscle
2017
6 Citations (Scopus)

CISD2 Haploinsufficiency Disrupts Calcium Homeostasis, Causes Nonalcoholic Fatty Liver Disease, and Promotes Hepatocellular Carcinoma

Shen, Z. Q., Chen, Y. F., Chen, J. R., Jou, Y. S., Wu, P. C., Kao, C. H., Wang, C. H., Huang, Y. L., Chen, C. F., Huang, T. S., Shyu, Y. C., Tsai, S. F., Kao, L. S. & Tsai, T. F., Nov 21 2017, In : Cell Reports. 21, 8, p. 2198-2211 14 p.

Research output: Contribution to journalArticle

Haploinsufficiency
Liver
Hepatocellular Carcinoma
Homeostasis
Calcium
15 Citations (Scopus)
Transcriptome
Epigenomics
Gene expression
epigenetics
Liver
5 Citations (Scopus)

Expression of a hepatitis B virus pre-S2 deletion mutant in the liver results in hepatomegaly and hepatocellular carcinoma in mice

Teng, Y. C., Neo, J. C., Wu, J. C., Chen, Y. F., Kao, C. H. & Tsai, T. F., Mar 1 2017, In : Journal of Pathology. 241, 4, p. 463-474 12 p.

Research output: Contribution to journalArticle

Hepatomegaly
Hepatitis B virus
Hepatocellular Carcinoma
Endoplasmic Reticulum
Liver
2014
16 Citations (Scopus)

Cisd2 mediates lifespan: Is there an interconnection among Ca2+ homeostasis, autophagy, and lifespan?

Wang, C. H., Kao, C. H., Chen, Y. F., Wei, Y. H. & Tsai, T. F., 2014, In : Free Radical Research. 48, 9, p. 1109-1114 6 p.

Research output: Contribution to journalReview article

Autophagy
Homeostasis
Genes
Aging of materials
Tungsten
38 Citations (Scopus)

Cisd2 modulates the differentiation and functioning of adipocytes by regulating intracellular Ca2+ homeostasis

Wang, C. H., Chen, Y. F., Wu, C. Y., Wu, P. C., Huang, Y. L., Kao, C. H., Lin, C. H., Kao, L. S., Tsai, T. F. & Wei, Y. H., 2014, In : Human Molecular Genetics. 23, 18, p. 4770-4785 16 p., ddu193.

Research output: Contribution to journalArticle

Adipocytes
Homeostasis
Wolfram Syndrome
White Adipose Tissue
Glucose
2013
49 Citations (Scopus)

Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca2+ homeostasis

Wiley, S. E., Andreyev, A. Y., Divakaruni, A. S., Karisch, R., Perkins, G., Wall, E. A., van der Geer, P., Chen, Y. F., Tsai, T. F., Simon, M. I., Neel, B. G., Dixon, J. E. & Murphy, A. N., Jun 2013, In : EMBO Molecular Medicine. 5, 6, p. 904-918 15 p.

Research output: Contribution to journalArticle

Wolfram Syndrome
Unfolded Protein Response
NAD
Oxidation-Reduction
Homeostasis
2012
36 Citations (Scopus)

A persistent level of CISD2 extends healthy lifespan and delays aging in mice

Wu, C. Y., Chen, Y. F., Wang, C. H., Kao, C. H., Zhuang, H. W., Chen, C. C., Chen, L. K., Kirby, R., Wei, Y. H., Tsai, S. F. & Tsai, T. F., Sep 2012, In : Human Molecular Genetics. 21, 18, p. 3956-3968 13 p., dds210.

Research output: Contribution to journalArticle

Genes
Premature Aging
Medical Genetics
Mitochondrial Membranes
Energy Metabolism
32 Citations (Scopus)

Resveratrol helps recovery from fatty liver and protects against hepatocellular carcinoma induced by hepatitis B virus X protein in a mouse model

Lin, H. C., Chen, Y. F., Hsu, W. H., Yang, C. W., Kao, C. H. & Tsai, T. F., Jul 2012, In : Cancer Prevention Research. 5, 7, p. 952-962 11 p.

Research output: Contribution to journalArticle

Fatty Liver
Hepatocellular Carcinoma
Down-Regulation
Hepatitis B virus
Transgenic Mice
2010
32 Citations (Scopus)

A role for the CISD2 gene in lifespan control and human disease

Chen, Y. F., Wu, C. Y., Kirby, R., Kao, C. H. & Tsai, T. F., Jul 2010, In : Annals of the New York Academy of Sciences. 1201, p. 58-64 7 p.

Research output: Contribution to journalReview article

Genes
Tungsten
Aging of materials
Mitochondrial Genes
Medical Genetics
30 Citations (Scopus)

Longevity and lifespan control in mammals: Lessons from the mouse

Chen, Y. F., Wu, C. Y., Kao, C. H. & Tsai, T. F., Nov 2010, In : Ageing Research Reviews. 9, SUPPL.

Research output: Contribution to journalReview article

Mammals
Aging of materials
Mutation
Genes
Insulin
2009
124 Citations (Scopus)

Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice

Chen, Y. F., Kao, C. H., Chen, Y. T., Wang, C. H., Wu, C. Y., Tsai, C. Y., Liu, F. C., Yang, C. W., Wei, Y. H., Hsu, M. T., Tsai, S. F. & Tsai, T. F., May 15 2009, In : Genes and Development. 23, 10, p. 1183-1194 12 p.

Research output: Contribution to journalArticle

Premature Aging
Mitochondria
Autophagy
Knockout Mice
Genes
31 Citations (Scopus)

Cisd2 mediates mitochondrial integrity and life span in mammals

Chen, Y. F., Kao, C. H., Kirby, R. & Tsai, T. F., Oct 1 2009, In : Autophagy. 5, 7, p. 1043-1045 3 p.

Research output: Contribution to journalReview article

Mammals
Premature Aging
Nerve Degeneration
Mitochondrial Genes
Autophagy
2008
1 Citation (Scopus)

Deformability of mice erythrocytes measured by oscillatory optical tweezers

Huang, Y. S., Yeh, C. L., Liao, G. B., Chen, Y. F., Tsai, T. F. & Chiou, A., 2008, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 7038. 703809

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Optical tweezers
Optical Tweezers
Erythrocyte
erythrocytes
Formability